Lactose intolerance in patients with chronic functional diarrhoea: The role of small intestinal bacterial overgrowth

Alimentary Pharmacology and Therapeutics

Volumn 31, Issue 8, 2010, Pages 892-900

  Zhao, J ^a   Fox, M ^b,c,d   Cong, Y ^a   Chu, H ^a   Shang, Y ^a   Fried, M ^b,d   Dai, N ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c QUEEN S MEDICAL CENTRE   (United Kingdom)

^d UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

LACTOSE;

ABDOMINAL PAIN; ADULT; ARTICLE; BACTERIAL OVERGROWTH; BLOATING; BORBORYGMUS; CECUM; CHRONIC DIARRHEA; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GASTROINTESTINAL SYMPTOM; HUMAN; HYDROGEN BREATH TEST; INTESTINE TRANSIT TIME; LACTOSE INTOLERANCE; MALE; NAUSEA; PREVALENCE; PRIORITY JOURNAL; SMALL INTESTINE;

ADULT; BACTERIAL INFECTIONS; BREATH TESTS; DIARRHEA; FEMALE; HUMANS; HYDROGEN; INTESTINE, SMALL; IRRITABLE BOWEL SYNDROME; LACTOSE INTOLERANCE; LACTULOSE; MALE; MIDDLE AGED;

EID: 77949670324     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/j.1365-2036.2010.04252.x     Document Type: Article

References (57)

1. Flatz G. Genetics of lactose digestion in humans. Adv Hum Genet 1987 16 : 1 77.
2. Sahi T. Genetics and epidemiology of adult-type hypolactasia. Scand J Gastroenterol Suppl 1994 202 : 7 20.
3. Lomer MC, Parkes GC, Sanderson JD. Review article: lactose intolerance in clinical practice - myths and realities. Aliment Pharmacol Ther 2008 27 : 93 103.
4. Hertzler SR, Huynh BC, Savaiano DA. How much lactose is low lactose? J Am Diet Assoc 1996 96 : 243 246.
5. Mishkin S. Dairy sensitivity, lactose malabsorption, and elimination diets in inflammatory bowel disease. Am J Clin Nutr 1997 65 : 564 567.
6. Cuatrecasas P, Lockwood DH, Caldwell JR. Lactase deficiency in the adult. A common occurrence. Lancet 1965 1 : 14 8.
7. Scrimshaw NS, Murray EB. The acceptability of milk and milk products in populations with a high prevalence of lactose intolerance. Am J Clin Nutr 1988 48 (4 Suppl 1079 1159.
8. Vesa TH, Marteau P, Korpela R. Lactose intolerance. J Am Coll Nutr 2000 19 (2 Suppl 165S 75S.
9. Jussila J, Isokoski M, Launiala K. Prevalence of lactose malabsorption in a Finnish rural population. Scand J Gastroenterol 1970 5 : 49 56.
10. Suarez FL, Savaiano DA. Lactose digestion and tolerance in adult and elderly Asian-Americans. Am J Clin Nutr 1994 59 : 1021 1024.
11. Krause JKI, Erckenbrecht JF. Lactose malabsorption produces more symptoms in women than in men. Gastroenterology 1996 110 (Suppl A339.
12. Jussila J. Milk intolerance and lactose malabsorption in hospital patients and young servicemen in Finland. Ann Clin Res 1969 1 : 199 207.
13. Almeida JA, Kim R, Stoita A, McIver CJ, Kurtovic J, Riordan SM. Lactose malabsorption in the elderly: role of small intestinal bacterial overgrowth. Scand J Gastroenterol 2008 43 : 146 154.
14. Yamada T, Alpers DH. Textbook of Gastroenterology, 4th edn. Philadelphia : Lippincott Williams & Wilkins, 2003.
15. Bond JH Jr., Levitt MD. Use of pulmonary hydrogen (H 2) measurements to quantitate carbohydrate absorption. Study of partially gastrectomized patients. J Clin Invest 1972 51 : 1219 1225.
16. Ladas S, Papanikos J, Arapakis G. Lactose malabsorption in Greek adults: correlation of small bowel transit time with the severity of lactose intolerance. Gut 1982 23 : 968 973.
17. Malagelada JR. Lactose intolerance. N Engl J Med 1995 333 : 53 4.
18. Di Stefano M, Miceli E, Mazzocchi S, Tana P, Moroni F, Corazza GR. Visceral hypersensitivity and intolerance symptoms in lactose malabsorption. Neurogastroenterol Motil 2007 19 : 887 895.
19. Suarez FL, Savaiano D, Arbisi P, Levitt MD. Tolerance to the daily ingestion of two cups of milk by individuals claiming lactose intolerance. Am J Clin Nutr 1997 65 : 1502 1506.
20. Addolorato G, Marsigli L, Capristo E, Caputo F, Dall'Aglio C, Baudanza P. Anxiety and depression: a common feature of health care seeking patients with irritable bowel syndrome and food allergy. Hepato-gastroenterology 1998 45 : 1559 1564.
21. Whitehead WE, Bosmajian L, Zonderman AB, Costa PT Jr., Schuster MM. Symptoms of psychologic distress associated with irritable bowel syndrome. Comparison of community and medical clinic samples. Gastroenterology 1988 95 : 709 714.
22. Bozzani A, Penagini R, Velio P, et al. Lactose malabsorption and intolerance in Italians. Clinical implications. Dig Dis Sci 1986 31 : 1313 1316.
23. Farup PG, Monsbakken KW, Vandvik PO. Lactose malabsorption in a population with irritable bowel syndrome: prevalence and symptoms. A case-control study. Scand J Gastroenterol 2004 39 : 645 649.
24. Simren M, Stotzer PO. Use and abuse of hydrogen breath tests. Gut 2006 55 : 297 303.
25. Gupta D, Ghoshal UC, Misra A, Choudhuri G, Singh K. Lactose intolerance in patients with irritable bowel syndrome from northern India: a case-control study. J Gastroenterol Hepatol 2007 22 : 2261 2265.
26. Vanner S. The small intestinal bacterial overgrowth. Irritable bowel syndrome hypothesis: implications for treatment. Gut 2008 57 : 1315 1321.
27. Nucera G, Gabrielli M, Lupascu A, et al. Abnormal breath tests to lactose, fructose and sorbitol in irritable bowel syndrome may be explained by small intestinal bacterial overgrowth. Aliment Pharmacol Ther 2005 21 : 1391 1395.
28. Pimentel M, Kong Y, Park S. Breath testing to evaluate lactose intolerance in irritable bowel syndrome correlates with lactulose testing and may not reflect true lactose malabsorption. Am J Gastroenterol 2003 98 : 2700 2704.
29. Teo M, Chung S, Chitti L, et al. Small bowel bacterial overgrowth is a common cause of chronic diarrhea. J Gastroenterol Hepatol 2004 19 : 904 909.
30. Fan X, Sellin JH. Review article: small intestinal bacterial overgrowth, bile acid malabsorption and gluten intolerance as possible causes of chronic watery diarrhoea. Aliment Pharmacol Ther 2009 29 : 1069 1077.
31. Thomas PD, Forbes A, Green J, et al. Guidelines for the investigation of chronic diarrhoea, 2nd edition. Gut 2003 52 (Suppl 5 v1 15.
32. Chang JY, Locke GR 3rd., Schleck CD, Zinsmeister AR, Talley NJ. Risk factors for chronic diarrhoea in the community in the absence of irritable bowel syndrome. Neurogastroenterol Motil 2009 21 : 1060 e87.
33. Anderson IH, Levine AS, Levitt MD. Incomplete absorption of the carbohydrate in all-purpose wheat flour. N Engl J Med 1981 304 : 891 892.
34. Thompson DG, Binfield P, De Belder A, O'Brien J, Warren S, Wilson M. Extra intestinal influences on exhaled breath hydrogen measurements during the investigation of gastrointestinal disease. Gut 1985 26 : 1349 1352.
35. Di Stefano M, Veneto G, Malservisi S, Strocchi A, Corazza GR. Lactose malabsorption and intolerance in the elderly. Scand J Gastroenterol 2001 36 : 1274 1278.
36. Cong Y, Fox M, Shang Y, et al. Should more attention be paid to lactose intolerance in patients with irritable bowel syndrome in China? Gut 2009 58 (Suppl II A183.
37. 2-breath testing in gastrointestinal diseases: the Rome Consensus Conference. Aliment Pharmacol Ther 2009 29 (Suppl 1 1 49.
38. 2) concentrations to quantify carbohydrate malabsorption by means of lactulose standards. Gut 1990 31 : 37 42.
39. Riordan SM, McIver CJ, Walker BM, Duncombe VM, Bolin TD, Thomas MC. The lactulose breath hydrogen test and small intestinal bacterial overgrowth. Am J Gastroenterol 1996 91 : 1795 1803.
40. Bonapace ES, Maurer AH, Davidoff S, Krevsky B, Fisher RS, Parkman HP. Whole gut transit scintigraphy in the clinical evaluation of patients with upper and lower gastrointestinal symptoms. Am J Gastroenterol 2000 95 : 2838 2847.
41. Miller MA, Parkman HP, Urbain JL, et al. Comparison of scintigraphy and lactulose breath hydrogen test for assessment of orocecal transit: lactulose accelerates small bowel transit. Dig Dis Sci 1997 42 : 10 8.
42. Maurer AH, Krevsky B. Whole-gut transit scintigraphy in the evaluation of small-bowel and colon transit disorders. Semin Nucl Med 1995 25 : 326 338.
43. Drossman DA. The functional gastrointestinal disorders and the Rome III process. Gastroenterology 2006 130 : 1377 1390.
44. Cappello G, Marzio L. Rifaximin in patients with lactose intolerance. Dig Liver Dis 2005 37 : 316 319.
45. Sharara AI, Aoun E, Abdul-Baki H, Mounzer R, Sidani S, Elhajj I. A randomized double-blind placebo-controlled trial of rifaximin in patients with abdominal bloating and flatulence. Am J Gastroenterol 2006 101 : 326 333.
46. Serra J, Azpiroz F, Malagelada JR. Impaired transit and tolerance of intestinal gas in the irritable bowel syndrome. Gut 2001 48 : 14 9.
47. Pimentel M, Mayer AG, Park S, Chow EJ, Hasan A, Kong Y. Methane production during lactulose breath test is associated with gastrointestinal disease presentation. Dig Dis Sci 2003 48 : 86 92.
48. Vanner S. The lactulose breath test for diagnosing SIBO in IBS patients: another nail in the coffin. Am J Gastroenterol 2008 103 : 964 965.
49. Shepherd SJ, Gibson PR. Fructose malabsorption and symptoms of irritable bowel syndrome: guidelines for effective dietary management. J Am Diet Assoc 2006 106 : 1631 1639.
50. Vonk RJ, Priebe MG, Koetse HA, et al. Lactose intolerance: analysis of underlying factors. Eur J Clin Invest 2003 33 : 70 5.
51. King CE, Toskes PP. Small intestine bacterial overgrowth. Gastroenterology 1979 76 (5 Pt 1 1035 1055.
52. Di Stefano M, Miceli E, Missanelli A, Mazzocchi S, Corazza GR. Absorbable vs. non-absorbable antibiotics in the treatment of small intestine bacterial overgrowth in patients with blind-loop syndrome. Aliment Pharmacol Ther 2005 21 : 985 992.
53. Pimentel M, Chow EJ, Lin HC. Eradication of small intestinal bacterial overgrowth reduces symptoms of irritable bowel syndrome. Am J Gastroenterol 2000 95 : 3503 3506.
54. Bratten JR, Spanier J, Jones MP. Lactulose breath testing does not discriminate patients with irritable bowel syndrome from healthy controls. Am J Gastroenterol 2008 103 : 958 963.
55. Parker TJ, Woolner JT, Prevost AT, Tuffnell Q, Shorthouse M, Hunter JO. Irritable bowel syndrome: is the search for lactose intolerance justified? Eur J Gastroenterol Hepatol 2001 13 : 219 225.
56. Shepherd SJ, Parker FC, Muir JG, Gibson PR. Dietary triggers of abdominal symptoms in patients with irritable bowel syndrome: randomized placebo-controlled evidence. Clin Gastroenterol Hepatol 2008 6 : 765 771.
57. Spiegel BM, Chey WD, Chang L. Bacterial overgrowth and irritable bowel syndrome: unifying hypothesis or a spurious consequence of proton pump inhibitors? Am J Gastroenterol 2008 103 : 2972 2976.