Low digit ratio 2D:4D in alcohol dependent patients

PLoS ONE

Volumn 6, Issue 4, 2011, Pages

  Kornhuber, Johannes ^a   Erhard, Gabriele ^a   Lenz, Bernd ^a   Kraus, Thomas ^a,b   Sperling, Wolfgang ^a   Bayerlein, Kristina ^a   Biermann, Teresa ^a   Stoessel, Christina ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b Frankenalbklinik Engelthal ^*  (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALCOHOLISM; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; FEMALE; FINGER; GENETIC POLYMORPHISM; HANDEDNESS; HUMAN; MAJOR CLINICAL STUDY; MALE; RECEIVER OPERATING CHARACTERISTIC; RELIABILITY; SENSITIVITY AND SPECIFICITY; SEX DIFFERENCE; AGED; HISTOLOGY; MIDDLE AGED; PATHOPHYSIOLOGY;

ADULT; AGED; ALCOHOLISM; FEMALE; FINGERS; HUMANS; MALE; MIDDLE AGED; YOUNG ADULT;

EID: 79955549982     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019332     Document Type: Article

References (35)

1. Manning JT, Scutt D, Wilson J, Lewis-Jones DI, (1998) The ratio of 2nd to 4th digit length: a predictor of sperm numbers and concentrations of testosterone, luteinizing hormone and oestrogen. Hum Reprod 13: 3000-3004.
2. McFadden D, Shubel E, (2002) Relative lengths of fingers and toes in human males and females. Horm Behav 42: 492-500 S0018506X02918337 [pii].
3. Malas MA, Dogan S, Evcil EH, Desdicioglu K, (2006) Fetal development of the hand, digits and digit ratio (2D:4D). Early Hum Dev 82: 469-475.
4. Hönekopp J, Watson S, (2010) Meta-analysis of digit ratio 2D:4D shows greater sex difference in the right hand. Am J Hum Biol 22: 619-630 doi:10.1002/ajhb.21054.
5. Bourne VJ, Gray DL, (2009) Hormone exposure and functional lateralisation: Examining the contributions of prenatal and later life hormonal exposure. Psychoneuroendocrinology 34: 1214-1221 S0306-4530(09)00093-6 [pii]; doi:10.1016/j.psyneuen.2009.03.010.
6. Breedlove SM, (2010) Minireview: Organizational hypothesis: instances of the fingerpost. Endocrinology 151: 4116-4122 en.2010-0041 [pii];doi:10.1210/en.2010-0041.
7. Forstmeier W, Mueller JC, Kempenaers B, (2010) A polymorphism in the oestrogen receptor gene explains covariance between digit ratio and mating behaviour. Proc Biol Sci 277: 3353-3361 rspb.2010.1007 [pii]; doi:10.1098/rspb.2010.1007.
8. Jackson CP, Matthews G, (1988) The prediction of habitual alcohol use from alcohol related expectancies and personality. Alcohol Alcohol 23: 305-314.
9. Lex BW, (1991) Some gender differences in alcohol and polysubstance users. Health Psychol 10: 121-132.
10. Manning JT, Peters M, (2009) Digit ratio (2D:4D) and hand preference for writing in the BBC Internet Study. Laterality 14: 528-540 908297008 [pii];doi:10.1080/13576500802637872.
11. Beaton AA, Rudling N, Kissling C, Taurines R, Thome J, (2010) Digit ratio (2D:4D), salivary testosterone, and handedness. Laterality pp. 1-20 918713089 [pii];doi:10.1080/13576500903410369.
12. Fink B, Manning JT, Neave N, Tan U, (2004) Second to fourth digit ratio and hand skill in Austrian children. Biol Psychol 67: 375-384 doi:10.1016/j.biopsycho.2004.03.012.
13. Jackson C, (2008) Prediction of hemispheric asymmetry as measured by handedness from digit length and 2D:4D digit ratio. Laterality 13: 34-50.
14. London WP, Kibbee P, Holt L, (1985) Handedness and alcoholism. J Nerv Ment Dis 173: 570-572.
15. Poikolainen K, (2000) Risk factors for alcohol dependence: a case-control study. Alcohol Alcohol 35: 190-196.
16. Stevenson JC, Everson PM, Williams DC, Hipskind G, Grimes M, et al. (2007) Attention deficit/hyperactivity disorder (ADHD) symptoms and digit ratios in a college sample. Am J Hum Biol 19: 41-50 doi:10.1002/ajhb.20571.
17. Ohlmeier MD, Peters K, Te Wildt BT, Zedler M, Ziegenbein M, et al. (2008) Comorbidity of alcohol and substance dependence with attention-deficit/hyperactivity disorder (ADHD). Alcohol Alcohol 43: 300-304.
18. Hurd PL, Vaillancourt KL, Dinsdale NL, (2010) Aggression, digit ratio and variation in androgen receptor and monoamine oxidase A genes in men. Behav Genet in press. doi:10.1007/s10519-010-9404-7.
19. Bailey AA, Hurd PL, (2005) Finger length ratio (2D:4D) correlates with physical aggression in men but not in women. Biol Psychol 68: 215-222.
20. Williams JHG, Greenhalgh KD, Manning JT, (2003) Second to fourth finger ratio and possible precursors of developmental psychopathology in preschool children. Early Hum Dev 72: 57-65 S0378378203000124 [pii].
21. Wills TA, Vaccaro D, McNamara G, (1994) Novelty seeking, risk taking, and related constructs as predictors of adolescent substance use: An application of Cloninger's theory. J Subst Abuse 6: 1-20 S0899-3289(94)90039-6 [pii].
22. Brennan AF, Walfish S, AuBuchon P, (1986) Alcohol use and abuse in college students. I. A review of individual and personality correlates. Int J Addict 21: 449-474.
23. Manning JT, Bundred PE, Newton DJ, Flanagan BF, (2003) The second to fourth digit ratio and variation in the androgen receptor gene. Evol Hum Behav 24: 399-405.
24. Lenz B, Jacob C, Frieling H, Jacobi A, Hillemacher T, et al. (2009) Polymorphism of the long polyglutamine tract in the human androgen receptor influences craving of men in alcohol withdrawal. Psychoneuroendocrinology 34: 968-971 S0306-4530(09)00027-4 [pii];doi:10.1016/j.psyneuen.2009.01.009.
25. Müller R, Büttner P, (1994) A critical discussion of intraclass correlation coefficients. Stat Med 13: 2465-2476.
26. Pierce CA, Block RA, Aguinis H, (2004) Cautionary note on reporting eta-squared values from multifactor ANOVA designs. Educational and Psychological Measurement 64: 916-924.
27. Manning JT, (2002) Digit Ratio: a Pointer to Fertility, Behaviour and Health New Brunswick, New Jersey, London Rutgers University Press.
28. Conigrave KM, Davies P, Haber P, Whitfield JB, (2003) Traditional markers of excessive alcohol use. Addiction 98 (Suppl 2): 31-43.
29. Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, et al. (2003) The STARD statement for reporting studies of diagnostic accuracy: Explanation and elaboration. Clin Chem 49: 7-18.
30. Manning JT, Fink B, (2011) Digit ratio, nicotine and alcohol intake and national rates of smoking and alcohol consumption. Pers Individ Dif 50: 344-348.
31. Manning JT, (2010) Digit ratio (2D:4D), sex differences, allometry, and finger length of 12-30-year olds: Evidence from the British Broadcasting Corporation (BBC) internet study. Am J Hum Biol 22: 604-608 doi:10.1002/ajhb.21051.
32. Romano M, Leoni B, Saino N, (2006) Examination marks of male university students positively correlate with finger length ratios (2D:4D). Biol Psychol 71: 175-182 S0301-0511(05)00076-1 [pii];doi:10.1016/j.biopsycho.2005.03.006.
33. Brosnan MJ, (2006) Digit ratio and faculty membership: Implications for the relationship between prenatal testosterone and academia. Br J Psychol 97: 455-466 doi:10.1348/000712605X85808.
34. Austin EJ, Manning JT, McInroy K, Mathews E, (2002) A preliminary investigation of the associations between personality, cognitive ability and digit ratio. Pers Individ Dif 33: 1115-1124.
35. McMechan AP, O'Leary-Moore SK, Morrison SD, Hannigan JH, (2004) Effects of prenatal alcohol exposure on forepaw digit length and digit ratios in rats. Dev Psychobiol 45: 251-258 10.1002/dev.20035.