Zfat is a critical molecule for cell survival in mouse Embryonic Fibroblasts

Cellular and Molecular Biology Letters

Volumn 16, Issue 1, 2011, Pages 89-100

  Doi, Keiko ^a   Fujimoto, Takahiro ^a   Koyanagi, Midori ^a   Tsunoda, Toshiyuki ^a   Tanaka, Yoko ^a   Yoshida, Yasuhiro ^a   Takashima, Yasuo ^a   Kuroki, Masahide ^a   Sasazuki, Takehiko ^b   Shirasawa, Senji ^a  

^a FUKUOKA UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

Apoptosis; Gene expression; MEFs; Transcription factor; ZFAT

Indexed keywords

INTERLEUKIN 6; INTERLEUKIN 6 SIGNAL TRANSDUCER; PROTEIN BCL 2; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR TAL1; UNCLASSIFIED DRUG; ZINC FINGER GENE IN AUTOIMMUNE THYROID DISEASE SUSCEPTIBILITY REGION; ZINC FINGER PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; EMBRYO CELL; FIBROBLAST; GENE CONTROL; GENE IDENTIFICATION; IMMUNE RESPONSE; MICROARRAY ANALYSIS; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PROTEIN DEPLETION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 79955549714     PISSN: 14258153     EISSN: 16891392     Source Type: Journal    
DOI: 10.2478/s11658-010-0041-1     Document Type: Article

References (20)

1. Jacobson, E.M. and Tomer, Y. The CD40, CTLA-4, thyroglobulin, TSH receptor, and PTPN22 gene quintet and its contribution to thyroid autoimmunity: back to the future. J. Autoimmun. 28 (2007) 85-98.
2. Sakai, K., Shirasawa, S., Ishikawa, N., Ito, K., Tamai, H., Kuma, K., Akamizu, T., Tanimura, M., Furugaki, K., Yamamoto, K. and Sasazuki, T. Identification of susceptibility loci for autoimmune thyroid disease to 5q31-q33 and Hashimoto's thyroiditis to 8q23-q24 by multipoint affected sib-pair linkage analysis in Japanese. Hum. Mol. Genet. 10 (2001) 1379-1386.
3. Shirasawa, S., Harada, H., Furugaki, K., Akamizu, T., Ishikawa, N., Ito, K., Tamai, H., Kuma, K., Kubota, S., Hiratani, H., Tsuchiya, T., Baba, I., Ishikawa, M., Tanaka, M., Sakai, K., Aoki, M., Yamamoto, K. and Sasazuki, T. SNPs in the promoter of a B cell-specific antisense transcript, SAS-ZFAT, determine susceptibility to autoimmune thyroid disease. Hum. Mol. Genet. 13 (2004) 2221-2231.
4. Koyanagi, M., Nakabayashi, K., Fujimoto, T., Gu, N., Baba, I., Takashima, Y., Doi, K., Harada, H., Kato, N., Sasazuki, T. and Shirasawa, S. ZFAT expression in B and T lymphocytes and identification of ZFAT-regulated genes. Genomics 91 (2008) 451-457.
5. Fujimoto, T., Doi, K., Koyanagi, M., Tsunoda, T., Takashima, Y., Yoshida, Y., Sasazuki, T. and Shirasawa, S. ZFAT is an antiapoptotic molecule and critical for cell survival in MOLT-4 cells. FEBS Lett. 583 (2009) 568-572.
6. Tsunoda, T., Takashima, Y., Tanaka, Y., Fujimoto, T., Doi, K., Hirose, Y., Koyanagi, M., Yoshida, Y., Okamura, T., Kuroki, M., Sasazuki, T. and Shirasawa, S. Immune-related zinc finger gene ZFAT is an essential transcriptional regulator for hematopoietic differentiation in blood islands. Proc. Natl. Acad. Sci. USA 107 (2010) 14199-14204.
7. Yoshida, Y., Tsunoda, T., Takashima, Y., Fujimoto, T., Doi, K., Sasazuki, T., Kuroki, M., Iwasaki, A. and Shirasawa, S. ZFAT is essential for endothelial cell assembly and the branch point formation of capillary-like structures in an angiogenesis model. Cell. Mol. Biol. Lett. 15 (2010) 541-550.
8. Takeuchi, F., Nabika, T., Isono, M., Katsuya, T., Sugiyama, T., Yamaguchi, S., Kobayashi, S., Yamori, Y., Ogihara, T. and Kato, N. Evaluation of genetic loci influencing adult height in the Japanese population. J. Hum. Genet. 54 (2009) 749-752.
9. Comabella, M., Craig, D.W., Morcillo-Suarez, C., Rio, J., Navarro, A., Fernandez, M., Martin, R. and Montalban, X. Genome-wide scan of 500, 000 single-nucleotide polymorphisms among responders and nonresponders to interferon beta therapy in multiple sclerosis. Arch. Neurol. 66 (2009) 972-978.
10. Chao, D.T. and Korsmeyer, S.J. BCL-2 family: regulators of cell death. Annu. Rev. Immunol. 16 (1998) 395-419.
11. Hirano, T., Nakajima, K. and Hibi, M. Signaling mechanisms through gp130: a model of the cytokine system. Cytokine Growth Factor Rev. 8 (1997) 241-252.
12. Fukada, T., Hibi, M., Yamanaka, Y., Takahashi-Tezuka, M., Fujitani, Y., Yamaguchi, T., Nakajima, K. and Hirano, T. Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis. Immunity 5 (1996) 449-460.
13. Peterson, T.R., Laplante, M., Thoreen, C.C., Sancak, Y., Kang, S.A., Kuehl, W.M., Gray, N.S. and Sabatini, D.M. DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival. Cell 137 (2009) 873-886.
14. Proud, C.G. Dynamic balancing: DEPTOR tips the scales. J. Mol. Cell. Biol. 1(2009) 61-63.
15. Wang, E.S., Teruya-Feldstein, J., Wu, Y., Zhu, Z., Hicklin, D.J. and Moore, M.A. Targeting autocrine and paracrine VEGF receptor pathways inhibits human lymphoma xenografts in vivo. Blood 104 (2004) 2893-2902.
16. Santos, S.C. and Dias, S. Internal and external autocrine VEGF/KDR loops regulate survival of subsets of acute leukemia through distinct signaling pathways. Blood 103 (2004) 3883-3889.
17. Lee, Y.K., Bone, N.D., Strege, A.K., Shanafelt, T.D., Jelinek, D.F. and Kay, N.E. VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia. Blood 104 (2004) 788-794.
18. Bellamy, W.T., Richter, L., Sirjani, D., Roxas, C., Glinsmann-Gibson, B., Frutiger, Y., Grogan, T.M. and List, A.F. Vascular endothelial cell growth factor is an autocrine promoter of abnormal localized immature myeloid precursors and leukemia progenitor formation in myelodysplastic syndromes. Blood 97 (2001) 1427-1434.
19. Das, B., Yeger, H., Tsuchida, R., Torkin, R., Gee, M.F., Thorner, P.S., Shibuya, M., Malkin, D. and Baruchel, S. A hypoxia-driven vascular endothelial growth factor/Flt1 autocrine loop interacts with hypoxiainducible factor-1alpha through mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2 pathway in neuroblastoma. Cancer Res. 65 (2005) 7267-7275.
20. Lee, T.H., Seng, S., Sekine, M., Hinton, C., Fu, Y., Avraham, H.K. and Avraham, S. Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1. PLoS Med. 4 (2007) e186.