Transgenic Expression of Walleye Dermal Sarcoma Virus rv-cyclin (orfA) in Zebrafish does not Result in Tissue Proliferation

Marine Biotechnology

Volumn 13, Issue 2, 2011, Pages 142-150

  Paul, Thomas A ^a   Rovnak, Joel ^b   Quackenbush, Sandra L ^b   Whitlock, Kathleen ^c   Zhan, Huiqing ^d   Gong, Zhiyuan ^d   Spitsbergen, Jan ^e   Bowser, Paul R ^a   Casey, James W ^a  

^a Cornell University ^*  (United States)

^b Veterinary Dentistry and Oral Surgery   (United States)

^c UNIVERSIDAD DE VALPARAÍSO   (Chile)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^e OREGON STATE UNIVERSITY   (United States)

Author keywords

Fish retrovirus; orfA; rv cyclin; Walleye dermal sarcoma; Walleye dermal sarcoma virus; Zebrafish

Indexed keywords

ORFA; RV-CYCLIN; WALLEYE DERMAL SARCOMA; WALLEYE DERMAL SARCOMA VIRUS; ZEBRAFISH;

FISH; GENES; POLYMERASE CHAIN REACTION; VIRUSES;

TUMORS;

VIRUS PROTEIN;

CYPRINID; GENETICALLY MODIFIED ORGANISM; POLYMERASE CHAIN REACTION; TUMOR; VIRUS;

ANIMAL; ANIMAL DISEASE; ARTICLE; CELL PROLIFERATION; FISH DISEASE; GENE EXPRESSION REGULATION; GENE TRANSFER; GENETICS; INJURY; METABOLISM; PATHOLOGY; REGENERATION; RETROVIRUS; SARCOMA; SKIN TUMOR; TAIL; TRANSGENIC ANIMAL; VIROLOGY; VIRUS GENE; ZEBRA FISH;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELL PROLIFERATION; EPSILONRETROVIRUS; FISH DISEASES; GENE EXPRESSION REGULATION, VIRAL; GENE TRANSFER TECHNIQUES; GENES, VIRAL; REGENERATION; SARCOMA; SKIN NEOPLASMS; TAIL; VIRAL PROTEINS; ZEBRAFISH;

DANIO RERIO; STIZOSTEDION VITREUM; WALLEYE DERMAL SARCOMA VIRUS;

EID: 79955548214     PISSN: 14362228     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10126-010-9274-2     Document Type: Article

References (39)

1. Amatruda JF, Patton EE (2008) Genetic models of cancer in zebrafish. Int Rev Cell Mol Biol 271: 1-34.
2. Beckwith LG, Moore JL, Tsao-Wu GS, Harshbarger JC, Cheng KC (2000) Ethylnitrosurea induces neoplasia in zebrafish (Danio rerio). Lab Invest 80: 379-385.
3. Berghmans S, Murphey RD, Wienholds E, Neuberg D, Kutok JL, Fletcher CD, Morris JP, Liu TX, Schulte-Merker S, Kanki JP, Plasterk R, Zon LI, Look AT (2005) tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors. Proc Natl Acad Sci 102: 407-412.
4. Bowser PR, Wooster GA (1991) Regression of dermal sarcoma in adult walleyes (Stizostedion vitreum). J Aqut Anim Health 3: 147-150.
5. Chen J, Jette C, Kanki JP, Aster JC, Look AT, Griffin JD (2007) NOTCH1-induced T-cell leukemia in transgenic zebrafish. Leukemia 21: 462-471.
6. Daniels CC, Rovnak J, Quackenbush SL (2008) Walleye dermal sarcoma virus Orf B functions through receptor for activated C kinase (RACK1) and protein kinase C. Virology 375: 550-560.
7. Driever W, Rangini Z (1993) Characterization of a cell line derived from zebrafish (Brachydanio rerio) embryos. In Vitro Cell Dev Biol Anim 29A: 749-754.
8. Faucherre A, Taylor GS, Overvoorde J, Dixon JE, Hertog J (2008) Zebrafish pten genes have overlapping and non-redundant functions in tumorigenesis and embryonic development. Oncogene 27: 1079-1086.
9. Feitsma H, Cuppen E (2008) Zebrafish as a cancer model. Mol Cancer Res 6: 685-694.
10. Hanahan D, Weinberg RA (2000) The hallmarks of cancer. Cell 100: 57-70.
11. Haramis AP, Hurlstone A, van der Velden Y, Begthel H, van den Born M, Offerhaus GJ, Clevers HC (2006) Adenomatous polyposis coli-deficient zebrafish are susceptible to digestive tract neoplasia. EMBO Rep 7: 444-449.
12. Holzschu DL, Martineau D, Fodor SK, Vogt VM, Bowser PR, Casey JW (1995) Nucleotide sequence and protein analysis of a complex piscine retrovirus, walleye dermal sarcoma virus. J Virol 69: 5320-5331.
13. Ju B, Xu Y, He J, Liao J, Yan T, Hew CL, Lam TJ, Gong Z (1999) Faithful expression of green fluorescent protein (GFP) in transgenic zebrafish embryos under control of zebrafish gene promoters. Dev Genet 25: 158-167.
14. Kent ML, Spitsbergen JM, Matthews, Fournie JW, Westerfield M (2007) Diseases of zebrafish in research facilities. ZIRC Health Services Zebrafish Disease Manual, Zebrafish International Resources Center.
15. Lairmore MD, Stanley JR, Weber SA, Holzschu DL (2000) Squamous epithelial proliferation induced by walleye dermal sarcoma retrovirus cyclin in transgenic mice. Proc Natl Acad Sci 97: 6114-6119.
16. Langenau DM, Traver D, Ferrando AA, Kutok JL, Aster JC, Kanki JP, Lin S, Prochownik E, Trede NS, Zon LI, Look AT (2003) Myc-induced T cell leukemia in transgenic zebrafish. Science 299: 887-890.
17. LaPierre LA, Casey JW, Holzschu DL (1998) Walleye retroviruses associated with skin tumors and hyperplasias encode cyclin D homologs. J Virol 72: 8765-8771.
18. Luna LG (1968) Manual of histological staining methods of the Armed Forces Institute of Pathology, 3rd edn. McGraw Hill Publications, New York.
19. Macleod KF, Jacks T (1999) Insights into cancer from transgenic mouse models. J Pathol 187: 43-60.
20. Martineau D, Bowser PR, Renshaw RR, Casey JW (1992) Molecular characterization of a unique retrovirus associated with a fish tumor. J Virol 66: 596-599.
21. Moore JL, Rush LM, Breneman C, Mohideen MA, Cheng KC (2006) Zebrafish genomic instability mutants and cancer susceptibility. Genetics 174: 585-600.
22. Näf D, Krupke DM, Sundberg JP, Eppig JT, Bult CJ (2002) The mouse tumor biology database: a public resource for cancer genetics and pathology of the mouse. Cancer Res 62: 1235-1240.
23. Poulet FM, Vogt VM, Bowser PR, Casey JW (1995) In situ hybridization and immunohistochemical study of walleye dermal sarcoma virus (WDSV) nucleic acids and proteins in spontaneous sarcomas of adult walleyes (Stizostedion vitreum). Vet Pathol 32: 162-72.
24. Quackenbush SL, Holzschu DL, Bowser PR, Casey JW (1997) Transcriptional analysis of walleye dermal sarcoma virus (WDSV). Virology 237: 107-112.
25. Quackenbush SL, Linton A, Brewster CD, Rovnak J (2009) Walleye dermal sarcoma virus rv-cyclin inhibits NF-kappaB-dependent transcription. Virology 386: 55-60.
26. Rovnak J, Casey JW, Quackenbush SL (2001) Intracellular targeting of walleye dermal sarcoma virus Orf A (rv-cyclin). Virology 280: 31-40.
27. Rovnak J, Quackenbush SL (2002) Walleye dermal sarcoma virus cyclin interacts with components of the mediator complex and the RNA polymerase II holoenzyme. J Virol 76: 8031-8039.
28. Rovnak J, Quackenbush SL (2006) Walleye dermal sarcoma virus retroviral cyclin directly contacts TAF9. J Virol 80: 12041-12048.
29. Rovnak J, Casey RN, Brewster CD, Casey JW, Quackenbush SL (2007) Establishment of productively infected walleye dermal sarcoma explant cells. J Gen Virol 88: 2583-2599.
30. Sabaawy HE, Azuma M, Embree LJ, Tsai HJ, Starost MF, Hickstein DD (2006) TEL-AML1 transgenic zebrafish model of precursor B cell acute lymphoblastic leukemia. Proc Natl Acad Sci 103: 15166-15171.
31. Spitsbergen JM, Kent ML (2003) The state of the art of the zebrafish model for toxicology and toxicologic pathology research-advantages and current limitations. Toxicol Pathol 31S: 62-87.
32. Spitsbergen JM, Tsai H-W, Reddy A, Miller T, Arbogast D, Hendricks JD, Bailey GS (2000a) Neoplsia in zebrafish (Danio rerio) treated with 7, 12-dimethylbenz[a]anthracene by two exposure routes at different developmental stages. Toxicol Pathol 28: 705-715.
33. Spitsbergen JM, Tsai H-W, Reddy A, Miller T, Arbogast D, Hendricks JD, Bailey GS (2000b) Neoplasia in zebrafish (Danio rerio) treated with N-methyl-N′-nitro-N-nitrosoguanidine by three exposure routes at different developmental stages. Toxicol Pathol 28: 716-725.
34. Stern HM, Zon LI (2003) Cancer genetics and drug discovery in the zebrafish. Nat Rev Cancer 3: 1-7.
35. Taylor J, Braasch I, Frickey T, Meyer A, van De Peer Y (2003) Genome duplication, a trait shared by 22, 000 species of ray-finned fish. Genome Res 13: 382-390.
36. Westerfield M (1994) The zebrafish book. A guide for the laboratory use of zebrafish (Brachydanio rerio). University of Oregon Press, Eugene.
37. Winkler C, Hong Y, Wittbrodt J, Schartl M (1992) Analysis of heterologous and homologous promoters and enhancers in vitro and in vivo by gene transfer into Japanese medaka (Oryzias latipes) and Xiphophorus. Mol Mar Biol Biotechnol 1: 326-337.
38. Winkler C, Wittbrodt J, Lammers R, Ullrich A, Schartl M (1994) Ligand-independent tumor induction in medakfish embryos by a Xmrk receptor tyrosine kinase transgene. Oncogene 9: 1517-1525.
39. Zhan H, Spitsbergen JM, Qing W, Wu YL, Paul TA, Casey JW, Her GM, Gong Z (2010). Transgenic expression of walleye dermal sarcoma virus rv-cyclin gene in zebrafish and its suppressive effect on liver tumor development after carcinogen treatment. Marine Biotechnology. doi: 10. 1007/s10126-009-9251-9.