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Volumn 50, Issue 19, 2011, Pages 4488-4491

Benzannulated bicycles by three-component aryne reactions

Author keywords

arynes; heterocycles; isocyanides; multicomponent reactions; polycycles

Indexed keywords

ARYNES; HETEROCYCLES; ISOCYANIDES; MULTI-COMPONENT REACTIONS; POLYCYCLES;

EID: 79955519213     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201100911     Document Type: Article
Times cited : (117)

References (64)
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    • For early examples of multicomponent aryne reactions, see
    • For early examples of multicomponent aryne reactions, see
  • 7
    • 79955494814 scopus 로고    scopus 로고
    • For select examples of multicomponent aryne methodologies to generate 1,2-disubstituted arene scaffolds, see
    • For select examples of multicomponent aryne methodologies to generate 1,2-disubstituted arene scaffolds, see
  • 21
    • 70349783775 scopus 로고    scopus 로고
    • Angew. Chem. Int. Ed. 2009, 48, 3458-3461.
    • (2009) Angew. Chem. Int. Ed. , vol.48 , pp. 3458-3461
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    • 4544320921 scopus 로고    scopus 로고
    • Angew. Chem. Int. Ed. 2004, 43, 3935-3938.
    • (2004) Angew. Chem. Int. Ed. , vol.43 , pp. 3935-3938
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    • 79955496750 scopus 로고    scopus 로고
    • The phenoxy iminoisobenzofuran framework was unambiguously confirmed by obtaining the X-ray crystal structure of phenoxy iminoisobenzofuran 14 r (Table 1). See Supporting Information for details.
    • The phenoxy iminoisobenzofuran framework was unambiguously confirmed by obtaining the X-ray crystal structure of phenoxy iminoisobenzofuran 14 r (Table 1). See Supporting Information for details.
  • 39
    • 79955503565 scopus 로고    scopus 로고
    • The closest related structures include an iminium perchlorate reported by Boyd and a series of cyclic imidates reported by Sato et al. However, these structures are shown to be unstable in the presence of water. See
    • The closest related structures include an iminium perchlorate reported by Boyd and a series of cyclic imidates reported by Sato et al. However, these structures are shown to be unstable in the presence of water. See
  • 44
    • 79955487359 scopus 로고    scopus 로고
    • For results highlighting regioselective additions to unsymmetrical arynes, see
    • For results highlighting regioselective additions to unsymmetrical arynes, see
  • 55
    • 79955517749 scopus 로고    scopus 로고
    • For computational studies of aryne electronic properties, see
    • For computational studies of aryne electronic properties, see
  • 63
    • 79955488437 scopus 로고    scopus 로고
    • Attempts were made to carry out similar transformations using methyl acrylate, methyl methacrylate, 2-cyclopentenone, and 2-cyclohexenone in place of methyl propiolate (19 a). However, each failed to generate the corresponding iminoindanone under the reaction conditions.
    • Attempts were made to carry out similar transformations using methyl acrylate, methyl methacrylate, 2-cyclopentenone, and 2-cyclohexenone in place of methyl propiolate (19 a). However, each failed to generate the corresponding iminoindanone under the reaction conditions.
  • 64
    • 79955494654 scopus 로고    scopus 로고
    • Efforts to employ additional alkynes lacking conjugate acceptors (e.g., cyclohexylacetylene, ethoxyacetylene, and diphenylacetylene) failed to generate the corresponding three-component adducts.
    • Efforts to employ additional alkynes lacking conjugate acceptors (e.g., cyclohexylacetylene, ethoxyacetylene, and diphenylacetylene) failed to generate the corresponding three-component adducts.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.