Blockade of CD27/CD70 pathway to reduce the generation of memory T cells and markedly prolong the survival of heart allografts in presensitized mice

Transplant Immunology

Volumn 24, Issue 4, 2011, Pages 195-202

  Dai, Helong ^a   Chen, Jibing ^a   Shao, Wei ^a   Wang, Feng ^a   Xu, Shuo ^a   Peng, Yuanzheng ^a   Lin, Yingying ^a   Xia, Junjie ^a   Ekberg, Henrik ^b   Wang, Xiaomin ^c   Qi, Zhongquan ^a  

^a XIAMEN UNIVERSITY   (China)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

^c ZHONGSHAN HOSPITAL OF FUDAN UNIVERSITY   (China)

Author keywords

Anti CD70; Costimulatory blockade; Heart transplantation; Memory T cells

Indexed keywords

ALLOANTIBODY; BETA ACTIN; CD27 ANTIGEN; CD40 LIGAND MONOCLONAL ANTIBODY; CD70 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD70; ODULIMOMAB; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY BLOOD LEVEL; ARTICLE; CARDIAC GRAFT REJECTION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; FEMALE; GRAFT RECIPIENT; GRAFT SURVIVAL; HEART TRANSPLANTATION; IMMUNOMODULATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTIC INFILTRATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MEMORY T LYMPHOCYTE; MIXED LYMPHOCYTE REACTION; MOUSE; NONHUMAN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SENSITIZATION; SKIN TRANSPLANTATION; SPLEEN CELL; SURVIVAL TIME;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD70; CD40 LIGAND; CELLS, CULTURED; GRAFT REJECTION; HEART TRANSPLANTATION; HUMANS; IMMUNIZATION; IMMUNOLOGIC MEMORY; IMMUNOTHERAPY; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY; TRANSPLANTATION TOLERANCE;

EID: 79955470860     PISSN: 09663274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trim.2011.02.002     Document Type: Article

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