No association between bipolar disorder risk polymorphisms in ANK3 and CACNA1C and common migraine

Headache

Volumn 51, Issue 5, 2011, Pages 796-803

  Wöber Bingöl, Çiçek ^a   Tropeano, Maria ^b   Karwautz, Andreas ^a   Wagner, Gudrun ^a   Campos De Sousa, Sara ^b   Zesch, Heidi E ^a   Kienbacher, Christian ^a   Natriashvili, Sofia ^a   Kanbur, Incifer ^a   Ray, Munni ^a   Wöber, Christian ^a   Collier, David A ^b  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

bipolar disorder; co morbidity; ion channel; migraine; single nucleotide polymorphism; transmission disequilibrium test

Indexed keywords

ANKYRIN; ANKYRIN G; CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL VOLTAGE DEPENDENT L TYPE ALPHA 1C; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BIPOLAR DISORDER; CHILD; CHILDHOOD DISEASE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE TRANSMISSION; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MIGRAINE WITH AURA; MIGRAINE WITHOUT AURA; PRESCHOOL CHILD; PRIORITY JOURNAL; RISK FACTOR; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; ANKYRINS; BIPOLAR DISORDER; CALCIUM CHANNELS, L-TYPE; CASE-CONTROL STUDIES; CHILD; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; MALE; MIGRAINE WITHOUT AURA; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; YOUNG ADULT;

EID: 79955470204     PISSN: 00178748     EISSN: 15264610     Source Type: Journal    
DOI: 10.1111/j.1526-4610.2011.01858.x     Document Type: Article

References (40)

1. Stovner LJ, Hagen K, Jensen R, et al,. The global burden of headache: A documentation of headache prevalence and disability worldwide. Cephalalgia. 2007; 27: 193-210. (Pubitemid 46354128)
2. Stovner LJ, Zwart JA, Hagen K, et al,. Epidemiology of headache in Europe. Eur J Neurol. 2006; 13: 333-345.
3. Rasmussen BK,. Epidemiology of headache. Cephalalgia. 2001; 21: 774-777. (Pubitemid 34621548)
4. Mulder EJ, van Baal C, Gaist D, et al,. Genetic and environmental influences on migraine: A twin study across six countries. Twin Res. 2003; 6: 422-431. (Pubitemid 38019780)
5. Gervil M, Ulrich V, Kaprio J, et al,. The relative role of genetic and environmental factors in migraine without aura. Neurology. 1999; 53: 995-999. (Pubitemid 29442115)
6. Gervil M, Ulrich V, Kyvik KO, et al,. Migraine without aura: A population-based twin study. Ann Neurol. 1999; 46: 606-611. (Pubitemid 29466439)
7. Ulrich V, Gervil M, Kyvik KO, et al,. Evidence of a genetic factor in migraine with aura: A population-based Danish twin study. Ann Neurol. 1999; 45: 242-246. (Pubitemid 29072371)
8. Hamelsky SW, Lipton RB,. Psychiatric comorbidity of migraine. Headache. 2006; 46: 1327-1333. (Pubitemid 44556425)
9. Baskin SM, Smitherman TA,. Migraine and psychiatric disorders: Comorbidities, mechanisms, and clinical applications. Neurol Sci. 2009; 30 (Suppl. 1): S61-S65.
10. Merikangas KR, Angst J, Isler H,. Migraine and psychopathology. Results of the Zurich cohort study of young adults. Arch Gen Psychiatry. 1990; 47: 849-853. (Pubitemid 20302700)
11. Hirschfeld RMA, Calabrese JR, Weissman MM, et al,. Screening for bipolar disorder in the community. J Clin Psychiatry. 2003; 64: 53-59. (Pubitemid 36182230)
12. McIntyre RS, Konarski JZ, Wilkins K, et al,. The prevalence and impact of migraine headache in bipolar disorder: Results from the Canadian community health survey. Headache. 2006; 46: 973-982. (Pubitemid 43794749)
13. Low NCP, Du Fort GG, Cervantes P,. Prevalence, clinical correlates, and treatment of migraine in bipolar disorder. Headache. 2003; 43: 940-949. (Pubitemid 37238648)
14. Fasmer OB,. The prevalence of migraine in patients with bipolar and unipolar affective disorders. Cephalalgia. 2001; 21: 894-899. (Pubitemid 34621512)
15. Mahmood T, Silverstone T,. Twin concordance for bipolar disorder and migraines. Am J Psychiatry. 2000; 157: 2057.
16. Mahmood T, Romans S, Silverstone T,. Prevalence of migraine in bipolar disorder. J Affect Disord. 1999; 52: 239-241. (Pubitemid 29232055)
17. Dilsaver SC, Benazzi F, Oedegaard KJ, et al,. Is a family history of bipolar disorder a risk factor for migraine among affectively ill patients? Psychopathology. 2009; 42: 119-123.
18. Sklar P, Smoller JW, Fan J, et al,. Whole-genome association study of bipolar disorder. Mol Psychiatry. 2008; 13: 558-569. (Pubitemid 351704939)
19. Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature. 2007; 447: 661-678.
20. Ferreira MAR, O'Donovan MC, Meng YA, et al,. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet. 2008; 40: 1056-1058.
21. Schulze TG, Detera-Wadleigh SD, Akula N, et al,. Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder. Mol Psychiatry. 2009; 14: 487-491.
22. Gargus JJ,. Ion channel functional candidate genes in multigenic neuropsychiatric disease. Biol Psychiatry. 2006; 60: 177-185.
23. Gargus JJ,. Genetic calcium signaling abnormalities in the central nervous system: Seizures, migraine and autism. Ann N Y Acad Sci. 2009; 1151: 133-156.
24. de Vries B, Frants RR, Ferrari MD, van den Maagdenberg AM,. Molecular genetics of migraine. Hum Genet. 2009; 126: 115-132.
25. Wöber-Bingöl C, Wöber C, Karwautz A, et al,. Diagnosis of headache in childhood and adolescence: A study in 437 patients. Cephalalgia. 1995; 15: 13-21.
26. Headache Classification Subcommittee of the International Headache Society. The International Classification of Headache Disorders. 2nd ed. Cephalalgia. 2004; 24 (Suppl. 1): 1-151.
27. Freeman B, Powell J, Ball D, et al,. DNA by mail: An inexpensive and noninvasive method for collecting DNA samples from widely dispersed populations. Behav Genet. 1997; 27: 251-257.
28. Plomin R, Crabbe J,. DNA. Psychol Bull. 2000; 126: 806-828.
29. Dudbridge F,. Pedigree disequilibrium tests for multilocus haplotypes. Genet Epidemiol. 2003; 25: 115-121. (Pubitemid 37064867)
30. Purcell S, Cherny SS, Sham PC,. Genetic Power Calculator: Design of linkage and association genetic mapping studies of complex traits. Bioinformatics. 2003; 19: 149-150. (Pubitemid 36150192)
31. Kordeli E, Lambert S, Bennett V, Ankyrin G,. A new ankyrin gene with neural-specific isoforms localized at the axonal initial segment and node of Ranvier. J Biol Chem. 1995; 270: 2352-2359.
32. Poliak S, Peles E,. The local differentiation of myelinated axons at nodes of Ranvier. Nat Rev Neurosci. 2003; 4: 968-980. (Pubitemid 37486673)
33. Boiko T, Van Wart A, Caldwell JH, et al,. Functional specialization of the axon initial segment by isoform-specific sodium channel targeting. J Neurosci. 2003; 23: 2306-2313. (Pubitemid 36368918)
34. Shirahata E, Iwasaki H, Takagi M, et al,. Ankyrin-G regulates inactivation gating of the neuronal sodium channel, Nav1.6. J Neurophysiol. 2006; 96: 1347-1357. (Pubitemid 44371526)
35. Vacher H, Mohapatra DP, Trimmer JS,. Localization and targeting of voltage-dependent ion channels in mammalian central neurons. Physiol Rev. 2008; 88: 1407-1447.
36. Casamassima F, Hay AC, Benedetti A, et al,. L-type calcium channels and psychiatric disorders: A brief review. Am J Med Genet B Neuropsychiatr Genet. 2010; 153B: 1373-1390.
37. Oedegaard KJ, Greenwood TA, Lunde A, et al,. A genome-wide linkage study of bipolar disorder and co-morbid migraine: Replication of migraine linkage on chromosome 4q24, and suggestion of an overlapping susceptibility region for both disorders on chromosome 20p11. J Affect Disord. 2010; 122: 14-26.
38. Oedegaard KJ, Greenwood TA, Johansson S, et al,. A genome-wide association study of bipolar disorder and comorbid migraine. Genes Brain Behav. 2010; 9: 673-680.
39. International Schizophrenia Consortium, Purcell SM, Wray NR, et al,. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature. 2009; 460: 748-752.
40. Anttila V, Stefansson H, Kallela M, et al,. Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1. Nat Genet. 2010; 42: 869-873.