Gold activates mast cells via calcium influx through multiple H 2O2-sensitive pathways including L-type calcium channels

Free Radical Biology and Medicine

Volumn 50, Issue 10, 2011, Pages 1417-1428

  Hayama, Koremasa ^a   Suzuki, Yoshihiro ^a   Inoue, Toshio ^a   Ochiai, Toyoko ^a   Terui, Tadashi ^a   Ra, Chisei ^a  

^a NIHON UNIVERSITY   (Japan)

Author keywords

Autoimmunity; Free radicals; Gold; Heavy metals; L type Ca2+ channels; Mast cells; Metal allergy; Reactive oxygen species

Indexed keywords

CALCIUM CHANNEL; GOLD; HYDROGEN PEROXIDE; IMMUNOGLOBULIN E ANTIBODY; LEUKOTRIENE C4; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM TRANSPORT; CELL ACTIVATION; CONTROLLED STUDY; EXTRACELLULAR CALCIUM; MAST CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; CALCIUM; CALCIUM CHANNELS, L-TYPE; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; GOLD; HUMANS; HYDROGEN PEROXIDE; MAST CELLS; MICE; MICE, INBRED C57BL; RATS; REACTIVE OXYGEN SPECIES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79955468992     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.02.025     Document Type: Article

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