Effects of a nanocomposite containing Orbignya speciosa lipophilic extract on Benign Prostatic Hyperplasia

Journal of Ethnopharmacology

Volumn 135, Issue 1, 2011, Pages 135-146

  De Souza, Pedro A V Reis ^a,b   Palumbo Jr , Antonio ^a   Alves, Leandro M ^a   De Souza, Valéria Pereira ^c   Cabral, Lúcio M ^c   Fernandes, Patrícia D ^d   Takiya, Christina M ^a   Menezes, Fábio S ^e   Nasciutti, Luiz E ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b HOSPITAL GERAL DE FORTALEZA   (Brazil)

^c Faculdade de Farmacia   (Brazil)

^d Programa de Farmacologia Celular e Molecular   (Brazil)

^e TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Apoptosis; Benign Prostatic Hyperplasia; Cell proliferation; Orbignya speciosa extract; Phytotherapy

Indexed keywords

LACTATE DEHYDROGENASE; ORBIGNYA SPECIOSA NANOCOMPOSITE EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL STRUCTURE; CYTOTOXICITY; DRUG EFFECT; FEMALE; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; ORBIGNYA SPECIOSA; PROSTATE HYPERTROPHY; STROMA CELL;

ANIMALS; APOPTOSIS; ARECACEAE; BRAZIL; CELL PROLIFERATION; CELLS, CULTURED; FEMALE; HUMANS; MALE; MICE; NANOTECHNOLOGY; NECROSIS; PHYTOTHERAPY; PLANT EXTRACTS; PROSTATIC HYPERPLASIA; SEEDS;

ANIMALIA; ORBIGNYA BARBOSIANA;

EID: 79955463159     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2011.03.003     Document Type: Article

References (49)

1. M. Abe, Y. Ito, L. Oyunzul, T. Oki-Fujino, and S. Yamada Pharmacologically relevant receptor binding characteristics and 5alpha-reductase inhibitory activity of free fatty acids contained in saw palmetto extract Biological & Pharmaceutical Bulletin 32 2009 646 650
2. M. Allen, P. Millett, E. Dawes, and N. Rushton Lactate dehydrogenase activity as a rapid and sensitive test for the quantification of cell numbers in vitro Clinical Materials 16 1994 189 194
3. P. Alonso-Magdalena, C. Brössner, A. Reiner, G. Cheng, N. Sugiyama, M. Warner, and J.A. Gustafsson A role for epithelial-mesenchymal transition in the etiology of Benign Prostatic Hyperplasia Proceedings of the National Academy of Sciences 106 2009 2859 2863
4. L. Angervall, and S. Berntsson Oral toxicity of polyvinylpyrrolidone products at low average molecular weight The Journal of the Institute of Brewing & Distilling 67 1961 335 336
5. M.J. Balick The use of palms by the Apinaye and Guajajara Indians of northeastern Brazil Advances in Economic Botany 6 1988 65 90
6. M.A.M. Bandeira, M.E.O. Matos, F.J.A. Matos, and M.B.S. Maia Chemical study of babassu coconut Revista Brasileira de Farmacognosia 1 1986 27 28 (in Portuguese)
7. W.W. Barclay, R.D. Woodruff, M.C. Hall, and S.D. Cramer A system for studying epithelial-stromal interactions reveals distinct inductive abilities of stromal cells from Benign Prostatic Hyperplasia and prostate cancer Endocrinology 146 2005 13 18 (Pubitemid 40051716)
8. M.J. Barry A 73-year-old man with symptomatic Benign Prostatic Hyperplasia The Journal of the American Medical Association 278 1997 2178 2184 24-31 (Pubitemid 28013493)
9. C.W. Bayne, M. Ross, F. Donnelly, and F.K. Habib The selectivity and specificity of the actions of the lipido-sterolic extract of Serenoa repens (Permixon (R)) on the prostate The Journal of Urology 164 2000 876 881 (Pubitemid 30637649)
10. S. Bent, C. Kane, K. Shinohara, J. Neuhaus, E.S. Hudes, H. Goldberg, and A.L. Avins Saw palmetto for Benign Prostatic Hyperplasia The New England Journal of Medicine 354 2006 557 566 (Pubitemid 43209103)
11. S.J. Berry, D.S. Coffey, P.C. Walsh, and L.L. Ewing The development of human Benign Prostatic Hyperplasia with age The Journal of Urology 132 1984 474 479 (Pubitemid 14026148)
12. D. Boulbs, L. Soustelle, P. Costa, M. Haddoum, J.P. Bali, F. Hollande, and R. Magous Pygeum africanum extract inhibits proliferation of human cultured prostatic fibroblasts and myofibroblasts British Journal of Urology International 98 2006 1106 1113 (Pubitemid 44536467)
13. P. Boyle, C. Robertson, F. Lowe, and C. Roehrborn Updated meta-analysis of clinical trials of Serenoa repens extract in the treatment of symptomatic Benign Prostatic Hyperplasia British Journal of Urology International 93 2004 751 756 (Pubitemid 38497023)
14. A. Bozec, A. Ruffion, M. Decaussin, J. Andre, M. Devonec, M. Benahmed, and C. Mauduit Activation of caspase-3, -6, and -9 during finasteride treatment of Benig Prostatic Hyperplasia Journal of Clinical Endocrinoly & Metabolism 90 2005 17 25 (Pubitemid 40116628)
15. M.A. Chagas, M.A. Babinski, W.S. Costa, and F.J.B. Sampaio Stromal and acinar components of the transition zone in normal and hyperplastic human prostate British Journal of Urology International 89 2002 699 702 (Pubitemid 34429534)
16. G. Chevalier, P. Benard, H. Cousse, and T. Bengone Distribution study of radioactivity in rats after oral administration of the lipido/sterolic extract of Serenoa repens (Permixon(R)) supplemented with [1-C-14]-lauric acid, [1-C-14]-oleic acid or [4-C-14]-β-sitosterol European Journal of Drug Metabolism and Pharmacokinetics 22 1997 73 83 (Pubitemid 27254327)
17. K. Cho, X. Wang, S. Nie, Z.G. Chen, and D.M. Shin Therapeutic nanoparticles for drug delivery in cancer Clinical Cancer Research 14 2008 1310 1316 (Pubitemid 351413909)
18. G.M. Clifford, and R.D. Farmer Medical therapy for Benign Prostatic Hyperplasia: a review of the literature European Urology 38 2000 2 19 (Pubitemid 30418009)
19. De Bernardi, M. Di Valserra, and A.S. Tripode Rectal bioavailability and pharmacokinetics in healthy volunteers of Serenoa repens new formulation Archives of Internal Medicine 46 1994 7 86
20. C.T. Desphpande, N.H. Rhodes, and Shah Drug Development and Industrial Pharmacy 22 1996 531
21. J. Donnez, P. Smoes, S. Gillerot, F. Casanas-Roux, and M. Nisolle Vascular endothelial growth factor in endometriosis Human Reproduction 13 1998 1686 1690 (Pubitemid 28310515)
22. S. Garcia, H. Heizein, C. Hubbuch, R. Martínez, X. De Vries, and P. Moyna Triterpene methyl ethers from palmae epicuticular waxes Phytochemistry 39 1995 1381 1382
23. Y. Gavrieli, Y. Sherman, and S.A. Ben-Sasson Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation The Journal of Cell Biology 119 1992 493 501
24. G.S. Gerber Saw palmetto for the treatment of men with lower urinary tract symptoms The Journal of Urology 163 2000 1408 1412 (Pubitemid 30226284)
25. G.S. Gerber, and J.M. Fitzpatrick The role of a lipidosterolic extract of Serenoa repens in the management of lower urinary tract symptoms associated with Benign Prostatic Hyperplasia British Journal of Urology International 94 2004 338 344 (Pubitemid 39120176)
26. W.H. Goldmann, A.L. Sharma, S.J. Currier, P.D. Johnston, A. Rana, and C.P. Sharma Saw palmetto berry extract inhibits cell growth and Cox-2 expression in prostatic cancer cells Cell Biology International 25 2001 1117 1124 (Pubitemid 33131829)
27. E.M. Gong, and G.S. Gerber Saw palmetto and Benign Prostatic Hyperplasia The American Journal of Chinese Medicine 32 2004 331 338 (Pubitemid 39089159)
28. R. Hanka Intestinal absorption of polyvinylpyrrolidone Nihon University Journal of Medicine 13 1971 129 146
29. B. Huppertz, H.G. Frank, and P. Kaufmann The apoptosis cascade: morphological and immunohistochemical methods for its visualization Anatomy and Embryology (Berl) 200 1999 1 18 (Pubitemid 29261621)
30. I.B.J.K. Joseph, J.B. Nelson, S.R. Denmeade, and J.T. Isaacs Androgens regulate vascular endothelial growth factor content in normal and malignant prostatic tissue Clinical Cancer Research 3 1997 2507 2511 (Pubitemid 28133175)
31. A. Kassen, D.M. Sutkowski, H. Ahn, J.A. Sensibar, J.M. Kozlowski, and C. Lee Stromal cells of the human prostate: initial isolation and characterization The Prostate 28 1996 89 97 (Pubitemid 26066246)
32. E. Koch Extracts from fruits of saw palmetto (Sabal serrulata) and roots of stinging nettle (Urtica dioica): viable alternatives in the medical treatment of Benign Prostatic Hyperplasia and associated lower urinary tracts symptoms Planta Medica 67 2001 489 500 (Pubitemid 32800412)
33. D. Lorke A new approach to practical acute toxicity testing Archives of Toxicology 54 1983 275 287 (Pubitemid 14205493)
34. F.C. Lowe, and E. Fagelman Phytotherapy in the treatment of Benign Prostatic Hyperplasia Current Opinion in Urology 12 2002 15 18 (Pubitemid 34033063)
35. J.E. McNeal Pathology of Benign Prostatic Hyperplasia: insight into etiology Urologic Clinics of North America 17 1990 477 486
36. K.T. McVary BPH: epidemiology and comorbidities American Journal of Managed Care 12 2006 S122 S128
37. M.B.S. Maia, and V.S. Rao Anti-inflammatory activity of Orbignya phalerata in rats Phytotherapy Research 3 1989 170 174 (Pubitemid 19262272)
38. L.S. Marks, A.W. Partin, J.I. Epstein, V.E. Tyler, I. Simon, M.L. Macairan, T.L. Chan, F.J. Dorey, J.B. Garris, R.W. Veltri, P.B.C. Santos, K.A. Stonebrook, and J.B. de Kernion Effects of a saw palmetto herbal blend in men with symptomatic Benign Prostatic Hyperplasia The Journal of Urology 163 2000 1451 1456 (Pubitemid 30226294)
39. J.E. Oesterling Benign Prostatic Hyperplasia. Medical and minimally invasive treatment options The New England Journal of Medicine 332 1995 99 109
40. G. Pareek, M. Shevchuk, N.A. Armenakas, L. Vasjovic, D.A. Hochberg, J.B. Basillote, and J.A. Fracchia The effect of finasteride on the expression of vascular endothelial growth factor and microvessel density: a possible mechanism for decreased prostatic bleeding in treated patients The Journal of Urology 169 2003 20 23 (Pubitemid 35461539)
41. M.T. Quiles, M.A. Arbós, A. Fraga, I.M. de Torres, J. Reventós, and J. Morote Antiproliferative and apoptotic effects of the herbal agent Pygeum africanum on cultured prostate stromal cells from patients with Benig Prostatic Hyperplasia (BPH) The Prostate 70 2010 1044 1053
42. M.N. Rennó, G.M. Barbosa, P. Zancan, V.F. Veiga, C.S. Alviano, M. Sola-Penna, F.S. Menezes, and C. Holandino Crude ethanol extract from babassu (Orbignya speciosa): cytotoxicity on tumoral and non-tumoral cell lines Anais da Academia Brasileira de Ciências 80 2008 467 476
43. I.G. Schauer, S.J. Ressler, and D.R. Rowley Keratinocyte-derived chemokine induces prostate epithelial hyperplasia and reactive stroma in a novel transgenic mouse model The Prostate 69 2009 373 384
44. I.G. Schauer, S.J. Ressler, J.A. Tuxhorn, T.D. Dang, and D.R. Rowley Elevated epithelial expression of interleukin-8 correlates with myofibroblast reactive stroma in Benign Prostatic Hyperplasia Urology 72 2008 205 213
45. B.P. Silva, and J.P. Parente An anti-inflammatory and immonomodulatory polysaccharide from Orbignya phalerata Fitoterapia 72 2001 887 893
46. A. Tiwari, N.S. Krishna, K. Nanda, and A. Chugh Benign Prostatic Hyperplasia: an insight into current investigational medical therapies Expert Opinion on Investigational Drugs 14 2005 1359 1372 (Pubitemid 41601452)
47. R. Vela-Navarrete, M. Escribano-Burgos, A.L. Farré, J. García-Cardoso, F. Manzarbeitia, and C. Carrasco Serenoa repens treatment modifies bax/bcl-2 index expression and caspase-3 activity in prostatic tissue from patients with Benign Prostatic Hyperplasia The Journal of Urology 173 2005 507 510
48. T.L. Wadsworth, J.M. Carroll, R.A. Mallinson, C.T. Roberts Jr., and C.E. Roselli Saw palmetto extract suppresses insulin-like growth factor-I signaling and induces stress-activated protein kinase/c-Jun N-terminal kinase phosphorylation in human prostate epithelial cells Endocrinology 145 2004 3205 3214 (Pubitemid 38829992)
49. T.J. Wilt, A. Ishani, G. Stark, R. MacDonald, J. Lau, and C. Mulrow Saw palmetto extracts for treatment of Benign Prostatic Hyperplasia The Journal of the American Medical Association 280 1998 1604 1609 (Pubitemid 28520650)