The Interplay of ClpXP with the cell division machinery in Escherichia coli

Journal of Bacteriology

Volumn 193, Issue 8, 2011, Pages 1911-1918

  Camberg, Jodi L ^a   Hoskins, Joel R ^a   Wickner, Sue ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLPXP PROTEIN; FTSZ PROTEIN; PROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; CELL DIVISION; ESCHERICHIA COLI; GENE DELETION; GENE MUTATION; IMMUNOFLUORESCENCE; MICROSCOPY; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING;

ADENOSINE TRIPHOSPHATASES; BACTERIAL PROTEINS; CELL DIVISION; CYTOSKELETAL PROTEINS; ENDOPEPTIDASE CLP; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE DELETION; MEMBRANE PROTEINS; MICROSCOPY; MOLECULAR CHAPERONES;

ESCHERICHIA COLI;

EID: 79955460424     PISSN: 00219193     EISSN: 10985530     Source Type: Journal    
DOI: 10.1128/JB.01317-10     Document Type: Article

References (40)

1. Adams, D. W., and J. Errington. 2009. Bacterial cell division: assembly, maintenance and disassembly of the Z ring. Nat. Rev. Microbiol. 7:642-653.
2. Akerlund, T., R. Bernander, and K. Nordstrom. 1992. Cell division in Escherichia coli minB mutants. Mol. Microbiol. 6:2073-2083.
3. Akerlund, T., K. Nordstrom, and R. Bernander. 1993. Branched Escherichia coli cells. Mol. Microbiol. 10:849-858.
4. Anderson, D. E., F. J. Gueiros-Filho, and H. P. Erickson. 2004. Assembly dynamics of FtsZ rings in Bacillus subtilis and Escherichia coli and effects of FtsZ-regulating proteins. J. Bacteriol. 186:5775-5781.
5. Baba, T., et al. 2006. Construction of Escherichia coli K-12 in-frame, singlegene knockout mutants: the Keio collection. Mol. Syst. Biol. 2:2006.0008.
6. Bendezu, F. O., and P. A. de Boer. 2008. Conditional lethality, division defects, membrane involution, and endocytosis in mre and mrd shape mutants of Escherichia coli. J. Bacteriol. 190:1792-1811.
7. Bernhardt, T. G., and P. A. de Boer. 2004. Screening for synthetic lethal mutants in Escherichia coli and identification of EnvC (YibP) as a periplasmic septal ring factor with murein hydrolase activity. Mol. Microbiol. 52: 1255-1269.
8. Bernhardt, T. G., and P. A. de Boer. 2005. SlmA, a nucleoid-associated, FtsZ binding protein required for blocking septal ring assembly over chromosomes in E. coli. Mol. Cell 18:555-564.
9. Bi, E., and J. Lutkenhaus. 1990. Analysis of ftsZ mutations that confer resistance to the cell division inhibitor SulA (SfiA). J. Bacteriol. 172:5602-5609.
10. Blattner, F. R., et al. 1997. The complete genome sequence of Escherichia coli K-12. Science 277:1453-1462.
11. Camberg, J. L., J. R. Hoskins, and S. Wickner. 2009. ClpXP protease degrades the cytoskeletal protein, FtsZ, and modulates FtsZ polymer dynamics. Proc. Natl. Acad. Sci. U. S. A. 106:10614-10619.
12. Chen, Y., and H. P. Erickson. 2005. Rapid in vitro assembly dynamics and subunit turnover of FtsZ demonstrated by fluorescence resonance energy transfer. J. Biol. Chem. 280:22549-22554.
13. Cherepanov, P. P., and W. Wackernagel. 1995. Gene disruption in Escherichia coli: TcR and KmR cassettes with the option of Flp-catalyzed excision of the antibiotic-resistance determinant. Gene 158:9-14.
14. Dai, K., and J. Lutkenhaus. 1992. The proper ratio of FtsZ to FtsA is required for cell division to occur in Escherichia coli. J. Bacteriol. 174:6145-6151.
15. Dai, K., Y. Xu, and J. Lutkenhaus. 1993. Cloning and characterization of ftsN, an essential cell division gene in Escherichia coli isolated as a multicopy suppressor of ftsA12(Ts). J. Bacteriol. 175:3790-3797.
16. Dajkovic, A., G. Lan, S. X. Sun, D. Wirtz, and J. Lutkenhaus. 2008. MinC spatially controls bacterial cytokinesis by antagonizing the scaffolding function of FtsZ. Curr. Biol. 18:235-244.
17. de Boer, P. A., R. E. Crossley, and L. I. Rothfield. 1989. A division inhibitor and a topological specificity factor coded for by the minicell locus determine proper placement of the division septum in E. coli. Cell 56:641-649.
18. Dziedzic, R., et al. 2010. Mycobacterium tuberculosis ClpX interacts with FtsZ and interferes with FtsZ assembly. PLoS One 5:e11058.
19. Flynn, J. M., S. B. Neher, Y. I. Kim, R. T. Sauer, and T. A. Baker. 2003. Proteomic discovery of cellular substrates of the ClpXP protease reveals five classes of ClpX-recognition signals. Mol. Cell 11:671-683.
20. Gottesman, S., W. P. Clark, V. de Crecy-Lagard, and M. R. Maurizi. 1993. ClpX, an alternative subunit for the ATP-dependent Clp protease of Escherichia coli. Sequence and in vivo activities. J. Biol. Chem. 268:22618-22626.
21. BAD promoter. J. Bacteriol. 177:4121-4130.
22. Haeusser, D. P., A. H. Lee, R. B. Weart, and P. A. Levin. 2009. ClpX inhibits FtsZ assembly in a manner that does not require its ATP hydrolysis-dependent chaperone activity. J. Bacteriol. 191:1986-1991.
23. Hersch, G. L., R. E. Burton, D. N. Bolon, T. A. Baker, and R. T. Sauer. 2005. Asymmetric interactions of ATP with the AAA+ ClpX6 unfoldase: allosteric control of a protein machine. Cell 121:1017-1027.
24. Hoskins, J. R., S. K. Singh, M. R. Maurizi, and S. Wickner. 2000. Protein binding and unfolding by the chaperone ClpA and degradation by the protease ClpAP. Proc. Natl. Acad. Sci. U. S. A. 97:8892-8897.
25. Hu, Z., and J. Lutkenhaus. 2001. Topological regulation of cell division in E. coli. Spatiotemporal oscillation of MinD requires stimulation of its ATPase by MinE and phospholipid. Mol. Cell 7:1337-1343.
26. Ivanov, V., and K. Mizuuchi. 2010. Multiple modes of interconverting dynamic pattern formation by bacterial cell division proteins. Proc. Natl. Acad. Sci. U. S. A. 107:8071-8078.
27. Li, Z., M. J. Trimble, Y. V. Brun, and G. J. Jensen. 2007. The structure of FtsZ filaments in vivo suggests a force-generating role in cell division. EMBO J. 26:4694-4708.
28. Lutkenhaus, J. 2007. Assembly dynamics of the bacterial MinCDE system and spatial regulation of the Z ring. Annu. Rev. Biochem. 76:539-562.
29. Meinhardt, H., and P. A. de Boer. 2001. Pattern formation in Escherichiacoli: a model for the pole-to-pole oscillations of Min proteins and the localization of the division site. Proc. Natl. Acad. Sci. U. S. A. 98:14202-14207.
30. Neher, S. B., et al. 2006. Proteomic profiling of ClpXP substrates after DNA damage reveals extensive instability within SOS regulon. Mol. Cell 22:193-204.
31. Roll-Mecak, A., and R. D. Vale. 2008. Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin. Nature 451:363-367.
32. Sauer, R. T., et al. 2004. Sculpting the proteome with AAA(+) proteases and disassembly machines. Cell 119:9-18.
33. Shorter, J., and S. Lindquist. 2004. Hsp104 catalyzes formation and elimination of self-replicating Sup35 prion conformers. Science 304:1793-1797.
34. Sugimoto, S., et al. 2010. AAA+ chaperone ClpX regulates dynamics of prokaryotic cytoskeletal protein FtsZ. J. Biol. Chem. 285:6648-6657.
35. Tonthat, N. K., et al. 2011. Molecular mechanism by which the nucleoid occlusion factor, SlmA, keeps cytokinesis in check. EMBO J. 30:154-164.
36. Wang, X. D., P. A. de Boer, and L. I. Rothfield. 1991. A factor that positively regulates cell division by activating transcription of the major cluster of essential cell division genes of Escherichia coli. EMBO J. 10:3363-3372.
37. Weart, R. B., and P. A. Levin. 2003. Growth rate-dependent regulation of medial FtsZ ring formation. J. Bacteriol. 185:2826-2834.
38. Weart, R. B., S. Nakano, B. E. Lane, P. Zuber, and P. A. Levin. 2005. The ClpX chaperone modulates assembly of the tubulin-like protein FtsZ. Mol. Microbiol. 57:238-249.
39. Yu, X. C., and W. Margolin. 2000. Deletion of the min operon results in increased thermosensitivity of an ftsZ84 mutant and abnormal FtsZ ring assembly, placement, and disassembly. J. Bacteriol. 182:6203-6213.
40. Yu, X. C., and W. Margolin. 1999. FtsZ ring clusters in min and partition mutants: role of both the Min system and the nucleoid in regulating FtsZ ring localization. Mol. Microbiol. 32:315-326.