Androgens modulate structure and function of the suprachiasmatic nucleus brain clock

Endocrinology

Volumn 152, Issue 5, 2011, Pages 1970-1978

  Karatsoreos, Ilia N ^a   Butler, Matthew P ^a   Lesauter, Joseph ^b   Silver, Rae ^a,b,c  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b Barnard College of Columbia University   (United States)

^c NewYork Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; BOLDENONE; GLIAL FIBRILLARY ACIDIC PROTEIN; SYNAPTOPHYSIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CIRCADIAN RHYTHM; CONTROLLED STUDY; GONADECTOMY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LIGHT ADAPTATION; MALE; MOUSE; NERVE CELL MEMBRANE POTENTIAL; NERVE CELL PLASTICITY; NONHUMAN; POSTSYNAPTIC DENSITY; PRIORITY JOURNAL; SUPRACHIASMATIC NUCLEUS; WESTERN BLOTTING;

ANDROGENS; ANIMALS; BIOLOGICAL CLOCKS; BLOTTING, WESTERN; BRAIN; CIRCADIAN RHYTHM; DIHYDROTESTOSTERONE; GENE EXPRESSION; GLIAL FIBRILLARY ACIDIC PROTEIN; IN SITU HYBRIDIZATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGHT; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; MOTOR ACTIVITY; ORCHIECTOMY; PERIOD CIRCADIAN PROTEINS; SUPRACHIASMATIC NUCLEUS; SYNAPTOPHYSIN; TIME FACTORS;

EID: 79955456568     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2010-1398     Document Type: Article

References (64)

1. Dibner C, Schibler U, Albrecht U 2010 The mammalian circadian timing system: organization and coordinationof central and peripheral clocks. Annu Rev Physiol 72:517-549
2. Butler MP, Kriegsfeld LJ, Silver R 2009 Circadian regulation of endocrine functions. In: Pfaff D, Arnold A, Etgen A, Fahrbach S, Rubin R, eds. Hormones, brain and behavior. 2nd ed. San Diego: Academic Press; 473-505
3. Yan L, Karatsoreos IN, Le Sauter J, Welsh DK, Kay S, Foley DK, Silver R 2007 Exploring spatiotemporal organization of SCN circuits. Cold Spring Harb Symp Quant Biol 72:527-541
4. Welsh DK, Takahashi JS, Kay SA 2010 Suprachiasmatic nucleus: cell autonomy and network properties. Annu Rev Physiol 72:551-577
5. Karatsoreos IN, Wang A, Sasanian J, Silver R 2007 A role for androgens in regulating circadian behavior and the suprachiasmatic nucleus. Endocrinology 148:5487-5495 (Pubitemid 350012648)
6. Zhou L, Blaustein JD, De Vries GJ 1994 Distribution of androgen receptor immunoreactivity in vasopressin-and oxytocin-immunoreactive neurons in the male rat brain. Endocrinology 134:2622-2627 (Pubitemid 24170879)
7. Fernandez-Guasti A, Kruijver FP, Fodor M, Swaab DF 2000 Sex differences in the distribution of androgen receptors in the human hypothalamus. J Comp Neurol 425:422-435 (Pubitemid 30659207)
8. Kashon ML, Arbogast JA, Sisk CL 1996 Distribution and hormonal regulation of androgen receptor immunoreactivity in the forebrain of the male European ferret. J Comp Neurol 376:567-586 (Pubitemid 27009841)
9. Abrahamson EE, Moore RY 2001 Suprachiasmatic nucleus in the mouse: retinal innervation, intrinsic organization and efferent projections. Brain Res 916:172-191 (Pubitemid 32971919)
10. Antle MC, Silver R 2005 Orchestrating time: arrangements of the brain circadian clock. Trends Neurosci 28:145-151 (Pubitemid 40320760)
11. Daan S, Damassa D, Pittendrigh CS, Smith ER 1975 An effect of castration and testosterone replacement on a circadian pacemaker in mice (Mus musculus). Proc Natl Acad Sci USA 72:3744-3747
12. McEwen BS, Coirini H, Westlind-Danielsson A, Frankfurt M, Gould E, Schumacher M, Woolley C 1991 Steroid hormones as mediators of neural plasticity. J Steroid Biochem Mol Biol 39:223-232
13. Lindzey J, Wetsel WC, Couse JF, Stoker T, Cooper R, Korach KS 1998 Effects of castration and chronic steroid treatments on hypothalamic gonadotropin-releasing hormone content and pituitary gonadotropins in male wild-type and estrogen receptor-α knockout mice. Endocrinology 139:4092-4101 (Pubitemid 28513693)
14. Rieux C, Carney R, Lupi D, Dkhissi-Benyahya O, Jansen K, Chounlamountri N, Foster RG, Cooper HM 2002 Analysis of immunohistochemical label of Fos protein in the suprachiasmatic nucleus: comparison of different methods of quantification. J Biol Rhythms 17:121-136 (Pubitemid 37187352)
15. Karatsoreos IN, Romeo RD, McEwen BS, Silver R 2006 Diurnal regulation of the gastrin-releasing peptide receptor in the mouse circadian clock. Eur J Neurosci 23:1047-1053 (Pubitemid 43344699)
16. Yan L, Silver R 2002 Differential induction and localization of mPer1 and mPer2 during advancing and delaying phase shifts. Eur J Neurosci 16:1531-1540 (Pubitemid 35334990)
17. Romeo RD, Karatsoreos IN, Jasnow AM, McEwen BS 2007 Ageand stress-induced changes in corticotropin-releasing hormone mRNA expression in the paraventricular nucleus of the hypothalamus. Neuroendocrinology 85:199-206 (Pubitemid 47123454)
18. Antle MC, Kriegsfeld LJ, Silver R 2005 Signaling within the master clock of the brain: localized activation of mitogen-activated protein kinase by gastrin-releasing peptide. J Neurosci 25:2447-2454 (Pubitemid 40365154)
19. Van den Pol AN 1980 The hypothalamic suprachiasmatic nucleus of rat: intrinsic anatomy. J Comp Neurol 191:661-702
20. Oliet SH, Piet R, Poulain DA, Theodosis DT 2004 Glial modulation of synaptic transmission: insights from the supraoptic nucleus of the hypothalamus. Glia 47:258-267 (Pubitemid 39121071)
21. Melcangi RC, Riva MA, Fumagalli F, Magnaghi V, Racagni G, Martini L 1996 Effect of progesterone, testosterone and their 5α-reduced metabolites on GFAP gene expression in type 1 astrocytes. Brain Res 711:10-15 (Pubitemid 26081840)
22. Day JR, Laping NJ, McNeill TH, Schreiber SS, Pasinetti G, Finch CE 1990 Castration enhances expression of glial fibrillary acidic protein and sulfated glycoprotein-2 in the intact and lesion-altered hippocampus of the adult male rat. Mol Endocrinol 4:1995-2002
23. Butz M, Wörgötter F, van Ooyen A 2009 Activity-dependent structural plasticity. Brain Res Rev 60:287-305
24. Pendergast JS, Friday RC, Yamazaki S 2010 Photic entrainment of period mutant mice is predicted from their phase response curves. J Neurosci 30:12179-12184
25. Butler MP, Silver R 2009 Basis of robustness and resilience in the suprachiasmatic nucleus: individual neurons form nodes in circuits that cycle daily. J Biol Rhythms 24:340-352
26. Miche S, Colwell CS 2001 Cellular communication and coupling within the suprachiasmatic nucleus. Chronobiol Int 18:579-600 (Pubitemid 32929206)
27. Theodosis DT, Poulain DA, Oliet SH 2008 Activity-dependent structural and functional plasticityofastrocyte-neuron interactions. Physiol Rev 88:983-1008
28. Newman EA 2003 New roles for astrocytes: regulation of synaptic transmission. Trends Neurosci 26:536-542 (Pubitemid 37176908)
29. Servière J, Lavialle M 1996 Astrocytes in the mammalian circadian clock: putative roles. Prog Brain Res 111:57-73 (Pubitemid 26421011)
30. van den Pol AN, Finkbeiner SM, Cornell-Bell AH 1992 Calcium excitability and oscillationsin suprachiasmatic nucleus neurons and glia in vitro. J Neurosci 12:2648-2664
31. Shinohara K, Honma S, Katsuno Y, Abe H, Honma K 1995 Two distinct oscillators in the rat suprachiasmatic nucleus in vitro. Proc Natl Acad Sci USA 92:7396-7400
32. Shinohara K, Funabashi T, Mitushima D, Kimura F 2000 Effects of gap junction blocker on vasopressin and vasoactive intestinal polypeptide rhythms in the rat suprachiasmatic nucleus in vitro. Neurosci Res 38:43-47
33. Hösli E, Hösli L 1993 Receptors for neurotransmitters onastrocytes in the mammalian central nervous system. Prog Neurobiol 40:477-506 (Pubitemid 23031368)
34. Lavialle M, Begue A, Papillon C, Vilaplana J 2001 Modifications of retinal afferent activity induce changes in astroglial plasticity in the hamster circadian clock. Glia 34:88-100 (Pubitemid 32480588)
35. Girardet C, Blanchard MP, Ferracci G, Lévêque C, Moreno M, François-Bellan AM, Becquet D, Bosler O 2010 Daily changes in synaptic innervation of VIP neurons in the rat suprachiasmatic nucleus: contribution of glutamatergic afferents. Eur J Neurosci 31:359-370
36. Lu B, Chow A 1999 Neurotrophins and hippocampal synaptic transmission and plasticity. J Neurosci Res 58:76-87 (Pubitemid 29463694)
37. Keith D, El-Husseini A 2008 Excitation control: balancing PSD-95 function at the synapse. Front Mol Neurosci 1:4
38. Hajszan T, MacLusky NJ, Johansen JA, Jordan CL, Leranth C 2007 Effects of androgens and estradiol on spine synapse formation in the prefrontal cortex of normal and testicular feminization mutant male rats. Endocrinology 148:1963-1967 (Pubitemid 46997025)
39. Leranth C, Hajszan T, MacLusky NJ 2004 Androgens increase spine synapse density in the CA1 hippocampal subfield of ovariectomized female rats. J Neurosci 24:495-499 (Pubitemid 38112381)
40. MacLusky NJ, Hajszan T, Leranth C 2004 Effects of dehydroepiandrosterone and flutamide on hippocampal CA1 spine synapse density in male and female rats: implications for the role of androgens in maintenance of hippocampal structure. Endocrinology 145:4154-4161 (Pubitemid 39120564)
41. MacLusky NJ, Hajszan T, Johansen JA, Jordan CL, Leranth C 2006 Androgen effects on hippocampal CA1 spine synapse numbers are retained in Tfm male rats with defective androgen receptors. Endocrinology 147:2392-2398
42. Kurz EM, Sengelaub DR, Arnold AP 1986 Androgens regulate the dendritic length of mammalian motoneurons in adulthood. Science 232:395-398 (Pubitemid 16047593)
43. Herzog ED, Aton SJ, Numano R, Sakaki Y, Tei H 2004 Temporal precision in the mammalian circadian system: a reliable clock from less reliable neurons. J Biol Rhythms 19:35-46 (Pubitemid 38084513)
44. Achermann P, Kunz H 1999 Modeling circadian rhythm generation in the suprachiasmatic nucleus with locally coupled self-sustained oscillators: phase shifts and phase response curves. J Biol Rhythms 14:460-468 (Pubitemid 30086853)
45. Akiyama M, Kouzu Y, Takahashi S, Wakamatsu H, Moriya T, Maetani M, Watanabe S, Tei H, Sakaki Y, Shibata S 1999 Inhibition of light-or glutamate-induced mPer1 expression represses the phase shifts into the mouse circadian locomotor and suprachiasmatic firing rhythms. J Neurosci 19:1115-1121 (Pubitemid 29066172)
46. Shigeyoshi Y, Taguchi K, Yamamoto S, Takekida S, Yan L, Tei H, Moriya T, Shibata S, Loros JJ, Dunlap JC, Okamura H 1997 Lightinduced resetting of a mammalian circadian clock is associated with rapid induction of the mPer1 transcript. Cell 91:1043-1053 (Pubitemid 28027836)
47. Hannibal J, Jamen F, Nielsen HS, Journot L, Brabet P, Fahrenkrug J 2001 Dissociation between light-induced phase shift of the circadian rhythm and clock gene expression in mice lacking the pituitary adenylate cyclase activating polypeptide type 1 receptor. J Neurosci 21:4883-4890 (Pubitemid 32565646)
48. Morin LP 1980 Effect of ovarian hormones on synchrony of hamster circadian rhythms. Physiol Behav 24:741-749 (Pubitemid 10058467)
49. Morin LP, Cummings la 1981 Effect of surgical or photoperiodic castration, testosterone replacement or pinealectomy on male hamster running rhythmicity. Physiol Behav 26:825-838 (Pubitemid 11048814)
50. Morin LP, Fitzgerald KM, Zucker I 1977 Estradiol shortens the period of hamster circadian rhythms. Science 196:305-307 (Pubitemid 8076956)
51. Jechura TJ, Walsh JM, Lee TM 2000 Testicular hormones modulate circadian rhythms of the diurnal rodent, Octodon degus. Horm Behav 38:243-249
52. Jechura TJ, Walsh JM, Lee TM 2003 Testosterone suppresses circadian responsiveness to social cues in the diurnal rodent Octodon degus. J Biol Rhythms 18:43-50 (Pubitemid 37187306)
53. Lee TM, Hummer DL, Jechura TJ, Mahoney MM 2004 Pubertal development of sex differences in circadian function: an animal model. Ann NY Acad Sci 1021:262-275 (Pubitemid 38879632)
54. Hummer DL, Jechura TJ, Mahoney MM, Lee TM 2007 Gonadal hormone effects on entrained and free-running circadian activity rhythms in the developing diurnal rodent Octodon degus. Am J Physiol Regul Integr Comp Physiol 292: R586-R597 (Pubitemid 46089875)
55. Vida B, Hrabovszky E, Kalamatianos T, Coen CW, Liposits Z, Kallo I 2008 Oestrogen receptor α and β immunoreactive cells in the suprachiasmatic nucleus of mice: distribution, sex differences and regulation by gonadal hormones. J Neuroendocrinol 20:1270-1277
56. Pak TR, Chung WC, Hinds LR, Handa RJ 2009 Arginine vasopressin regulation in pre-and postpubertal male rats by the androgen metabolite 3β-diol. Am J Physiol Endocrinol Metab 296: E1409-E1413
57. Foradori CD, Weiser MJ, Handa RJ 2008 Non-genomic actions of androgens. Front Neuroendocrinol 29:169-181
58. Iwahana E, Karatsoreos I, Shibata S, Silver R 2008 Gonadectomy reveals sex differences in circadian rhythms and suprachiasmatic nucleus androgen receptors in mice. Horm Behav 53:422-430
59. Paul KN, Dugovic C, Turek FW, Laposky AD 2006 Diurnal sex differences in the sleep-wake cycle of mice are dependent on gonadal function. Sleep 29:1211-1223 (Pubitemid 44484815)
60. Wever RA 1984 Sex differences in human circadian rhythms: intrinsic periods and sleep fractions. Experientia 40:1226-1234 (Pubitemid 15077837)
61. Empson JA, Purdie DW 1999 Effects of sex steroids on sleep. Ann Med 31:141-145 (Pubitemid 29209870)
62. Paul KN, Turek FW, Kryger MH 2008 Influence of sex on sleep regulatory mechanisms. J Womens Health 17:1201-1208
63. Roenneberg T, Kuehnle T, Pramstaller PP, Ricken J, Havel M, Guth A, Merrow M 2004 A marker for the end of adolescence. Curr Biol 14: R1038-R1039 (Pubitemid 40033344)
64. Karatsoreos IN, Silver R 2007 Minireview: the neuroendocrinology of the suprachiasmatic nucleus as a conductor of body time in mammals. Endocrinology 148:5640-5647 (Pubitemid 350146136)