Effects of Acute Hepatic and Renal Failure on Pharmacokinetics of Flunixin Meglumine in Rats

Experimental Animals

Volumn 60, Issue 2, 2011, Pages 187-191

  Hwang, Youn Hwan ^a   Yun, Hyo In ^a  

^a Chungnam National University   (South Korea)

Author keywords

Acute renal and hepatic failure; Flunixin; Pharmacokinetics

Indexed keywords

FLUNIXIN MEGLUMINE; FLUXIMINE; UNCLASSIFIED DRUG;

ACUTE KIDNEY FAILURE; ACUTE LIVER FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG ELIMINATION; DRUG HALF LIFE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MEAN RESIDENCE TIME; NONHUMAN; NOTE; PLASMA CONCENTRATION-TIME CURVE; RAT;

ACUTE KIDNEY INJURY; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARBON TETRACHLORIDE; CLONIXIN; GLYCEROL; LIVER FAILURE, ACUTE; MALE; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 79955433104     PISSN: 13411357     EISSN: None     Source Type: Journal    
DOI: 10.1538/expanim.60.187     Document Type: Note

References (31)

1. Baert, K. and De Backer, P. 2002. J. Vet. Pharmacol. Ther. 25: 449-453.
2. Buur, J.L., Baynes, R.E., Smith, G., and Riviere, J.E. 2006. J. Vet. Pharmacol. Ther. 29: 437-440.
3. Cheng, Z., McKeller, Q., and Nolan, A. 1998. J. Vet. Pharmacol. Ther. 21: 315-321.
4. CVMP. 1999. Flunixin, Summary report, EMEA/MRL/661/99-FINAL European Medicines Agency, UK.
5. Elmas, M., Uney, K., Karabacak, A., and Yazar, E. 2005. Bull. Vet. Inst. Pulawy 49: 85-88.
6. Elmas, M., Yazar, E., Uney, K., and Karabacak, A. 2006. Vet. Res. Commun. 30: 73-81.
7. Galbraith, E.A. and McKellar, Q.A. 1996. Res. Vet. Sci. 61: 78-81.
8. Geier, A., Kim, S.K., Gerloff, T., Dietrich, C.G., Lammert, F., Karpen, S.J., Stieger, B., Meier, P.J., Matern, S., and Gartung, C. 2002. J. Hepatol. 37: 198-205.
9. Horii, Y., Ikenaga, M., Shimoda, M., and Kokue, E. 2004. J. Vet. Pharmacol. Ther. 27: 65-69.
10. Jiko, M., Yano, I., Okuda, M., and Inui, K. 2005. Pharm. Res. 22: 228-234.
11. Johnson, C.B., Taylor, P.M., Young, S.S., and Brearley, J.C. 1993. Vet. Rec. 133: 336-338.
12. Konigsson, K., Torneke, K., Engeland, I.V., Odensvik, K., and Kindahl, H. 2003. Acta Vet. Scand. 44: 153-159.
13. Konishi, H., Sudo, M., Sumi, M., Morii, H., Minouchi, T., Aimoto, T., and Yamaji, A. 2005. Biol. Pharm. Bull. 28: 556-559.
14. Lascelles, B.D., Court, M.H., Hardie, E.M., and Robertson, S.A. 2007. Vet. Anaesth. Analg. 34: 228-250.
15. MacAllister, C.G., Morgan, S.J., Borne, A.T., and Pollet, R.A. 1993. J. Am. Vet. Med. Assoc. 202: 71-77.
16. Miyazaki, Y., Horii, Y., Ikenaga, N., Shimoda, M., and Kokue, E. 2001. J. Vet. Med. Sci. 63: 885-888.
17. Naud, J., Michaud, J., Leblond, F.A., Lefrancois, S., Bonnardeaux, A., and Pichette, V. 2008 Drug Metab. Dispos. 36: 124-128.
18. Pellegrini-Masini, A., Poppenga, R.H., and Sweeney, R.W. 2004. J. Vet. Pharmacol. Ther. 27: 183-186.
19. Ogino, T. and Arai, T. 2007. Exp. Anim. 56: 79-84.
20. Ogino, T., Mizuno, Y., Ogata, T., and Takahashi, Y. 2005. Am. J. Vet. Res. 66: 1209-1213.
21. Okumura, H., Katoh, M., Minami, K., Nakajima, M., and Yokoi, T. 2007. Biochem. Pharmacol. 74: 488-495.
22. Peek, S.F., Semrad, S.D., and Perkins, G.A. 2003. Equine Vet. J. 35: 86-92.
23. Rantala, M., Kaartinen, L., Valimaki, E., Stryrman, M., Hiekkaranta, M., Niemi, A., Saari, L., and Pyorala, S. 2002. J. Vet. Pharmacol. Ther. 25: 251-258.
24. Safarchi, R., Mozaffari, A.A., Derakhshanfar, A., and Amiri Marvili, O. 2010. J. Biol. Sci. 10: 170-173.
25. Soma, L.R., Behrend, E., Rudy, J., and Sweeney, R.W. 1988. Am. J. Vet. Res. 49: 1894-1898.
26. Stegelmeier, B.L., Bottoms, G.D., Denicola, D.B., and Reed, W.M. 1988. Cornell Vet. 78: 221-230.
27. Sun, H., Frassetto, L., and Benet, L.Z. 2006. Pharmacol. Ther. 109: 1-11.
28. Taylor, P.M., Lees, P., Reynoldson, J., Stodulski, G., and Jefferies, R. 1991. Vet. Rec. 128: 258.
29. Taylor, P.M., Winnard, J.G., Jefferies, R., and Lees, P. 1994. Br. Vet. J. 150: 253-262.
30. Yamaoka, K., Nakagawa, T., and Uno, T. 1978. J. Pharmacokinet. Biopharm. 6: 165-175.
31. Yazar, E., Er, A., Uney, K., Altunok, V., and Elmas, M. 2007. J. Vet. Med. A Physiol. Pathol. Clin. Med. 54: 352-355.