Base of the thumb domain modulates epithelial sodium channel gating

Journal of Biological Chemistry

Volumn 286, Issue 17, 2011, Pages 14753-14761

  Shi, Shujie ^a   Dipon Ghosh, D ^b   Okumura, Sora ^a   Carattino, Marcelo D ^a   Kashlan, Ossama B ^a   Sheng, Shaohu ^a,c   Kleyman, Thomas R ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b CARNEGIE MELLON UNIVERSITY   (United States)

^c Renal Electrolyte Division   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID-SENSING ION CHANNELS; CHANNEL GATES; CHANNEL GATING; CHANNEL RESPONSE; CONFORMATIONAL CHANGE; EPITHELIAL SODIUM CHANNELS; EXTERNAL FACTORS; EXTERNAL SIGNALS; EXTERNAL STIMULUS; EXTRACELLULAR REGION; ION CHANNEL; TRANS-MEMBRANE DOMAINS;

ACTIVATION ANALYSIS; CRYSTAL STRUCTURE; CYLINDERS (SHAPES); IONS; SHEAR STRESS; SIGNAL PROCESSING;

ENZYME ACTIVITY;

EPITHELIAL SODIUM CHANNEL; PROTEIN SUBUNIT; SODIUM ION; TYROSINE;

ANIMAL CELL; ARTICLE; CELL MEMBRANE TRANSPORT; CHANNEL GATING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; EXTRACELLULAR SPACE; INHIBITION KINETICS; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SHEAR STRESS; STIMULUS RESPONSE;

ANIMALS; EPITHELIAL SODIUM CHANNEL; ION CHANNEL GATING; MICE; MUTATION; NERVE TISSUE PROTEINS; OOCYTES; PATCH-CLAMP TECHNIQUES; PROTEIN STRUCTURE, TERTIARY; SODIUM; SODIUM CHANNELS; STRESS, MECHANICAL; XENOPUS LAEVIS;

EID: 79955423693     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.191734     Document Type: Article

References (25)

1. Sheng, S., Johnson, J. P., and Kleyman, T. R. (2008) in Epithelial Sodium Channels, The Kidney, Physiology and Pathophysiology (Alpern, R. J., and Hebert, S. C., eds), Fourth Ed., Elsevier Publishing, Philadelphia, PA
2. Kleyman, T. R., Carattino, M. D., and Hughey, R. P. (2009) J. Biol. Chem. 284, 20447-20451
3. Bhalla, V., and Hallows, K. R. (2008) J. Am. Soc. Nephrol 19, 1845-1854
4. Collier, D. M., and Snyder, P. M. (2009) J. Biol. Chem. 284, 792-798
5. Collier, D. M., and Snyder, P. M. (2009) J. Biol. Chem. 284, 29320-29325
6. Carattino, M. D., Sheng, S., and Kleyman, T. R. (2004) J. Biol. Chem. 279, 4120-4126
7. Jasti, J., Furukawa, H., Gonzales, E. B., and Gouaux, E. (2007) Nature 449, 316-323
8. Gonzales, E. B., Kawate, T., and Gouaux, E. (2009) Nature 460, 599-604
9. Kashlan, O. B., Adelman, J. L., Okumura, S., Blobner, B. M., Zuzek, Z., Hughey, R. P., Kleyman, T. R., and Grabe, M. (2011) J. Biol. Chem. 286, 649-660
10. Li, T., Yang, Y., and Canessa, C. M. (2009) J. Biol. Chem. 284, 4689-4694
11. Sheng, S., Bruns, J. B., and Kleyman, T. R. (2004) J. Biol. Chem. 279, 9743-9749
12. Sheng, S., Maarouf, A. B., Bruns, J. B., Hughey, R. P., and Kleyman, T. R. (2007) J. Biol. Chem. 282, 20180-20190
13. Winarski, K. L., Sheng, N., Chen, J., Kleyman, T. R., and Sheng, S. (2010) J. Biol. Chem. 285, 26088-26096
14. Althaus, M., Bogdan, R., Clauss, W. G., and Fronius, M. (2007) FASEB J. 21, 2389-2399
15. Satlin, L. M., Sheng, S., Woda, C. B., and Kleyman, T. R. (2001) Am. J. Physiol. Renal Physiol 280, F1010-F1018
16. Satlin, L. M., Carattino, M. D., Liu, W., and Kleyman, T. R. (2006) Am. J. Physiol. Renal Physiol 291, F923-F931
17. Sheng, S., Li, J., McNulty, K. A., Avery, D., and Kleyman, T. R. (2000) J. Biol. Chem. 275, 8572-8581
18. Sheng, S., Carattino, M. D., Bruns, J. B., Hughey, R. P., and Kleyman, T. R. (2006) Am. J. Physiol. Renal Physiol 290, F1488-F1496
19. Maarouf, A. B., Sheng, N., Chen, J., Winarski, K. L., Okumura, S., Carattino, M. D., Boyd, C. R., Kleyman, T. R., and Sheng, S. (2009) J. Biol. Chem. 284, 7756-7765
20. Carattino, M. D., Liu, W., Hill, W. G., Satlin, L. M., and Kleyman, T. R. (2007) Am. J. Physiol. Renal Physiol 293, F316-F324
21. Kashlan, O. B., Boyd, C. R., Argyropoulos, C., Okumura, S., Hughey, R. P., Grabe, M., and Kleyman, T. R. (2010) J. Biol. Chem. 285, 35216-35223
22. Hughey, R. P., Bruns, J. B., Kinlough, C. L., Harkleroad, K. L., Tong, Q., Carattino, M. D., Johnson, J. P., Stockand, J. D., and Kleyman, T. R. (2004) J. Biol. Chem. 279, 18111-18114
23. Bruns, J. B., Carattino, M. D., Sheng, S., Maarouf, A. B., Weisz, O. A., Pilewski, J. M., Hughey, R. P., and Kleyman, T. R. (2007) J. Biol. Chem. 282, 6153-6160
24. Carattino, M. D., Hughey, R. P., and Kleyman, T. R. (2008) J. Biol. Chem. 283, 25290-25295
25. Eswar, N., Webb, B., Marti-Renom, M. A., Madhusudhan, M. S., Eramian, D., Shen, M. Y., Pieper, U., and Sali, A. (2006) Current Protocols Bioinformatics, Chapter 6, Unit 5-6