Anti-hyperlipidemic and antioxidant potential of different fractions of Terminalia arjuna Roxb. bark against PX-407 induced hyperlipidemia

Indian Journal of Experimental Biology

Volumn 49, Issue 4, 2011, Pages 282-288

  Subramaniam, Saravanan ^a   Ramachandran, Subramaniam ^b   Uthrapathi, Subasini ^c   Gnamanickam, Victor Rajamanickam ^c   Dubey, Govinda Prasad ^c  

^a PSG COLLEGE OF PHARMACY   (India)

^b KMCH COLLEGE OF PHARMACY   (India)

^c SASTRA UNIVERSITY   (India)

Author keywords

Antioxidant; Coronary heart disease; Hyperlipidemia; Poloxamer 407; Terminalia arjuna

Indexed keywords

ANTILIPEMIC AGENT; ANTIOXIDANT; LIPID; PLANT EXTRACT; POLOXAMER;

ANIMAL; ARTICLE; BARK; BLOOD; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DISEASE MODEL; FEMALE; HYPERLIPIDEMIA; INDIA; ISOLATION AND PURIFICATION; MALE; MEDICINAL PLANT; MOUSE; PHYTOTHERAPY; RAT; TERMINALIA; TRADITIONAL MEDICINE; WISTAR RAT;

ANIMALS; ANTIOXIDANTS; DISEASE MODELS, ANIMAL; FEMALE; HYPERLIPIDEMIAS; HYPOLIPIDEMIC AGENTS; INDIA; LIPIDS; MALE; MEDICINE, TRADITIONAL; MICE; PHYTOTHERAPY; PLANT BARK; PLANT EXTRACTS; PLANTS, MEDICINAL; POLOXAMER; RATS; RATS, WISTAR; TERMINALIA;

RATTUS NORVEGICUS; TERMINALIA; TERMINALIA ARJUNA;

EID: 79955406338     PISSN: 00195189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Davey Smith G, Cholesterol lowering and mortality: The importance of considering initial level of risk, Int Med J, 306 (1993)1367.
2. Grundy S M, Cholesterol and coronary heart disease: A new era, J Am Med Assoc, 256 (1986) 2849.
3. Saravanan R, Rajendra Prasad N & Pugalandi KV, Effect of Piper beetle leaf extract on alcoholic toxicity in the rat brain, J Med Food, 6 (2003) 261.
4. Davey Smith G & Pekkanen J, Should there be a moratorium on the use of cholesterol lowering drugs?, Br Med J, 304 (1992) 431.
5. Brown S L, Lowered serum cholesterol and low mood, Br Med J, 313 (1996) 637.
6. Speight T M & Avery's, Drug treatment principles and practice of clinical pharmacology and therapeutics, (ADIS Press Ltd, Hong Kong) 1987, 599.
7. Berliner J A & Heinecke J W, The role of oxidized lipoproteins in atherogenesis, Free Radic Biol Med, 20 (1996) 707.
8. Johnston T P & Palmer W K, Mechanism of Poloxamer 407-induced hypertriglyceridemia in the rat, Biochem Pharmacol, 46 (1993)1037.
9. Palmer W K, Emeson E E & Johnston T P, The poloxamer 407-induced hyperlipidemic atherogenic animal model, Med Sci Sports Exercise, 29 (1997) 1416.
10. Wasan K M, Subramanian R, Kwong M, Goldberg I J, Wright T & Johnston T P, Poloxamer-407 mediated alterations in the activities of enzymes regulating lipid metabolism in rats, J Pharm Pharmaceut Sci, 6 (2003) 189.
11. Johnston T P, The P-407-induced murine model of dosecontrolled hyperlipidemia and atherosclerosis: A review of findings to date, J Cardiovas Pharmacol, 43 (2004) 595.
12. Dwivedi S & Jauhari R, Beneficial effects of Terminalia arjuna in coronary artery disease, Indian Heart J, 49 (1997) 507.
13. Rane M M & Mengi S A, Comparative effect of oral administration and topical application of alcoholic extract of Terminalia arjuna bark on incision and excision wounds in rats, Fitoterapia, 74 (2003) 553.
14. Perumal Samy R, Ignacimuthu S & Sen A, Screening of 34 Indian medicinal plants for antibacterial properties, J Ethnopharmacol, 62 (1998) 173.
15. Kaur S, Grover I S & Kumar S, Antimutagenic potential of extracts isolated from Terminalia arjuna, J Environ Pathol Toxicol Oncol, 20 (2001) 9.
16. Gupta R, Singhal S, Goyle A & Sharma VN, Antioxidant and hypocholesterolemic effects of Terminalia arjuna tree-bark powder: A randomized placebo-controlled trial, J Assoc Physicians India 49 (2001) 231.
17. Miller A L, Botanical influences on cardiovascular disease, Altern Med Rev, 3 (1998) 422.
18. Chander R, Singh K, Khanna AK, Kaul S M, Puri A, Saxena R, Bhatia G, Rizvi F & Rastogi A K, Antidyslipidemic and antioxidant activities of different fractions of Terminalia arjuna stem bark, Indian J Clin Biochem, 19 (2004) 141.
19. Row L R, Murti D S, Subba Rao GSR, Sastry C S P & Rao K V F, Chemical examination of Terminalia species: Part IIIIsolation and structure determination of arjunetin from Terminalia arjuna species, Indian J Chem, 8 (1970) 772.
20. Kokate C K, Practical pharmacognosy, (Vallabh Prakashan, New Delhi, India) 1994, 107.
21. Cremer D R, Rabeler R, Roberts A & Lynch B, Safety evaluation of Alpha-lipoic acid (ALA), Regul Toxicol Pharmacol, 46 (2006) 29.
22. Allain C C, Poon L S, Chan C S G, Richmond W & Fu P C, Enzymatic determination of total serum cholesterol, Clinical Chem, 20 (1974), 470.
23. Foster L B & Dunn R T, Stable reagents for the determination of serum triglycerides by a colorimetric Hantzch condensation method, J Clin Chem, 19 (1973) 338.
24. Friedwald R I, Levy & Friedrickson D S, Estimation of concentration of LDL cholesterol in plasma without preparation or ultracentrifugation, Clin Chem, 18 (1972) 449.
25. Ohara Y, Peterson T E & Harrison D G, Hypercholesterolemia increases endothelialm superoxide anion production, J Clin Invest, 9 (1993) 2546.
26. Rotruck Pope J T A L, Ganther H E, Swanson A B, Hafeman D G & Hoekstra W G, Selenium: Biochemical role as a component of glutathione peroxidase, Science, 179 (1973) 588.
27. Wout Z G M, Pec E A, Maggiore J A, Williams R H, Palicharla P & Johnston TP, Poloxamer-407 mediated changes in plasma cholesterol and triglyceride following intraperitoneal injection to rats, J Par Sci Tech, 46 (1992) 192.
28. Johnston T P, Coker J W, Paigen B J & Tawfik O, Sex does not seem to influence the formation of aortic lesions in the P-407-induced mouse model of hyperlipidemia and atherosclerosis, J Cardiovas Pharmacol, 39 (2002) 404.
29. Johnston T P, Baker J C, Jamal A S, Hall D, Emeson E E & Palmer W K, Potential downregulation of HMG-CoA reductase after prolonged administration of P-407 in C57BL/6 mice, J Cardiovas Pharmacol, 34 (1999) 831.
30. Srinivasan M N & Srinivasan K, Hypocholesteolemic efficacy of garlic smelling flower Adenocalymma alliaceum in experimental rats, Indian J Exp Biol, 33 (1995) 64.
31. Subba Rao D, Chandrasekhara N, Satyanarayanan M N & Srinivasan M, Effect of curcumin on serum and liver cholesterol levels in the rat, J Nutr, 100 (1970) 1307.
32. Godkar P B, Narayanan P & Bhide S V, Hypocholesterolemic effect of Turmeric extract on Swiss mice, Indian J Pharmacol, 28 (1996) 171.
33. Chatterjee S, Rao A T, Das S N & Agarwal S K, Antiatherogenic action of "Cardipro"-a herbal proprietary formulation, Anci Sci life, 20 (2001) 81.
34. Brown M S & Geldstein J L, Lipoprotein receptors in the liver control signals for plasma cholesterol traffic, J Clin Invest, 72 (1983) 743.
35. Cara L, Armand M, Bore P, Senft M, Portugal H, Pauli A, Lafont H & Lairon D, Long-term wheat germ intake beneficially affects plasma lipids and lipoproteins in hypercholesterolemic human subjects, J Nutr, 122 (1992) 317.
36. Brensike J F, Levy R I, Kelsey S F, Passamani E R, Richardson J M, Loh I K, Stone N J, Aldrich R F, Battaglini J W & Moriarty, Effects of therapy with cholestyramine on progression of coronary arteriosclerosis: Results of the NHLBI type II coronary intervention study, Circulation, 69 (1984) 313.
37. Levy R I M, Brenskie J F, Epstein S E, Kelsey S E, Passama E R, Richardson J M Loh I K, Stone N J, Aldrich R F & Battaglini J W, The influence of changes in lipid values induced by cholestyramine and diet on progression of coronary artery disease: Results of NHLBI Type II Coronary Intervention Study, Circulation, 69 (1984) 325.
38. Andersen P, Hypercoagulability and reduced fibrinolysis in hyperlipidemia: Relationship to the metabolic cardiovascular syndrome, J Cardiovas Pharmacol, 20 (1992) S2.
39. Ghatak A & Asthana OP, Recent trends in hyperlipoproteinaemias and its pharmacotherapy, Indian J Pharmacol, 27 (1995)14.
40. Shaila H P & Udupa A L, Hypolipidemic effect of Terminalia arjuna in cholesterol fed rabbits, Fitoterapia, 68 (1997) 405.
41. Gaur S P S, Ghatak A, Srivastavo J S, Asthan O P, Srimal R C & Dhawan B N. Comparative study of hypolipidaemic effects of guargum and gugulipid, J Assoc Physicians, 39 (1991) 137.
42. Ginsberg H N, Barr S L, Gilbert A, Karmally W, Deckelbaum R, Kaplan K, et al, Reduction of plasma cholesterol levels in normal men on an American heart association Step 1 diet or a Step 1 diet with added monounsaturated fat. N Engl J Med, 322 (1990) 574.
43. Dreon D M, Vranizan K M, Krauss R M, Austin M A & Wood PD, The effects of polyunsaturated fat versus monounsaturated fat on plasma lipoproteins, JAMA, 263 (1990) 2462.
44. Sharma R D, Raghuram T C & Rao V D, Hypolipidaemic effect of fenugreek seeds: A clinical study, Phytother Res, 5 (1991) 145.
45. Phillipson B E, Rothrocj D W, Conner W E, Harris W S & Illingworth D R, Reduction of plasma lipids, lipoproteins, and apoproteins by dietary fish oils in patients with hypertriglyceridemia, N Engl J Med, 312 (1985) 1210.
46. Mata R, Camacho M, Mendoza S & Cruz M C, Phenylstyrene from Hintonia latiflora, Phytochemistry, 31 (1992) 3199.