Association of schizophrenia in 22q11.2 deletion syndrome and gray matter volumetric deficits in the superior temporal gyrus

American Journal of Psychiatry

Volumn 168, Issue 5, 2011, Pages 522-529

  Chow, Eva W C ^a,b,c,d   Ho, Andrew ^a,b,c,d   Wei, Corie ^a,b,c,d   Voormolen, Eduard H J ^a,b,c,d   Crawley, Adrian P ^a,b,c,d   Bassett, Anne S ^a,b,c,d  

^a CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ATYPICAL ANTIPSYCHOTIC AGENT; CHLORPROMAZINE; CLOZAPINE; FLUPHENAZINE; HALOPERIDOL; NEUROLEPTIC AGENT; OLANZAPINE; PERPHENAZINE; QUETIAPINE; RISPERIDONE; ZUCLOPENTHIXOL;

ADULT; AGE DISTRIBUTION; ARTICLE; BRAIN DISEASE; BRAIN SIZE; CEREBROSPINAL FLUID; CHROMOSOME DELETION 22Q11; CLINICAL ARTICLE; CONGENITAL HEART DISEASE; CONTROLLED STUDY; DISEASE DURATION; DISEASE SEVERITY; FALLOT TETRALOGY; FEMALE; GENETIC ASSOCIATION; GRAY MATTER; GRAY MATTER VOLUMETRIC DEFICIT; HUMAN; IMAGE ANALYSIS; INTELLIGENCE QUOTIENT; MALE; MEDICAL HISTORY; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; POSITIVE AND NEGATIVE SYNDROME SCALE; POSITIVE SYNDROME; PREDICTION; PRIORITY JOURNAL; PULMONARY VALVE ATRESIA; RISK FACTOR; SCHIZOPHRENIA; SCORING SYSTEM; SEX DIFFERENCE; STRUCTURE ANALYSIS; SUPERIOR TEMPORAL GYRUS; TEMPORAL LOBE; VOXEL BASED MORPHOMETRY; WHITE MATTER;

ADULT; ANALYSIS OF VARIANCE; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 22; DIGEORGE SYNDROME; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; ORGAN SIZE; SCHIZOPHRENIA; TEMPORAL LOBE;

EID: 79955391338     PISSN: 0002953X     EISSN: 15357228     Source Type: Journal    
DOI: 10.1176/appi.ajp.2010.10081230     Document Type: Article

References (51)

1. Bassett AS, Costain G, Fung WLA, Russell KJ, Pierce L, Kapadia R, Carter RF, Chow EW, Forsythe PJ: Clinically detectable copy number variations in a Canadian catchment population of schizophrenia. J Psychiatr Res 2010; 44:1005-1009
2. Fung WLA, McEvilly R, Fong J, Silversides C , Chow E, Bassett A: Elevated prevalence of generalized anxiety disorder in adults with 22q11.2 deletion syndrome (letter). Am J Psychiatry 2010; 167:998
3. Bassett AS, Scherer SW, Brzustowicz LM: Copy number variations in schizophrenia: critical review and new perspectives on concepts of genetics and disease. Am J Psychiatry 2010; 167:899-914
4. Horowitz A, Shifman S, Rivlin N, Pisante A, Darvasi A: A survey of the 22q11 microdeletion in a large cohort of schizophrenia patients. Schizophr Res 2005; 73:263-267 (Pubitemid 40093888)
5. Bassett AS, Chow EW, Husted J, Weksberg R, Caluseriu O, Webb GD, Gatzoulis MA: Clinical features of 78 adults with 22q11 deletion syndrome. Am J Med Genet A 2005; 138:307-313 (Pubitemid 41532946)
6. McDonald-McGinn DM, Kirschner R, Goldmuntz E, Sullivan K, Eicher P, Gerdes M, Moss E, Solot C , Wang P, Jacobs I, Handler S, Knightly C , Heher K, Wilson M, Ming JE, Grace K, Driscoll D, Pasquariello P, Randall P, Larossa D, Emanuel BS, Zackai EH: The Philadelphia story: the 22q11.2 deletion: report on 250 patients. Genet Couns 1999; 10:11-24 (Pubitemid 29121796)
7. Chow EW, Watson M, Young DA, Bassett AS: Neurocognitive profile in 22q11 deletion syndrome and schizophrenia. Schizophr Res 2006; 87:270-278 (Pubitemid 44428110)
8. De Smedt B, Swillen A, Devriendt K, Fryns JP, Verschaffel L, Ghesquiere P: Mathematical disabilities in children with velocardio- facial syndrome. Neuropsychologia 2007; 45:885-895 (Pubitemid 44958767)
9. Bassett AS, Chow EW: Schizophrenia and 22q11.2 deletion syndrome. Curr Psychiatry Rep 2008; 10:148-157
10. Chow EW, Zipursky RB, Mikulis DJ, Bassett AS: Structural brain abnormalities in patients with schizophrenia and 22q11 deletion syndrome. Biol Psychiatry 2002; 51:208-215 (Pubitemid 34142632)
11. Murphy KC , Jones LA, Owen MJ: High rates of schizophrenia in adults with velo-cardio-facial syndrome. Arch Gen Psychiatry 1999; 56:940-945 (Pubitemid 29480131)
12. Eisenberg DP, Jabbi M, Berman KF: Bridging the gene-behavior divide through neuroimaging deletion syndromes: velocardiofacial (22q11.2 deletion) and Williams (7q11.23 deletion) syndromes. Neuroimage 2010; 53:857-869
13. van Amelsvoort T, Daly E, Henry J, Robertson D, Ng V, Owen M, Murphy KC , Murphy DG: Brain anatomy in adults with velocardiofacial syndrome with and without schizophrenia: preliminary results of a structural magnetic resonance imaging study. Arch Gen Psychiatry 2004; 61:1085-1096 (Pubitemid 39463409)
14. Schaer M, Debbane M, Bach Cuadra M, Ottet MC, Glaser B, Thiran JP, Eliez S: Deviant trajectories of cortical maturation in 22q11.2 deletion syndrome (22q11DS): a cross-sectional and longitudinal study. Schizophr Res 2009; 115:182-190
15. Honea R, Crow TJ, Passingham D, Mackay CE: Regional deficits in brain volume in schizophrenia: a meta-analysis of voxel-based morphometry studies. Am J Psychiatry 2005; 162:2233-2245 (Pubitemid 41740200)
16. Takahashi T, Wood SJ, Soulsby B, Kawasaki Y, McGorry PD, Suzuki M, Velakoulis D, Pantelis C: An MRI study of the superior temporal subregions in first-episode patients with various psychotic disorders. Schizophr Res 2009; 113:158-166
17. Job DE, Whalley HC, Johnstone EC, Lawrie SM: Grey matter changes over time in high risk subjects developing schizophrenia. Neuroimage 2005; 25:1023-1030 (Pubitemid 40591646)
18. Bassett AS, Marshall CR, Lionel AC, Chow EW, Scherer SW: Copy number variations and risk for schizophrenia in 22q11.2 deletion syndrome. Hum Mol Genet 2008; 17:4045-4053 (Pubitemid 352762863)
19. Bassett AS, Chow EWC, AbdelMalik P, Gheorghiu M, Husted J, Weksberg R: The schizophrenia phenotype in 22q11 deletion syndrome. Am J Psychiatry 2003; 160 :1580-1586 (Pubitemid 41079542)
20. Bassett AS, Chow EW, Husted J, Hodgkinson K A, Oechslin E, Harris L, Silversides C: Premature death in adults with 22q11.2 deletion syndrome. J Med Genet 2009; 46:324-330
21. Bassett AS, Caluseriu O, Weksberg R, Young DA, Chow EW: Catechol-O-methyl transferase and expression of schizophrenia in 73 adults with 22q11 deletion syndrome. Biol Psychiatry 2007; 61:1135-1140 (Pubitemid 46669459)
22. Kay SR, Fiszbein A, Opler LA: The Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Schizophr Bull 1987; 13:261-276 (Pubitemid 18039085)
23. Kroken R A, Johnsen E, Ruud T, Wentzel-Larsen T, Jorgensen HA: Treatment of schizophrenia with antipsychotics in Norwegian emergency wards: a cross-sectional national study. BMC Psychiatry 2009; 16:9-24
24. Voormolen EH, Wei C, Chow EW, Bassett AS, Mikulis DJ, Crawley AP: Voxel-based morphometry and automated lobar volumetry: the trade-off between spatial scale and statistical correction. Neuroimage 2010 ; 49:587-596
25. A shburner J, Friston KJ: Unified segmentation. Neuroimage 2005; 26:839-851
26. Walter B, Blecker C, Kirsch P, Sammer G, Schienle A, Stark R, Vaitl D: MARINA: an easy to use tool for the creation of MA sks for Region of INterest Analyses, in Proceedings of the Ninth International Conference on Functional Mapping of the Human Brain. New York, Neuroimage, 2003
27. Tzourio-Mazoyer N, Landeau B, Papathanassiou D, Crivello F, Etard O, Delcroix N, Mazoyer B, Joliot M: Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage 2002; 15:273-289 (Pubitemid 34852226)
28. Gartus A, Foki T, Geissler A, Beisteiner R: Improvement of clinical language localization with an overt semantic and syntactic language functional MR imaging paradigm. AJNR Am J Neuroradiol 2009; 30 :1977-1985
29. Bergouignan L, Chupin M, C zechowska Y, Kinkingnehun S, Lemogne C, Le Bastard G, Lepage M, Garnero L, Colliot O, Fossati P: Can voxel based morphometry, manual segmentation, and automated segmentation equally detect hippocampal volume differences in acute depression? Neuroimage 2009; 45:29-37
30. Brunner R, Henze R, Parzer P, Kramer J, Feigl N, Lutz K, Essig M, Resch F, Stieltjes B: Reduced prefrontal and orbitofrontal gray matter in female adolescents with borderline personality disorder: is it disorder specific? Neuroimage 2010 ; 49:114-120
31. Keshavan MS, Haas GL, Kahn CE, Aguilar E, Dick EL, Schooler NR, Sweeney JA, Pettegrew JW: Superior temporal gyrus and the course of early schizophrenia: progressive, static, or reversible? J Psychiatr Res 1998; 32:161-167 (Pubitemid 28408280)
32. Shenton ME, Dickey CC, Frumin M, McCarley RW: A review of MRI findings in schizophrenia. Schizophr Res 2001; 49:1-52 (Pubitemid 32451739)
33. Pearlson GD: Superior temporal gyrus and planum temporale in schizophrenia: a selective review. Prog Neuropsychopharmacol B iol Psychiatry 1997; 21:1203-1229
34. Takahashi T, Wood SJ, Yung AR, Walterfang M, Phillips LJ, Soulsby B, Kawasaki Y, McGorry PD, Suzuki M, Velakoulis D, Pantelis C: Superior temporal gyrus volume in antipsychotic-naive people at risk of psychosis. Br J Psychiatry 2010 ; 196:206-211
35. Bearden CE, van Erp TG, Dutton R A, Lee AD, Simon TJ, Cannon TD, Emanuel BS, McDonald-McGinn D, Zackai EH, Thompson PM: Alterations in midline cortical thickness and gyrification patterns mapped in children with 22q11.2 deletions. Cereb Cortex 2009; 19:115-126
36. Costain G, Ho A, Crawley AP, Mikulis DJ, Brzustowicz LM, Chow EW, Bassett AS: Reduced gray matter in the anterior cingulate gyrus in familial schizophrenia: a preliminary report. Schizophr Res 2010; 122:81-84
37. Kasai K, Shenton ME, Salisbury DF, Hirayasu Y, Onitsuka T, Spencer MH, Yurgelun-Todd DA, Kikinis R, Jolesz FA, McCarley RW: Progressive decrease of left Heschl gyrus and planum temporale gray matter volume in first-episode schizophrenia: a longitudinal magnetic resonance imaging study. Arch Gen Psychiatry 2003; 60:766-775 (Pubitemid 36960908)
38. Kim JJ, Crespo-Facorro B, Andreasen NC, O'Leary DS, Magnotta V, Nopoulos P: Morphology of the lateral superior temporal gyrus in neuroleptic naive patients with schizophrenia: relationship to symptoms. Schizophr Res 2003; 60:173-181 (Pubitemid 36187457)
39. Gothelf D, Penniman L, Gu E, Eliez S, Reiss AL: Developmental trajectories of brain structure in adolescents with 22q11.2 deletion syndrome: a longitudinal study. Schizophr Res 2007; 96:72-81 (Pubitemid 47494637)
40. Kwon JS, McCarley RW, Hirayasu Y, Anderson JE, Fischer IA, Kikinis R, Jolesz FA, Shenton ME: Left planum temporale volume reduction in schizophrenia. Arch Gen Psychiatry 1999; 56:142-148 (Pubitemid 29081388)
41. Sumich A, Chitnis X A, Fannon DG, O'Ceallaigh S, Doku VC, Falrowicz A, Marshall N, Matthew VM, Potter M, Sharma T: Temporal lobe abnormalities in first-episode psychosis. Am J Psychiatry 2002; 159:1232-1235
42. Marsh L, Suddath RL, Higgins N, Weinberger DR: Medial temporal lobe structures in schizophrenia: relationship of size to duration of illness. Schizophr Res 1994; 11:225-238 (Pubitemid 24063742)
43. Crespo-Facorro B, Nopoulos PC, Chemerinski E, Kim JJ, Andreasen NC, Magnotta V: Temporal pole morphology and psychopathology in males with schizophrenia. Psychiatry Res 2004; 132:107-115 (Pubitemid 39643008)
44. Lieberman JA, Tollefson GD, Charles C, Zipursky R, Sharma T, Kahn RS, Keefe RS, Green AI, Gur RE, McEvoy J, Perkins D, Hamer RM, Gu H, Tohen M: Antipsychotic drug effects on brain morphology in first-episode psychosis. Arch Gen Psychiatry 2005; 62:361-370 (Pubitemid 40471685)
45. Chow EW, Mikulis DJ, Zipursky RB, Scutt LE, Weksberg R, Bassett AS: Qualitative MRI findings in adults with 22q11 deletion syndrome and schizophrenia. Biol Psychiatry 1999; 46:1436-1442
46. Kiehl TR, Chow EWC, Mikulis DJ, George SR, Bassett AS: Neuropathologic features in adults with 22q11.2 deletion syndrome. Cereb Cortex 2009; 19:153-164
47. Meechan DW, Maynard TM, Gopalakrishna D, Wu Y, LaMantia AS: When half is not enough: gene expression and dosage in the 22q11 deletion syndrome. Gene Expr 2007; 13:299-310 (Pubitemid 47289403)
48. Sivagnanasundaram S, Fletcher D, Hubank M, Illingworth E, Skuse D, Scambler P: Differential gene expression in the hippocampus of the Df1/+ mice: a model for 22q11.2 deletion syndrome and schizophrenia. Brain Res 2007; 1139:48-59
49. Chow EW, Husted J, Weksberg R, Bassett AS: Postmaturity in a genetic subtype of schizophrenia. Acta Psychiatr Scand 2003; 108:260-268 (Pubitemid 37175900)
50. Bearden CE, van Erp TG, Monterosso JR, Simon TJ, Glahn DC, Saleh PA, Hill NM, McDonald-McGinn DM, Zackai E, Emanuel BS, Cannon TD: Regional brain abnormalities in 22q11.2 dele tion syndrome: association with cognitive abilities and behavioral symptoms. Neurocase 2004; 10:198-206 (Pubitemid 39430018)
51. Bowden NA, Scott RJ, Tooney PA: Altered gene expression in the superior temporal gyrus in schizophrenia. BMC Genomics 2008; 9:199