The essential two-component system YhcSR is involved in regulation of the nitrate respiratory pathway of Staphylococcus aureus

Journal of Bacteriology

Volumn 193, Issue 8, 2011, Pages 1799-1805

  Yan, Meiying ^a   Yu, Chuanxin ^a   Yang, Junshu ^a   Ji, Yinduo ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; BACTERIAL PROTEIN; NARG PROTEIN; NITRATE; NITRATE REDUCTASE; NREABC PROTEIN; UNCLASSIFIED DRUG; YHCSR PROTEIN;

ANAEROBIC BACTERIUM; ARTICLE; BACTERIAL GROWTH; CONTROLLED STUDY; DOWN REGULATION; GENETIC TRANSCRIPTION; NITRATE METABOLISM; NITRATE RESPIRATORY PATHWAY; NONHUMAN; OPERON; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY CHAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STAPHYLOCOCCUS AUREUS;

ANAEROBIOSIS; ARTIFICIAL GENE FUSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; GENES, REPORTER; LUCIFERASES; MEMBRANE PROTEINS; METABOLIC NETWORKS AND PATHWAYS; NITRATES; OXIDATION-REDUCTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STAPHYLOCOCCUS AUREUS; TRANSCRIPTION FACTORS;

BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS AUREUS;

EID: 79955375769     PISSN: 00219193     EISSN: 10985530     Source Type: Journal    
DOI: 10.1128/JB.01511-10     Document Type: Article

References (34)

1. Birkey, S. M., W. Liu, X. Zhang, M. F. Duggan, and F. M. Hulett. 1998. Pho signal transduction network reveals direct transcriptional regulation of one two-component system by another two-component regulator: Bacillus subtilis PhoP directly regulates production of the ResD. Mol. Microbiol. 30:943-953.
2. Burke, K. A., and J. Lascelles. 1975. Nitrate reductase system in Staphylococcus aureus wild type and mutants. J. Bacteriol. 123:308-316.
3. Cramton, S., M. Ulrich, F. Gotz, and G. Doring. 2001. Anaerobic conditions induce expression of polysaccharide intercellular adhesin in Staphylococcus aureus and Staphylococcus epidermidis. Infect. Immun. 69:5427-5433.
4. Fedtke, I., A. Kamps, B. Krismer, and F. Gotz. 2002. The nitrate reductase and nitrite reductase operons and the narT gene of Staphylococcus carnosus are positively controlled by the novel two-component system NreBC. J. Bacteriol. 184:6624-6634.
5. Forsyth, R. A., et al. 2002. A genome-wide strategy for the identification of essential genes in Staphylococcus aureus. Mol. Microbiol. 43:1387-1400.
6. Fuchs, S., J. Pane-Farre, C. Kohler, M. Hecker, and S. Engelmann. 2007. Anaerobic gene expression in Staphylococcus aureus. J. Bacteriol. 189:4275-4289.
7. Gross, R. 1993. Signal transduction and virulence regulation in human and animal pathogens. FEMS Microbiol. 10:301-326.
8. Grundmann, H., M. Aires-de-Sousa, J. Boyce, and E. Tiemersma. 2006. Emergence and resurgence of methicillin-resistant Staphylococcus aureus as a public-health threat. Lancet 368:874-885.
9. Huang, K. J., C. Y. Lan, and M. M. Igo. 1997. Phosphorylation stimulates the cooperative DNA-binding properties of the transcription factor OmpR. Proc. Natl. Acad. Sci. U. S. A. 94:2828-2832.
10. Ji, Y., G. Woodnutt, M. Rosenberg, and M. K. R. Burnham. 2002. Identification of essential genes in Staphylococcus aureus using inducible antisense RNA. Methods Enzymol. 358:123-128.
11. Ji, Y., C. Yu, and X. Liang. 2007. Transcriptomic analysis of ArlSR twocomponent signaling operon in Staphylococcus aureus. Methods Enzymol. 423:502-513.
12. Kamps, A., S. Achebach, I. Fedtke, G. Unden, and F. Götz. 2004. Staphylococcal NreB: an O(2)-sensing histidine protein kinase with an O(2)-labile iron-sulphur cluster of the FNR type. Mol. Microbiol. 52:713-723.
13. Kazakova, S. V., et al. 2005. A clone of methicillin-resistant Staphylococcus aureus among professional football players. N. Engl. J. Med. 352:468-475.
14. Kuroda, M., et al. 2003. Two-component system VraSR positively modulates the regulation of cell-wall biosynthesis pathway in Staphylococcus aureus. Mol. Microbiol. 19:807-821.
15. Li, Y. H., et al. 2002. Novel two-component regulatory system involved in biofilm formation and acid resistance in Streptococcus mutans. J. Bacterol. 184:6333-6342.
16. Liang, X., et al. 2005. Global regulation of gene expression by ArlRS, a two-component signal transduction regulatory system of Staphylococcus aureus. J. Bacteriol. 187:5486-5549.
17. Manna, A., S. Ingavale, M. Maloney, W. van Wamel, and A. L. Cheung. 2004. Identification of sarV (SA2062), a new transcriptional regulator, is repressed by SarA and MgrA (SA0641) and involved in the regulation of autolysis in Staphylococcus aureus. J. Bacteriol. 186:5267-5280.
18. Manna, A., and A. L. Cheung. 2006. Transcriptional regulation of the agr locus and the identification of DNA binding residues of the global regulatory protein SarR in Staphylococcus aureus. Mol. Microbiol. 60:1289-1301.
19. Martin, P. K., T. Li, D. Sun, D. P. Biek, and M. B. Schmid. 1999. Role in cell permeability of an essential two-component system in Staphylococcus aureus. J. Bacteriol. 181:3666-3673.
20. Miller, A. A., N. C. Engleberg, and V. J. DiRita. 2001. Repression of virulence genes by phosphorylation-dependent oligomerization of CsrR at target promoters in S. pyogenes. Mol. Microbiol. 40:976-990.
21. Neubauer, H., and F. Gotz. 1996. Physiology and interaction of nitrate and nitrite reduction in Staphylococcus carnosus. J. Bacteriol. 178:2005-2009.
22. Novick, R. 2006. Staphylococcal pathogenesis and pathogenicity factors: genetics and regulation, p. 496-516. In V. Fischetti et al. (ed.), Gram-positive pathogens. ASM Press, Washington, DC.
23. Park, M., R. Myers, and L. Marzella. 1992. Oxygen tensions and infections: modulation of microbial growth, activity of antibacterial agents, and immunologic responses. Clin. Infect. Dis. 14:720-740.
24. Pragman, A., J. Yarwood, T. Tripp, and P. M. Schlievert. 2004. Characterization of virulence factor regulation by SrrAB, a two-component system in Staphylococcus aureus. J. Bacteriol. 186:2430-2438.
25. Rice, L. 2006. Antimicrobial resistance in Gram-positive bacteria. Am. J. Med. 119:S11-S19.
26. Schlag, S., et al. 2008. Characterization of the oxygen-responsive NreABC regulon of Staphylococcus aureus. J. Bacteriol. 190:7847-7858.
27. Stock, A. M., V. L. Robinson, and P. N. Goudreau. 2000. Two-component signal transduction. Annu. Rev. Biochem. 69:183-215.
28. Strasters, K. C., and K. C. Winkler. 1963. Carbohydrate metabolism of Staphylococcus aureus. J. Gen. Microbiol. 33:213-229.
29. Sun, J., L. Zheng, C. Landwehr, J. Yang, and Y. Ji. 2005. Identification of a novel essential two-component signal transduction system, YhcSR, in Staphylococcus aureus. J. Bacteriol. 187:7876-7880.
30. Throup, J. P., et al. 2001. The srhSR gene pair from Staphylococcus aureus: genomic and proteomic approaches to the identification and characterization of gene function. Biochemistry 40:10392-10401.
31. Unden, G., and J. Schirawski. 1997. The oxygen-responsive transcriptional regulator FNR of Escherichia coli: the search for signals and reactions. Mol. Microbiol. 25:205-210.
32. Yan, M., C. Yu, J. Yang, and Y. Ji. 2009. Development of shuttle vectors for evaluation of essential regulator regulated gene expression in Staphylococcus aureus. Plasmid. 61:188-192.
33. Yarwood, J. M., J. McCormick, and P. M. Schlievert. 2001. Identification of a novel two-component regulatory system that acts in global regulation of virulence factors of Staphylococcus aureus. J. Bacteriol. 183:1113-1123.
34. Yarwood, J. M., and P. M. Schlievert. 2000. Oxygen and carbon dioxide regulation of toxic shock syndrome toxin 1 production by Staphylococcus aureus MN8. J. Clin. Microbiol. 38:1797-1803.