Wt1 controls retinoic acid signalling in embryonic epicardium through transcriptional activation of Raldh2s

Development

Volumn 138, Issue 6, 2011, Pages 1093-1097

  Guadix, Juan Antonio ^a   Ruiz Villalba, Adrián ^a   Lettice, Laura ^b   Velecela, Victor ^b   Muñoz Chápuli, Ramón ^a   Hastie, Nicholas D ^b   Pérez Pomares, José María ^a   Martínez Estrada, Ofelia M ^b  

^a UNIVERSITY OF MÁLAGA   (Spain)

^b WESTERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

Epicardium; Mouse embryo; Raldh2; Retinoic acid; Wilms' tumour suppressor gene

Indexed keywords

MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN RALDH2; RETINOIC ACID; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; WT1 PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; DOWN REGULATION; EMBRYO; EMBRYO DEVELOPMENT; EPICARDIUM; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRANSCRIPTION INITIATION;

ALDEHYDE OXIDOREDUCTASES; ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; EMBRYO, MAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKDOWN TECHNIQUES; HEART; MICE; MICE, TRANSGENIC; PERICARDIUM; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION; TRETINOIN; WT1 PROTEINS;

EID: 79955141545     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.044594     Document Type: Article

References (39)

1. Bayha, E., Jørgensen, M. C., Serup, P. and Grapin-Botton, A. (2009). Retinoic acid signalling organizes endodermal organ specification along the entire anteroposterior axis. PLoS One 4, e5845.
2. Chen, J., Kubalak, S. W. and Chien, K. R. (1998). Ventricular muscle-restricted targeting of the RXRalpha gene reveals a non-cell-autonomous requirement in cardiac chamber morphogenesis. Development 125, 1943-1949.
3. Chen, T. H., Chang, T. C., Kang, J. O., Choudhary, B., Makita, T., Tran, C. M., Burch, J. B., Eid, H. and Sucov, H. M. (2002). Epicardial induction of fetal cardiomyocyte proliferation via a retinoic acid-inducible trophic factor. Dev. Biol. 250, 198-207.
4. Dettman, R. W., Denetclaw, W., Jr, Ordahl, C. P. and Bristow, J. (1998). Common epicardial origin of coronary vascular smooth muscle, perivascular fibroblasts, and intermyocardial fibroblasts in the avian heart. Dev. Biol. 193, 169-181.
5. Duester, G. (2008). Retinoic acid synthesis and signalling during early organogenesis. Cell 134, 921-931.
6. Goodyer, P., Dehbi, M., Torban, E., Bruening, W. and Pelletier, J. (1995). Repression of the retinoic acid receptor-alpha gene by the Wilms' tumor suppressor gene product, wt1. Oncogene 10, 1125-1129.
7. Guadix, J. A., Carmona, R., Muñoz-Chápuli, R. and Pérez-Pomares, J. M. (2006). In vivo and in vitro analysis of the vasculogenic potential of avian proepicardial and epicardial cells. Dev. Dyn. 235, 1014-1026.
8. Hochgreb, T., Linhares, V. L., Menezes, D. C., Sampaio, A. C., Yan, C. Y., Cardoso, W. V., Rosenthal, N. and Xavier-Neto, J. (2003). A caudorostral wave of RALDH2 conveys anteroposterior information to the cardiac field. Development 130, 5363-5374.
9. Hosen, N., Shirakata, T., Nishida, S., Yanagihara, M., Tsuboi, A., Kawakami, M., Oji, Y., Oka, Y., Okabe, M., Tan, B. et al. (2007). The Wilms' tumor gene WT1-GFP knock-in mouse reveals the dynamic regulation of WT1 expression in normal and leukemic hematopoiesis. Leukemia 21, 1783-1791.
10. IJpenberg, A., Pérez-Pomares, J. M., Guadix, J. A., Carmona, R., Portillo-Sánchez, V., Macías, D., Hohenstein, P., Miles, C. M., Hastie, N. D. and Muñoz-Chápuli, R. (2007). Wt1 and retinoic acid signalling are essential for stellate cell development and liver morphogenesis. Dev. Biol. 312, 157-170.
11. Jat, P. S., Noble, M. D., Ataliotis, P., Tanaka, Y., Yannoutsos, N., Larsen, L. and Kioussis, D. (1991). Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse. Proc. Natl. Acad. Sci. USA 88, 5096-5100.
12. Kang, J., Gu, Y., Li, P., Johnson, B. L., Sucov, H. M. and Thomas, P. S. (2008). PDGF-A as an epicardial mitogen during heart development. Dev. Dyn. 237, 692-701.
13. Kang, J. O. and Sucov, H. M. (2005). Convergent proliferative response and divergent morphogenic pathways induced by epicardial and endocardial signalling in fetal heart development. Mech. Dev. 122, 57-65.
14. Kastner, P., Grondona, J. M., Mark, M., Gansmuller, A., LeMeur, M., Decimo, D., Vonesch, J. L., Dollé, P. and Chambon, P. (1994). Genetic analysis of RXR alpha developmental function, convergence of RXR and RAR signalling pathways in heart and eye morphogenesis. Cell 78, 987-1003.
15. Kreidberg, J. A., Sariola, H., Loring, J. M., Maeda, M., Pelletier, J., Housman, D. and Jaenisch, R. (1993). WT-1 is required for early kidney development. Cell 74, 679-691.
16. Landerholm, T. E., Dong, X. R., Lu, J., Belaguli, N. S., Schwartz, R. J. and Majesky, M. W. (1999). A role for serum response factor in coronary smooth muscle differentiation from proepicardial cells. Development 126, 2053-2062.
17. Lavine, K. J., Yu, K., White, A. C., Zhang, X., Smith, C., Partanen, J. and Ornitz, D. M. (2005). Endocardial and epicardial derived FGF signals regulate myocardial proliferation and differentiation in vivo. Dev. Cell 8, 85-95.
18. Liebeskind, A., Srinivasan, S., Kaetzel, D. and Bruce, M. (2000). Retinoic acid stimulates immature lung fibroblast growth via a PDGF-mediated autocrine mechanism. Am. J. Physiol. Lung Cell. Mol. Physiol. 279, 81-90.
19. Lu, J., Landerholm, T. E., Wei, J. S., Dong, X.-R., Wu, S.-P., Liu, X., Nagata, K., Inagaki, M. and Majesky, M. W. (2001). Coronary smooth muscle differentiation from proepicardial cells requires RhoA-mediated actin reorganization and p160 Rho-kinase activity. Dev. Biol. 240, 404-418.
20. Martínez-Estrada, O. M., Lettice, L. A., Essafi, A., Guadix, J. A., Slight, J., Velecela, V., Hall, E., Reichmann, J., Devenney, P. S., Hohenstein, P. et al. (2010). Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin. Nat. Genet. 42, 89-93.
21. Mellgren, A. M., Smith, C. L., Olsen, G. S., Eskiocak, B., Zhou, B., Kazi, M. N., Ruiz, F. R., Pu, W. T. and Tallquist, M. D. (2008). Platelet-derived growth factor receptor beta signalling is required for efficient epicardial cell migration and development of two distinct coronary vascular smooth muscle cell populations. Circ. Res. 103, 1393-1401.
22. Merki, E., Zamora, M., Raya, A., Kawakami, Y., Wang, J., Zhang, X., Burch, J., Kubalak, S. W., Kaliman, P., Belmonte, J. C. et al. (2005). Epicardial retinoid X receptor alpha is required for myocardial growth and coronary artery formation. Proc. Natl. Acad. Sci. USA 102, 18455-18460.
23. Mjaatvedt, C. H., Lepera, R. C. and Markwald, R. R. (1987). Myocardial specificity for initiating endothelial-mesenchyma transition by an in vivo adheron-like complex. Dev. Biol. 136, 118-128.
24. Moore, A. W., McInnes, L., Kreidberg, J., Hastie, N. D. and Schedl, A. (1999). YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis. Development 126, 1845-1857.
25. Moss, J. B., Xavier-Neto, J., Shapiro, M. D., Nayeem, S. M., McCaffery, P., Dräger, U. C. and Rosenthal, N. (1998). Dynamic patterns of retinoic acid synthesis and response in the developing mammalian heart. Dev. Biol. 199, 55-71.
26. Niederreither, K., McCaffery, P., Dräger, U. C., Chambon, P. and Dollé, P. (1997). Restricted expression and retinoic acid-induced downregulation of the retinaldehyde dehydrogenase type 2 (RALDH-2) gene during mouse development. Mech. Dev. 62, 67-78.
27. Niederreither, K., Vermot, J., Messaddeq, N., Schuhbaur, B., Chambon, P. and Dollé, P. (2001). Embryonic retinoic acid synthesis is essential for heart morphogenesis in the Mouse. Development 128, 1019-1031.
28. Niederreither, K., Fraulob, V., Garnier, J. M., Chambon, P. and Dollé, P. (2002). Differential expression of retinoic acid-synthesizing (RALDH) enzymes during fetal development and organ differentiation in the mouse. Mech. Dev. 110, 165-171.
29. Norden, J., Grieskamp, T., Lausch, E., van Wijk, B., van den Hoff, M. J., Englert, C., Petry, M., Mommersteeg, M. T., Christoffels, V. M., Niederreither, K. et al. (2010). Wt1 and retinoic acid signalling in the subcoelomic mesenchyme control the development of the pleuropericardial membranes and the sinus horns. Circ. Res. 106, 1212-1220.
30. Pérez-Pomares, J. M., Macías, D., García-Garrido, L. and Muñoz-Chápuli, R. (1998). The origin of the subepicardial mesenchyme in the avian embryo: an immunohistochemical and quail-chick chimaera study. Dev. Biol. 200, 57-68.
31. Pérez-Pomares, J. M., Phelps, A., Sedmerova, M., Carmona, R., González-Iriarte, M., Muñoz-Chápuli, R. and Wessels, A. (2002). Experimental studies on the spatiotemporal expression of Wt1 and RALDH2 in the embryonic avian heart: a model for the regulation of myocardial and valvuloseptal development by epicardially-derived cells (EPDCs). Dev. Biol. 247, 307-326.
32. Sinning, A. (1998). Role of vitamin A in the formation of congenital heart defects. Anat. Rec. 253, 147-153.
33. Sucov, H. M., Dyson, E., Gumeringer, C. L. and Price, R. M. (1994). RXRa mutant mice establish a genetic basis for vitamin A signalling in heart morphogenesis. Genes Dev. 8, 1007-1018.
34. Tomanek, R. J., Zheng, W., Peters, K. G., Lin, P., Holifield, J. S. and Suvarna, P. R. (2001). Multiple growth factors regulate coronary embryonic vasculogenesis. Dev. Dyn. 221, 265-273.
35. Tomanek, R. J., Hansen, H. K. and Christensen, L. P. (2008). Temporally expressed PDGF and FGF-2 regulate embryonic coronary artery formation and growth. Arterioscler. Thromb. Vasc. Biol. 28, 1237-1243.
36. Tsukamoto, T., Matsui, T., Takaishi, T., Ito, M., Fukase, M. and Chihara, K. (1994). Retinoic acid differentially affects platelet-derived growth factor and epidermal growth factor-regulated cell growth of mouse osteoblast-like cells. Cell Growth Differ. 5, 207-212.
37. Wessels, A. and Pérez-Pomares, J. M. (2004). The epicardium and epicardiallyderived cells (EPDCs) as cardiac stem cells. Anat. Rec. 276, 43-57.
38. Xavier-Neto, J., Shapiro, M. D., Houghton, L. and Rosenthal, N. (2000). Sequential programs of retinoic acid synthesis in the myocardial and epicardial layers of the developing avian heart. Dev. Biol. 219, 129-141.
39. Yuan, J. S., Reed, A., Chen, F. and Stewart, C. N., Jr (2006). Statistical analysis of real-time PCR data. BMC Bioinformatics 7, 85.