Sc237 hamster PrPSc and Sc237-derived mouse PrPSc generated by interspecies in vitro amplification exhibit distinct pathological and biochemical properties in tga20 transgenic mice

Microbiology and Immunology

Volumn 55, Issue 5, 2011, Pages 331-340

  Yoshioka, Miyako ^a   Imamura, Morikazu ^a   Okada, Hiroyuki ^a   Shimozaki, Noriko ^a   Murayama, Yuichi ^a   Yokoyama, Takashi ^a   Mohri, Shirou ^a  

^a NATIONAL INSTITUTE OF ANIMAL HEALTH   (Japan)

Author keywords

Prion; Protein misfolding cyclic amplification; Species barrier; Strain diversity

Indexed keywords

PRION PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; BRAIN HOMOGENATE; BRAIN LEVEL; CONTROLLED STUDY; HAMSTER; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; INFECTION SENSITIVITY; MOUSE; NONHUMAN; PROTEIN DEFECT; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN LOCALIZATION; SCRAPIE; SCRAPIE AGENT; TRANSGENIC MOUSE; VIRUS STRAIN; VIRUS TRANSMISSION; VIRUS VIRULENCE; ANIMAL; BRAIN; CHEMISTRY; DISEASE TRANSMISSION; GENETICS; METABOLISM; PATHOGENICITY; PATHOLOGY; PRION; PRION DISEASE; SPECIES DIFFERENCE;

CRICETINAE; MUS; MUS MUSCULUS; SCRAPIE PRION;

ANIMALS; BRAIN; CRICETINAE; MICE; MICE, TRANSGENIC; PRION DISEASES; PRIONS; PROTEIN FOLDING; PRPSC PROTEINS; SCRAPIE; SPECIES SPECIFICITY;

EID: 79955135484     PISSN: 03855600     EISSN: 13480421     Source Type: Journal    
DOI: 10.1111/j.1348-0421.2011.00328.x     Document Type: Article

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