Does the donor mannose-binding lectin genotype really predict the risk of bacterial infections after liver transplantation?

Hepatology

Volumn 53, Issue 5, 2011, Pages 1786-1787

  Curvelo, Lilian A ^a   de Mare Bredemeijer, Emmeloes ^a   de Canck, Ilse ^c   van Thielen, Martine ^c   Kazemier, Geert ^b   Metselaar, Herold ^a   Kwekkeboom, Jaap ^a  

^a Departments of Gastroenterology and Hepatology   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c Innogenetics NV   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

FICOLIN 2; LECTIN; MANNAN BINDING LECTIN ASSOCIATED SERINE PROTEASE 2; MANNOSE BINDING LECTIN 2; UNCLASSIFIED DRUG;

ABDOMINAL INFECTION; BACTEREMIA; BACTERIAL INFECTION; BLOOD LEVEL; CLINICAL ASSESSMENT; COMPLEMENT LECTIN PATHWAY; DONOR; GENOTYPE; GRAFT RECIPIENT; HUMAN; INFECTION RISK; LETTER; LIVER TRANSPLANTATION; PNEUMONIA; POSTOPERATIVE INFECTION; PREDICTIVE VALUE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK ASSESSMENT; SEPTIC SHOCK; SINGLE NUCLEOTIDE POLYMORPHISM;

BACTERIAL INFECTIONS; COMPLEMENT PATHWAY, MANNOSE-BINDING LECTIN; GENOTYPE; HUMANS; LIVER TRANSPLANTATION; MANNOSE-BINDING LECTIN; POSTOPERATIVE COMPLICATIONS; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; RISK FACTORS; TISSUE DONORS;

EID: 79955110349     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.24114     Document Type: Letter

References (5)

1. de Rooij BJ, van Hoek B, ten Hove WR, Roos A, Bouwman LH, Schaapherder AF, et al. Lectin complement pathway gene profile of donor and recipient determine the risk of bacterial infections after orthotopic liver transplantation. HEPATOLOGY 2011; 52: 1100-1110.
2. Razonable RR. Innate immune genetic profile to predict infection risk and outcome after liver transplant. HEPATOLOGY 2011; 52: 814-817.
3. Bouwman LH, Roos A, Terpstra OT, de Knijff P, van Hoek B, Verspaget HW, et al. Mannose binding lectin gene polymorphisms confer a major risk for severe infections after liver transplantation. Gastroenterology 2005; 129: 408-414.
4. Worthley DL, Johnson DF, Eisen DP, Dean MM, Heatley SL, Tung JP, et al. Donor mannose-binding lectin deficiency increases the likelihood of clinically significant infection after liver transplantation. Clin Infect Dis 2009; 48: 410-417.
5. Cervera C, Balderramo D, Suarez B, Prieto J, Fuster F, Linares L, et al. Donor mannose-binding lectin gene polymorphisms influence the outcome of liver transplantation. Liver Transpl 2009; 15: 1217-1224.