High hepatitis B virus DNA level in serum before liver transplantation increases the risk of hepatocellular carcinoma recurrence

Digestion

Volumn 84, Issue 2, 2011, Pages 134-141

  Li, Min Ru ^a   Chen, Gui Hua ^a   Cai, Chang Jie ^a   Wang, Guo Ying ^a   Zhao, Hui ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Hepatitis B virus; Hepatocellular carcinoma; Liver transplantation

Indexed keywords

CYCLOSPORIN; METHYLPREDNISOLONE; STEROID; TACROLIMUS; VIRUS DNA;

ADOLESCENT; ADULT; AGED; ARTICLE; BILE DUCT CARCINOMA; CANCER RECURRENCE; CANCER RISK; CHILD; CONTROLLED STUDY; FEMALE; GRAFT REJECTION; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LIVER CELL CARCINOMA; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; ORTHOTOPIC TRANSPLANTATION; PRIORITY JOURNAL; RISK ASSESSMENT; SCHOOL CHILD;

ADOLESCENT; ADULT; AGED; CARCINOMA, HEPATOCELLULAR; CHILD; DISEASE-FREE SURVIVAL; DNA, VIRAL; FEMALE; HEPATITIS B VIRUS; HUMANS; KAPLAN-MEIER ESTIMATE; LIVER NEOPLASMS; LIVER TRANSPLANTATION; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PROPORTIONAL HAZARDS MODELS; RECURRENCE; RETROSPECTIVE STUDIES; RISK FACTORS; SENSITIVITY AND SPECIFICITY; VIRAL LOAD; YOUNG ADULT;

EID: 79955108233     PISSN: 00122823     EISSN: 14219867     Source Type: Journal    
DOI: 10.1159/000324197     Document Type: Article

References (22)

1. Kiyici M, Yilmaz M, Akyildiz M, Arikan C, Aydin U, Siqirli D, Nart D, Yilmaz F, Ozacar T, Karasu Z, Kilic M: Association between hepatitis B and hepatocellular carcinoma recurrence in patients undergoing liver transplantation. Transplant Proc 2008; 40: 1511-1517. (Pubitemid 351853237)
2. Mazzaferro V, Regalia E, Doci R, Andreola S, Pulvirenti A, Bozzetti F, Montalto F, Ammatuna M, Morabito A, Gennari L: Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N Engl J Med 1996; 334: 693-699. (Pubitemid 26079803)
3. Figueras J, Jaurrieta E, Valls C, Benasco C, Rafecas A, Xiol X, Fabregat J, Casanovas T, Torras J, Baliellas C, Ibanez L, Moreno P, Casais L: Survival after liver transplantation in cirrhotic patients with and without hepatocellular carcinoma: A comparative study. Hepatology 1997; 25: 1485-1489. (Pubitemid 27250773)
4. Molmenti EP, Klintmalm GB: Liver transplantation in association with hepatocellular carcinoma: An update of the International Tumor Registry. Liver Transpl 2002; 8: 736-748. (Pubitemid 35012281)
5. Shimoda M, Ghobrial RM, Carmody IC, Anselmo DM, Farmer DG, Yersiz H, Chen P, Dawson S, Durazo F, Han S, Goldstein LI, Saab S, Hiatt J, Busuttil RW: Predictors of survival after liver transplantation for hepatocellular carcinoma associated with hepatitis C. Liver Transpl 2004; 10: 1478-1486. (Pubitemid 40028380)
6. Yang HI, Lu SN, Liaw YF, You SL, Sun CA, Wang LY, Hsiao CK, Chen PJ, Chen DS, Chen CJ: Hepatitis B e antigen and the risk of hepatocellular carcinoma. N Engl J Med 2002; 347: 168-174. (Pubitemid 34764820)
7. Llovet JM, Bruix J: Novel advancements in the management of hepatocellular carcinoma in 2008. J Hepatol 2008; 48:S20-S37.
8. Ou DP, Yang LY, Huang GW, Tao YM, Ding X, Chang ZG: Clinical analysis of the risk factors for recurrence of HCC and its relationship with HBV. World J Gastroenterol 2005; 11: 2061-2066. (Pubitemid 40542647)
9. Kubo S, Hirohashi K, Tanaka H, Tsukamoto T, Shuto T, Yamamoto T, Ikebe T, Wakasa K, Nishiguchi S, Kinoshita H: Effect of viral status on recurrence after liver resection for patients with hepatitis B virus-related hepatocellular carcinoma. Cancer 2000; 88: 1016-1024. (Pubitemid 30127660)
10. Jiao ZY, Jiao Z: Prophylaxis of recurrent hepatitis B in Chinese patients after liver transplantation using lamivudine combined with hepatitis B immune globulin according to the titer of antibody to hepatitis B surface antigen. Transplant Proc 2007; 39: 1533-1536. (Pubitemid 46907920)
11. Yi NJ, Suh KS, Cho JY, Kwon CH, Lee KW, Joh JW, Lee SK, Kim SI, Lee KU: Recurrence of hepatitis B is associated with cumulative corticosteroid dose and chemotherapy against hepatocellular carcinoma recurrence after liver transplantation. Liver Transpl 2007; 13: 451-458. (Pubitemid 46444475)
12. Jang JW, Choi JY, Bae SH, Yoon SK, Woo HY, Chang UI, Kim CW, Nam SW, Cho SH, Yang JM, Lee CD: The impact of hepatitis B viral load on recurrence after complete necrosis in patients with hepatocellular carcinoma who receive transarterial chemolipiodolization. Cancer 2007; 110: 1760-1767.
13. Seehofer D, Berg T: Prevention of hepatitis B recurrence after liver transplantation. Transplantation 2005; 80:S120-S124. (Pubitemid 41552921)
14. Faria LC, Giqou M, Roque-Afonso A, Sebagh M, Roche B, Fallot G, Ferrari TC, Guettier C, Dussaix E, Castaing D, Brechot C, Samuel D: Hepatocellular carcinoma is associated with an increased risk of hepatitis B virus recurrence after liver transplantation. Gastroenterology 2008; 134: 1890-1899. (Pubitemid 351783254)
15. Schwartz M, Konstadoulakis M, Roayaie S: Recurrence of hepatocellular carcinoma after liver transplantation: Is immunosuppression a factor? Liver Transpl 2005; 11: 494-495.
16. Chen CJ, Yang HI, Su J, Jen CL, You SL, Lu SN, Huang GT, Iloeje UH: Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level. JAMA 2006; 295: 265-273.
17. Yuan HJ, Yuen MF, Ka-Ho Wong D, Sablon E, Lai CL: The relationship between HBVDNA levels and cirrhosis-related complications in Chinese with chronic hepatitis B. J Viral Hepat 2005; 12: 373-379. (Pubitemid 40961476)
18. Ishikawa H, Nakao K, Matsumoto K, Nishimura D, Ichikawa T, Hamasaki K, Eguchi K: Bone marrow engraftment in a rodent model of chemical carcinogenesis but no role in the histogenesis of hepatocellular carcinoma. Gut 2004; 53: 884-889. (Pubitemid 38662141)
19. Kubota K, Soeda J, Misawa R Mihara M, Miwa S, Ise H, Takahashi M, Miyagawa S: Bone marrow-derived cells fuse with hepatic oval cells but are not involved in hepatic tumorigenesis in the choline-deficient ethionine- supplemented diet rat model. Carcinogenesis 2008; 29: 448-454. (Pubitemid 351359687)
20. Zheng JF, Liang LJ: Transplanted bone marrow stromal cells are not cellular origin of hepatocellular carcinomas in a mouse model of carcinogenesis. World J Gastroenterol 2008; 14: 3015-3020.
21. Yang ZF, Ngai P, Ho DW Yu WC, Ng MN, Lau CK, Li ML, Tam KH, Lam CT, Poon RT, Fan ST: Identification of local and circulating cancer stem cells in human liver cancer. Hepatology 2008; 47: 919-928. (Pubitemid 351449683)
22. Zimmerman MA, Ghobrial RM, Tong MJ, Hiatt JR, Cameron AM, Busuttil RW: Antiviral prophylaxis and recurrence of hepatocellular carcinoma following liver transplantation in patients with hepatitis B. Transplant Proc 2007; 39: 3276-3280. (Pubitemid 350258646)