메뉴 건너뛰기




Volumn 72, Issue 5, 2010, Pages 546-556

Pharmacological review on Centella asiatica: A potential herbal cure-all

Author keywords

Centella asiatica; description; herb drug interactions; pharmacology of Centella asiatica; preclinical and clinical studies; side effects; therapeutic uses

Indexed keywords

4 AMINOBUTYRIC ACID; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; ANTIINFLAMMATORY AGENT; ANTINOCICEPTIVE AGENT; ANTIOXIDANT; ANTIULCER AGENT; ANXIOLYTIC AGENT; ASCORBIC ACID; CATALASE; CENTELLA ASIATICA EXTRACT; CHOLECYSTOKININ RECEPTOR; CORTICOSTERONE; DOPAMINE; GASTRIN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; NORADRENALIN; SEDATIVE AGENT; SEROTONIN; SUPEROXIDE DISMUTASE;

EID: 79955086328     PISSN: 0250474X     EISSN: 19983743     Source Type: Journal    
DOI: 10.4103/0250-474X.78519     Document Type: Review
Times cited : (445)

References (84)
  • 1
    • 0030716184 scopus 로고    scopus 로고
    • The status and scope of Indian medicinal plants acting on central nervous system
    • Vaidya AB. The status and scope of Indian medicinal plants acting on central nervous system. Indian J Pharmacol 1997;29:S340-3.
    • (1997) Indian J Pharmacol , vol.29
    • Vaidya, A.B.1
  • 2
    • 0033817663 scopus 로고    scopus 로고
    • Pharmacology of medicinal plants and natural products
    • Dahanukar SA, Kulkarni RA. Pharmacology of medicinal plants and natural products. Indian J Pharmacol 2000;32:S81-S118.
    • (2000) Indian J Pharmacol , vol.32
    • Dahanukar, S.A.1    Kulkarni, R.A.2
  • 3
    • 53449093803 scopus 로고    scopus 로고
    • Review on plants with CNS-effects used in traditional South African medicine against mental diseases
    • Stafford GI, Pedersen ME, van Staden J, Jäger AK. Review on plants with CNS-effects used in traditional South African medicine against mental diseases. J Ethnopharmacol 2008;119:513-37.
    • (2008) J Ethnopharmacol , vol.119 , pp. 513-537
    • Stafford, G.I.1    Pedersen, M.E.2    Van Staden, J.3    Jäger, A.K.4
  • 8
    • 0033772304 scopus 로고    scopus 로고
    • Chemical, pharmacological and clinical profi le of the East Asian medical plant Centella asiatica
    • Brinkhaus B, Lindner M, Schuppan D, Hahn EG. Chemical, pharmacological and clinical profi le of the East Asian medical plant Centella asiatica. Phytomedicine 2000;7:427-48.
    • (2000) Phytomedicine , vol.7 , pp. 427-448
    • Brinkhaus, B.1    Lindner, M.2    Schuppan, D.3    Hahn, E.G.4
  • 9
    • 0036166328 scopus 로고    scopus 로고
    • Recruitment and competitive interaction between ramets and seedlings in a perennial medicinal herb, Centella asiatica
    • Singh P, Singh JS. Recruitment and competitive interaction between ramets ans seedlings in a perennial medicinal herb, Centella asiatica. Basic Appl Ecol 2002;3:65-76. (Pubitemid 34140351)
    • (2002) Basic and Applied Ecology , vol.3 , Issue.1 , pp. 65-76
    • Singh, P.1    Singh, J.S.2
  • 10
    • 79955116922 scopus 로고    scopus 로고
    • PDR for herbal medicine. 1st ed. Montvale, NJ: Medical Economics Co
    • PDR for herbal medicine. 1st ed. Montvale, NJ: Medical Economics Co; 1999. p.729.
    • (1999) , pp. 729
  • 12
    • 0007188704 scopus 로고
    • Treatment of leprosy
    • Baily E. Treatment of leprosy. Nature 1945;155:601.
    • (1945) Nature , vol.155 , pp. 601
    • Baily, E.1
  • 13
    • 0007718866 scopus 로고
    • A reinvestigation of the triterpenes of Centella asiatica
    • Singh B, Rastogi RP. A reinvestigation of the triterpenes of Centella asiatica. Phytochem 1969;8:917-21.
    • (1969) Phytochem , vol.8 , pp. 917-921
    • Singh, B.1    Rastogi, R.P.2
  • 16
    • 0000046640 scopus 로고    scopus 로고
    • Chemistry and pharmacology of Centella asiatica: A review
    • Srivastava R, Shukla YN, Kumar S. Chemistry and pharmacology of Centella asiatica: a review. J Med Arom Plant Sci 1997;19:1049-56.
    • (1997) J Med Arom Plant Sci , vol.19 , pp. 1049-1056
    • Srivastava, R.1    Shukla, Y.N.2    Kumar, S.3
  • 17
    • 0032085495 scopus 로고    scopus 로고
    • Evaluation of topical formulations of aqueous extract of Centella asiatica on open wounds in rats
    • Sun ilkumar, Parameshwaraiah S, Shivakumar HG. Evaluation of topical formulations of aqueous extract of Centella asiatica on open wounds in rats. Indian J Exp Biol 1998;36:569-72.
    • (1998) Indian J Exp Biol , vol.36 , pp. 569-572
    • Kumar, S.1    Parameshwaraiah, S.2    Shivakumar, H.G.3
  • 18
    • 0018266964 scopus 로고
    • Modification of the kinetics of healing after iterative exeresis in the rat. Action of a triterpenoid and its derivatives on the duration of healing
    • Poi zot A, Dumez D. Modification of the kinetics of healing after iterative exeresis in the rat. Action of a triterpenoid and its derivatives on the duration of healing. C R Acad Sci Hebd Seances Acad Sci D 1978;286:789-92.
    • (1978) C R Acad Sci Hebd Seances Acad Sci D , vol.286 , pp. 789-792
    • Poizot, A.1    Dumez, D.2
  • 21
    • 0033059680 scopus 로고    scopus 로고
    • Asiaticoside-induced elevation of antioxidant levels in healing wounds
    • Shuk la A, Rasik AM, Dhawan BN. Asiaticoside-induced elevation of antioxidant levels in healing wounds. Phytother Res 1999;13:50-4. (Pubitemid 29092498)
    • (1999) Phytotherapy Research , vol.13 , Issue.1 , pp. 50-54
    • Shukla, A.1    Rasik, A.M.2    Dhawan, B.N.3
  • 22
    • 0029799760 scopus 로고    scopus 로고
    • Effects of Centella asiatica extract on dermal wound healing in rats
    • Suguna L, Sivakumar P, Chandrakasan G. Effects of Centella asiatica extract on dermal wound healing in rats. Indian J Exp Biol 1996;34:1208-11.
    • (1996) Indian J Exp Biol , vol.34 , pp. 1208-1211
    • Suguna, L.1    Sivakumar, P.2    Chandrakasan, G.3
  • 23
    • 0032938834 scopus 로고    scopus 로고
    • In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica
    • DOI 10.1016/S0378-8741(98)00141-X, PII S037887419800141X
    • Shukla A, Rasik AM, Jain GK, Shankar R, Kulshrestha DK, Dhawan BN. In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica. J Ethnopharmacol 1999;65:1-11. (Pubitemid 29193059)
    • (1999) Journal of Ethnopharmacology , vol.65 , Issue.1 , pp. 1-11
    • Shukla, A.1    Rasik, A.M.2    Jain, G.K.3    Shankar, R.4    Kulshrestha, D.K.5    Dhawan, B.N.6
  • 24
    • 0019807332 scopus 로고
    • Comparative Capillaroscopic study of certain biofl avonoids and total triterpenic fractions of Centella asiatica in venous insuffi ciency
    • Alle gra C. Comparative Capillaroscopic study of certain biofl avonoids and total triterpenic fractions of Centella asiatica in venous insuffi ciency. Clin Ther 1981;99:507-13.
    • (1981) Clin Ther , vol.99 , pp. 507-513
    • Allegra, C.1
  • 25
    • 0018597068 scopus 로고
    • NOTE SUR L'UTILISATION DE L'EXTRAIT TITRE DE CENTELLA ASIATICA AU COURS DES HEPATOPATHIES CHRONIQUES
    • Darn is F, Orcel L, de Saint-Maur PP, Mamou P. Use of a titrated extract of Centella asiatica in chronic hepatic disorders. Sem Hop 1979;55:1749-50. (Pubitemid 10126792)
    • (1979) Semaine des Hopitaux , vol.55 , Issue.37-38 , pp. 1749-1750
    • Darnis, F.1    Orcel, L.2    De Saint-Maur, P.P.3    Mamou, P.4
  • 27
    • 0036167343 scopus 로고    scopus 로고
    • Effect of different extracts of Centella asiatica on cognition and markers of oxidative stress in rats
    • DOI 10.1016/S0378-8741(01)00394-4, PII S0378874101003944
    • Veerendra Kumar MH, Gupta YK. Effect of different extracts of Centella asiatica on cognition and markers of oxidative stress in rats. J Ethnopharmacol 2002;79:253-60. (Pubitemid 34136958)
    • (2002) Journal of Ethnopharmacology , vol.79 , Issue.2 , pp. 253-260
    • Veerendra Kumar, M.H.1    Gupta, Y.K.2
  • 29
    • 2342636313 scopus 로고    scopus 로고
    • Effect of total triterpenes from Centella asiatica on the depression behaviour and concentration of amino acid in forced swimming mice
    • Che n Y, Han T, Qin L, Rui Y, Zheng H. Effect of total triterpenes from Centella asiatica on the depression behaviour and concentration of amino acid in forced swimming mice. Zhong Yao Cai 2003;26:870-3.
    • (2003) Zhong Yao Cai , vol.26 , pp. 870-873
    • Chen, Y.1    Han, T.2    Qin, L.3    Rui, Y.4    Zheng, H.5
  • 30
    • 33747222106 scopus 로고    scopus 로고
    • Effects of total triterpenes of Centella asiatica on the corticosterone levels in serum and contents of monoamine in depression rat brain
    • Chen Y, Han T, Rui Y, Yin M, Qin L, Zheng H. Effects of total triterpenes of Centella asiatica on the corticosterone levels in serum and contents of monoamine in depression rat brain. Zhong Yao Cai 2005;28:492-6.
    • (2005) Zhong Yao Cai , vol.28 , pp. 492-496
    • Chen, Y.1    Han, T.2    Rui, Y.3    Yin, M.4    Qin, L.5    Zheng, H.6
  • 31
    • 0027501415 scopus 로고
    • Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer
    • Hausen BM. Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer. Contact Dermatitis 1993;29:175-9. (Pubitemid 23290839)
    • (1993) Contact Dermatitis , vol.29 , Issue.4 , pp. 175-179
    • Hausen, B.M.1
  • 32
    • 0037304282 scopus 로고    scopus 로고
    • Effect of Centella asiatica on pentylenetetrazole-induced kindling, cognition and oxidative stress in rats
    • DOI 10.1016/S0091-3057(02)01044-4, PII S0091305702010444
    • Gupta YK, Veerendra Kumar MH, Srivastava AK. Effect of Centella asiatica on pentylenetetrazole-induced kindling, cognition and oxidative stress in rats. Pharmacol Biochem Behav 2003;74:579-85. (Pubitemid 36126535)
    • (2003) Pharmacology Biochemistry and Behavior , vol.74 , Issue.3 , pp. 579-585
    • Gupta, Y.K.1    Veerendra Kumar, M.H.2    Srivastava, A.K.3
  • 33
    • 10044251226 scopus 로고    scopus 로고
    • Neuropharmacology of an extract derived from Centella asiatica
    • DOI 10.1080/13880200490514177
    • Ganachari MS, Babu V, Katare S. Neuropharmacology of an extract derived from Centella asiatica. Pharm Biol 2004;42:246-52. (Pubitemid 39611769)
    • (2004) Pharmaceutical Biology , vol.42 , Issue.3 , pp. 246-252
    • Ganachari, M.S.1    Veeresh Babu, S.V.2    Katare, S.S.3
  • 34
    • 0038809806 scopus 로고    scopus 로고
    • Effect of Centella asiatica on cognition and oxidative stress in an intracerebroventricular streptozotocin model of Alzheimer's disease in rats
    • DOI 10.1046/j.1440-1681.2003.03842.x
    • Veerendra Kumar MH, Gupta YK. Effect of Centella asiatica on cognition and oxidative stress in an intracerebroventricular streptozotocin model of Alzheimer's disease in rats. Clin Exp Pharmacol Physiol 2003;30:336-42. (Pubitemid 36713989)
    • (2003) Clinical and Experimental Pharmacology and Physiology , vol.30 , Issue.5-6 , pp. 336-342
    • Veerendra Kumar, M.H.1    Gupta, Y.K.2
  • 35
    • 47849084488 scopus 로고    scopus 로고
    • Gotu Kola (Centella Asiatica) extract enhances phosphorylation of cyclic AMP response element binding protein in neuroblastoma cells expressing amyloid beta peptide
    • Xu Y, Cao Z, Khan I, Luo Y. Gotu Kola (Centella asiatica) extract enhances phosphorylation of cyclic AMP response element binding protein in neuroblastoma cells expressing amyloid beta peptide. J Alzheimers Dis 2008;13:341-9. (Pubitemid 352039032)
    • (2008) Journal of Alzheimer's Disease , vol.13 , Issue.3 , pp. 341-349
    • Xu, Y.1    Cao, Z.2    Khan, I.3    Luo, Y.4
  • 36
    • 0038052884 scopus 로고    scopus 로고
    • Anti-oxidant activity of Centella asiatica on lymphoma-bearing mice
    • DOI 10.1016/S0367-326X(03)00121-7
    • Jayashree G, Kurup Muraleedhara G, Sudarslal S, Jacob VB. Antioxidant activity of Centella asiatica on lymphoma-bearing mice. Fitoterapia 2003;74:431-4. (Pubitemid 36805624)
    • (2003) Fitoterapia , vol.74 , Issue.5 , pp. 431-434
    • Jayashree, G.1    Kurup Muraleedhara, G.2    Sudarslal, S.3    Jacob, V.B.4
  • 39
    • 0034644721 scopus 로고    scopus 로고
    • Effects of Centella asiatica on ethanol induced gastric mucosal lesions in rats
    • Cheng CL, Koo MW. Effects of Centella asiatica on ethanol induced gastric mucosal lesions in rats. Life Sci 2000;67:2647-53.
    • (2000) Life Sci , vol.67 , pp. 2647-2653
    • Cheng, C.L.1    Koo, M.W.2
  • 40
    • 0026713390 scopus 로고
    • Effects of plant extract Centella asiatica (Linn.) on cold restraint stress ulcer in rats
    • Chatterjee TK, Chakraborty A, Pathak M, Sengupta GC. Effects of plant extract Centella asiatica (Linn.) on cold restraint stress ulcer in rats. Indian J Exp Biol 1992;30:889-91.
    • (1992) Indian J Exp Biol , vol.30 , pp. 889-891
    • Chatterjee, T.K.1    Chakraborty, A.2    Pathak, M.3    Sengupta, G.C.4
  • 41
    • 0020052857 scopus 로고
    • γ-Aminobutyric acid (GABA) receptor stimulation. IV. Effect of progabide (SL 76002) and other GABAergic agents on acetylcholine turnover in rat brain areas
    • Scatton B, Bartholini G. Gamma-aminobutyric acid (GABA) receptor stimulation. IV. Effect of progabide (SL 76002) and other GABAergic agents on acetylcholine turnover in rat brain areas. J Pharmacol Exp Ther 1982;220:689-95. (Pubitemid 12152188)
    • (1982) Journal of Pharmacology and Experimental Therapeutics , vol.220 , Issue.3 , pp. 689-695
    • Scatton, B.1    Bartholini, G.2
  • 42
    • 0035112251 scopus 로고    scopus 로고
    • Effect of Centella asiatica Linn on physical and chemical factors induced gastric ulceration and secretion in rats
    • Sairam K, Rao CV, Goel RK. Effect of Centella asiatica Linn on physical and chemical factors induced gastric ulceration and secretion in rats. Indian J Exp Biol 2001;39:137-42. (Pubitemid 32183936)
    • (2001) Indian Journal of Experimental Biology , vol.39 , Issue.2 , pp. 137-142
    • Sairam, K.1    Rao, Ch.V.2    Goel, R.K.3
  • 43
    • 11944255357 scopus 로고    scopus 로고
    • Inhibitory effects of Centella asiatica water extract and asiaticoside on inducible nitric oxide synthase during gastric ulcer healing in rats
    • DOI 10.1055/s-2004-835843
    • Guo JS, Cheng CL, Koo MW. Inhibitory effects of Centella asiatica water extract and asiaticoside on inducible nitric oxide synthase during gastric ulcer healing in rats. Planta Med 2004;70:1150-4. (Pubitemid 40101095)
    • (2004) Planta Medica , vol.70 , Issue.12 , pp. 1150-1154
    • Jin, S.G.1    Chuen, L.C.2    Koo, M.W.L.3
  • 44
    • 1342281647 scopus 로고    scopus 로고
    • The healing effects of Centella extract and asiaticoside on acetic acid induced gastric ulcers in rats
    • DOI 10.1016/j.lfs.2003.09.055
    • Cheng CL, Guo JS, Luk J, Koo MW. The healing effects of Centella extract and asiaticoside on acetic acid induced gastric ulcers in rats. Life Sci 2004;74:2237-49. (Pubitemid 38249545)
    • (2004) Life Sciences , vol.74 , Issue.18 , pp. 2237-2249
    • Cheng, C.L.1    Guo, J.S.2    Luk, J.3    Koo, M.W.L.4
  • 45
    • 0002913809 scopus 로고
    • Clinical trials of madecassol (Centella asiatica) on gastrointestinal ulcer patients
    • Shin HS. Clinical trials of madecassol (Centella asiatica) on gastrointestinal ulcer patients. Korean J Gastroenterol 1982;14:49-56.
    • (1982) Korean J Gastroenterol , vol.14 , pp. 49-56
    • Shin, H.S.1
  • 46
    • 0010268014 scopus 로고
    • Clinical effect of the titrated extract of Centella asiatica (madecassol) on peptic ulcer
    • Rhee JC, Choi KW. Clinical effect of the titrated extract of Centella asiatica (madecassol) on peptic ulcer. Korean J Gastroenterol 1981;13:35-40.
    • (1981) Korean J Gastroenterol , vol.13 , pp. 35-40
    • Rhee, J.C.1    Choi, K.W.2
  • 47
    • 12544257143 scopus 로고
    • Clinical experiences of madecassol (Centella asiatica) in the treatment of peptic ulcer
    • Cho KH. Clinical experiences of madecassol (Centella asiatica) in the treatment of peptic ulcer. Korean J Gastroenterol 1981;13:49-56.
    • (1981) Korean J Gastroenterol , vol.13 , pp. 49-56
    • Cho, K.H.1
  • 48
    • 23244441701 scopus 로고    scopus 로고
    • Adjunctive periodontal treatment with Centella asiatica and Punica granatum extracts in supportive periodontal therapy
    • Sastravaha G, Gassmann G, Sangtherapitikul P, Grimm WD. Adjunctive periodontal treatment with Centella asiatica and Punica granatum extracts in supportive periodontal therapy. J Int Acad Periodontol 2005;7:70-9.
    • (2005) J Int Acad Periodontol , vol.7 , pp. 70-79
    • Sastravaha, G.1    Gassmann, G.2    Sangtherapitikul, P.3    Grimm, W.D.4
  • 51
    • 51749100609 scopus 로고    scopus 로고
    • Anti-rheumatoid arthritic effect of madecassoside on type II collagen-induced arthritis in mice
    • Liu M, Dai Y, Yao X, Li Y, Luo Y, Xia Y, et al. Anti-rheumatoid arthritic effect of madecassoside on type II collagen-induced arthritis in mice. Int Immunopharmacol 2008;8:1561-6.
    • (2008) Int Immunopharmacol , vol.8 , pp. 1561-1566
    • Liu, M.1    Dai, Y.2    Yao, X.3    Li, Y.4    Luo, Y.5    Xia, Y.6
  • 52
    • 0036886108 scopus 로고    scopus 로고
    • Radioprotection of Swiss Albino Mouse by Centella asiatica Extract
    • DOI 10.1002/ptr.1069
    • Sharma J, Sharma R. Radioprotection of Swiss albino mouse by Centella asiatica extract. Phytother Res 2002;16:785-6. (Pubitemid 135752595)
    • (2002) Phytotherapy Research , vol.16 , Issue.8 , pp. 785-786
    • Sharma, J.1    Sharma, R.2
  • 53
    • 0034993746 scopus 로고    scopus 로고
    • Protection against radiation-induced conditioned taste aversion by Centella asiatica
    • DOI 10.1016/S0031-9384(01)00434-6, PII S0031938401004346
    • Shobi V, Goel HC. Protection against radiation-induced conditioned taste aversion by Centella asiatica. Physiol Behav 2001;73:19-23. (Pubitemid 32530536)
    • (2001) Physiology and Behavior , vol.73 , Issue.1-2 , pp. 19-23
    • Shobi, V.1    Goel, H.C.2
  • 54
    • 0033631831 scopus 로고    scopus 로고
    • Antiherpes Simplex Virus activities of crude water extracts of Thai medicinal plants
    • Yooso ok C, Bunyapraphatsara N, Boonyakiat Y, Kantasuk C. Antiherpes Simplex Virus activities of crude water extracts of Thai medicinal plants. Phytomedicine 2000;6:411-9.
    • (2000) Phytomedicine , vol.6 , pp. 411-419
    • Yoosook, C.1    Bunyapraphatsara, N.2    Boonyakiat, Y.3    Kantasuk, C.4
  • 55
    • 0024676012 scopus 로고
    • An experimental study of the anti-HSV-II action of 500 herbal drugs
    • Zheng MS. An experimental study of the anti-HSV-II action of 500 herbal drugs. J Tradit Chin Med 1989;9:113-6.
    • (1989) J Tradit Chin Med , vol.9 , pp. 113-116
    • Zheng, M.S.1
  • 56
    • 0029082077 scopus 로고
    • Cytotoxic and anti-tumor properties of certain taxa of Umbelliferae with special reference to Centella asiatica (L.) Urban
    • Babu TD, Kuttan G, Padikkala J. Cytotoxic and anti-tumor properties of certain taxa of Umbelliferae with special reference to Centella asiatica (L.) Urban. J Ethnopharmacol 1995;48:50-7.
    • (1995) J Ethnopharmacol , vol.48 , pp. 50-57
    • Babu, T.D.1    Kuttan, G.2    Padikkala, J.3
  • 57
    • 0031061238 scopus 로고    scopus 로고
    • In vitro evaluation of inhibitory nature of extracts of 18-plant species of Chhindwara against 3-keratinophilic fungi
    • Qureshi S, Rai MK, Agrawal SC. In vitro evaluation of inhibitory nature of extracts of 18-plant species of Chhindwara against 3-keratinophilic fungi. Hindustan Antibiot Bull 1997;39:56-60.
    • (1997) Hindustan Antibiot Bull , vol.39 , pp. 56-60
    • Qureshi, S.1    Rai, M.K.2    Agrawal, S.C.3
  • 58
    • 0033122264 scopus 로고    scopus 로고
    • Dietary supplements used in the treatment of depression, anxiety, and sleep disorders
    • Cauffi eld JS, Forbes HJ. Dietary supplements used in the treatment of depression, anxiety, and sleep disorders. Lippincotts Prim Care Pract 1999;3:290-304.
    • (1999) Lippincotts Prim Care Pract , vol.3 , pp. 290-304
    • Cauffield, J.S.1    Forbes, H.J.2
  • 59
    • 0023974550 scopus 로고
    • Effect of the triterpenoid fraction of Centella asiatica on macromolecules of the connective matrix in human skin fibroblast cultures
    • Tenni R, Zanaboni G, De Agostini MP, Rossi A, Bendotti C, Cetta G. Effect of the triterpenoid fraction of Centella asiatica on macromolecules of the connective matrix in human skin fibroblast cultures. Ital J Biochem 1988;37:69-77.
    • (1988) Ital J Biochem , vol.37 , pp. 69-77
    • Tenni, R.1    Zanaboni, G.2    De Agostini, M.P.3    Rossi, A.4    Bendotti, C.5    Cetta, G.6
  • 60
    • 0025038171 scopus 로고
    • Stimulation of collagen synthesis in fibroblast cultures by a triterpene extracted from Centella asiatica
    • Maquart FX, Bellon G, Gillery P, Wegrowski Y, Borel JP. Stimulation of collagen synthesis in fi broblast cultures by a triterpene extracted from Centella asiatica. Connect Tissue Res 1990;24:107-20.
    • (1990) Connect Tissue Res , vol.24 , pp. 107-120
    • Maquart, F.X.1    Bellon, G.2    Gillery, P.3    Wegrowski, Y.4    Borel, J.P.5
  • 61
    • 0033059680 scopus 로고    scopus 로고
    • Asiaticoside-induced elevation of antioxidant levels in healing wounds
    • Shukla A, Rasik AM, Dhawan BN. Asiaticoside-induced elevation of antioxidant levels in healing wounds. Phytother Res 1999;13:50-4. (Pubitemid 29092498)
    • (1999) Phytotherapy Research , vol.13 , Issue.1 , pp. 50-54
    • Shukla, A.1    Rasik, A.M.2    Dhawan, B.N.3
  • 62
    • 0032938834 scopus 로고    scopus 로고
    • In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica
    • DOI 10.1016/S0378-8741(98)00141-X, PII S037887419800141X
    • Shukla A, Rasik AM, Jain GK, Shankar R, Kulshrestha DK, Dhawan BN. In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica. J Ethnopharmacol 1999;65:1-11. (Pubitemid 29193059)
    • (1999) Journal of Ethnopharmacology , vol.65 , Issue.1 , pp. 1-11
    • Shukla, A.1    Rasik, A.M.2    Jain, G.K.3    Shankar, R.4    Kulshrestha, D.K.5    Dhawan, B.N.6
  • 63
    • 0025800528 scopus 로고
    • Centella asiatica triterpenic fraction (CATTF) reduces the number of circulating endothelial cells in subjects with post phlebetic syndrome
    • Montecchio GP, Samaden A, Carbone S, Vigotti M, Siragusa S, Piovella F. Centella asiatica triterpenic fraction (CATTF) reduces the number of circulating endothelial cells in subjects with post phlebetic syndrome. Haematologica 1991;76:256-9.
    • (1991) Haematologica , vol.76 , pp. 256-259
    • Montecchio, G.P.1    Samaden, A.2    Carbone, S.3    Vigotti, M.4    Siragusa, S.5    Piovella, F.6
  • 64
    • 0023126631 scopus 로고
    • Titrated extract of centella asiatica (TECA) in the treatment of venous insufficiency of the lower limbs
    • Pointel JP, Boccalon H, Cloarec M. Ledevehat C, Joubert M. Titrated extract of Centella asiatica (TECA) in the treatment of venous insuffi ciency of the lower limbs. Angiology 1987;38:46-50. (Pubitemid 17029148)
    • (1987) Angiology , vol.38 , Issue.1 , pp. 46-50
    • Pointel, J.P.1    Boccalon, H.2    Cloarec, M.3
  • 65
    • 0025115294 scopus 로고
    • Capillary filtration and ankle edema in patients with venous hypertension treated with TTFCA
    • Belcaro GV, Rulo A, Grimaldi R. Capillary fi ltration and ankle edema in patients with venous hypertension treated with TTFCA. Angiology 1990;41:12-8. (Pubitemid 20067112)
    • (1990) Angiology , vol.41 , Issue.1 , pp. 12-18
    • Belcaro, G.V.1    Rulo, A.2    Grimaldi, R.3
  • 68
    • 0024997628 scopus 로고
    • Improvement of capillary permeability in patients with venous hypertension after treatment with TTFCA
    • Belca ro GV, Grimaldi R, Guidi G. Improvement of capillary permeability in patients with venous hypertension after treatment with TTFCA. Angiology 1990;41:533-40. (Pubitemid 20263007)
    • (1990) Angiology , vol.41 , Issue.7 , pp. 533-540
    • Belcaro, G.V.1    Grimaldi, R.2    Guidi, G.3
  • 70
    • 79955114995 scopus 로고    scopus 로고
    • Creams for preventing stretch marks in pregnancy, (Review)
    • New York. John Wiley and Sons Ltd
    • Young GL, Jewell D. Creams for preventing stretch marks in pregnancy. (Review). The Cochrane Collaboration. New York. John Wiley and Sons Ltd; 2005. p. 1-7.
    • (2005) The Cochrane Collaboration , pp. 1-7
    • Young, G.L.1    Jewell, D.2
  • 72
    • 35748962334 scopus 로고    scopus 로고
    • A randomized, double-blind, vehicle-controlled, half-side comparison with a herbal ointment containing Mahonia aquifolium, Viola tricolor and Centella asiatica for the treatment of mild-to-moderate atopic dermatitis
    • Klovekorn W, Tepe A, Danesch UA. A randomized, double-blind, vehicle-controlled, half-side comparison with a herbal ointment containing Mahonia aquifolium, Viola tricolor and Centella asiatica for the treatment of mild-to-moderate atopic dermatitis. Int J Clin Pharmacol Ther 2007;45:583-91. (Pubitemid 350047752)
    • (2007) International Journal of Clinical Pharmacology and Therapeutics , vol.45 , Issue.11 , pp. 583-591
    • Klovekorn, W.1    Tepe, A.2    Danesch, U.3
  • 73
    • 39149108464 scopus 로고    scopus 로고
    • Positive modulation of cognition and mood in the healthy elderly volunteer following the administration of Centella asiatica
    • Wattanathorn J, Mator L, Muchimapura S, Tongun T, Pasuriwong O, Piyawatkul N, et al. Positive modulation of cognition and mood in the healthy elderly volunteer following the administration of Centella asiatica. J Ethnopharmacol 2008;116:325-32.
    • (2008) J Ethnopharmacol , vol.116 , pp. 325-332
    • Wattanathorn, J.1    Mator, L.2    Muchimapura, S.3    Tongun, T.4    Pasuriwong, O.5    Piyawatkul, N.6
  • 74
    • 0033725187 scopus 로고    scopus 로고
    • A Double-blind, Placebocontrolled Study on the Effects of Gotu Kola (Centella asiatica) on acoustic startle response in healthy subjects
    • Bradw ejn J, Zhou Y, Koszycki D, Shlik JA. A Double-blind, Placebocontrolled Study on the Effects of Gotu Kola (Centella asiatica) on acoustic startle response in healthy subjects. J Clin Psychopharmacol 2000;20:680-4.
    • (2000) J Clin Psychopharmacol , vol.20 , pp. 680-684
    • Bradwejn, J.1    Zhou, Y.2    Koszycki, D.3    Shlik, J.A.4
  • 75
    • 79952483282 scopus 로고    scopus 로고
    • Effect of Centella asiatica on mild cognitive impairment (MCI) and other common age-related clinical problems
    • Tiwari S, Singh S, Patwardhan K, Gehlot S, Gambhir IS. Effect of Centella asiatica on mild cognitive impairment (MCI) and other common age-related clinical problems. Digest J Nanomat Biostruct 2008;3:215-20.
    • (2008) Digest J Nanomat Biostruct , vol.3 , pp. 215-220
    • Tiwari, S.1    Singh, S.2    Patwardhan, K.3    Gehlot, S.4    Gambhir, I.S.5
  • 76
    • 0022383180 scopus 로고
    • Contact dermatitis due to madecassol
    • Eun HC, Lee AY. Contact dermatitis due to madecassol. Contact Dermatitis 1985;13:310-3.
    • (1985) Contact Dermatitis , vol.13 , pp. 310-313
    • Eun, H.C.1    Lee, A.Y.2
  • 77
    • 0014303967 scopus 로고
    • Crude extract of Centella asiatica and products derived from its glycosides as oral antiferility agents
    • Dutta T, Basu UP. Crude extract of Centella asiatica and products derived from its glycosides as oral antiferility agents. Indian J Exp Biol 1968;6:181.
    • (1968) Indian J Exp Biol , vol.6 , pp. 181
    • Dutta, T.1    Basu, U.P.2
  • 78
    • 0025257207 scopus 로고
    • Pharmacokinetics of the total triterpenic fraction of Centella asiatica after single and multiple administrations to healthy volunteers. A new assay for asiatic acid
    • Grimaldi R, De Ponti F, D'Ángelo L, Caravaggi M, Guidi G, Lecchini S, et al. Pharmacokinetics of the total triterpenic fraction of Centella asiatica after single and multiple administrations to healthy volunteers. A new assay for asiatic acid. J Ethnopharmacol 1990;28:235-41. (Pubitemid 20086041)
    • (1990) Journal of Ethnopharmacology , vol.28 , Issue.2 , pp. 235-241
    • Grimaldi, R.1    De Ponti, F.2    D'Angelo, L.3    Caravaggi, M.4    Guidi, G.5    Lecchini, S.6    Frigo, G.M.7    Crema, A.8
  • 80
    • 79955110020 scopus 로고    scopus 로고
    • No author listed, consulted on 2008 May 12
    • No author listed. Centella: Monographs for herbal medicinal products. 2007. available from:http://www.mohp.gov.eg/Sec/Statistics/hplants.pdf. [consulted on 2008 May 12].
    • (2007) Centella: Monographs for Herbal Medicinal Products
  • 82
    • 79955080454 scopus 로고    scopus 로고
    • No author listed, National Center for Complementary and Alternative Medicine (NCCAM), Oregon Health and Science University, Portland, Oregon, United States, Food and Drug Administration, Clinical trials.gov identifier: NCT00608439, cited on 2010 jul 28
    • No author listed. Centella asiatica selected triterpenes (CAST) for Diabetic Neuropathy. National Center for Complementary and Alternative Medicine (NCCAM), Oregon Health and Science University, Portland, Oregon, United States, Food and Drug Administration, 2010. Clinical trials.gov identifier: NCT00608439 available from: http:// clinicaltrials.gov/ct2/show/NCT00608439 [cited on 2010 jul 28].
    • (2010) Centella Asiatica Selected Triterpenes (CAST) for Diabetic Neuropathy
  • 83
    • 77955202727 scopus 로고    scopus 로고
    • Neuroprotective effects of Centella asiatica against intracerebroventricular colchicine induced cognitive impairment and oxidative stress
    • Kumar A, Dogra S, Prakash A. Neuroprotective effects of Centella asiatica against intracerebroventricular colchicine induced cognitive impairment and oxidative stress. Int J Alzheimers Dis 2009;2009:1-8.
    • (2009) Int J Alzheimers Dis 2009 , pp. 1-8
    • Kumar, A.1    Dogra, S.2    Prakash, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.