Suicide in a large population of former psychiatric inpatients

Psychiatry and Clinical Neurosciences

Volumn 65, Issue 3, 2011, Pages 286-295

  Sani, Gabriele ^a,b   Tondo, Leonardo ^a,c,d   Koukopoulos, Athanasios ^a   Reginaldi, Daniela ^a   Kotzalidis, Giorgio D ^b   Koukopoulos, Alexia E ^a,b   Manfredi, Giovanni ^a,b   Mazzarini, Lorenzo ^b,d   Pacchiarotti, Isabella ^b,d   Simonetti, Alessio ^a,b   Ambrosi, Elisa ^b   Angeletti, Gloria ^b   Girardi, Paolo ^a,b   Tatarelli, Roberto ^b  

^a Centro Lucio Bini   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d HOSPITAL CLÍNIC   (Spain)

Author keywords

agitation; antidepressant drugs; bipolar disorder; schizophrenia; suicide

Indexed keywords

ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; LITHIUM; MOOD STABILIZER; NEUROLEPTIC AGENT;

ADULT; AGITATION; ANXIETY DISORDER; ARTICLE; BIPOLAR DISORDER; CYCLOTHYMIA; DISEASE COURSE; FEMALE; FOLLOW UP; HIGH RISK POPULATION; HOSPITAL PATIENT; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MENTAL PATIENT; RISK FACTOR; SUICIDAL IDEATION; SUICIDE; SUICIDE ATTEMPT; SYMPTOMATOLOGY;

ADULT; FEMALE; HUMANS; INPATIENTS; MALE; MENTAL DISORDERS; PSYCHIATRIC STATUS RATING SCALES; PSYCHOTROPIC DRUGS; RETROSPECTIVE STUDIES; RISK FACTORS; SEX CHARACTERISTICS; SUICIDE;

EID: 79955058547     PISSN: 13231316     EISSN: 14401819     Source Type: Journal    
DOI: 10.1111/j.1440-1819.2011.02205.x     Document Type: Article

References (57)

1. World Health Organization. World Health Report 2003: Shaping the Future. World Health Organization, Geneva, 2003.
2. World Health Organization. Prevention of Mental Disorders. Effective Interventions and Policy Options. World Health Organization, Geneva, 2004; 49-51.
3. World Health Organization. Country Reports and Charts. World Health Organization, Geneva, 2007.
4. th, 2008). Rome, Italy: Istituto Nazionale di Statistica (National Institute of Statistics), 2009.
5. Nock MK, Borges G, Bromet EJ, Cha CB, Kessler RC, Lee S,. Suicide and suicidal behavior. Epidemiol. Rev. 2008; 30: 133-154.
6. Rihmer Z,. Suicide risk in mood disorders. Curr. Opin. Psychiatry 2007; 20: 17-22. (Pubitemid 44901071)
7. Baldessarini RJ, Tondo L,. Suicide risk and treatments for patients with bipolar disorder. JAMA 2003; 290: 1517-1519. (Pubitemid 37430410)
8. Baldessarini RJ, Tondo L, Hennen J,. Lithium treatment and suicide risk in major affective disorders: update and new findings. J. Clin. Psychiatry 2003; 64 (Suppl. 5): 44-52. (Pubitemid 36539131)
9. Baldessarini RJ, Tondo L, Davis P, Pompili M, Goodwin FK, Hennen J,. Decreased risk of suicides and attempts during long-term lithium treatment: a meta-analytic review. Bipolar Disord. 2006; 8: 625-639. (Pubitemid 44567144)
10. Goodwin FK, Fireman B, Simon GE, Hunkeler EM, Lee J, Revicki D,. Suicide risk in bipolar disorder during treatment with lithium and divalproex. JAMA 2003; 290: 1467-1473. (Pubitemid 37430401)
11. Tondo L, Baldessarini RJ, Hennen J, Floris G, Silvetti F, Tohen M,. Lithium treatment and risk of suicidal behavior in bipolar disorder patients. J. Clin. Psychiatry 1998; 59: 405-414. (Pubitemid 28391562)
12. Tondo L, Hennen J, Baldessarini RJ,. Lower suicide risk with long-term lithium treatment in major affective illness: a meta-analysis. Acta Psychiatr. Scand. 2001; 104: 163-172. (Pubitemid 32762270)
13. Meltzer HY, Alphs L, Green AI, et al,. Clozapine treatment for suicidality in schizophrenia: International Suicide Prevention Trial (InterSePT). Arch. Gen. Psychiatry 2003; 60: 82-91. [erratum 735]. (Pubitemid 36070868)
14. Ahrens B, Müller-Oerlinghausen B,. Does lithium exert an independent antisuicidal effect? Pharmacopsychiatry 2001; 34: 132-136. (Pubitemid 32701762)
15. Müller-Oerlinghausen B,. Arguments for the specificity of the antisuicidal effect of lithium. Eur. Arch. Psychiatry Clin. Neurosci. 2001; 251 (Suppl. 2): II72-II75.
16. Guzzetta F, Tondo L, Centorrino F, Baldessarini RJ,. Lithium treatment reduces suicide risk in recurrent major depressive disorder. J. Clin. Psychiatry 2007; 68: 380-383. (Pubitemid 46506801)
17. Reid WH, Mason M, Hogan T,. Suicide prevention effects associated with clozapine therapy in schizophrenia and schizoaffective disorder. Psychiatr. Serv. 1989; 49: 1029-1033.
18. Hennen J, Baldessarini RJ,. Suicidal risk during treatment with clozapine: a meta-analysis. Schizophr. Res. 2005; 73: 139-145. (Pubitemid 40103558)
19. Munro J, O'Sullivan D, Andrews C, Arana A, Mortimer A, Kerwin R,. Active monitoring of 12,760 clozapine recipients in the UK and Ireland. Beyond pharmacovigilance. Br. J. Psychiatry 1999; 175: 576-580.
20. Haas SJ, Dennekamp MN, Wolfe R, Vos T,. Beware the meta-analysis- clozapine and suicidal ideation. Schizophr. Res. 2006; 86: 331-332. (Pubitemid 44251279)
21. Kielholz P, Battegay R,. Treatment of depressive states with special consideration of tofranil, a new antidepressant. Schweiz. Med. Wochenschr. 1958; 88: 763-767.
22. Schneeweiss S, Patrick AR, Solomon DH, et al,. Variation in the risk of suicide attempts and completed suicides by antidepressant agent in adults: a propensity score-adjusted analysis of 9 years' data. Arch. Gen. Psychiatry 2010; 67: 497-506.
23. Stone M, Laughren T, Jones ML, et al,. Risk of suicidality in clinical trials of antidepressants in adults: analysis of proprietary data submitted to US Food and Drug Administration. BMJ 2009; 339: b2880.
24. Mann JJ, Emslie G, Baldessarini RJ, et al,. ACNP Task Force Report on SSRIs and suicidal behavior in youth. Neuropsychopharmacology 2006; 31: 473-492. (Pubitemid 43276964)
25. Isacsson G, Rich CL, Jureidini J, Raven M,. The increased use of antidepressants has contributed to the worldwide reduction in suicide rates. Br. J. Psychiatry 2010; 196: 429-433.
26. Wernicke JF, Sayler ME, Koke SC, Pearson DK, Tollefson GD,. Fluoxetine and concomitant centrally acting medication use during clinical trials of depression: the absence of an effect related to agitation and suicidal behavior. Depress. Anxiety 1997; 6: 31-39. (Pubitemid 28079909)
27. Kenchadze VG, Chkonia ED, Sikharulidze GG,. Increased risk of suicide in patients with agitated depression. Georgian Med. News 2009; 177: 47-51 (in Russian).
28. Greenberger D, Padesky CA,. Mind Over Mood. Guilford Press, New York, 1995.
29. Spitzer RL, Endicott J, Robins E,. Research Diagnostic Criteria (RDC). Biometrics Research Evaluation Center, New York State Psychiatric Institute, New York, 1975.
30. th Edition-Text Revision (DSM-IV-TR). American Psychiatric Association, Washington, DC, 2000.
31. Benazzi F,. Agitated depression: a valid depression subtype? Prog. Neuropsychopharmacol. Biol. Psychiatry 2004; 28: 1279-1285. (Pubitemid 39592925)
32. Akiskal HS, Mallya G,. Criteria for the 'soft' bipolar spectrum: treatment implications. Psychopharmacol. Bull. 1987; 23: 68-73. (Pubitemid 17111666)
33. Mathers CD, Lopez AD, Murray CJL,. The burden of disease and mortality by condition: Data, methods, and results for 2001. In:, Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJL, (eds). Global Burden of Disease and Risk Factors. Oxford University Press and World Bank, New York, 2006; 45-240.
34. Ösby U, Brandt L, Correia N, Ekbom A, Sparén P,. Excess mortality in bipolar and unipolar disorder in Sweden. Arch. Gen. Psychiatry 2001; 58: 844-850. (Pubitemid 32979302)
35. Tondo L, Isacsson G, Baldessarini R,. Suicidal behavior in bipolar disorder: risk and prevention. CNS Drugs 2003; 17: 491-511. (Pubitemid 36693704)
36. Khan A, Leventhal RM, Khan S, Brown WA,. Suicide risk in patients with anxiety disorders: a meta-analysis of the FDA database. J. Affect. Disord. 2002; 68: 183-190. (Pubitemid 34628325)
37. Noyes R Jr,. Suicide and panic disorder: a review. J. Affect. Disord. 1991; 22: 1-11.
38. Isometsä ET, Aro HM, Henriksson MM, Heikkinen ME, Lönnqvist JK,. Suicide in major depression in different treatment settings. J. Clin. Psychiatry 1994; 55: 523-527.
39. Koukopoulos A, Albert MJ, Sani G, Koukopoulos AE, Girardi P,. Mixed depressive states: nosologic and therapeutic issues. Int. Rev. Psychiatry 2005; 17: 21-37. (Pubitemid 40591404)
40. Akiskal HS, Benazzi F, Perugi G, Rihmer Z,. Agitated 'unipolar' depression re-conceptualized as a depressive mixed state: implications for the antidepressant-suicide controversy. J. Affect. Disord. 2005; 85: 245-258. (Pubitemid 40386508)
41. Balázs J, Benazzi F, Rihmer Z, Rihmer A, Akiskal KK, Akiskal HS,. The close link between suicide attempts and mixed (bipolar) depression: implications for suicide prevention. J. Affect. Disord. 2006; 91: 133-138.
42. Koukopoulos A, Faedda G, Proietti R, D'Amico S, de Pisa E, Simonetto C,. Un syndrome dépressif mixte. Encéphale 1992; 18: 19-21.
43. Jameison GR,. Suicide and mental disease: a clinical analysis of one hundred cases. Arch. Neurol. Psychiatry 1936; 36: 1-12.
44. Kotin J, Goodwin FK,. Depression during mania: clinical observation and theoretical implications. Am. J. Psychiatry 1972; 129: 679-686.
45. Rihmer Z, Akiskal H,. Do antidepressants t(h)reat(en) depressives? Toward a clinically judicious formulation of the antidepressant-suicidality FDA advisory in light of declining national suicide statistics from many countries. J. Affect. Disord. 2006; 94: 3-13. (Pubitemid 44093033)
46. Valtonen HM, Suominen K, Haukka J, et al,. Differences in incidence of suicide attempts during phases of bipolar I and II disorders. Bipolar Disord. 2008; 10: 588-596. (Pubitemid 352005790)
47. Pompili M, Innamorati M, Giupponi G, et al,. Prädiktion des Suizidrisikos bei bipolar und unipolar depressiven Patienten. Wechselwirkung von Temperament und Persönlichkeit. Nervenarzt 2009; 80: 315-323.
48. Bocchetta A, Fadda D, Satta G, Del Zompo M, Gessa GL, Cocco P,. Long-term lithium treatment and survival from external causes including suicide. J. Clin. Psychopharmacol. 2007; 27: 544-546. (Pubitemid 47415074)
49. Ohgami H, Terao T, Shiotsuki I, Ishii N, Iwata N,. Lithium levels in drinking water and risk of suicide. Br. J. Psychiatry 2009; 194: 464-465.
50. Terao T, Goto S, Inagaki M, Okamoto Y,. Even very low but sustained lithium intake can prevent suicide in the general population? Med. Hypotheses 2009; 73: 811-812.
51. Pompili M, Rihmer Z, Akiskal HS, et al,. Temperament and personality dimensions in suicidal and nonsuicidal psychiatric inpatients. Psychopathology 2008; 41: 313-321.
52. Rihmer A, Rozsa S, Rihmer Z, Gonda X, Akiskal KK, Akiskal HS,. Affective temperaments, as measured by TEMPS-A, among nonviolent suicide attempters. J. Affect. Disord. 2009; 116: 18-22.
53. Akiskal HS, Placidi GF, Maremmani I, et al,. TEMPS-I: delineating the most discriminant traits of the cyclothymic, depressive, hyperthymic and irritable temperaments in a nonpatient population. J. Affect. Disord. 1998; 51: 7-19. (Pubitemid 29009515)
54. Kochman FJ, Hantouche EG, Ferrari P, Lancrenon S, Bayart D, Akiskal HS,. Cyclothymic temperament as a prospective predictor of bipolarity and suicidality in children and adolescents with major depressive disorder. J. Affect. Disord. 2005; 85: 181-189. (Pubitemid 40386538)
55. Smith EG, Craig TJ, Ganoczy D, Walters HM, Valenstein M,. Treatment of veterans with depression who died by suicide: timing and quality of care at last Veterans Health Administration visit. J. Clin. Psychiatry 2010. doi:10.4088/JCP.09m05608blu.
56. Busch KA, Fawcett J, Jacobs DG,. Clinical correlates of inpatient suicide. J. Clin. Psychiatry. 2003; 64: 14-19. (Pubitemid 36182224)
57. Olgiati P, Serretti A, Colombo C,. Retrospective analysis of psychomotor agitation, hypomanic symptoms, and suicidal ideation in unipolar depression. Depress. Anxiety 2006; 23: 389-397. (Pubitemid 44757145)