Omeprazole, but not pantoprazole, reduces the antiplatelet effect of clopidogrel: A randomized clinical crossover trial in patients after myocardial infarction evaluating the clopidogrel-PPIs drug interaction

European Journal of Gastroenterology and Hepatology

Volumn 23, Issue 5, 2011, Pages 396-404

  Fontes Carvalho, Ricardo ^a,b   Albuquerque, Aníbal ^a   Araújo, Carla ^a   Pimentel Nunes, Pedro ^b,c   Ribeiro, Vasco Gama ^a  

^a Department of Cardiology   (Portugal)

^b University of Porto   (Portugal)

^c PORTUGUESE ONCOLOGY INSTITUTE   (Portugal)

Author keywords

Clopidogrel; drug interactions; proton pump inhibitors

Indexed keywords

ACETYLSALICYLIC ACID; ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CLOPIDOGREL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; OMEPRAZOLE; PANTOPRAZOLE; PURINERGIC P2Y12 RECEPTOR;

ACUTE HEART INFARCTION; ADULT; AGED; ANTICOAGULANT THERAPY; ANTICOAGULATION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG ANTAGONISM; DRUG EFFICACY; DRUG RESPONSE; FEMALE; HUMAN; HUMAN CELL; MALE; PATIENT COMPLIANCE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; THROMBOCYTE AGGREGATION INHIBITION;

2-PYRIDINYLMETHYLSULFINYLBENZIMIDAZOLES; AGED; BLOOD PLATELETS; CROSS-OVER STUDIES; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; OMEPRAZOLE; PLATELET AGGREGATION INHIBITORS; PROTON PUMP INHIBITORS; TICLOPIDINE;

EID: 79955057805     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/MEG.0b013e3283460110     Document Type: Article

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