John F. Fallon, PhD: Fifty years of excellence in limb research and counting

Developmental Dynamics

Volumn 240, Issue 5, 2011, Pages 909-914

  Wellik, Deneen ^a   Sun, Xin ^b   Boekhoff Falk, Grace ^c  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACADEMIC ACHIEVEMENT; APOPTOSIS; CELL DEATH; CHICK; DNA MODIFICATION; ELECTRON MICROSCOPY; EMBRYO DEVELOPMENT; GENE MUTATION; LIMB DEVELOPMENT; NOTE; POSTGRADUATE EDUCATION; PRIORITY JOURNAL; PUBLIC FIGURE; PUBLICATION; SOCIAL STATUS; SYMPOSIUM; TEACHER; UNIVERSITY; WORKSHOP;

BIOMEDICAL RESEARCH; EXTREMITIES; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY;

EID: 79955049249     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.22594     Document Type: Note

References (35)

1. Cameron JA, Fallon JF. 1977. Evidence for polarizing zone in the limb buds of Xenopus laevis. Dev Biol 55: 320-330.
2. Carrington JL, Fallon JF. 1984. The stages of flank ectoderm capable of responding to ridge induction in the chick embryo. J Embryol Exp Morphol 84: 19-34.
3. Carrington JL, Fallon JF. 1986. Experimental manipulation leading to induction of dorsal ectodermal ridges on normal limb buds results in a phenocopy of the Eudiplopodia chick mutant. Dev Biol 116: 130-137.
4. Caruccio NC, Martinez-Lopez A, Harris M, Dvorak L, Bitgood J, Simandl BK, Fallon JF. 1999. Constitutive activation of sonic hedgehog signaling in the chicken mutant talpid(2): Shh-independent outgrowth and polarizing activity. Dev Biol 212: 137-149.
5. Chang DT, Lopez A, von Kessler DP, Chiang C, Simandl BK, Zhao R, Seldin MF, Fallon JF, Beachy PA. 1994. Products, genetic linkage and limb patterning activity of a murine hedgehog gene. Development 120: 3339-3353.
6. Chiang C, Litingtung Y, Harris MP, Simandl BK, Li Y, Beachy PA, Fallon JF. 2001. Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function. Dev Biol 236: 421-435.
7. Coelho CN, Krabbenhoft KM, Upholt WB, Fallon JF, Kosher RA. 1991. Altered expression of the chicken homeobox-containing genes GHox-7 and GHox-8 in the limb buds of limbless mutant chick embryos. Development 113: 1487-1493.
8. Crosby GM, Fallon JF. 1975. Inhibitory effect on limb morphogenesis by cells of the polarizing zone coaggregated with pre- or postaxial wing bud mesoderm. Dev Biol 46: 28-39.
9. Dvorak L, Fallon JF. 1987. The ability of the chick wing bud to regulate positional disparity along the anterior-posterior axis. Dev Biol 120: 392-398.
10. Dvorak L, Fallon JF. 1992. The talpid2 chick limb has weak polarizing activity and can respond to retinoic acid and polarizing zone signal. Dev Dyn 193: 40-48.
11. Fallon JF, Crosby GM. 1975a. The relationship of the zone polarizing activity to supernumerary limb formation (twinning) in the chick wing bud. Dev Biol 43: 24-34.
12. Fallon JF, Crosby GM. 1975b. Normal development of the chick wing following removal of the polarizing zone. J Exp Zool 193: 449-455.
13. Fallon JF, Saunders JW Jr. 1968. In vitro analysis of the control of cell death in a zone of prospective necrosis from the chick wing bud. Dev Biol 18: 553-570.
14. Fallon JF, Lopez A, Ros MA, Savage MP, Olwin BB, Simandl BK. 1994. FGF-2: apical ectodermal ridge growth signal for chick limb development. Science 264: 104-107.
15. Harris MP, Hasso SM, Ferguson MW, Fallon JF. 2006. The development of archosaurian first-generation teeth in a chicken mutant. Curr Biol 16: 371-377.
16. Krabbenhoft KM, Fallon JF. 1992. Talpid2 limb bud mesoderm does not express GHox-8 and has an altered expression pattern of GHox-7. Dev Dyn 194: 52-62.
17. Litingtung Y, Dahn RD, Li Y, Fallon JF, Chiang C. 2002. Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity. Nature 418: 979-983.
18. Lopez-Martinez A, Chang DT, Chiang C, Porter JA, Ros MA, Simandl BK, Beachy PA, Fallon JF. 1995. Limb-patterning activity and restricted posterior localization of the amino-terminal product of Sonic hedgehog cleavage. Curr Biol 5: 791-796.
19. Maas SA, Fallon JF. 2004. Isolation of the chicken Lmbr1 coding sequence and characterization of its role during chick limb development. Dev Dyn 229: 520-528.
20. Maas SA, Fallon JF. 2005. Single base pair change in the long-range Sonic hedgehog limb-specific enhancer is a genetic basis for preaxial polydactyly. Dev Dyn 232: 345-348.
21. Pagan SM, Ros MA, Tabin C, Fallon JF. 1996. Surgical removal of limb bud Sonic hedgehog results in posterior skeletal defects. Dev Biol 180: 35-40.
22. Riley BB, Savage MP, Simandl BK, Olwin BB, Fallon JF. 1993. Retroviral expression of FGF-2 (bFGF) affects patterning in chick limb bud. Development 118: 95-104.
23. Ros MA, Lyons G, Kosher RA, Upholt WB, Coelho CN, Fallon JF. 1992. Apical ridge dependent and independent mesodermal domains of GHox-7 and GHox-8 expression in chick limb buds. Development 116: 811-818.
24. Ros MA, Lyons G, Fallon JF. 1993. Spatial and temporal analysis of homeobox genes expressed in chick limb buds by whole-mount in situ hybridization. Prog Clin Biol Res 383A: 79-87.
25. Ros MA, Lopez-Martinez A, Simandl BK, Rodriguez C, Izpisua Belmonte JC, Dahn R, Fallon JF. 1996. The limb field mesoderm determines initial limb bud anteroposterior asymmetry and budding independent of sonic hedgehog or apical ectodermal gene expressions. Development 122: 2319-2330.
26. Ros MA, Dahn RD, Fernandez-Teran M, Rashka K, Caruccio NC, Hasso SM, Bitgood JJ, Lancman JJ, Fallon JF. 2003. The chick oligozeugodactyly (ozd) mutant lacks sonic hedgehog function in the limb. Development 130: 527-537.
27. Rowe DA, Fallon JF. 1981. The effect of removing posterior apical ectodermal ridge of the chick wing and leg on pattern formation. J Embryol Exp Morphol 65(suppl): 309-325.
28. Rowe DA, Fallon JF. 1982a. Normal anterior pattern formation after barrier placement in the chick leg: further evidence on the action of polarizing zone. J Embryol Exp Morphol 69: 1-6.
29. Rowe DA, Fallon JF. 1982b. The proximodistal determination of skeletal parts in the developing chick leg. J Embryol Exp Morphol 68: 1-7.
30. Rowe DA, Cairns JM, Fallon JF. 1982. Spatial and temporal patterns of cell death in limb bud mesoderm after apical ectodermal ridge removal. Dev Biol 93: 83-91.
31. Savage MP, Hart CE, Riley BB, Sasse J, Olwin BB, Fallon JF. 1993. Distribution of FGF-2 suggests it has a role in chick limb bud growth. Dev Dyn 198: 159-170.
32. Suzuki T, Hasso SM, Fallon JF. 2008. Unique SMAD1/5/8 activity at the phalanx-forming region determines digit identity. Proc Natl Acad Sci U S A 105: 4185-4190.
33. Todt WL, Fallon JF. 1984. Development of the apical ectodermal ridge in the chick wing bud. J Embryol Exp Morphol 80: 21-41.
34. Todt WL, Fallon JF. 1987. Posterior apical ectodermal ridge removal in the chick wing bud triggers a series of events resulting in defective anterior pattern formation. Development 101: 501-515.
35. Wang B, Fallon JF, Beachy PA. 2000. Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb. Cell 100: 423-434.