Expression of key retinoic acid modulating genes suggests active regulation during development and regeneration of the amphibian limb

Developmental Dynamics

Volumn 240, Issue 5, 2011, Pages 1259-1270

  Mcewan, James ^a   Lynch, Joshua ^a   Beck, Caroline W ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Limb; Morphogen; Patterning; Positional information; Regeneration; Retinoic acid

Indexed keywords

CELLULAR RETINOIC ACID BINDING PROTEIN 2; CYTOCHROME P450 26A1; CYTOCHROME P450 26B; MORPHOGEN; RETINOIC ACID; RETINOLDEHYDE HYDROXYGENASE 2; RETINOLDEHYDE HYDROXYGENASE 3; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLASTEMA; CONTROLLED STUDY; EMBRYO; FORELIMB; GENE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HINDLIMB; LIMB DEVELOPMENT; LIMB REGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; TADPOLE; UPREGULATION; XENOPUS;

AMPHIBIANS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; EXTREMITIES; IN SITU HYBRIDIZATION; REGENERATION; TRETINOIN;

AMPHIBIA;

EID: 79955031869     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.22555     Document Type: Article

References (59)

1. Abu-Abed S, Dolle P, Metzger D, Beckett B, Chambon P, Petkovich M. 2001. The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures. Genes Dev 15: 226-240.
2. Astrom A, Pettersson U, Chambon P, Voorhees JJ. 1994. Retinoic acid induction of human cellular retinoic acid-binding protein-II gene transcription is mediated by retinoic acid receptor-retinoid X receptor heterodimers bound to one far upstream retinoic acid-responsive element with 5-base pair spacing. J Biol Chem 269: 22334-22339.
3. Azciotia V, Aracil M, Martinez AC, Torres, M. 2005. The homeodomain protein Meis1 is essential for definative hematopoiesis and vascular patterning in the mouse embryo. Dev Biol 280: 307-320
4. Barker DM, Beck CW. 2009. Overexpression of the transcription factor Msx1 is insufficient to drive complete regeneration of refractory stage Xenopus laevis hindlimbs. Dev Dyn 238: 1366-1378.
5. Beck CW, Slack JM. 1998. Analysis of the developing Xenopus tail bud reveals separate phases of gene expression during determination and outgrowth. Mech Dev 72: 41-52.
6. Beck CW, Christen B, Slack JM. 2003. Molecular pathways needed for regeneration of spinal cord and muscle in a vertebrate. Dev Cell 5: 429-439.
7. Beck CW, Izpisua Belmonte JC, Christen B. 2009. Beyond early development: Xenopus as an emerging model for the study of regenerative mechanisms. Dev Dyn 238: 1226-1248.
8. Blomhoff R, Blomhoff HK. 2006. Overview of retinoid metabolism and function. J Neurobiol 66: 606-630.
9. Boylan JF, Gudas LJ. 1992. The level of CRABP-I expression influences the amounts and types of all-trans-retinoic acid metabolites in F9 teratocarcinoma stem cells. J Biol Chem 267: 21486- 21491.
10. Budhu AS, Noy N. 2002. Direct channeling of retinoic acid between cellular retinoic acid-binding protein II and retinoic acid receptor sensitizes mammary carcinoma cells to retinoic acid-induced growth arrest. Mol Cell Biol 22: 2632-2641.
11. Cameron JA, Fallon JF. 1977. The absence of cell death during development of free digits in amphibians. Dev Biol 55: 331-338.
12. Capdevila J, Tsukui T, Rodriquez Esteban C, Zappavigna V, Izpisua Belmonte JC. 1999. Control of vertebrate limb outgrowth by the proximal factor Meis2 and distal antagonism of BMPs by Gremlin. Mol Cell 4: 839-849.
13. Christen B, Slack JMW. 1998. All limbs are not the same. Nature 395: 230-231.
14. Dent JN. 1962. Limb regeneration in larvae and metamorphosing individuals of the South African clawed toad. J Morphol 110: 61-78.
15. Duester G. 2007. Retinoic acid regulation of the somitogenesis clock. Birth Defects Res C Embryo Today 81: 84-92.
16. Fawcett D, Pasceri P, Fraser R, Colbert M, Rossant J, Giguere V. 1995. Postaxial polydactyly in forelimbs of CRABP-II mutant mice. Development 121: 671-679.
17. Gibert Y, Gajewski A, Meyer A, Begemann G. 2006. Induction and prepatterning of the zebrafish pectoral fin bud requires axial retinoic acid signaling. Development 133: 2649-2659.
18. Gorry P, Lufkin T, Dierich A, Rochette-Egly C, Decimo D, Dolle P, Mark M, Durand B, Chambon P. 1994. The cellular retinoic acid binding protein I is dispensable. Proc Natl Acad Sci USA 91: 9032-9036.
19. Grandel H, Lun K, Rauch GJ, Rhinn M, Piotrowski T, Houart C, Sordino P, Kuchler AM, Schulte-Merker S, Geisler R, Holder N, Wilson SW, Brand M. 2002. Retinoic acid signalling in the zebrafish embryo is necessary during pre-segmentation stages to pattern the anterior-posterior axis of the CNS and to induce a pectoral fin bud. Development 129: 2851-2865.
20. Guthrie S. 1996. Patterning the hindbrain. Curr Opin Neurobiol 6: 41-48.
21. Hisa T, Spence SE, Rachel RA, Fujita M, Nakamura T, Ward JM, Devor-Henneman DE, Saiki Y, Haruo K, Tessarollo L, Jenkins NA, Copeland NG. 2004. Hematopoietic, angiogenic and eye defects in Meis1 mutant animals. EMBO J. 23: 450-459.
22. Hoffman LM, Garcha K, Karamboulas K, Cowan MF, Drysdale LM, Horton WA, Underhill TM. 2006. BMP action in skeletogenesis involves attenuation of retinoid signaling. J Cell Biol 174: 101-113.
23. Kroll KL, Amaya E. 1996. Transgenic Xenopus embryos from sperm nuclear transplantations reveal FGF signaling requirements during gastrulation. Development 122: 3173-3183.
24. Lampron C, Rochette-Egly C, Gorry P, Dolle P, Mark M, Lufkin T, LeMeur M, Chambon P. 1995. Mice deficient in cellular retinoic acid binding protein II (CRABPII) or in both CRABPI and CRABPII are essentially normal. Development 121: 539-548.
25. Laue K, Janicke M, Plaster N, Sonntag C, Hammerschmidt M. 2008. Restriction of retinoic acid activity by Cyp26b1 is required for proper timing and patterning of osteogenesis during zebrafish development. Development 135: 3775-3787.
26. Lee GS, Kochhar DM, Collins MD. 2004. Retinoid-induced limb malformations. Curr Pharm Des 10: 2657-2699.
27. Loudig O, Babichuk C, White J, Abu-Abed S, Mueller C, Petkovich M. 2000. Cytochrome P450RAI(CYP26) promoter: a distinct composite retinoic acid response element underlies the complex regulation of retinoic acid metabolism. Mol Endocrinol 14: 1483-1497.
28. Lynch J, McEwan J, Beck CW. 2010. Analysis of the expression of retinoic acid metabolising genes during Xenopus laevis organogenesis. Gene Exp Pattern (in press).
29. Maddin HC, Eckhart L, Jaeger K, Russell AP, Ghannadan M. 2009. The anatomy and development of the claws of Xenopus laevis (Lissamphibia: Anura) reveal alternate pathways of structural evolution in the integument of tetrapods. J Anat 214: 607-619.
30. Maden M. 1982. Vitamin A and pattern formation in the regenerating limb. Nature 295: 672-675.
31. Maden M. 1998. Retinoids as endogenous components of the regenerating limb and tail. Wound Repair Regen 6: 358-365.
32. Maden M, Ong DE, Summerbell D, Chytil F. 1989. The role of retinoid-binding proteins in the generation of pattern in the developing limb, the regenerating limb and the nervous system. Development 107(Supp): 109-119.
33. Martin P. Tissue patterning in the developing mouse limb. 1990. Int J Dev Biol 34: 323-336
34. Mercader N, Leonardo E, Azpiazu N, Serrano A, Morata G, Martinez C, Torres M. 1999. Conserved regulation of proximodistal limb axis development by Meis1/Hth. Nature 402: 425-429.
35. Mercader N, Leonardo E, Piedra ME, Martinez AC, Ros MA, Torres M. 2000. Opposing RA and FGF signals control proximodistal vertebrate limb development through regulation of Meis genes. Development 127: 3961-3970.
36. Mercader N, Tanaka EM, Torres M. 2005. Proximodistal identity during vertebrate limb regeneration is regulated by Meis homeodomain proteins. Development 132: 4131-4142.
37. Merino R, Ganan Y, Macias D, Rodriguez-Leon J, Hurle JM. 1999. Bone morphogenetic proteins regulate interdigital cell death in the avian embryo. Ann NY Acad Sci 887: 120-132.
38. Niazi IA, Saxena S. 1978. Abnormal hind limb regeneration in tadpoles of the toad, Bufo andersoni, exposed to excess vitamin A. Folia Biol (Krakow) 26: 3-8.
39. Niederreither K, Dolle P. 2008. Retinoic acid in development: towards an integrated view. Nat Rev Genet 9: 541-553.
40. Niederreither K, McCaffery P, Drager UC, Chambon P, Dolle P. 1997. Restricted expression and retinoic acid-induced downregulation of the retinaldehyde dehydrogenase type 2 (RALDH-2) gene during mouse development. Mech Dev 62: 67-78.
41. Niederreither K, Vermot J, Schuhbaur B, Chambon P, Dolle P. 2002. Embryonic retinoic acid synthesis is required for forelimb growth and anteroposterior patterning in the mouse. Development 129: 3563-3574.
42. Nieuwkoop PD, Faber J. 1967. A Normal Table of Xenopus laevis (Daudin). Elsevier/North Holland, Amsterdam.
43. Noji S, Nohno T, Koyama E, Muto K, Ohyama K, Aoki Y, Tamura K, Ohsugi K, Ide H, Taniguchi S, Saito T. 1991. Retinoic acid induces polarizing activity but is unlikely to be a morphogen in the chick limb bud. Nature 350: 83-86.
44. Pearl EJ, Barker D, Day RC, Beck CW. 2008. Identification of genes associated with regenerative success of Xenopus laevis hindlimbs. BMC Dev Biol 8: 66.
45. Reijntjes S, Blentic A, Gale E, Maden M. 2005. The control of morphogen signalling: regulation of the synthesis and catabolism of retinoic acid in the developing embryo. Dev Biol 285: 224- 237.
46. Ruberte E, Friederich V, Morriss-Kay G, Chambon P. 1992. Differential distribution patterns of CRABP I and CRABP II transcripts during mouse embryogenesis. Development 115: 973-987.
47. Sakai Y, Meno C, Fujii H, Nishino J, Shiratori H, Saijoh Y, Rossant J, Hamada H. 2001. The retinoic acid-inactivating enzyme CYP26 is essential for establishing an uneven distribution of retinoic acid along the anterio-posterior axis within the mouse embryo. Genes Dev 15: 213-225.
48. Scadding SR, Maden M. 1986a. Comparison of the effects of vitamin A on limb development and regeneration in the axolotl, Ambystoma mexicanum. J Embryol Exp Morphol 91: 19-34.
49. Scadding SR, Maden M. 1986b. Comparison of the effects of vitamin A on limb development and regeneration in Xenopus laevis tadpoles. J Embryol Exp Morphol 91: 35-53.
50. Scadding SR, Maden M. 1986c. The effects of local application of retinoic acid on limb development and regeneration in tadpoles of Xenopus laevis. J Embryol Exp Morphol 91: 55-63.
51. Spoorendonk KM, Peterson-Maduro J, Renn J, Trowe T, Kranenbarg S, Winkler C, Schulte-Merker S. 2008. Retinoic acid and Cyp26b1 are critical regulators of osteogenesis in the axial skeleton. Development 135: 3765- 3774.
52. Straube WL, Tanaka EM. 2006. Reversibility of the differentiated state: regeneration in amphibians. Artif Organs 30: 743-755.
53. Summerbell D. 1983. The effect of local application of retinoic acid to the anterior margin of the developing chick limb. J Embryol Exp Morphol 78: 269-289.
54. Swindell EC, Thaller C, Sockanathan S, Petkovich M, Jessell TM, Eichele G. 1999. Complementary domains of retinoic acid production and degradation in the early chick embryo. Dev Biol 216: 282-296.
55. Thaller C, Eichele G. 1987. Identification and spatial distribution of retinoids in the developing chick limb bud. Nature 327: 625-628.
56. Tickle C, Alberts B, Wolpert L, Lee J. 1982. Local application of retinoic acid to the limb bond mimics the action of the polarizing region. Nature 296: 564-566.
57. Wanek N, Gardiner DM, Muneoka K, Bryant SV. 1991. Conversion by retinoic acid of anterior cells into ZPA cells in the chick wing bud. Nature 350: 81-83.
58. Yashiro K, Zhao X, Uehara M, Yamashita K, Nishijima M, Nishino J, Saijoh Y, Sakai Y, Hamada H. 2004. Regulation of retinoic acid distribution is required for proximodistal patterning and outgrowth of the developing mouse limb. Dev Cell 6: 411-422.
59. Zhao X, Sirbu IO, Mic FA, Molotkova N, Molotkov A, Kumar S, Duester G. 2009. Retinoic acid promotes limb induction through effects on body axis extension but is unnecessary for limb patterning. Curr Biol 19: 1050-1057.