Association of subclinical hypothyroidism and phenotype, insulin resistance, and lipid parameters in young women with polycystic ovary syndrome

Fertility and Sterility

Volumn 95, Issue 6, 2011, Pages 2039-2043

  Ganie, Mohd Ashraf ^a   Laway, Bashir Ahmad ^a   Wani, Tariq Ahmed ^a   Zargar, Mohd Afzal ^b   Nisar, Sobia ^c   Ahamed, Feroze ^a   Khurana, M L ^d   Ahmed, Sanjeed ^a  

^a SHER I KASHMIR INSTITUTE OF MEDICAL SCIENCES   (India)

^b UNIVERSITY OF KASHMIR   (India)

^c GOVERNMENT MEDICAL COLLEGE   (India)

^d ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

insulin resistance; Polycystic ovary syndrome; serum lipids; subclinical hypothyroidism

Indexed keywords

GLUCOSE; INSULIN; THYROTROPIN; TRIACYLGLYCEROL;

ADULT; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; DISEASE DURATION; FEMALE; FREE LIOTHYRONINE INDEX; FREE THYROXINE INDEX; GLUCOSE BLOOD LEVEL; HIRSUTISM; HUMAN; HYPOTHYROIDISM; INSULIN RESISTANCE; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MENSTRUATION DISORDER; ORAL GLUCOSE TOLERANCE TEST; OVARY POLYCYSTIC DISEASE; PHENOTYPE; PRIORITY JOURNAL; SUBCLINICAL HYPOTHYROIDISM; TRIACYLGLYCEROL BLOOD LEVEL;

ADOLESCENT; ADULT; ASYMPTOMATIC DISEASES; CASE-CONTROL STUDIES; COHORT STUDIES; FEMALE; HUMANS; HYPOTHYROIDISM; INSULIN RESISTANCE; LIPID METABOLISM; LIPIDS; PHENOTYPE; POLYCYSTIC OVARY SYNDROME; THYROID HORMONES; THYROTROPIN; YOUNG ADULT;

EID: 79955031184     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2011.01.149     Document Type: Article

References (31)

1. I.F. Stein, and M.L. Leventhal Amenorrhoea associated with bilateral polycystic ovaries Am J Obstet Gynecol 29 1935 181 191
2. S. Franks Polycystic ovary syndrome N Engl J Med 333 1995 853 861
3. R. Homberg Polycystic ovary syndrome: from gynaecological curiosity to multisystem endocrinopathy Hum Reprod 11 1996 29 39
4. A. Dunaif Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis Endocr Rev 18 1997 774 800 (Pubitemid 28009567)
5. M.O. Goodarzi, and S.G. Korenman The importance of insulin resistance in polycystic ovary syndrome Fertil Steril 80 2003 255 258 (Pubitemid 36959775)
6. B. Kulshreshtha, M.A. Ganie, E.P. Praveen, N. Gupta, M.L. Khurana, and A. Seith Insulin response to oral glucose in healthy, lean young women and patients with polycystic ovary syndrome Gynecol Endocrinol 24 2008 637 643
7. A.E. Nieuwenhuis-Ruifrok, W.K. Kuchenbecker, A. Hoek, P. Middleton, and R.J. Norman Insulin sensitizing drugs for weight loss in women of reproductive age who are overweight or obese: systematic review and meta-analysis Hum Reprod Update 15 2009 57 68
8. M.A. Ganie, M.L. Khurana, M. Eunice, N. Gupta, M. Gulati, and S.N. Dwivedi Comparison of efficacy of spironolactone with metformin in the management of polycystic ovary syndrome: an open-labeled study J Clin Endocrinol Metab 89 2004 2756 2762 (Pubitemid 38766362)
9. C. Rochon, I. Tauveron, C. Dejax, P. Benoit, P. Capitan, and A. Fabricio Response of glucose disposal to hyperinsulinemia in human hypothyroidism and hyperthyroidism Clin Sci (Lond) 104 2003 7 15 (Pubitemid 36249918)
10. T. Seppel, A. Kosel, and R. Schlaghecke Bioelectrical impedance assessment of body composition in thyroid disease Eur J Endocrinol 136 1997 493 498 (Pubitemid 27239610)
11. S.M. Wajner, M.S. Wagner, and A.L. Maia Clinical implications of altered thyroid status in male testicular function Arq Bras Endocrinol Metabol 53 2009 976 982
12. W. Raber, P. Nowotny, E. Vytiska-Binstorfer, and H. Vierhapper Thyroxine treatment modified in infertile women according to thyroxine-releasing hormone testing: 5 year follow-up of 283 women referred after exclusion of absolute causes of infertility Hum Reprod 18 2003 707 714 (Pubitemid 36426946)
13. N.S. Setian Hypothyroidism in children: diagnosis and treatment J Pediatr (Rio J) 83 2007 S209 S216
14. J.K. Zawadski, and A. Dunaif Diagnostic criteria for polycystic ovary syndrome: towards a rational approach A. Dunaif, J.R. Givens, F.P. Haseltine, G.R. Merriam, Polycystic ovary syndrome 1992 Blackwell Scientific Boston 377 384
15. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS) Hum Reprod 19 2004 41 47
16. R. Azziz, E. Carmina, D. Dewailly, E. Diamanti-Kandarakis, H.F. Escobar-Morreale, and W. Futterweit Androgen Excess Society. Positions statement: criteria for defining polycystic ovary syndrome as a predominantly hyperandrogenic syndrome: an Androgen Excess Society guideline J Clin Endocrinol Metab 91 2006 4237 4242
17. S. Ghosh, S.N. Kabir, A. Pakrashi, S. Chatterjee, and B. Chakravarty Subclinical hypothyroidism: a determinant of polycystic ovary syndrome Horm Res 39 1993 61 66 (Pubitemid 23243141)
18. M.A. Ganie, R.K. Marwaha, R. Aggarwal, and S. Singh High prevalence of polycystic ovary syndrome characteristics in girls with euthyroid chronic lymphocytic thyroiditis: a case-control study Eur J Endocrinol 162 2010 1117 1122
19. A. Mueller, C. Schöfl, R. Dittrich, S. Cupisti, P.G. Oppelt, and R.L. Schild Thyroid-stimulating hormone is associated with insulin resistance independently of body mass index and age in women with polycystic ovary syndrome Hum Reprod 24 2009 2924 2930
20. D. Ferriman, and J.D. Gallwey Clinical assessment of body hair growth in women J Clin Endocrinol Metab 21 1961 1440 1447
21. A.H. Balen, J.S. Laven, S.L. Tan, and D. Dewailly Ultrasound assessment of the polycystic ovary: international consensus definitions Hum Reprod Update 9 2003 505 514 (Pubitemid 38072143)
22. M. Cakir, R. Sari, O. Tosun, O. Saka, and U. Karayalcin Reproducibility of fasting and OGTT-derived insulin resistance indices in normoglycemic women Can J Diabetes 30 2006 46 51 (Pubitemid 44411672)
23. Z. Radikova, J. Koska, M. Huckova, L. Ksinantova, R. Imrich, and M. Vigas Insulin sensitivity indices: a proposal of cut-off points for simple identification of insulin-resistant subjects Exp Clin Endocrinol Diabetes 114 2006 249 256 (Pubitemid 44065178)
24. B.A. Lamberg Glucose metabolism in thyroid disease Acta Med Scand 178 1965 351 362
25. A. Roos, S.J.L. Bakker, T.P. Links, R.O.B. Gans, and B.H.R. Wolffenbuttel Thyroid function is associated with components of the metabolic syndrome in euthyroid subjects J Clin Endocrinol Metab 92 2007 491 496
26. I.M.D. Jackson, C.R.M. Prentice, and M.T. McKiddie The effect of hypothyroidism on glucose tolerance and insulin metabolism J Endocrinol 47 1970 257 258
27. E. Maratou, D.J. Hadjidakis, A. Kollias, K. Tsegka, M. Peppa, and M. Alevizaki Studies of insulin resistance in patients with clinical and subclinical hypothyroidism Eur J Endocrinol 160 2009 785 790
28. A. Tuzcu, M. Bahceci, D. Gokalp, Y. Tuzun, and K. Gunes Subclinical hypothyroidism may be associated with elevated high-sensitive C-reactive protein (low grade inflammation) and fasting hyperinsulinemia Endocrine J 52 2005 89 94 (Pubitemid 40410323)
29. A. Al Sayed, N. Al Ali, Y. Bo Abbas, and E. Alfadhli Subclinical hypothyroidism is associated with early insulin resistance in Kuwaiti women Endocr J 53 2006 653 657 (Pubitemid 44691018)
30. G. Brenta, G. Berg, P. Arias, V. Zago, M. Schnitman, and M.L. Muzzio Lipoprotein alterations, hepatic lipase activity, and insulin sensitivity in subclinical hypothyroidism: response to L-T4 treatment Thyroid 17 2007 453 460 (Pubitemid 46878848)
31. R. Dittrich, N. Kajaia, S. Cupisti, I. Hoffmann, M.W. Beckmann, and A. Mueller Association of thyroid-stimulating hormone with insulin resistance and androgen parameters in women with PCOS Reprod Biomed Online 19 2009 319 325