MYC, TP53, and chromosome 17 copy-number alterations in multiple gastric cancer cell lines and in their parental primary tumors

Journal of Biomedicine and Biotechnology

Volumn 2011, Issue , 2011, Pages

  Leal, Mariana Ferreira ^a   Calcagno, Danielle Queiroz ^b   Borges Da Costa, Joana De Fátima Ferreira ^b   Silva, Tanielly Cristina Raiol ^b   Khayat, André Salim ^b   Chen, Elizabeth Suchi ^a   Assumpo, Paulo Pimentel ^b   De Arruda Cardoso Smith, Marília ^a   Burbano, Rommel Rodríguez ^b  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF PARÁ   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

MYC PROTEIN; PROTEIN P53;

ARTICLE; CANCER CELL CULTURE; CHROMOSOME 17; FLUORESCENCE IN SITU HYBRIDIZATION; GENE LOSS; HUMAN; HUMAN CELL; MUTATION; ONCOGENE MYC; PRIMARY TUMOR; STOMACH CANCER; TRISOMY; TUMOR SUPPRESSOR GENE; CHROMOSOME ABERRATION; COMPARATIVE STUDY; GENE DOSAGE; GENETICS; STOMACH TUMOR; TUMOR CELL LINE;

CELL LINE, TUMOR; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 17; GENE DOSAGE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; PROTO-ONCOGENE PROTEINS C-MYC; STOMACH NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 79955029834     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2011/631268     Document Type: Article

References (31)

1. Ottini L., Falchetti M., Lupi R., Rizzolo P., Agnese V., Colucci G., Bazan V., Russo A., Patterns of genomic instability in gastric cancer: clinical implications and perspectives Annals of Oncology 2006 17 7 vii97 vii102
2. Parkin D. M., Bray F., Ferlay J., Pisani P., Global cancer statistics, 2002 Ca-A Cancer Journal for Clinicians 2005 55 2 74 108 (Pubitemid 40372904)
3. Ferti-Passantonopoulou A. D., Panani A. D., Vlachos J. D., Raptis S. A., Common cytogenetic findings in gastric cancer Cancer Genetics and Cytogenetics 1987 24 1 63 73 (Pubitemid 17206451)
4. Xia J. C., Lu S., Geng J. S., Fu S. B., Li P., Liu Q. Z., Direct chromosome analysis of ten primary gastric cancers Cancer Genetics and Cytogenetics 1998 102 1 88 90 (Pubitemid 128712618)
5. Ochi H., Douglass H. O., Sandberg A. A., Cytogenetic studies in primary gastric cancer Cancer Genetics and Cytogenetics 1986 22 4 295 307 (Pubitemid 16012070)
6. Kitayama Y., Igarashi H., Sugimura H., Different vulnerability among chromosomes to numerical instability in gastric carcinogenesis: stage-dependent analysis by FISH with the use of microwave irradiation Clinical Cancer Research 2000 6 8 3139 3146 (Pubitemid 30637739)
7. Assumpcao P. P., Ishak G., Chen E. S., Numerical aberrations of chromosome 8 detected by conventional cytogenetics and fluorescence in situ hybridization in individuals from northern Brazil with gastric adenocarcinoma Cancer Genetics and Cytogenetics 2006 169 1 45 49 (Pubitemid 44093735)
8. Greshock J., Nathanson K., Martin A. M., Zhang L., Coukos G., Weber B. L., Zaks T. Z., Cancer cell lines as genetic models of their parent histology: analyses based on array comparative genomic hybridization Cancer Research 2007 67 8 3594 3600 (Pubitemid 46762143)
9. Jin Y., Zhang H., Tsao S. W., Cytogenetic and molecular genetic characterization of immortalized human ovarian surface epithelial cell lines: consistent loss of chromosome 13 and amplification of chromosome 20 Gynecologic Oncology 2004 92 1 183 191 (Pubitemid 38147389)
10. Ratsch S. B., Gao Q., Srinivasan S., Wazer D. E., Band V., Multiple genetic changes are required for efficient immortalization of different subtypes of normal human mammary epithelial cells Radiation Research 2001 155 1, part 2 143 150 (Pubitemid 33723530)
11. Meisner L. F., Wu S. Q., Christian B. J., Reznikoff C. A., Cytogenetic instability with balanced chromosome changes in an SV40 transformed human uroepithelial cell line Cancer Research 1988 48 11 3215 3220
12. Leal M. F., Martins do Nascimento J. L., da Silva C. E. A., Establishment and conventional cytogenetic characterization of three gastric cancer cell lines Cancer Genetics and Cytogenetics 2009 195 1 85 91
13. Costa Guimaraes A., Goncalves Quintana L., Ferreira Leal M., Aneuploidy of chromosome 8 detected by fluorescence in situ hybridisation in ACP01 cell line gastric adenocarcinoma Clinical and Experimental Medicine 2006 6 3 129 133 (Pubitemid 44630744)
14. Stamouli M. I., Ferti A. D., Panani A. D., Raftakis J., Consoli C., Raptis S. A., Young B. D., Application of multiplex fluorescence in situ hybridization in the cytogenetic analysis of primary gastric carcinoma Cancer Genetics and Cytogenetics 2002 135 1 23 27 (Pubitemid 34601172)
15. Hopman A. H. N., Ramaekers F. C. S., Raap A. K., Beck J. L. M., Devilee P., Van Der Ploeg M., Vooijs G. P., In situ hybridization as a tool to study numerical chromosome aberrations in solid bladder tumors Histochemistry 1988 89 4 307 316
16. Kallioniemi A., Visakorpi T., Karhu R., Pinkel D., Kallioniemi O. P., Gene copy number analysis by fluorescence in situ hybridization and comparative genomic hybridization Methods 1996 9 1 113 121 (Pubitemid 26125916)
17. Lima E. M., Rissino J. D., Harada M. L., Conventional cytogenetic characterization of a new cell line, ACP01, established from a primary human gastric tumor Brazilian Journal of Medical and Biological Research 2004 37 12 1831 1838 (Pubitemid 40100413)
18. Guimaraes A. C., Lima E. M., Khayat A. S., Interrelationships among chromosome aneuploidy, promoter hypermethylation, and protein expression of the CDKN2A gene in individuals from northern Brazil with gastric adenocarcinoma Cancer Genetics and Cytogenetics 2007 179 1 45 51 (Pubitemid 350019615)
19. Calcagno D. Q., Leal M. F., Seabra A. D., Interrelationship between chromosome 8 aneuploidy, C-MYC amplification and increased expression in individuals from northern Brazil with gastric adenocarcinoma World Journal of Gastroenterology 2006 12 38 6207 6211 (Pubitemid 44688174)
20. Queiroz Calcagno D., Ferreira Leal M., Satomi Takeno S., Aneuploidy of chromosome 8 and C-MYC amplification in individuals from northern Brazil with gastric adenocarcinoma Anticancer Research 2005 25 6 B 4069 4074 (Pubitemid 41665187)
21. Panani A. D., Cytogenetic and molecular aspects of gastric cancer: clinical implications Cancer Letters 2008 266 2 99 115
22. Burbano R., Assumpcao P. P., Ferreira Leal M., C-MYC locus amplification as metastasis predictor in intestinal-type gastric adenocarcinomas: CGH study in Brazil Anticancer Research 2006 26 4 B 2909 2914 (Pubitemid 44164249)
23. Calcagno D. Q., Guimaraes A. C., Leal M. F., MYC insertions in diffuse-type gastric adenocarcinoma Anticancer Research 2009 29 7 2479 2483
24. Koo S. H., Kwon K. C., Shin S. Y., Jeon Y. M., Park J. W., Kim S. H., Noh S. M., Genetic alterations of gastric cancer: comparative genomic hybridization and fluorescence in situ hybridization studies Cancer Genetics and Cytogenetics 2000 117 2 97 103 (Pubitemid 30125806)
25. Hara T., Ooi A., Kobayashi M., Mai M., Yanagihara K., Nakanishi I., Amplification of c-myc, K-sam, and c-met in gastric cancers: detection by fluorescence in situ hybridization Laboratory Investigation 1998 78 9 1143 1153 (Pubitemid 28440830)
26. Calcagno D. Q., Leal M. F., Assumpcao P. P., Smith M. D. A. C., Burbano R. R., MYC and gastric adenocarcinoma carcinogenesis World Journal of Gastroenterology 2008 14 39 5962 5968
27. Khayat A. S., Guimaraes A. C., Calcagno D. Q., Interrelationship between TP53 gene deletion, protein expression and chromosome 17 aneusomy in gastric adenocarcinoma BMC Gastroenterology 2009 9, article 55
28. Satomi Takeno S., Leal M. F., Frias Lisboa L. C., Genomic alterations in diffuse-type gastric cancer as shown by high-resolution comparative genomic hybridization Cancer Genetics and Cytogenetics 2009 190 1 1 7
29. Szymanska K., Hainaut P., TP53 and mutations in human cancer Acta Biochimica Polonica 2003 50 1 231 238 (Pubitemid 37034245)
30. Reddel R. R., The role of senescence and immortalization in carcinogenesis Carcinogenesis 2000 21 3 477 484 (Pubitemid 30137933)
31. Rubin H., Promise and problems in relating cellular senescence in vitro to aging in vivo Archives of Gerontology and Geriatrics 2002 34 3 275 286 (Pubitemid 34224167)