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Volumn 69, Issue 3, 2011, Pages 151-157

Treatment of severe drooling with botulinum toxin in amyotrophic lateral sclerosis and Parkinson's disease: Efficacy and possible mechanisms

Author keywords

Botulinum toxin type A; neurodegenerative disease; saliva; salivary gland; sialorrhoea

Indexed keywords

ACETYLCHOLINE; BOTULINUM TOXIN A; MUSCLE RELAXANT AGENT; ONABOTULINUMTOXINA;

EID: 79955025790     PISSN: 00016357     EISSN: 15023850     Source Type: Journal    
DOI: 10.3109/00016357.2010.545035     Document Type: Article
Times cited : (22)

References (41)
  • 2
    • 0036869211 scopus 로고    scopus 로고
    • Sublingual atropine for sialorrhea secondary to parkinsonism: A pilot study
    • DOI 10.1002/mds.10276
    • Hyson HC, Johnson A, Jog MS. Sublingual atropine for sialorrhoea secondary to parkinsonism: a pilot study. Mov Disord 2002;17:1318-20. (Pubitemid 36041348)
    • (2002) Movement Disorders , vol.17 , Issue.6 , pp. 1318-1320
    • Hyson, H.C.1    Johnson, A.M.2    Jog, M.S.3
  • 4
    • 36248941872 scopus 로고    scopus 로고
    • Radiotherapy reduces sialorrhea in amyotrophic lateral sclerosis
    • DOI 10.1111/j.1468-1331.2007.01983.x
    • Neppelberg E, Haugen DF, Thorsen L, Tysnes OB. Radiotherapy reduces sialorrhea in amyotrophic lateral sclerosis. Eur J Neurol 2007;14:1373-7. (Pubitemid 350135307)
    • (2007) European Journal of Neurology , vol.14 , Issue.12 , pp. 1373-1377
    • Neppelberg, E.1    Haugen, D.F.2    Thorsen, L.3    Tysnes, O.-B.4
  • 5
    • 59649092908 scopus 로고    scopus 로고
    • Systematic review of the effectiveness of botulinum toxin or radiotherapy for sialorrhoea in patients with amyotrophic lateral sclerosis
    • Stone CA, O'Leary N. Systematic review of the effectiveness of botulinum toxin or radiotherapy for sialorrhoea in patients with amyotrophic lateral sclerosis. J Pain Symptom Manage 2009;37:246-58.
    • (2009) J. Pain Symptom Manage , vol.37 , pp. 246-258
    • Stone, C.A.1    O'Leary, N.2
  • 7
    • 33746668108 scopus 로고    scopus 로고
    • Botulinum toxin improves sialorrhea and quality of living in bulbar amyotrophic lateral sclerosis
    • DOI 10.1002/mus.20545
    • Verma A, Steele J. Botulinum toxin improves sialorrhoea and quality of living in bulbar amyotrophic lateral sclerosis. Muscle Nerve 2006;34:235-7. (Pubitemid 44167807)
    • (2006) Muscle and Nerve , vol.34 , Issue.2 , pp. 235-237
    • Verma, A.1    Steele, J.2
  • 8
    • 0020983675 scopus 로고
    • Secretion rate and buffer effect of resting and stimulated whole saliva as a function of age and sex
    • Heintze U, Birkhed D, Björn H. Secretion rate and buffer effect of resting and stimulated whole saliva as a function of age and sex. Swed Dent J 1983;7:227-8.
    • (1983) Swed Dent. J , vol.7 , pp. 227-228
    • Heintze, U.1    Birkhed, D.2    Björn, H.3
  • 9
    • 85005339907 scopus 로고
    • Salivary flow rate, buffering capacity, and yeast counts in 187 consecutive adult patients from Kuopio, Finland
    • Meurman JH, Rantonen P. Salivary flow rate, buffering capacity, and yeast counts in 187 consecutive adult patients from Kuopio, Finland. Scand J Dent Res 1994;102:229-34.
    • (1994) Scand. J. Dent. Res. , vol.102 , pp. 229-234
    • Meurman, J.H.1    Rantonen, P.2
  • 10
    • 0034198642 scopus 로고    scopus 로고
    • Saliva in health and disease: An appraisal and update
    • Sreebny LM. Saliva in health and disease: an appraisal and update. Int Dent J 2000;50:140-61.
    • (2000) Int. Dent. J , vol.50 , pp. 140-161
    • Sreebny, L.M.1
  • 11
    • 0023695774 scopus 로고
    • Xerostomia part I. Relationship to other oral symptoms and salivary gland hypofunction
    • Sreebny LM, Valdini A. Xerostomia Part I. Relationship to other oral symptoms and salivary gland hypofunction. Oral Surg Oral Med Oral Pathol 1988:66;451-8.
    • (1988) Oral. Surg. Oral. Med. Oral. Pathol. , vol.66 , pp. 451-458
    • Sreebny, L.M.1    Valdini, A.2
  • 12
    • 0014106225 scopus 로고
    • The effect of flow rate and length of stimulation on the protein concentration in human parotid saliva
    • Dawes C. The effect of flow rate and length of stimulation on the protein concentration in human parotid saliva. Arch Oral Biol 1967;12:783-8.
    • (1967) Arch. Oral. Biol. , vol.12 , pp. 783-788
    • Dawes, C.1
  • 13
    • 0014486050 scopus 로고
    • The effect of flow rate and duration of stimulation on the concentration of protein and the main electrolytes in human parotid saliva
    • Dawes C. The effect of flow rate and duration of stimulation on the concentration of protein and the main electrolytes in human parotid saliva. Arch Oral Biol 1969;14:277-94.
    • (1969) Arch. Oral. Biol. , vol.14 , pp. 277-294
    • Dawes, C.1
  • 14
    • 0016273419 scopus 로고
    • The effects of flow rate and duration of stimulation on the concentrations of protein and the main electrolytes in human submandibular saliva
    • Dawes C. The effects of flow rate and duration of stimulation on the concentrations of protein and the main electrolytes in human submandibular saliva. Arch Oral Biol 1974;19:887-95.
    • (1974) Arch. Oral. Biol. , vol.19 , pp. 887-895
    • Dawes, C.1
  • 15
    • 34447343090 scopus 로고    scopus 로고
    • Treatment of sialorrhoea in patients with Parkinson's disease: Best current evidence
    • DOI 10.1097/01.wco.0000280411.57836.aa, PII 0001905220070800000019
    • Molloy L. Treatment of sialorrhoea in patients with Parkinson's disease: best current evidence. Curr Opin Neurol 2007;20:493-8. (Pubitemid 47051999)
    • (2007) Current Opinion in Neurology , vol.20 , Issue.4 , pp. 493-498
    • Molloy, L.1
  • 16
    • 33746476937 scopus 로고    scopus 로고
    • Botulinum toxin in the management of sialorrhoea: A systematic review
    • DOI 10.1111/j.1749-4486.2006.01263.x
    • Lim M, Mace A, Nouraei SA, Sandhu G. Botulinum toxin in the management of sialorrhoea: a systematic review. Clin Otolaryngol 2006;31:267-72. (Pubitemid 44141089)
    • (2006) Clinical Otolaryngology , vol.31 , Issue.4 , pp. 267-272
    • Lim, M.1    Mace, A.2    Reza Nouraei, S.A.3    Sandhu, G.4
  • 17
    • 33645103492 scopus 로고    scopus 로고
    • Botulinum toxin treatment of sialorrhea: Comparing different therapeutic preparations
    • Tan EK. Botulinum toxin treatment of sialorrhea: comparing different therapeutic preparations. Eur J Neurol 2006;13(Suppl 1):60-4.
    • (2006) Eur. J. Neurol. , vol.13 , Issue.1 SUPPL. , pp. 60-64
    • Tan, E.K.1
  • 18
    • 34548317020 scopus 로고    scopus 로고
    • Intraglandular application of botulinum toxin leads to structural and functional changes in rat acinar cells
    • DOI 10.1038/sj.bjp.0707375, PII 0707375
    • Teymoortash A, Sommer F, Mandic R, Schulz S, Bette M, Aumüller G, et al. Intraglandular application of botulinum toxin leads to structural and functional changes in rat acinar cells. Br J Clin Pharmacol 2007;152:161-7. (Pubitemid 47339910)
    • (2007) British Journal of Pharmacology , vol.152 , Issue.1 , pp. 161-167
    • Teymoortash, A.1    Sommer, F.2    Mandic, R.3    Schulz, S.4    Bette, M.5    Aumuller, G.6    Werner, J.A.7
  • 20
    • 4944228569 scopus 로고    scopus 로고
    • Reduction of salivary flow with botulinum toxin: Extended report on 33 patients with drooling, salivary fistulas, and sialadenitis
    • DOI 10.1097/00005537-200410000-00033
    • Ellies M, Gottstein U, Rohrbach-Volland S, Arglebe C, Laskawi R. Reduction of salivary flow with botulinum toxin: extended report on 33 patients with drooling, salivary fistulas, and sialadenitis. Laryngoscope 2004:114;1856-60. (Pubitemid 39332268)
    • (2004) Laryngoscope , vol.114 , Issue.10 , pp. 1856-1860
    • Ellies, M.1    Gottstein, U.2    Rohrbach-Volland, S.3    Arglebe, C.4    Laskawi, R.5
  • 22
    • 0035059822 scopus 로고    scopus 로고
    • Treatment of sialorrhoea with ultrasound guided botulinum toxin type A injection in patients with neurological disorders
    • DOI 10.1136/jnnp.70.4.538
    • Porta M, Gamba M, Bertacchi G, Vaj P. Treatment of sialorrhoea with ultrasound guided botulinum toxin type A injection in patients with neurological disorders. J Neurol Neurosurg Psychiatry 2001;70:538-40. (Pubitemid 32269697)
    • (2001) Journal of Neurology Neurosurgery and Psychiatry , vol.70 , Issue.4 , pp. 538-540
    • Porta, M.1    Gamba, M.2    Bertacchi, G.3    Vaj, P.4
  • 23
    • 0033974106 scopus 로고    scopus 로고
    • Botulinum toxin A as treatment for drooling saliva in PD
    • Pal PK, Calne DB, Calne S, Tsui JK. Botulinum toxin A as treatment for drooling saliva in PD. Neurology 2000;54:244-7. (Pubitemid 30038773)
    • (2000) Neurology , vol.54 , Issue.1 , pp. 244-247
    • Pal, P.K.1    Calne, D.B.2    Calne, S.3    Tsui, J.K.C.4
  • 24
    • 0242662829 scopus 로고    scopus 로고
    • A randomized trial of botulinum toxin A for treatment of drooling
    • Lipp A, Trottenberg T, Schink T, Kupsch A, Arnold G. A randomized trial of botulinum toxin A for treatment of drooling. Neurology 2003;61:1279-81. (Pubitemid 37377556)
    • (2003) Neurology , vol.61 , Issue.9 , pp. 1279-1281
    • Lipp, A.1    Trottenberg, T.2    Schink, T.3    Kupsch, A.4    Arnold, G.5
  • 25
    • 0038422869 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled study to evaluate the efficacy and safety of botulinum toxin type A in the treatment of drooling Parkinsonism
    • DOI 10.1002/mds.10420
    • Mancini F, Zangaglia R, Cristina S, Sommaruga MG, Martignoni E, Nappi G, et al. Double-blind, placebocontrolled study to evaluate the efficacy and safety of botulinum toxin type A in the treatment of drooling in parkinsonism. Mov Disord 2003;8:685-8. (Pubitemid 36790285)
    • (2003) Movement Disorders , vol.18 , Issue.6 , pp. 685-688
    • Mancini, F.1    Zangaglia, R.2    Cristina, S.3    Sommaruga, M.G.4    Martignoni, E.5    Nappi, G.6    Pacchetti, C.7
  • 26
    • 1542315511 scopus 로고    scopus 로고
    • Ultrasound-guided versus 'blind' intraparotid injections of botulinum toxin-A for the treatment of sialorrhoea in patients with Parkinson's disease
    • DOI 10.1016/j.clineuro.2003.10.012, PII S030384670300115X
    • Dogu O, Apaydin D, Sevim S, Talas DU, Aral M. Ultrasound-guided versus 'blind' intraparotid injections of botulinum toxin-A for the treatment of sialorrhoea in patients with Parkinson's disease. Clin Neurol Neurosurg 2004;106:93-6. (Pubitemid 38299270)
    • (2004) Clinical Neurology and Neurosurgery , vol.106 , Issue.2 , pp. 93-96
    • Dogu, O.1    Apaydin, D.2    Sevim, S.3    Talas, D.U.4    Aral, M.5
  • 27
    • 33646925831 scopus 로고    scopus 로고
    • Botulinum toxin type A for drooling in Parkinson's disease: A double-blind, randomized, placebo-controlled study
    • DOI 10.1002/mds.20793
    • Lagalla G, Millevolte M, Capecci M, Provinciali L, Ceravolo MG. Botulinum toxin type A for drooling in Parkinson's disease: a double-blind, randomized, placebocontrolled study. Mov Disord 2006;21:704-7. (Pubitemid 43792756)
    • (2006) Movement Disorders , vol.21 , Issue.5 , pp. 704-707
    • Lagalla, G.1    Millevolte, M.2    Capecci, M.3    Provinciali, L.4    Ceravolo, M.G.5
  • 28
    • 33846579510 scopus 로고    scopus 로고
    • Does botulinum toxin decrease frequency and severity of sialorrhea in Parkinson's disease?
    • DOI 10.1016/j.jns.2006.11.015, PII S0022510X06005387
    • Nobrega AC, Roderigues B, Torres AC, Enzo A, Melo A. Does botulinum toxin decrease frequency and severity of sialorrhoea in Parkinson's disease? J Neurol Sci 2007;253:85-7. (Pubitemid 46185453)
    • (2007) Journal of the Neurological Sciences , vol.253 , Issue.1-2 , pp. 85-87
    • Nobrega, A.C.1    Rodrigues, B.2    Torres, A.C.3    Enzo, A.4    Melo, A.5
  • 30
    • 0028142392 scopus 로고
    • El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis
    • Brooks BR. El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. J Neurol Sci 1994;124(Suppl): 96-107.
    • (1994) J. Neurol. Sci. , vol.124 , Issue.SUPPL. , pp. 96-107
    • Brooks, B.R.1
  • 31
    • 0027337422 scopus 로고
    • Parkinson's Disease Society Brain Bank, London: Overview and research
    • Daniel SE, Lees AJ. Parkinson's Disease Society Brain Bank, London: overview and research. J Neural Transm 1993;39(Suppl): 15-72.
    • (1993) J. Neural. Transm. , vol.39 , Issue.SUPPL. , pp. 15-72
    • Daniel, S.E.1    Lees, A.J.2
  • 32
    • 0020199758 scopus 로고
    • A comparison of whole mouth resting and stimulated salivary measurement procedures
    • Navazesh M, Christensen CM. A comparison of whole mouth resting and stimulated salivary measurement procedures. J Dent Res 1982;61:1158-62.
    • (1982) J. Dent. Res. , vol.61 , pp. 1158-1162
    • Navazesh, M.1    Christensen, C.M.2
  • 34
    • 0035072643 scopus 로고    scopus 로고
    • Relationships between medication intake, complaints of dry mouth, salivary flow rate and composition, and the rate of tooth demineralization in situ
    • DOI 10.1016/S0003-9969(01)00003-6, PII S0003996901000036
    • Bardow A, Nyvad B, Nauntofte B. Relations between medication intake, complaints of dry mouth, saliva flow rate, saliva composition, and the rate of human tooth demineralization in situ. Arch Oral Biol 2001;46:413-23. (Pubitemid 32289671)
    • (2001) Archives of Oral Biology , vol.46 , Issue.5 , pp. 413-423
    • Bardow, A.1    Nyvad, B.2    Nauntofte, B.3
  • 35
    • 23944527141 scopus 로고    scopus 로고
    • Botulinum toxin type A injections: Adverse events reported to the US Food and Drug Administration in therapeutic and cosmetic cases
    • DOI 10.1016/j.jaad.2005.06.011, PII S0190962205019857
    • Coté TR, Mohan AK, Polder JA, Walton MK, Braun MM. Botulinum toxin type A injections: adverse events reported to the US Food and Drug Administration in therapeutic and cosmetic cases. J Am Acad Dermatol 2005;53:407-15. (Pubitemid 41195960)
    • (2005) Journal of the American Academy of Dermatology , vol.53 , Issue.3 , pp. 407-415
    • Cote, T.R.1    Mohan, A.K.2    Polder, J.A.3    Walton, M.K.4    Braun, M.M.5
  • 36
    • 67649866052 scopus 로고    scopus 로고
    • Neuritogenic actions of botulinum neurotoxin A on cultured motor neurons
    • Coffield JA, Yan X. Neuritogenic actions of botulinum neurotoxin A on cultured motor neurons. J Pharmacol Exp Ther 2009;330:352-8.
    • (2009) J. Pharmacol. Exp. Ther. , vol.330 , pp. 352-358
    • Coffield, J.A.1    Yan, X.2
  • 37
    • 0036146348 scopus 로고    scopus 로고
    • Botulinum neurotoxins: From paralysis to recovery of functional neuromuscular transmission
    • DOI 10.1016/S0928-4257(01)00086-9, PII S0928425701000869
    • Meunier FA, Schiavo G, Molgo J. Botulinum neurotoxins: from paralysis to recovery of functional neuromuscular transmission. J Physiol Paris 2002;96:105-13. (Pubitemid 34087038)
    • (2002) Journal of Physiology Paris , vol.96 , Issue.1-2 , pp. 105-113
    • Meunier, F.A.1    Schiavo, G.2    Molgo, J.3
  • 38
    • 0001769854 scopus 로고
    • The solubility of tooth substance in relation to the composition of saliva
    • Schmidt-Nielsen B. The solubility of tooth substance in relation to the composition of saliva. Acta Odontol Scand 1946;7(Suppl 2):1-88.
    • (1946) Acta Odontol. Scand. , vol.7 , Issue.2 SUPPL. , pp. 1-88
    • Schmidt-Nielsen, B.1
  • 39
    • 0042232391 scopus 로고    scopus 로고
    • Synaptic transmission: Inhibition of neurotransmitter release by botulinum toxins
    • Dolly O. Synaptic transmission: inhibition of neurotransmitter release by botulinum toxins. Headache 2003;43(Suppl 1):16-24.
    • (2003) Headache , vol.43 , Issue.1 SUPPL. , pp. 16-24
    • Dolly, O.1
  • 40
    • 0038678697 scopus 로고    scopus 로고
    • Secretion of electrolytes and water by salivary glands
    • Garrett JR, Ekström J, Anderson LC, editors, Frontiers of oral biology, Basel, Switzerland: Karger
    • Poulsen JH. Secretion of electrolytes and water by salivary glands. In: Garrett JR, Ekström J, Anderson LC, editors. Glandular mechanisms of salivary secretion. Frontiers of oral biology, Vol. 10. Basel, Switzerland: Karger; 1998. p. 55-72.
    • (1998) Glandular Mechanisms of Salivary Secretion , vol.10 , pp. 55-72
    • Poulsen, J.H.1
  • 41
    • 0001940280 scopus 로고    scopus 로고
    • Secretory protein synthesis and constitutive (vesicular) secretion by salivary glands
    • Garrett JR, Ekström J, Anderson LC, editors, Basel, Switzerland: Karger
    • Proctor GB. Secretory protein synthesis and constitutive (vesicular) secretion by salivary glands. In: Garrett JR, Ekström J, Anderson LC, editors. Glandular mechanisms of salivary secretion. Frontiers of oral biology, Vol. 10. Basel, Switzerland: Karger, 1998. p. 73-88.
    • (1998) Glandular Mechanisms of Salivary Secretion. Frontiers of Oral. Biology , vol.10 , pp. 73-88
    • Proctor, G.B.1


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