-
1
-
-
33847739736
-
Selective tumor cell targeting using low-affinity, multivalent interactions
-
DOI 10.1021/cb6003788
-
Carlson, C. B., Mowery, P., Owen, R. M., Dykhuizen, E. C., and Kiessling, L. L. (2007) Selective tumor cell targeting using low-affinity, multivalent interactions ACS Chem. Biol. 2, 119-127 (Pubitemid 47490233)
-
(2007)
ACS Chemical Biology
, vol.2
, Issue.2
, pp. 119-127
-
-
Calson, C.B.1
Mowery, P.2
Owen, R.M.3
Dykhuizen, E.C.4
Kiessling, L.L.5
-
2
-
-
33846295955
-
3 integrin
-
DOI 10.1002/cbic.200600339
-
3 integrin ChemBioChem. 8, 68-82 (Pubitemid 46121574)
-
(2007)
ChemBioChem
, vol.8
, Issue.1
, pp. 68-82
-
-
Owen, R.M.1
Carlson, C.B.2
Xu, J.3
Mowery, P.4
Fasella, E.5
Kiessling, L.L.6
-
3
-
-
72249105755
-
Chemical control over immune recognition: A class of antibody-recruiting small molecules that target prostate cancer
-
Murelli, R. P., Zhang, A. X., Michel, J., Jorgensen, W. L., and Spiegel, D. A. (2009) Chemical control over immune recognition: a class of antibody-recruiting small molecules that target prostate cancer J. Am. Chem. Soc. 131, 17090-17092
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 17090-17092
-
-
Murelli, R.P.1
Zhang, A.X.2
Michel, J.3
Jorgensen, W.L.4
Spiegel, D.A.5
-
4
-
-
63149182641
-
Instant immunity through chemically programmable vaccination and covalent self-assembly
-
Popkov, M., Gonzalez, B., Sinha, S. C., and Barbas, C. F. (2009) Instant immunity through chemically programmable vaccination and covalent self-assembly Proc. Natl. Acad. Sci. U.S.A. 106, 4378-4383
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 4378-4383
-
-
Popkov, M.1
Gonzalez, B.2
Sinha, S.C.3
Barbas, C.F.4
-
5
-
-
1942503277
-
Folate receptor-targeted immunotherapy of cancer: Mechanism and therapeutic potential
-
DOI 10.1016/j.addr.2004.01.009, PII S0169409X04000195
-
Lu, Y. J., Sega, E., Leamon, C. P., and Low, P. S. (2004) Folate receptor-targeted immunotherapy of cancer: mechanism and therapeutic potential Adv. Drug Delivery Rev. 56, 1161-1176 (Pubitemid 38496513)
-
(2004)
Advanced Drug Delivery Reviews
, vol.56
, Issue.8
, pp. 1161-1176
-
-
Lu, Y.1
Sega, E.2
Leamon, C.P.3
Low, P.S.4
-
6
-
-
0026560664
-
Antibody targeting to bacterial-cells using receptor-specific ligands
-
Bertozzi, C. R. and Bednarski, M. D. (1992) Antibody targeting to bacterial-cells using receptor-specific ligands J. Am. Chem. Soc. 114, 2242-2245
-
(1992)
J. Am. Chem. Soc.
, vol.114
, pp. 2242-2245
-
-
Bertozzi, C.R.1
Bednarski, M.D.2
-
7
-
-
0001194625
-
A receptor-mediated immune-response using synthetic glycoconjugates
-
Bertozzi, C. R. and Bednarski, M. D. (1992) A receptor-mediated immune-response using synthetic glycoconjugates J. Am. Chem. Soc. 114, 5543-5546
-
(1992)
J. Am. Chem. Soc.
, vol.114
, pp. 5543-5546
-
-
Bertozzi, C.R.1
Bednarski, M.D.2
-
8
-
-
13944283259
-
Protein heterodimerization through ligand-bridged multivalent pre-oraanization: Enhancing ligand binding toward both protein targets
-
DOI 10.1021/ja043817r
-
Liu, J. Y., Zhang, Z. S., Tan, X. J., Hol, W. G. J., Verlinde, C., and Fan, E. K. (2005) Protein heterodimerization through ligand-bridged multivalent pre-organization: Enhancing ligand binding toward both protein targets J. Am. Chem. Soc. 127, 2044-2045 (Pubitemid 40270498)
-
(2005)
Journal of the American Chemical Society
, vol.127
, Issue.7
, pp. 2044-2045
-
-
Liu, J.1
Zhang, Z.2
Tan, X.3
Hol, W.G.J.4
Verlinde, C.L.M.J.5
Fan, E.6
-
9
-
-
33645859599
-
Promotion of opsonization by antibodies and phagocytosis of Gram-positive bacteria by a bifunctional polyacrylamide
-
Krishnamurthy, V. M., Quinton, L. J., Estroff, L. A., Metallo, S. J., Isaacs, J. M., Mizgerd, J. P., and Whitesides, G. M. (2006) Promotion of opsonization by antibodies and phagocytosis of Gram-positive bacteria by a bifunctional polyacrylamide Biomaterials 27, 3663-3674
-
(2006)
Biomaterials
, vol.27
, pp. 3663-3674
-
-
Krishnamurthy, V.M.1
Quinton, L.J.2
Estroff, L.A.3
Metallo, S.J.4
Isaacs, J.M.5
Mizgerd, J.P.6
Whitesides, G.M.7
-
10
-
-
0038465268
-
Redirecting the immune-response - Ligand-mediated immunogenicity
-
Shokat, K. M. and Schultz, P. G. (1991) Redirecting the immune-response - ligand-mediated immunogenicity J. Am. Chem. Soc. 113, 1861-1862
-
(1991)
J. Am. Chem. Soc.
, vol.113
, pp. 1861-1862
-
-
Shokat, K.M.1
Schultz, P.G.2
-
11
-
-
1642299756
-
Design and synthesis of alpha Gal-conjugated peptide T20 as novel antiviral agent for HIV-immunotargeting
-
Naicker, K. P., Li, H. G., Heredia, A., Song, H. J., and Wang, L. X. (2004) Design and synthesis of alpha Gal-conjugated peptide T20 as novel antiviral agent for HIV-immunotargeting Org. Biomol. Chem. 2, 660-664
-
(2004)
Org. Biomol. Chem.
, vol.2
, pp. 660-664
-
-
Naicker, K.P.1
Li, H.G.2
Heredia, A.3
Song, H.J.4
Wang, L.X.5
-
12
-
-
50449087950
-
Neutralization of HIV-1 by redirection of natural antibodies
-
Perdomo, M. F., Levi, M., Sallberg, M., and Vahlne, A. (2008) Neutralization of HIV-1 by redirection of natural antibodies Proc. Natl. Acad. Sci. U.S.A. 105, 12515-12520
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 12515-12520
-
-
Perdomo, M.F.1
Levi, M.2
Sallberg, M.3
Vahlne, A.4
-
13
-
-
70450188855
-
An antibody-recruiting small molecule that targets HIV gp120
-
Parker, C. G., Domaoal, R. A., Anderson, K. S., and Spiegel, D. A. (2009) An antibody-recruiting small molecule that targets HIV gp120 J. Am. Chem. Soc. 131, 16392-16394
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 16392-16394
-
-
Parker, C.G.1
Domaoal, R.A.2
Anderson, K.S.3
Spiegel, D.A.4
-
14
-
-
26444601733
-
Heterobifunctional multivalent inhibitor-adaptor mediates specific aggregation between Shiga toxin and a pentraxin
-
DOI 10.1021/ol051529+
-
Solomon, D., Kitov, P. I., Paszkiewicz, E., Grant, G. A., Sadowska, J. M., and Bundle, D. R. (2005) Heterobifunctional multivalent inhibitor-adaptor mediates specific aggregation between Shiga toxin and a pentraxin Org. Lett. 7, 4369-4372 (Pubitemid 41436649)
-
(2005)
Organic Letters
, vol.7
, Issue.20
, pp. 4369-4372
-
-
Solomon, D.1
Kitov, P.I.2
Paszkiewicz, E.3
Grant, G.A.4
Sadowska, J.M.5
Bundle, D.R.6
-
15
-
-
38349033369
-
An entropically efficient supramolecular inhibition strategy for Shiga toxins
-
Kitov, P. I., Lipinski, T., Paszkiewicz, E., Solomon, D., Sadowska, J. M., Grant, G. A., Mulvey, G. L., Kitova, E. N., Klassen, J. S., Armstrong, G. D., and Bundle, D. R. (2008) An entropically efficient supramolecular inhibition strategy for Shiga toxins Angew. Chem., Int. Ed. Engl. 47, 672-676
-
(2008)
Angew. Chem., Int. Ed. Engl.
, vol.47
, pp. 672-676
-
-
Kitov, P.I.1
Lipinski, T.2
Paszkiewicz, E.3
Solomon, D.4
Sadowska, J.M.5
Grant, G.A.6
Mulvey, G.L.7
Kitova, E.N.8
Klassen, J.S.9
Armstrong, G.D.10
Bundle, D.R.11
-
16
-
-
55949097146
-
In vivo supramolecular templating enhances the activity of multivalent ligands: A potential therapeutic against the Escherichia coli O157 AB(5) toxins
-
Kitov, P. I., Mulvey, G. L., Griener, T. P., Lipinski, T., Solomon, D., Paszkiewicz, E., Jacobson, J. M., Sadowska, J. M., Suzuki, M., Yamamura, K. I., Armstrong, G. D., and Bundle, D. R. (2008) In vivo supramolecular templating enhances the activity of multivalent ligands: A potential therapeutic against the Escherichia coli O157 AB(5) toxins Proc. Natl. Acad. Sci. U.S.A. 105, 16837-16842
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 16837-16842
-
-
Kitov, P.I.1
Mulvey, G.L.2
Griener, T.P.3
Lipinski, T.4
Solomon, D.5
Paszkiewicz, E.6
Jacobson, J.M.7
Sadowska, J.M.8
Suzuki, M.9
Yamamura, K.I.10
Armstrong, G.D.11
Bundle, D.R.12
-
17
-
-
7444221875
-
Harnessing chaperons to generate small-molecule inhibitors of amyloid β aggregation
-
DOI 10.1126/science.1101262
-
Gestwicki, J. E., Crabtree, G. R., and Graef, I. A. (2004) Harnessing chaperones to generate small-molecule inhibitors of amyloid beta aggregation Science 306, 865-869 (Pubitemid 39446994)
-
(2004)
Science
, vol.306
, Issue.5697
, pp. 865-869
-
-
Gestwicki, J.E.1
Crabtree, G.R.2
Graef, I.A.3
-
18
-
-
0034628502
-
Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands
-
DOI 10.1038/35001095
-
Kitov, P. I., Sadowska, J. M., Mulvey, G., Armstrong, G. D., Ling, H., Pannu, N. S., Read, R. J., and Bundle, D. R. (2000) Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands Nature 403, 669-672 (Pubitemid 30104009)
-
(2000)
Nature
, vol.403
, Issue.6770
, pp. 669-672
-
-
Kitov, P.I.1
Sadowska, J.M.2
Mulvey, G.3
Armstrong, G.D.4
Ling, H.5
Pannu, N.S.6
Read, R.J.7
Bundle, D.R.8
-
19
-
-
33947602811
-
Siglecs and their roles in the immune system
-
DOI 10.1038/nri2056, PII NRI2056
-
Crocker, P. R., Paulson, J. C., and Varki, A. (2007) Siglecs and their roles in the immune system Nat. Rev. Immunol. 7, 255-266 (Pubitemid 46480955)
-
(2007)
Nature Reviews Immunology
, vol.7
, Issue.4
, pp. 255-266
-
-
Crocker, P.R.1
Paulson, J.C.2
Varki, A.3
-
20
-
-
33745662565
-
B cells move to centre stage: Novel opportunities for autoimmune disease treatment
-
DOI 10.1038/nrd2085, PII N2085
-
Browning, J. L. (2006) B cells move to centre stage: novel opportunities for autoimmune disease treatment Nat. Rev. Drug Discovery 5, 564-576 (Pubitemid 43971191)
-
(2006)
Nature Reviews Drug Discovery
, vol.5
, Issue.7
, pp. 564-576
-
-
Browning, J.L.1
-
21
-
-
33747753195
-
High-affinity ligand probes of CD22 overcome the threshold set by cis ligands to allow for binding, endocytosis, and killing of B cells
-
Collins, B. E., Blixt, O., Han, S. F., Duong, B., Li, H. Y., Nathan, J. K., Bovin, N., and Paulson, J. C. (2006) High-affinity ligand probes of CD22 overcome the threshold set by cis ligands for binding, endocytosis, and killing of B cells J. Immunol. 177, 2994-3003 (Pubitemid 44277815)
-
(2006)
Journal of Immunology
, vol.177
, Issue.5
, pp. 2994-3003
-
-
Collins, B.E.1
Blixt, O.2
Han, S.3
Duong, B.4
Li, H.5
Nathan, J.K.6
Bovin, N.7
Paulson, J.C.8
-
22
-
-
28444493924
-
Homomultimeric complexes of CD22 in B cells revealed by protein-glycan cross-linking
-
Han, S., Collins, B. E., Bengtson, P., and Paulson, J. C. (2005) Homomultimeric complexes of CD22 in B cells revealed by protein-glycan cross-linking Nat. Chem. Biol. 1, 93-97
-
(2005)
Nat. Chem. Biol.
, vol.1
, pp. 93-97
-
-
Han, S.1
Collins, B.E.2
Bengtson, P.3
Paulson, J.C.4
-
23
-
-
45249120121
-
Bifunctional CD22 ligands use multimeric immunoglobulins as protein scaffolds in assembly of immune complexes on B cells
-
DOI 10.1021/ja802008q
-
OReilly, M. K., Collins, B. E., Han, S., Liao, L., Rillahan, C., Kitov, P. I., Bundle, D. R., and Paulson, J. C. (2008) Bifunctional CD22 ligands use multimeric immunoglobulins as protein scaffolds in assembly of immune complexes on B cells J. Am. Chem. Soc. 130, 7736-7745 (Pubitemid 351842137)
-
(2008)
Journal of the American Chemical Society
, vol.130
, Issue.24
, pp. 7736-7745
-
-
O'Reilly, M.K.1
Collins, B.E.2
Han, S.3
Liao, L.4
Rillahan, C.5
Kitov, P.I.6
Bundle, D.R.7
Paulson, J.C.8
-
24
-
-
41849083065
-
On-virus construction of polyvalent glycan ligands for cell-surface receptors
-
DOI 10.1021/ja077801n
-
Kaltgrad, E., OReilly, M. K., Liao, L. A., Han, S. F., Paulson, J. C., and Finn, M. G. (2008) On-virus construction of polyvalent glycan ligands for cell-surface receptors J. Am. Chem. Soc. 130, 4578-4579 (Pubitemid 351500082)
-
(2008)
Journal of the American Chemical Society
, vol.130
, Issue.14
, pp. 4578-4579
-
-
Kaltgrad, E.1
O'Reilly, M.K.2
Liao, L.3
Han, S.4
Paulson, J.C.5
Finn, M.G.6
-
25
-
-
0030977640
-
Immunons revisited: Binding of multivalent antigens to b cells
-
DOI 10.1016/S0161-5890(96)00096-X, PII S016158909600096X
-
Sulzer, B. and Perelson, A. S. (1997) Immunons revisited: binding of multivalent antigens to B cells Mol. Immunol. 34, 63-74 (Pubitemid 27244536)
-
(1997)
Molecular Immunology
, vol.34
, Issue.1
, pp. 63-74
-
-
Sulzer, B.1
Perelson, A.S.2
-
26
-
-
0034753172
-
T-cell activation by soluble MHC oligomers can be described by a two-parameter binding model
-
Stone, J. D., Cochran, J. R., and Stern, L. J. (2001) T-cell activation by soluble MHC oligomers can be described by a two-parameter binding model Biophys. J. 81, 2547-2557 (Pubitemid 33020043)
-
(2001)
Biophysical Journal
, vol.81
, Issue.5
, pp. 2547-2557
-
-
Stone, J.D.1
Cochran, J.R.2
Stern, L.J.3
-
27
-
-
0036462596
-
Thermodynamic studies of lectin-carbohydrate interactions by isothermal titration calorimetry
-
DOI 10.1021/cr000401x
-
Dam, T. K. and Brewer, C. F. (2002) Thermodynamic studies of lectin-carbohydrate interactions by isothermal titration calorimetry Chem. Rev. 102, 387-429 (Pubitemid 35381635)
-
(2002)
Chemical Reviews
, vol.102
, Issue.2
, pp. 387-429
-
-
Dam, T.K.1
Brewer, C.F.2
-
28
-
-
0034640419
-
Binding of multivalent carbohydrates to concanavalin A and dioclea grandiflora lectin
-
Dam, T. K., Roy, R., Das, S. K., Oscarson, S., and Brewer, C. F. (2000) Binding of multivalent carbohydrates to concanavalin A and dioclea grandiflora lectin J. Biol. Chem. 275, 14223-14230
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 14223-14230
-
-
Dam, T.K.1
Roy, R.2
Das, S.K.3
Oscarson, S.4
Brewer, C.F.5
-
29
-
-
78449262678
-
Enhancement of plant and bacterial lectin binding affinities by three-dimensional organized cluster glycosides constructed on helical poly(phenylacetylene) backbones
-
Otsuka, I., Blanchard, B., Borsali, R., Imberty, A., and Kakuchi, T. (2010) Enhancement of plant and bacterial lectin binding affinities by three-dimensional organized cluster glycosides constructed on helical poly(phenylacetylene) backbones ChemBioChem 11, 2399-2408
-
(2010)
ChemBioChem
, vol.11
, pp. 2399-2408
-
-
Otsuka, I.1
Blanchard, B.2
Borsali, R.3
Imberty, A.4
Kakuchi, T.5
|