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Volumn 2, Issue 3, 2011, Pages 521-530

Synthesis and utility of fluorogenic acetoxymethyl ethers

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL SCIENCE; CELLULAR ESTERASE; FLUOROGENICS; IN-VITRO; LOW BACKGROUND; PHENOLIC HYDROXYL GROUP; PHENYL ESTERS; PHENYL ETHERS; RESORUFIN; SMALL MOLECULES;

EID: 79955010307     PISSN: 20416520     EISSN: 20416539     Source Type: Journal    
DOI: 10.1039/c0sc00466a     Document Type: Article
Times cited : (82)

References (59)
  • 5
    • 0019829560 scopus 로고
    • R. Y. Tsien, Nature, 1981, 290, 527-528.
    • (1981) Nature , vol.290 , pp. 527-528
    • Tsien, R.Y.1
  • 22
    • 0043165887 scopus 로고
    • P. D. Taylor, Talanta, 1995, 42, 243-248.
    • (1995) Talanta , vol.42 , pp. 243-248
    • Taylor, P.D.1
  • 34
    • 79955593317 scopus 로고    scopus 로고
    • We use the term "apparent" because full fluorescence manifestation requires the removal of two AM ether moieties
    • We use the term "apparent" because full fluorescence manifestation requires the removal of two AM ether moieties.
  • 55
    • 33947094308 scopus 로고    scopus 로고
    • Notes
    • We note that the values of kcat/KM for the four AM ethers (4a, 4b, 6, and 9) are (106 ± 40)% those of the analogous acetate esters (2a, 2b, 7, and 10, respectively). The insignificant difference between these values is consistent with the breakdown of the hemiacetal formed initially upon AM-ether hydrolysis being rapid (as expected, see: L. H. Funderburk, L. Aldwin and W. P. Jencks, J. Am. Chem. Soc., 1978, 100, 5444-5459) and not limiting the rate of fluorescence generation.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.