메뉴 건너뛰기




Volumn 214, Issue 8, 2011, Pages 1300-1306

Hibernating above the permafrost: Effects of ambient temperature and season on expression of metabolic genes in liver and brown adipose tissue of arctic ground squirrels

Author keywords

Arctic ground squirrel; Fuel substrate; Hibernation; Metabolism; Real time PCR; Thermogenesis; Torpor

Indexed keywords

ANIMAL; ARCTIC; ARTICLE; BODY TEMPERATURE; BROWN ADIPOSE TISSUE; ENERGY METABOLISM; GENE EXPRESSION REGULATION; GENETICS; HIBERNATION; LIVER; METABOLISM; PHYSIOLOGY; PRINCIPAL COMPONENT ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCIURIDAE; SEASON; TEMPERATURE;

EID: 79955009080     PISSN: 00220949     EISSN: None     Source Type: Journal    
DOI: 10.1242/jeb.052159     Document Type: Article
Times cited : (31)

References (46)
  • 1
    • 3442876969 scopus 로고    scopus 로고
    • Normalization of real-time quantitative reverse transcription-PCR data: A model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets
    • DOI 10.1158/0008-5472.CAN-04-0496
    • Andersen, C. L., Jensen, J. L. and Orntoft, T. F. (2004). Normalization of real-time quantitative reverse transcription-PCR data: a model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets. Cancer Res. 64, 5245-5250. (Pubitemid 39006544)
    • (2004) Cancer Research , vol.64 , Issue.15 , pp. 5245-5250
    • Andersen, C.L.1    Jensen, J.L.2    Orntoft, T.F.3
  • 2
    • 0024475071 scopus 로고
    • Freeze avoidance in a mammal: Body temperatures below 0°C in an arctic hibernator
    • Barnes, B. M. (1989). Freeze avoidance in a mammal: body temperatures below 0°C in an arctic hibernator. Science 244, 1593-1595.
    • (1989) Science , vol.244 , pp. 1593-1595
    • Barnes, B.M.1
  • 3
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini, Y. and Hochberg, Y. (1995). Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. R. Stat. Soc. Ser. B 57, 289-300.
    • (1995) J. R. Stat. Soc. Ser. B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 4
    • 0000365405 scopus 로고    scopus 로고
    • Annual cycle of body composition and hibernation in free-living Arctic ground squirrels
    • Buck, C. L. and Barnes, B. M. (1999a). Annual cycle of body composition and hibernation in free-living arctic ground squirrels. J. Mammal. 80, 430-442. (Pubitemid 129588651)
    • (1999) Journal of Mammalogy , vol.80 , Issue.2 , pp. 430-442
    • Buck, C.L.1    Barnes, B.M.2
  • 5
    • 0000980548 scopus 로고    scopus 로고
    • Temperatures of hibernacula and changes in body composition of arctic ground squirrels over winter
    • Buck, C. L. and Barnes, B. M. (1999b). Temperatures of hibernacula and changes in body composition of arctic ground squirrels over winter. J. Mammal. 80, 1264-1276. (Pubitemid 129588598)
    • (1999) Journal of Mammalogy , vol.80 , Issue.4 , pp. 1264-1276
    • Buck, C.L.1    Barnes, B.M.2
  • 7
    • 0141528621 scopus 로고    scopus 로고
    • Mammalian hibernation: Cellular and molecular responses to depressed metabolism and low temperature
    • Carey, H. V., Andrews, M. T. and Martin, S. L. (2003). Mammalian hibernation: cellular and molecular responses to depressed metabolism and low temperature. Physiol. Rev. 83, 1153-1181. (Pubitemid 37222270)
    • (2003) Physiological Reviews , vol.83 , Issue.4 , pp. 1153-1181
    • Carey, H.V.1    Andrews, M.T.2    Martin, S.L.3
  • 8
    • 33645118571 scopus 로고    scopus 로고
    • Flux control exerted by mitochondrial outer membrane carnitine palmitoyltransferase over β-oxidation, ketogenesis and tricarboxylic acid cycle activity in hepatocytes isolated from rats in different metabolic states
    • Drynan, L., Auant, P. A. and Zammit, V. A. (1996). Flux control exerted by mitochondrial outer membrane carnitine palmitoyltransferase over β-oxidation, ketogenesis and tricarboxylic acid cycle activity in hepatocytes isolated from rats in different metabolic states. Biochem. J. 323, 119-122.
    • (1996) Biochem. J. , vol.323 , pp. 119-122
    • Drynan, L.1    Auant, P.A.2    Zammit, V.A.3
  • 9
    • 5644273100 scopus 로고    scopus 로고
    • Quantitative analysis of liver protein expression during hibernation in the golden-mantled ground squirrel
    • DOI 10.1074/mcp.M400042-MCP200
    • Epperson, L. E., Dahl, T. A. and Martin, S. L. (2004). Quantitative analysis of liver protein expression during hibernation in the golden-mantled ground squirrel. Mol. Cell. Proteomics 3, 920-933. (Pubitemid 39369203)
    • (2004) Molecular and Cellular Proteomics , vol.3 , Issue.9 , pp. 920-933
    • Epperson, L.E.1    Dahl, T.A.2    Martin, S.L.3
  • 10
    • 75449114212 scopus 로고    scopus 로고
    • Seasonal proteomic changes reveal molecular adaptations to preserve and replenish liver proteins during ground squirrel hibernation
    • Epperson, L. E., Rose, J. C., Carey, H. V. and Martin, S. L. (2010). Seasonal proteomic changes reveal molecular adaptations to preserve and replenish liver proteins during ground squirrel hibernation. Am. J. Physiol. Regul. Integr. Comp. Physiol. 298, R329-R340.
    • (2010) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.298
    • Epperson, L.E.1    Rose, J.C.2    Carey, H.V.3    Martin, S.L.4
  • 11
    • 0029738496 scopus 로고    scopus 로고
    • How do woodchucks (Marmota monax) cope with harsh winter conditions?
    • Ferron, J. (1996). How do woodchucks (Maromota monax) cope with harsh winter conditions? J. Mammal. 77, 412-416. (Pubitemid 26309495)
    • (1996) Journal of Mammalogy , vol.77 , Issue.2 , pp. 412-416
    • Ferron, J.1
  • 12
    • 33644975004 scopus 로고    scopus 로고
    • RNA integrity and the effect on the real-time qRTPCR performance
    • Fleige, S. and Pfaffl, M. W. (2006). RNA integrity and the effect on the real-time qRTPCR performance. Mol. Aspects Med. 27, 126-139.
    • (2006) Mol. Aspects Med. , vol.27 , pp. 126-139
    • Fleige, S.1    Pfaffl, M.W.2
  • 14
    • 0014766386 scopus 로고
    • Cyclic changes in carbohydrate concentrations during hibernation in the arctic ground squirrel
    • Galster, W. and Morrison, P. R. (1970). Cyclic changes in carbohydrate concentrations during hibernation in the arctic ground squirrel. Am. J. Physiol. 218, 1228-1232.
    • (1970) Am. J. Physiol. , vol.218 , pp. 1228-1232
    • Galster, W.1    Morrison, P.R.2
  • 15
    • 0016667250 scopus 로고
    • Gluconeogenesis in arctic ground squirrels between periods of hibernation
    • Galster, W. and Morrison, P. R. (1975). Gluconeogenesis in arctic ground squirrels between periods of hibernation. Am. J. Physiol. 228, 325-330.
    • (1975) Am. J. Physiol. , vol.228 , pp. 325-330
    • Galster, W.1    Morrison, P.R.2
  • 16
    • 2342501936 scopus 로고    scopus 로고
    • Metabolic rate and body temperature reduction during hibernation and daily torpor
    • DOI 10.1146/annurev.physiol.66.032102.115105
    • Geiser, F. (2004). Metabolic rate and body temperature reduction during hibernation and daily torpor. Annu. Rev. Physiol. 66, 239-274. (Pubitemid 40614445)
    • (2004) Annual Review of Physiology , vol.66 , pp. 239-274
    • Geiser, F.1
  • 17
    • 0029189099 scopus 로고
    • Hibernation versus daily torpor in mammals and birds: Physiological variables and classification of torpor patterns
    • Geiser, F. and Ruf, T. (1995). Hibernation versus daily torpor in mammals and birds: physiological variables and classification of torpor patterns. Physiol. Zool. 68, 935-966. (Pubitemid 3017960)
    • (1995) Physiological Zoology , vol.68 , Issue.6 , pp. 935-966
    • Geiser, F.1    Ruf, T.2
  • 18
    • 79954991928 scopus 로고
    • The physiology of hibernation
    • Gorer, P. A. (1930). The physiology of hibernation. Biol. Rev. 5, 213-230.
    • (1930) Biol. Rev. , vol.5 , pp. 213-230
    • Gorer, P.A.1
  • 19
    • 0037095624 scopus 로고    scopus 로고
    • The translation state of differentially expressed mRNAs in the hibernating 13-lined ground squirrel (Spermophilus tridecemlineatus)
    • DOI 10.1016/S0003-9861(02)00048-6, PII S0003986102000486
    • Hittel, D. and Storey, K. B. (2002). The translation state of differentially expressed mRNAs in the hibernating 13-lined ground squirrel (Spermophilus tridecemlineatus). Arch. Biochem. Biophys. 401, 244-254. (Pubitemid 34848627)
    • (2002) Archives of Biochemistry and Biophysics , vol.401 , Issue.2 , pp. 244-254
    • Hittel, D.1    Storey, K.B.2
  • 20
    • 70349773842 scopus 로고    scopus 로고
    • Energetics of arousal episodes in hibernating arctic ground squirrels
    • Karpovich, S. A., Tøien, O., Buck, C. L. and Barnes, B. M. (2009). Energetics of arousal episodes in hibernating arctic ground squirrels. J. Comp. Physiol. B 179, 691-700.
    • (2009) J. Comp. Physiol. B , vol.179 , pp. 691-700
    • Karpovich, S.A.1    Tøien, O.2    Buck, C.L.3    Barnes, B.M.4
  • 21
    • 0024936028 scopus 로고
    • Annual cycle of energy and time expenditure in a golden-mantled ground squirrel population
    • Kenagy, G. J., Sharbaugh, S. M. and Nagy, K. A. (1989). Annual cycle of energy and time expenditure in a golden mantled ground squirrel population. Oecologia 78, 269-282. (Pubitemid 20426416)
    • (1989) Oecologia , vol.78 , Issue.2 , pp. 269-282
    • Kenagy, G.J.1    Sharbaugh, S.M.2    Nagy, K.A.3
  • 22
    • 0033838865 scopus 로고    scopus 로고
    • MRNA stability and polysome loss in hibernating arctic ground squirrels (Spermophilus parryii)
    • DOI 10.1128/MCB.20.17.6374-6379.2000
    • Knight, J. E., Narus, E. N., Martin, S. L., Jacobson, A., Barnes, B. M. and Boyer, B. B. (2000). mRNA stability and polysome loss in hibernating arctic ground squirrels (Spermophilus parryii). Mol. Cell. Biol. 20, 6374-6379. (Pubitemid 30650224)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.17 , pp. 6374-6379
    • Knight, J.E.1    Narus, E.N.2    Martin, S.L.3    Jacobson, A.4    Barnes, B.M.5    Boyer, B.B.6
  • 23
    • 0034520194 scopus 로고    scopus 로고
    • Differential expression of ACAT1 and ACAT2 among cells within liver, intestine, kidney, and adrenal of nonhuman primates
    • Lee, R. G., Willingham, M. C., Davis, M. A., Skinner, K. A. and Rude, R. L. (2000). Differential expression of ACAT1 and ACAT2 among cells within liver, intestine, kidney, and adrenal of nonhuman primates. J. Lipid Res. 41, 1991-2001. (Pubitemid 32038994)
    • (2000) Journal of Lipid Research , vol.41 , Issue.12 , pp. 1991-2001
    • Lee, R.G.1    Willingham, M.C.2    Davis, M.A.3    Skinner, K.A.4    Rudel, L.L.5
  • 24
    • 78649776000 scopus 로고    scopus 로고
    • Body temperature patterns during hibernation in a free-living Alaska marmot (Marmota broweri)
    • Lee, T. N., Barnes, B. M. and Buck, C. L. (2009). Body temperature patterns during hibernation in a free-living Alaska marmot (Marmota broweri). Ethol. Ecol. Evol. 21, 403-413.
    • (2009) Ethol. Ecol. Evol. , vol.21 , pp. 403-413
    • Lee, T.N.1    Barnes, B.M.2    Buck, C.L.3
  • 25
    • 46449131504 scopus 로고    scopus 로고
    • Simultaneous collection of body temperature and activity data in burrowing mammals: A new technique
    • Long, R. A., Hut, R. A. and Barnes, B. M. (2007). Simultaneous collection of body temperature and activity data in burrowing mammals: a new technique. J. Wildl. Manage. 71, 1375-1379.
    • (2007) J. Wildl. Manage. , vol.71 , pp. 1375-1379
    • Long, R.A.1    Hut, R.A.2    Barnes, B.M.3
  • 26
    • 0000372786 scopus 로고
    • Physiology of hibernation in mammals
    • Lyman, P. C. and Chatfield, P. O. (1955). Physiology of hibernation in mammals. Physiol. Rev. 35, 403-425.
    • (1955) Physiol. Rev. , vol.35 , pp. 403-425
    • Lyman, P.C.1    Chatfield, P.O.2
  • 27
    • 0022177333 scopus 로고
    • Intracellular pH in hibernation and respiratory acidosis in the European hamster
    • Malan, A., Rodeau, J. L. and Daull, F. (1985). Intracellular pH in hibernation and respiratory acidosis in the European hamster. J. Comp. Physiol. B 156, 251-258.
    • (1985) J. Comp. Physiol. B , vol.156 , pp. 251-258
    • Malan, A.1    Rodeau, J.L.2    Daull, F.3
  • 28
    • 0027063744 scopus 로고
    • Sexual differences in over-winter torpor patterns of Richardson's ground squirrels in natural hibernacula
    • Michener, G. R. (1992). Sexual differences in over-winter torpor patterns of Richardson's ground squirrels in natural hibernacula. Oecologia 89, 397-406.
    • (1992) Oecologia , vol.89 , pp. 397-406
    • Michener, G.R.1
  • 29
    • 33845897343 scopus 로고    scopus 로고
    • Evidence for a reduced transcriptional state during hibernation in ground squirrels
    • DOI 10.1016/j.cryobiol.2006.08.002, PII S0011224006001179
    • Morin, P., Jr and Storey, K. B. (2006). Evidence for a reduced transcriptional state during hibernation in ground squirrels. Cryobiology 53, 310-318. (Pubitemid 46026754)
    • (2006) Cryobiology , vol.53 , Issue.3 , pp. 310-318
    • Morin Jr., P.1    Storey, K.B.2
  • 30
    • 0025524789 scopus 로고
    • Relationships between respiratory quotient and metabolic rate during entry to and arousal from daily torpor in deer mice (Peromyscus maniculatus
    • Nestler, J. R. (1990). Relationships between respiratory quotient and metabolic rate during entry to and arousal from daily torpor in deer mice (Peromyscus maniculatus). Physiol. Zool. 63, 504-514.
    • (1990) Physiol. Zool. , vol.63 , pp. 504-514
    • Nestler, J.R.1
  • 31
    • 78650792278 scopus 로고    scopus 로고
    • Muscle plasticity in hibernating ground squirrels (Spermophilus lateralis) is induced by seasonal, but not lowtemperature, mechanisms
    • Nowell, M. M., Choi, H. and Rourke, B. C. (2010). Muscle plasticity in hibernating ground squirrels (Spermophilus lateralis) is induced by seasonal, but not lowtemperature, mechanisms. J. Comp. Physiol. B 181, 147-164.
    • (2010) J. Comp. Physiol. B , vol.181 , pp. 147-164
    • Nowell, M.M.1    Choi, H.2    Rourke, B.C.3
  • 32
    • 77952497876 scopus 로고    scopus 로고
    • Identification of qRT-PCR reference genes for analysis of opioid gene expression in a hibernator
    • Otis, J. P., Ackermann, L. W., Denning, G. M. and Carey, H. V. (2010). Identification of qRT-PCR reference genes for analysis of opioid gene expression in a hibernator. J. Comp. Physiol. B 180, 619-629.
    • (2010) J. Comp. Physiol. B , vol.180 , pp. 619-629
    • Otis, J.P.1    Ackermann, L.W.2    Denning, G.M.3    Carey, H.V.4
  • 33
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl, M. W. (2001). A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29, e45.
    • (2001) Nucleic Acids Res. , vol.29
    • Pfaffl, M.W.1
  • 34
    • 40449141013 scopus 로고    scopus 로고
    • What is principal component analysis?
    • DOI 10.1038/nbt0308-303, PII NBT0308303
    • Ringnér, M. (2008). What is principal component analysis? Nat. Biotechnol. 26, 303-304. (Pubitemid 351355122)
    • (2008) Nature Biotechnology , vol.26 , Issue.3 , pp. 303-304
    • Ringner, M.1
  • 35
    • 34548822408 scopus 로고    scopus 로고
    • Quantitative analysis of liver metabolites in three stages of the circannual hibernation cycle in 13-lined ground squirrels by NMR
    • DOI 10.1152/physiolgenomics.00028.2007
    • Serkova, N. J., Rose, J. C., Epperson, L. E., Carey, H. V. and Martin, S. L. (2007). Quantitative analysis of liver metabolites in three stages of the circannual hibernation cycle in 13-lined ground squirrels by NMR. Physiol. Genomics 31, 15-24. (Pubitemid 47443844)
    • (2007) Physiological Genomics , vol.31 , Issue.1 , pp. 15-24
    • Serkova, N.J.1    Rose, J.C.2    Epperson, L.E.3    Carey, H.V.4    Martin, S.L.5
  • 37
    • 0025836229 scopus 로고
    • Morphometric and metabolic indices of disuse in muscles of hibernating ground squirrels
    • Steffen, J. M., Koebel, D. A., Musacchia, X. J. and Milsom, W. K. (1991). Morphometric and metabolic indices of disuse in muscles of hibernating ground squirrels. Comp. Biochem. Physiol. 99B, 815-819.
    • (1991) Comp. Biochem. Physiol. , vol.99 B , pp. 815-819
    • Steffen, J.M.1    Koebel, D.A.2    Musacchia, X.J.3    Milsom, W.K.4
  • 38
    • 1442291120 scopus 로고    scopus 로고
    • Metabolic rate depression in animals: Transcriptional and translational controls
    • DOI 10.1017/S1464793103006195
    • Storey, K. B. and Storey, J. M. (2004). Metabolic rate depression in animals: transcriptional and translational controls. Biol. Rev. 79, 207-233. (Pubitemid 38282052)
    • (2004) Biological Reviews of the Cambridge Philosophical Society , vol.79 , Issue.1 , pp. 207-233
    • Storey, K.B.1    Storey, J.M.2
  • 39
    • 0035202902 scopus 로고    scopus 로고
    • Translational initiation is uncoupled from elongation at 18°C during mammalian hibernation
    • Van Breukelen, F. and Martin, S. (2001). Translational initiation is uncoupled from elongation at 18°C during mammalian hibernation. Am. J. Physiol. Regul. Integr. Comp. Physiol. 281, R1374-R1379.
    • (2001) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.281
    • Van Breukelen, F.1    Martin, S.2
  • 41
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • research
    • Vandesompele, J., De Preter, K., Pattyn, F., Poppe, B., Van Roy, N., De Paepe, A. and Speleman, F. (2002). Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 3, research0034.1-0034.11.
    • (2002) Genome Biol. , vol.3 , pp. 00341-003411
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6    Speleman, F.7
  • 42
    • 0026327675 scopus 로고
    • Disuse atrophy in the hibernating golden-mantled ground squirrel, Spermophilus lateralis
    • Wickler, S. J., Hoyt, D. F. and Van Breukelen, F. (1991). Disuse atrophy in the hibernating golden-mantled ground squirrel, Spermophilus lateralis. Am. J. Physiol. Regul. Integr. Comp. Physiol. 261, 1214-1217.
    • (1991) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.261 , pp. 1214-1217
    • Wickler, S.J.1    Hoyt, D.F.2    Van Breukelen, F.3
  • 44
    • 33645787507 scopus 로고    scopus 로고
    • Detection of differential gene expression in brown adipose tissue of hibernating arctic ground squirrels with mouse microarrays
    • Yan, J., Burman, A., Nichols, C., Alila, L., Showe, L. C., Showe, M. K., Boyer, B. B., Barnes, B. M. and Marr, T. G. (2006). Detection of differential gene expression in brown adipose tissue of hibernating arctic ground squirrels with mouse microarrays. Physiol. Genomics 25, 346-353.
    • (2006) Physiol. Genomics , vol.25 , pp. 346-353
    • Yan, J.1    Burman, A.2    Nichols, C.3    Alila, L.4    Showe, L.C.5    Showe, M.K.6    Boyer, B.B.7    Barnes, B.M.8    Marr, T.G.9
  • 45
    • 38749146491 scopus 로고    scopus 로고
    • Modulation of gene expression in hibernating arctic ground squirrels
    • DOI 10.1152/physiolgenomics.00075.2007
    • Yan, J., Barnes, B. M., Kohl, F. and Marr, T. G. (2008). Modulation of gene expression in hibernating arctic ground squirrels. Physiol. Genomics 32, 170-181. (Pubitemid 351186324)
    • (2008) Physiological Genomics , vol.32 , Issue.2 , pp. 170-181
    • Yan, J.1    Barnes, B.M.2    Kohl, F.3    Marr, T.G.4
  • 46
    • 0025624336 scopus 로고
    • Hibernating patterns of free-ranging Columbian ground squirrels
    • Young, P. J. (1990). Hibernating patterns of free-ranging Columbian ground squirrels. Oecologia 83, 504-511.
    • (1990) Oecologia , vol.83 , pp. 504-511
    • Young, P.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.