-
2
-
-
33947101019
-
Patterns of somatic mutation in human cancer genomes
-
Greenman C., Stephens P., Smith R., et al. Patterns of somatic mutation in human cancer genomes. Nature 2007, 446:153-158.
-
(2007)
Nature
, vol.446
, pp. 153-158
-
-
Greenman, C.1
Stephens, P.2
Smith, R.3
-
3
-
-
34247537858
-
Utility of circulating B-RAF DNA mutation in serum for monitoring melanoma patients receiving biochemotherapy
-
Shinozaki M., O'Day S.J., Kitago M., et al. Utility of circulating B-RAF DNA mutation in serum for monitoring melanoma patients receiving biochemotherapy. Clin Cancer Res 2007, 13:2068-2074.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2068-2074
-
-
Shinozaki, M.1
O'Day, S.J.2
Kitago, M.3
-
4
-
-
18144409161
-
Clinical significance of BRAF mutations in metastatic melanoma
-
Chang D.Z., Panageas K.S., Osman I., Polsky D., Busam K., Chapman P.B. Clinical significance of BRAF mutations in metastatic melanoma. J Transl Med 2004, 2:46.
-
(2004)
J Transl Med
, vol.2
, pp. 46
-
-
Chang, D.Z.1
Panageas, K.S.2
Osman, I.3
Polsky, D.4
Busam, K.5
Chapman, P.B.6
-
5
-
-
16844385347
-
Melanoma genetics and the development of rational therapeutics
-
Chudnovsky Y., Khavari P.A., Adams A.E. Melanoma genetics and the development of rational therapeutics. J Clin Invest 2005, 115:813-824.
-
(2005)
J Clin Invest
, vol.115
, pp. 813-824
-
-
Chudnovsky, Y.1
Khavari, P.A.2
Adams, A.E.3
-
6
-
-
79951947484
-
BRAF p.Val600Glu (V600E) Testing for assessment of treatment options in metastatic colorectal cancer
-
Lea A., Allingham-Hawkins D., Levine S. BRAF p.Val600Glu (V600E) Testing for assessment of treatment options in metastatic colorectal cancer. PLoS Curr 2010, 2:RRN1187.
-
(2010)
PLoS Curr
, vol.2
-
-
Lea, A.1
Allingham-Hawkins, D.2
Levine, S.3
-
7
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies H., Bignell G.R., Cox C., et al. Mutations of the BRAF gene in human cancer. Nature 2002, 417:949-954.
-
(2002)
Nature
, vol.417
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
-
8
-
-
75449083561
-
Molecular diagnostics and predictors in thyroid cancer
-
Nikiforova M.N., Nikiforov Y.E. Molecular diagnostics and predictors in thyroid cancer. Thyroid 2009, 19:1351-1361.
-
(2009)
Thyroid
, vol.19
, pp. 1351-1361
-
-
Nikiforova, M.N.1
Nikiforov, Y.E.2
-
9
-
-
33947230256
-
Distinct clinical and pathological features are associated with the BRAF(T1799A(V600E)) mutation in primary melanoma
-
Liu W., Kelly J.W., Trivett M., et al. Distinct clinical and pathological features are associated with the BRAF(T1799A(V600E)) mutation in primary melanoma. J Invest Dermatol 2007, 127:900-905.
-
(2007)
J Invest Dermatol
, vol.127
, pp. 900-905
-
-
Liu, W.1
Kelly, J.W.2
Trivett, M.3
-
10
-
-
77954218212
-
BRAF as therapeutic target in melanoma
-
Wellbrock C., Hurlstone A. BRAF as therapeutic target in melanoma. Biochem Pharmacol 2010, 80:561-567.
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 561-567
-
-
Wellbrock, C.1
Hurlstone, A.2
-
11
-
-
4344584872
-
B-RAF is a therapeutic target in melanoma
-
Karasarides M., Chiloeches A., Hayward R., et al. B-RAF is a therapeutic target in melanoma. Oncogene 2004, 23:6292-6298.
-
(2004)
Oncogene
, vol.23
, pp. 6292-6298
-
-
Karasarides, M.1
Chiloeches, A.2
Hayward, R.3
-
12
-
-
67651246671
-
Phase I study of PLX4032: proof of concept for V600E BRAF mutation as a therapeutic target in human cancer
-
(abstr 9000) s
-
Flaherty K., Puzanov I., Sosman J. Phase I study of PLX4032: proof of concept for V600E BRAF mutation as a therapeutic target in human cancer. J Clin Oncol 2009, 27(15s). (abstr 9000).
-
(2009)
J Clin Oncol
, vol.27
, Issue.15
-
-
Flaherty, K.1
Puzanov, I.2
Sosman, J.3
-
13
-
-
77949354563
-
PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells
-
Halaban R., Zhang W., Bacchiocchi A., et al. PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells. Pigment Cell Melanoma Res 2010, 23:190-200.
-
(2010)
Pigment Cell Melanoma Res
, vol.23
, pp. 190-200
-
-
Halaban, R.1
Zhang, W.2
Bacchiocchi, A.3
-
14
-
-
43249116705
-
Replacing PCR with COLD-PCR enriches variant DNA sequences and redefines the sensitivity of genetic testing
-
Li J., Wang L., Mamon H., Kulke M.H., Berbeco R., Makrigiorgos G.M. Replacing PCR with COLD-PCR enriches variant DNA sequences and redefines the sensitivity of genetic testing. Nat Med 2008, 14:579-584.
-
(2008)
Nat Med
, vol.14
, pp. 579-584
-
-
Li, J.1
Wang, L.2
Mamon, H.3
Kulke, M.H.4
Berbeco, R.5
Makrigiorgos, G.M.6
-
15
-
-
0033872068
-
Detection of gene amplification in archival breast cancer specimens by laser-assisted microdissection and quantitative real-time polymerase chain reaction
-
Lehmann U., Glöckner S., Kleeberger W., von Wasielewski H.F., H.Kreipe Detection of gene amplification in archival breast cancer specimens by laser-assisted microdissection and quantitative real-time polymerase chain reaction. Am J Pathol 2000, 156:1855-1864.
-
(2000)
Am J Pathol
, vol.156
, pp. 1855-1864
-
-
Lehmann, U.1
Glöckner, S.2
Kleeberger, W.3
von Wasielewski, H.F.4
Kreipe, H.5
-
16
-
-
34548757329
-
Application of a BRAF pyrosequencing assay for mutation detection and copy number analysis in malignant melanoma
-
Spittle C., Ward M.R., Nathanson K.L., et al. Application of a BRAF pyrosequencing assay for mutation detection and copy number analysis in malignant melanoma. J Mol Diagn 2007, 9:464-471.
-
(2007)
J Mol Diagn
, vol.9
, pp. 464-471
-
-
Spittle, C.1
Ward, M.R.2
Nathanson, K.L.3
-
17
-
-
48649092117
-
High-resolution melting analysis for rapid detection of KRAS, BRAF, and PIK3CA gene mutations in colorectal cancer
-
Simi L., Pratesi N., Vignoli M., et al. High-resolution melting analysis for rapid detection of KRAS, BRAF, and PIK3CA gene mutations in colorectal cancer. Am J Clin Pathol 2008, 130:247-253.
-
(2008)
Am J Clin Pathol
, vol.130
, pp. 247-253
-
-
Simi, L.1
Pratesi, N.2
Vignoli, M.3
-
19
-
-
79551595779
-
Targeting BRAF for patients with melanoma
-
doi:10.1038/sj.bjc.6606030
-
Arkenau H.T., Kefford R., Long G.V. Targeting BRAF for patients with melanoma. Br J Cancer 2010, doi:10.1038/sj.bjc.6606030.
-
(2010)
Br J Cancer
-
-
Arkenau, H.T.1
Kefford, R.2
Long, G.V.3
-
20
-
-
77956792325
-
The use of COLD-PCR and high-resolution melting analysis improves the limit of detection of KRAS and BRAF mutations in colorectal cancer
-
Mancini I., Santucci C., Sestini R., et al. The use of COLD-PCR and high-resolution melting analysis improves the limit of detection of KRAS and BRAF mutations in colorectal cancer. J Mol Diagn 2010, 12:705-711.
-
(2010)
J Mol Diagn
, vol.12
, pp. 705-711
-
-
Mancini, I.1
Santucci, C.2
Sestini, R.3
-
21
-
-
68249089660
-
Application of COLD-PCR for improved detection of KRAS mutations in clinical samples
-
Zuo Z., Chen S.S., Chandra P.K., et al. Application of COLD-PCR for improved detection of KRAS mutations in clinical samples. Mod Pathol 2009, 22:1023-1031.
-
(2009)
Mod Pathol
, vol.22
, pp. 1023-1031
-
-
Zuo, Z.1
Chen, S.S.2
Chandra, P.K.3
-
22
-
-
70350704817
-
Two-round coamplification at lower denaturation temperature-PCR (COLD-PCR)-based sanger sequencing identifies a novel spectrum of low-level mutations in lung adenocarcinoma
-
Li J., Milbury C.A., Li C., Makrigiorgos G.M. Two-round coamplification at lower denaturation temperature-PCR (COLD-PCR)-based sanger sequencing identifies a novel spectrum of low-level mutations in lung adenocarcinoma. Hum Mutat 2009, 30:1583-1590.
-
(2009)
Hum Mutat
, vol.30
, pp. 1583-1590
-
-
Li, J.1
Milbury, C.A.2
Li, C.3
Makrigiorgos, G.M.4
|