A new automated urine fentanyl immunoassay: Technical performance and clinical utility for monitoring fentanyl compliance

Clinica Chimica Acta

Volumn 412, Issue 11-12, 2011, Pages 946-951

  Snyder, Marion L ^a   Jarolim, Petr ^a   Melanson, Stacy E F ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Chronic pain; Drugs of abuse screening; Fentanyl; Immunalysis; Immunoassay; Opioid compliance monitoring

Indexed keywords

FENTANYL; NARCOTIC ANALGESIC AGENT;

ANALGESIC AGENT ABUSE; ARTICLE; AUTOANALYSIS; CHRONIC PAIN; CLINICAL EVALUATION; CONTROLLED STUDY; CROSS REACTION; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; ENZYME IMMUNOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; INSTRUMENT VALIDATION; INTERMETHOD COMPARISON; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PATIENT COMPLIANCE; PATIENT MONITORING; PRESCRIPTION; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; URINALYSIS;

ANALGESICS, OPIOID; AUTOMATION; CHRONIC PAIN; DRUG PRESCRIPTIONS; FENTANYL; HUMANS; IMMUNOENZYME TECHNIQUES; MEDICATION ADHERENCE; URINALYSIS;

EID: 79955006758     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2011.01.029     Document Type: Article

References (17)

1. Mao C.L., Zientek K.D., Colahan P.T., et al. Development of an enzyme-linked immunosorbent assay for fentanyl and applications of fentanyl antibody-coated nanoparticles for sample preparation. J Pharm Biomed Anal 2006, 41(4):1332-1341.
2. Poklis A., Backer R. Urine concentrations of fentanyl and norfentanyl during application of Duragesic transdermal patches. J Anal Toxicol 2004, 28(6):422-425.
3. Trescot A.M., Glaser S.E., Hansen H., Benyamin R., Patel S., Manchikanti L. Effectiveness of opioids in the treatment of chronic non-cancer pain. Pain Physician 2008, 11(2 Suppl):S181-S200.
4. Nelson L., Schwaner R. Transdermal fentanyl: pharmacology and toxicology. J Med Toxicol 2009, 5(4):230-241.
5. Melanson S.E., Kredlow M.I., Jarolim P. Analysis and interpretation of drug testing results from patients on chronic pain therapy: a clinical laboratory perspective. Clin Chem Lab Med 2009, 47(8):971-976.
6. Cone E.J., Caplan Y.H., Black D.L., Robert T., Moser F. Urine drug testing of chronic pain patients: licit and illicit drug patterns. J Anal Toxicol 2008, 32(8):530-543.
7. Trescot A.M., Helm S., Hansen H., et al. Opioids in the management of chronic non-cancer pain: an update of American Society of the Interventional Pain Physicians' (ASIPP) guidelines. Pain Physician 2008, 11(2 Suppl):S5-S62.
8. Trescot A.M., Boswell M.V., Atluri S.L., et al. Opioid guidelines in the management of chronic non-cancer pain. Pain Physician 2006, 9(1):1-39.
9. Hammett-Stabler C.A., Pesce A.J., Cannon D.J. Urine drug screening in the medical setting. Clin Chim Acta 2002, 315(1-2):125-135.
10. Heit H.A., Gourlay D.L. Urine drug testing in pain medicine. J Pain Symptom Manage 2004, 27(3):260-267.
11. Katz N., Fanciullo G.J. Role of urine toxicology testing in the management of chronic opioid therapy. Clin J Pain 2002, 18(4 Suppl):S76-S82.
12. Manchikanti L., Manchukonda R., Pampati V., et al. Does random urine drug testing reduce illicit drug use in chronic pain patients receiving opioids?. Pain Physician 2006, 9(2):123-129.
13. Nafziger A.N., Bertino J.S. Utility and application of urine drug testing in chronic pain management with opioids. Clin J Pain 2009, 25(1):73-79.
14. Huynh N.H., Tyrefors N., Ekman L., Johansson M. Determination of fentanyl in human plasma and fentanyl and norfentanyl in human urine using LC-MS/MS. J Pharm Biomed Anal 2005, 37(5):1095-1100.
15. Musshoff F., Trafkowski J., Kuepper U., Madea B. An automated and fully validated LC-MS/MS procedure for the simultaneous determination of 11 opioids used in palliative care, with 5 of their metabolites. J Mass Spectrom 2006, 41(5):633-640.
16. Baselt R.C. Disposition of toxic drugs and chemicals in man 2008, Biomedical Publications, Foster City, CA. eighth ed.
17. Wang G., Huynh K., Barhate R., et al. Development of a homogenous immunoassay for the detection of fentanyl in urine. Forensic Sci Int 2010, 206(1-3):127-131.