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Volumn 57, Issue 4, 2011, Pages 505-512

The effect of ezetimibe and simvastatin on monocyte cytokine release in patients with isolated hypercholesterolemia

Author keywords

Cytokines; hypercholesterolemia; hypolipidemic agents; monocytes; systemic inflammation

Indexed keywords

APOLIPOPROTEIN B; C REACTIVE PROTEIN; CHOLESTEROL; EZETIMIBE; EZETIMIBE PLUS SIMVASTATIN; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERLEUKIN 1BETA; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MONOCYTE CHEMOTACTIC PROTEIN 1; PLACEBO; SIMVASTATIN; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

EID: 79955005698     PISSN: 01602446     EISSN: 15334023     Source Type: Journal    
DOI: 10.1097/FJC.0b013e318211703b     Document Type: Article
Times cited : (32)

References (33)
  • 1
    • 63249101518 scopus 로고    scopus 로고
    • Novel nonstatin strategies to lower low-density lipoprotein cholesterol
    • Davidson H. Novel nonstatin strategies to lower low-density lipoprotein cholesterol. Curr Atheroscler Rep. 2009;11:67-70.
    • (2009) Curr Atheroscler Rep , vol.11 , pp. 67-70
    • Davidson, H.1
  • 2
    • 49649108596 scopus 로고    scopus 로고
    • Ezetimibe, a selective inhibitor of the transport of cholesterol
    • Miura S, Saku K. Ezetimibe, a selective inhibitor of the transport of cholesterol. Intern Med. 2008;47:1165-1170.
    • (2008) Intern Med , vol.47 , pp. 1165-1170
    • Miura, S.1    Saku, K.2
  • 4
    • 77649196152 scopus 로고    scopus 로고
    • Ezetimibe ameliorates metabolic disorders and microalbuminuria in patients with hypercholesterolemia
    • Yagi S, Akaike M, Aihara K, et al. Ezetimibe ameliorates metabolic disorders and microalbuminuria in patients with hypercholesterolemia. JAtheroscler Thromb. 2010;17:173-180.
    • (2010) JAtheroscler Thromb. , vol.17 , pp. 173-180
    • Yagi, S.1    Akaike, M.2    Aihara, K.3
  • 5
    • 77952674608 scopus 로고    scopus 로고
    • Effect of ezetimibe on hepatic fat, inflammatory markers, and apolipoprotein B-100 kinetics in insulin-resistant obese subjects on a weight loss diet
    • Chan DC, Watts GF, Gan SK, et al. Effect of ezetimibe on hepatic fat, inflammatory markers, and apolipoprotein B-100 kinetics in insulin-resistant obese subjects on a weight loss diet. Diabetes Care. 2010;33: 1134-1139.
    • (2010) Diabetes Care. , vol.33 , pp. 1134-1139
    • Chan, D.C.1    Watts, G.F.2    Gan, S.K.3
  • 6
    • 77954587552 scopus 로고    scopus 로고
    • Synergistic effect of simvastatin and ezetimibe on lipid and pro-inflammatory profiles in pre-diabetic subjects
    • Kater AL, Batista MC, Ferreira SR. Synergistic effect of simvastatin and ezetimibe on lipid and pro-inflammatory profiles in pre-diabetic subjects. Diabetol Metab Syndr. 2010;2:34.
    • (2010) Diabetol Metab Syndr. , vol.2 , pp. 34
    • Kater, A.L.1    Batista, M.C.2    Ferreira, S.R.3
  • 7
    • 77952292502 scopus 로고    scopus 로고
    • Improved endothelial function with simvastatin but unchanged insulin sensitivity with simvastatin or ezetimibe
    • Kater AL, Batista MC, Ferreira SR. Improved endothelial function with simvastatin but unchanged insulin sensitivity with simvastatin or ezetimibe. Metabolism. 2010;59:921-926.
    • (2010) Metabolism. , vol.59 , pp. 921-926
    • Kater, A.L.1    Batista, M.C.2    Ferreira, S.R.3
  • 8
    • 77957560282 scopus 로고    scopus 로고
    • Effects of ezetimibe add-on to statin therapy on adipokine production in patients with metabolic syndrome and stable vascular disease
    • Gupta M, Szmitko PE, Tsigoulis M, et al. Effects of ezetimibe add-on to statin therapy on adipokine production in patients with metabolic syndrome and stable vascular disease. J Cardiovasc Pharmacol. 2010;56:241-245.
    • (2010) J Cardiovasc Pharmacol. , vol.56 , pp. 241-245
    • Gupta, M.1    Szmitko, P.E.2    Tsigoulis, M.3
  • 9
    • 45149097674 scopus 로고    scopus 로고
    • Effects of fluvastatin extended-release (80 mg) alone and in combination with ezetimibe (10 mg) on low-density lipoprotein cholesterol and inflammatory parameters in patients with primary hypercholesterolemia: A 12-week, multicenter, randomized, open-label, parallel-group study
    • DOI 10.1016/j.linthera.2008.01.013, PII S0149291808000611
    • Alvarez-Sala LA, Cachofeiro V, Masana L, et al. Effects of fluvastatin extended-release (80 mg) alone and in combination with ezetimibe (10 mg) on low-density lipoprotein cholesterol and inflammatory parameters in patients with primary hypercholesterolemia: a 12-week, multicenter, randomized, open-label, parallel-group study. Clin Ther. 2008;30:84-97. (Pubitemid 351834727)
    • (2008) Clinical Therapeutics , vol.30 , Issue.1 , pp. 84-97
    • Alvarez-Sala, L.A.1    Cachofeiro, V.2    Masana, L.3    Suarez, C.4    Pinilla, B.5    Plana, N.6    Trias, F.7    Moreno, M.A.8    Gambus, G.9    Lahera, V.10    Pinto, X.11
  • 11
    • 33645912053 scopus 로고    scopus 로고
    • Ezetimib influences the expression of raft-associated antigens in human monocytes
    • Orsó E, Werner T, Wolf Z, et al. Ezetimib influences the expression of raft-associated antigens in human monocytes. CytometryA. 2006;69:206-208.
    • (2006) CytometryA , vol.69 , pp. 206-208
    • Orsó, E.1    Werner, T.2    Wolf, Z.3
  • 12
    • 68749102069 scopus 로고    scopus 로고
    • Ezetimibe reduces plaque inflammation in a rabbit model of atherosclerosis and inhibits monocyte migration in addition to its lipid-lowering effect
    • Gómez-Garre D, Muñoz-Pacheco P, González-Rubio ML, et al. Ezetimibe reduces plaque inflammation in a rabbit model of atherosclerosis and inhibits monocyte migration in addition to its lipid-lowering effect. Br J Pharmacol. 2009;156:1218-1227
    • (2009) Br J Pharmacol , vol.156 , pp. 1218-1227
    • Gómez-Garre, D.1    Muñoz-Pacheco, P.2    González-Rubio, M.L.3
  • 13
    • 0037031061 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: A randomised placebo-controlled trial
    • Heart Protection Study Collaborative Group
    • Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet. 2002;360:7-22.
    • (2002) Lancet , vol.360 , pp. 7-22
  • 15
    • 15744406065 scopus 로고    scopus 로고
    • Effect of monthly atorvastatin and fenofibrate treatment on monocyte chemoattractant protein-1 release in patients with primary mixed dyslipidemia
    • DOI 10.1097/01.fjc.0000156821.50457.32
    • Okopien B, Krysiak R, Haberka M, et al. Effect of monthly atorvastatin and fenofibrate treatment on monocyte chemoattractant protein-1 release in patients with primary hypercholesterolemia. J Cardiovasc Pharmacol. 2005;45:314-320. (Pubitemid 40411286)
    • (2005) Journal of Cardiovascular Pharmacology , vol.45 , Issue.4 , pp. 314-320
    • Okopien, B.1    Krysiak, R.2    Haberka, M.3    Herman, Z.S.4
  • 16
    • 24344489423 scopus 로고    scopus 로고
    • Monocyte release of tumor necrosis factor-α and interleukin-1β in primary type IIa and IIb dyslipidemic patients treated with statins or fibrates
    • DOI 10.1097/01.fjc.0000175455.46245.c8
    • Okopień B, Krysiak R, Kowalski J, et al. Monocyte release of tumor necrosis factor-alpha and interleukin-1beta in primary type IIa and IIb dyslipidemic patients treated with statins or fibrates. J Cardiovasc Pharmacol. 2005;46:377-386. (Pubitemid 41262842)
    • (2005) Journal of Cardiovascular Pharmacology , vol.46 , Issue.3 , pp. 377-386
    • Okopien, B.1    Krysiak, R.2    Kowalski, J.3    Madej, A.4    Belowski, D.5    Zielinski, M.6    Herman, Z.S.7
  • 18
    • 52649120889 scopus 로고    scopus 로고
    • SEAS Investigators. Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis
    • Rossebø AB, Pedersen TR, Boman K, et al; SEAS Investigators. Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis. N EnglJ Med. 2008;359:1343-1356.
    • (2008) N EnglJ Med , vol.359 , pp. 1343-1356
    • Rossebø, A.B.1    Pedersen, T.R.2    Boman, K.3
  • 19
    • 11144313064 scopus 로고    scopus 로고
    • Pathobiology of atherosclerosis\a brief review
    • Kher N, Marsh JD. Pathobiology of atherosclerosis\a brief review. Semin Thromb Hemost. 2004;30:665-672.
    • (2004) Semin Thromb Hemost , vol.30 , pp. 665-672
    • Kher, N.1    Marsh, J.D.2
  • 20
    • 33645891172 scopus 로고    scopus 로고
    • Cytokines in atherosclerosis: Pathogenic and regulatory pathways
    • Tedgui A, Mallat Z. Cytokines in atherosclerosis: pathogenic and regulatory pathways. Physiol Rev. 2006;86:515-581.
    • (2006) Physiol Rev , vol.86 , pp. 515-581
    • Tedgui, A.1    Mallat, Z.2
  • 21
    • 67849088725 scopus 로고    scopus 로고
    • Inflammatory mechanisms in atherosclerosis
    • Hansson GK. Inflammatory mechanisms in atherosclerosis. J Thromb Haemost. 2009;7(suppl 1):328-331.
    • (2009) J Thromb Haemost , vol.7 , Issue.SUPPL. 1 , pp. 328-331
    • Hansson, G.K.1
  • 22
    • 65949117636 scopus 로고    scopus 로고
    • Macrophages: Promising targets for the treatment of atherosclerosis
    • Wilson HM, Barker RN, Erwig LP. Macrophages: promising targets for the treatment of atherosclerosis. Curr Vasc Pharmacol. 2009;7:234-243.
    • (2009) Curr Vasc Pharmacol , vol.7 , pp. 234-243
    • Wilson, H.M.1    Barker, R.N.2    Erwig, L.P.3
  • 23
    • 33751181868 scopus 로고    scopus 로고
    • Inflammatory biomarkers in stable atherosclerosis
    • Kinlay S, Egido J. Inflammatory biomarkers in stable atherosclerosis. Am J Cardiol. 2006;98:P2-P8.
    • (2006) Am J Cardiol , vol.98
    • Kinlay, S.1    Egido, J.2
  • 24
    • 39649116931 scopus 로고    scopus 로고
    • Inflammatory biomarkers and risks ofmyocardial infarction, stroke, diabetes, and total mortality: Implications for longevity
    • Ridker PM. Inflammatory biomarkers and risks ofmyocardial infarction, stroke, diabetes, and total mortality: implications for longevity. Nutr Rev. 2007;65(2):S253-S259.
    • (2007) Nutr Rev , vol.65 , Issue.2
    • Ridker, P.M.1
  • 25
    • 78649388724 scopus 로고    scopus 로고
    • The effect of simvastatin on lymphocyte secretory function in patients with impaired fasting glucose
    • Krysiak R, Okopien B. The effect of simvastatin on lymphocyte secretory function in patients with impaired fasting glucose. J Cardiovasc Pharmacol. 2010;56:491-497.
    • (2010) J Cardiovasc Pharmacol. , vol.56 , pp. 491-497
    • Krysiak, R.1    Okopien, B.2
  • 26
    • 17844410923 scopus 로고    scopus 로고
    • Dose-comparison study of the combination of ezetimibe and simvastatin (Vytorin) versus atorvastatin in patients with hypercholesterolemia: The Vytorin Versus Atorvastatin (VYVA) Study
    • DOI 10.1016/j.ahj.2004.11.023
    • Ballantyne CM, Abate N, Yuan Z, et al. Dose-comparison study of the combination of ezetimibe and simvastatin (Vytorin) versus atorvastatin in patients with hypercholesterolemia: The Vytorin Versus Atorvastatin (VYVA) study Am Heart J. 2005;149:464-473. (Pubitemid 40585409)
    • (2005) American Heart Journal , vol.149 , Issue.3 , pp. 464-473
    • Ballantyne, C.M.1    Abate, N.2    Yuan, Z.3    King, T.R.4    Palmisano, J.5
  • 28
    • 66149156588 scopus 로고    scopus 로고
    • Statin and ezetimibe combination therapy in cardiovascular disease
    • Dembowski E, Davidson MH. Statin and ezetimibe combination therapy in cardiovascular disease. Curr Opin EndocrinolDiabetes Obes. 2009;16:183-188.
    • (2009) Curr Opin EndocrinolDiabetes Obes , vol.16 , pp. 183-188
    • Dembowski, E.1    Davidson, M.H.2
  • 29
    • 38049175023 scopus 로고    scopus 로고
    • Statins: A new insight into their mechanisms of action and consequent pleiotropic effects
    • Jasinska M, Owczarek J, Orszulak-Michalak D. Statins: a new insight into their mechanisms of action and consequent pleiotropic effects. Pharmacol Rep. 2007;59:483-499.
    • (2007) Pharmacol Rep , vol.59 , pp. 483-499
    • Jasinska, M.1    Owczarek, J.2    Orszulak-Michalak, D.3
  • 30
    • 56749106312 scopus 로고    scopus 로고
    • Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein
    • JUPITER Study Group
    • Ridker PM, Danielson E, Fonseca FA, et al; JUPITER Study Group. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med. 2008;359:2195-2207.
    • (2008) N Engl J Med , vol.359 , pp. 2195-2207
    • Ridker, P.M.1    Danielson, E.2    Fonseca, F.A.3
  • 31
    • 20044366995 scopus 로고    scopus 로고
    • High dose atorvastatin associated with worse glycemic control: A PROVE-IT TIMI 22 substudy
    • Sabatine MS, Wiviott SD, Morrow DA. High dose atorvastatin associated with worse glycemic control: a PROVE-IT TIMI 22 substudy. Circulation. 2004;110(suppl):S834.
    • (2004) Circulation , vol.110 , Issue.SUPPL.
    • Sabatine, M.S.1    Wiviott, S.D.2    Morrow, D.A.3
  • 32
    • 56349119861 scopus 로고    scopus 로고
    • Influence of pitavastatin on glucose tolerance in patients with type 2 diabetes mellitus
    • Yamakawa T, Takano T, Tanaka S, et al. Influence of pitavastatin on glucose tolerance in patients with type 2 diabetes mellitus. JAtheroscler Thromb. 2008;15:269-275.
    • (2008) JAtheroscler Thromb , vol.15 , pp. 269-275
    • Yamakawa, T.1    Takano, T.2    Tanaka, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.