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Volumn , Issue 1, 2011, Pages

Pulmonary inhalation aerosols for targeted antibiotics drug delivery

Author keywords

[No Author keywords available]

Indexed keywords

ACETONE; ACETYLCYSTEINE; ALCOHOL; AMIKACIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; AMMONIA; ANTIBIOTIC AGENT; ARIKACE; ASCORBIC ACID; AZITHROMYCIN; AZTREONAM; AZTREONAM LYSINE; BAY 416551; BAYQ 3939; BENZALKONIUM CHLORIDE; CAPREOMYCIN; CETYLPYRIDINIUM SALT; CHLORBUTOL; CIPROFLOXACIN; CITRIC ACID; COLISTIN; CRYOFLUORANE; DICHLORODIFLUOROMETHANE; EDETATE DISODIUM; GLYCOPEPTIDE; LEVOFLOXACIN; MACROLIDE; MONOBACTAM DERIVATIVE; MOXIFLOXACIN; MP 376; POLYPEPTIDE ANTIBIOTIC AGENT; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TOBRAMYCIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VANCOMYCIN;

EID: 79954994721     PISSN: 13608606     EISSN: None     Source Type: Trade Journal    
DOI: None     Document Type: Review
Times cited : (16)

References (49)
  • 1
    • 0033932274 scopus 로고    scopus 로고
    • Aerosolized antibiotics: Current and future
    • Smaldone GC and Palmer LB. (2000) Aerosolized Antibiotics: Current and Future. Respiratory Care, 45:667-675 (Pubitemid 30484806)
    • (2000) Respiratory Care , vol.45 , Issue.6 , pp. 667-675
    • Smaldone, G.C.1    Palmer, L.B.2
  • 2
    • 0036198938 scopus 로고    scopus 로고
    • The rationale for aerosolized antibiotics
    • Flume P and Klepser ME. (2002) The rationale for aerosolized antibiotics. Pharmacotherapy, 22: S71-S79
    • (2002) Pharmacotherapy , vol.22
    • Flume, P.1    Klepser, M.E.2
  • 3
    • 0031952586 scopus 로고    scopus 로고
    • Pharmacokinetic/pharmacodynamic parameters: Rationale for antibacterial dosing of mice and men
    • Craig WA. (1997) Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men. Clin Infect Dis 26:1-12
    • (1997) Clin Infect Dis , vol.26 , pp. 1-12
    • Craig, W.A.1
  • 4
    • 0027395872 scopus 로고
    • The changing epidemiology of cystic fibrosis
    • Fitzsimmons SC. (1993) The changing epidemiology of cystic fibrosis. J Pediatr 122:1-9
    • (1993) J Pediatr , vol.122 , pp. 1-9
    • Fitzsimmons, S.C.1
  • 5
    • 0033228044 scopus 로고    scopus 로고
    • New approaches to optimizing antimicrobial therapy in patients with cystic fibrosis
    • Beringer PM.(1999) New approaches to optimizing antimicrobial therapy in patients with cystic fibrosis. Curr Opin Pulm Med 5:371-7
    • (1999) Curr Opin Pulm Med , vol.5 , pp. 371-377
    • Beringer, P.M.1
  • 6
    • 0034834836 scopus 로고    scopus 로고
    • Administration of aerosolized antibiotics in cystic fibrosis patients
    • Moss RB. (2001) Administration of aerosolized antibiotics in cystic fibrosis patients. Chest 120:107-113
    • (2001) Chest , vol.120 , pp. 107-113
    • Moss, R.B.1
  • 10
    • 0030999183 scopus 로고    scopus 로고
    • A comparison of peak sputum tobramycin concentration in patients with cystic fibrosis using jet and ultrasonic nebulizer systems
    • Eisenberg J, Pepe M, Williams-Warren J. (1997) A comparison of peak sputum tobramycin concentration in patients with cystic fibrosis using jet and ultrasonic nebulizer systems. Aerosolized tobramycin study group. Chest 111:955-62 (Pubitemid 27171467)
    • (1997) Chest , vol.111 , Issue.4 , pp. 955-962
    • Eisenberg, J.1    Pepe, M.2    Williams-Warren, J.3    Vasiliev, M.4    Bruce, M.A.5    Smith, A.L.6    Ramsey, B.W.7
  • 11
    • 0000920644 scopus 로고    scopus 로고
    • Safety and efficacy of tobramycin solution for inhalation in patients with cystic fibrosis: The results of two phase III placebo controlled clinical trials
    • Ramsey BW, Burns J, Smith A. (1997) Safety and efficacy of tobramycin solution for inhalation in patients with cystic fibrosis: the results of two phase III placebo controlled clinical trials. Pediatr Pulmonol suppl 14:137-8
    • (1997) Pediatr Pulmonol Suppl , vol.14 , pp. 137-138
    • Ramsey, B.W.1    Burns, J.2    Smith, A.3
  • 12
    • 79955014925 scopus 로고    scopus 로고
    • Novartis pharmaceutical Inc. Available from
    • Novartis pharmaceutical Inc. Tobramycin solution for inhalation (2010) Available from: http://www.tobitime.com
    • (2010) Tobramycin Solution for Inhalation
  • 14
    • 84942315255 scopus 로고    scopus 로고
    • Chapter 5: Delivery of Drugs by the Pulmonary Route
    • Applications and Advances Fifth Edition. Taylor & Francis, Inc., New York
    • Hickey A.J. and Mansour H.M. (2009) Chapter 5: Delivery of Drugs by the Pulmonary Route. Modern Pharmaceutics Volume 2: Applications and Advances Fifth Edition. Taylor & Francis, Inc., New York. 191-219
    • (2009) Modern Pharmaceutics , vol.2 , pp. 191-219
    • Hickey, A.J.1    Mansour, H.M.2
  • 15
    • 0032903317 scopus 로고    scopus 로고
    • Preservatives in nebulizer solutions: Risks without benefit - A further comment
    • Beasley R and Hendeles L. (1999) Preservatives in nebulizer solutions: risks without benefit-a further comment. Pharmacotherapy 19:473-4 (Pubitemid 29160165)
    • (1999) Pharmacotherapy , vol.19 , Issue.4 I , pp. 473-474
    • Beasley, R.1    Hendeles, L.2
  • 16
    • 0035113615 scopus 로고    scopus 로고
    • Call for worldwide withdrawal of benzalkonium chloride from nebulizer solutions
    • DOI 10.1067/mai.2001.112941
    • Beasley R, Burgess C, Holt S. (2001) Call for worldwide withdrawal of benzalkonium chloride from nebulizer solutions. J Allergy Clin Immunol 107:222-3 (Pubitemid 32173895)
    • (2001) Journal of Allergy and Clinical Immunology , vol.107 , Issue.2 , pp. 222-223
    • Beasley, R.1    Burgess, C.2    Holt, S.3
  • 17
    • 0032887269 scopus 로고    scopus 로고
    • Bronchoconstrictor additives in bronchodilator solutions
    • Asmus MJ, Sherman J, Hendeles L. (1999) Bronchoconstrictor additives in bronchodilator solutions. J Allergy Clin Immunol 104:553-60
    • (1999) J Allergy Clin Immunol , vol.104 , pp. 553-560
    • Asmus, M.J.1    Sherman, J.2    Hendeles, L.3
  • 18
    • 0029876016 scopus 로고    scopus 로고
    • Inhalation characteristics and their effect on in-vitro drug delivery from dry powder inhalers
    • De Boer AH, Winter HMI, Lerk CF. (1996) Inhalation characteristics and their effect on in-vitro drug delivery from dry powder inhalers. Int J Pharm 130:231-244
    • (1996) Int J Pharm , vol.130 , pp. 231-244
    • De Boer, A.H.1    Winter, H.M.I.2    Lerk, C.F.3
  • 20
    • 0342940773 scopus 로고    scopus 로고
    • In vitro evaluation of dry powder inhalers. I. Drug deposition of commonly used devices
    • Steckel H and Müller BW. (1997) In vitro evaluation of dry powder inhalers. I. Drug deposition of commonly used devices. Int J Pharm 154:19-29
    • (1997) Int J Pharm , vol.154 , pp. 19-29
    • Steckel, H.1    Müller, B.W.2
  • 21
    • 0032416309 scopus 로고    scopus 로고
    • Dry powder inhalers: The influence of device resistance and powder formulation on drug and lactose deposition in vitro
    • DOI 10.1016/S0928-0987(98)00008-6, PII S0928098798000086
    • Srichana T, Martin GP, Mariott C. (1998) Dry powder inhalers: The influence of device resistance and powder formulation on drug and lactose deposition in vitro. Eur J Pharm Sci 7:73-80 (Pubitemid 29056229)
    • (1998) European Journal of Pharmaceutical Sciences , vol.7 , Issue.1 , pp. 73-80
    • Srichana, T.1    Martin, G.P.2    Marriott, C.3
  • 23
    • 77952744763 scopus 로고    scopus 로고
    • Formulation strategy and use of excipients in pulmonary drug delivery
    • Pilcer G and Amighi K. (2010) Formulation strategy and use of excipients in pulmonary drug delivery. Int J Pharm 392:1-19
    • (2010) Int J Pharm , vol.392 , pp. 1-19
    • Pilcer, G.1    Amighi, K.2
  • 26
    • 34247193128 scopus 로고    scopus 로고
    • Novel tobramycin inhalation powder in cystic fibrosis subjects: Pharmacokinetics and safety
    • DOI 10.1002/ppul.20594
    • Geller DE, Konstan MW, Konstan MW, et al. (2007) Novel tobramycin inhalation powder in cystic fibrosis subjects: pharmacokinetics and safety. Pediatr Pulm 42:307-13 (Pubitemid 46608898)
    • (2007) Pediatric Pulmonology , vol.42 , Issue.4 , pp. 307-313
    • Geller, D.E.1    Konstan, M.W.2    Smith, J.3    Moonberg, S.B.4    Conrad, C.5
  • 27
    • 33646896501 scopus 로고    scopus 로고
    • Formulation and characterization of lipid-coated tobramycin particles for dry powder inhalation
    • DOI 10.1007/s11095-006-9789-4
    • Pilcer G, Sebti T, Amighi K. (2006) Formulation and characterization of lipid-coated tobramycin particles for dry powder inhalation. Pharm Res 23:931-40 (Pubitemid 43781401)
    • (2006) Pharmaceutical Research , vol.23 , Issue.5 , pp. 931-940
    • Pilcer, G.1    Sebti, T.2    Amighi, K.3
  • 28
    • 37849042758 scopus 로고    scopus 로고
    • Pharmacoscintigraphic and pharmacokinetic evaluation of tobramycin DPI formulations in cystic fibrosis patients
    • Pilcer G, Goole J, Van Gansbeke B, et al. (2008) Pharmacoscintigraphic and pharmacokinetic evaluation of tobramycin DPI formulations in cystic fibrosis patients. Eur J Pharm Biopharm 68:413-21
    • (2008) Eur J Pharm Biopharm , vol.68 , pp. 413-421
    • Pilcer, G.1    Goole, J.2    Van Gansbeke, B.3
  • 29
    • 63949086375 scopus 로고    scopus 로고
    • Pulmonary spray dried powders of tobramycin containing sodium stearate to improve aerosolization efficiency
    • Parlati C, Buttini F, Ammit AJ, et al. (2009) Pulmonary spray dried powders of tobramycin containing sodium stearate to improve aerosolization efficiency. Pharm Res 26:1084-92
    • (2009) Pharm Res , vol.26 , pp. 1084-1092
    • Parlati, C.1    Buttini, F.2    Ammit, A.J.3
  • 31
    • 70249120202 scopus 로고    scopus 로고
    • Available from
    • Nektar. Anti-Infectives. (2009) Available from: http://www.nektar.com/ product-pipeline/all-phases.html
    • (2009) Anti-Infectives
  • 32
    • 23144466480 scopus 로고    scopus 로고
    • Liposomal Amikacin Dry Powder Inhaler: Effect of Fines on in Vitro Performance
    • Shah SP, Misra A. (2004) Liposomal Amikacin Dry Powder Inhaler: Effect of Fines on In Vitro Performance. AAPS PharmSciTech 5: E65
    • (2004) AAPS PharmSciTech , vol.5
    • Shah, S.P.1    Misra, A.2
  • 33
    • 0028335186 scopus 로고
    • Pulmonary retention of free and liposome-encapsulated tobramycin after intratracheal administration in uninfected rats and rats infected with Pseudomonas aeruginosa
    • Omri A, Beaulac C, Lagacé J, et al. (1994) Pulmonary retention of free and liposome-encapsulated tobramycin after intratracheal administration in uninfected rats and rats infected with Pseudomonas aeruginosa. Antimicrob Agents Chemother 38:1090-5 (Pubitemid 24150843)
    • (1994) Antimicrobial Agents and Chemotherapy , vol.38 , Issue.5 , pp. 1090-1095
    • Omri, A.1    Beaulac, C.2    Bouhajib, M.3    Montplaisir, S.4    Sharkawi, M.5    Lagace, J.6
  • 34
    • 14744306716 scopus 로고    scopus 로고
    • Liposome-mediated gentamicin delivery: Development and activity against resistant strains of Pseudomonas aeruginosa isolated from cystic fibrosis patients
    • DOI 10.1093/jac/dkh518
    • Mugabe C, Azghani AO, Omri A. (2005) Liposomemediated gentamicin delivery: development and activity against resistant strains of Pseudomonas aeruginosa isolated from cystic fibrosis patients. J Antimicrob Chemother 55: 269-71 (Pubitemid 40331158)
    • (2005) Journal of Antimicrobial Chemotherapy , vol.55 , Issue.2 , pp. 269-271
    • Mugabe, C.1    Azghani, A.O.2    Omri, A.3
  • 35
    • 52449086630 scopus 로고    scopus 로고
    • Cospray dried antibiotics for dry powder lung delivery
    • Adi H, Young PM, Chan HK, et al. (2008) Cospray dried antibiotics for dry powder lung delivery. J Pharm Sci 97:3356-66
    • (2008) J Pharm Sci , vol.97 , pp. 3356-3366
    • Adi, H.1    Young, P.M.2    Chan, H.K.3
  • 36
    • 74949121129 scopus 로고    scopus 로고
    • Controlled release antibiotics for dry powder lung delivery
    • Adi H, Young PM, Chan HK, et al. (2010) Controlled release antibiotics for dry powder lung delivery. Drug Dev Ind Pharm 36:119-126
    • (2010) Drug Dev Ind Pharm , vol.36 , pp. 119-126
    • Adi, H.1    Young, P.M.2    Chan, H.K.3
  • 37
    • 53849117442 scopus 로고    scopus 로고
    • Microparticles for inhalational delivery of antipseudomonal antibiotics
    • Tsifansky MD, Yeo Y, Evgenov OV, et al. (2008) Microparticles for inhalational delivery of antipseudomonal antibiotics. AAPS J 10:254-60
    • (2008) AAPS J , vol.10 , pp. 254-260
    • Tsifansky, M.D.1    Yeo, Y.2    Evgenov, O.V.3
  • 38
    • 67349261427 scopus 로고    scopus 로고
    • Preparation of microsized spherical aggregates of ultrafine ciprofloxacin particles for dry powder inhalation (DPI)
    • Zhao H, Liu H, Hu T, et al. (2009) Preparation of microsized spherical aggregates of ultrafine ciprofloxacin particles for dry powder inhalation (DPI). Powder Technol 194:81-6
    • (2009) Powder Technol , vol.194 , pp. 81-86
    • Zhao, H.1    Liu, H.2    Hu, T.3
  • 40
    • 42149119558 scopus 로고    scopus 로고
    • Advanced nebulizer designs employing vibrating mesh/aperture plate technologies for aerosol generation
    • DOI 10.2174/156720108783954815
    • Waldrep JC and Dhand R. (2008) Advanced nebulizer designs employing vibrating mesh/aperture plate technologies for aerosol generation. Curr Drug Deliv 5:114-9 (Pubitemid 351536317)
    • (2008) Current Drug Delivery , vol.5 , Issue.2 , pp. 114-119
    • Waldrep, J.C.1    Dhand, R.2
  • 41
    • 16344381319 scopus 로고    scopus 로고
    • Antiinflammatory therapies for cystic fibrosis: Past, present, and future
    • Prescott WA and Johnson CE. (2005) Antiinflammatory therapies for cystic fibrosis: past, present, and future. Pharmacotherapy 25:555-73
    • (2005) Pharmacotherapy , vol.25 , pp. 555-573
    • Prescott, W.A.1    Johnson, C.E.2
  • 43
    • 54549115069 scopus 로고    scopus 로고
    • Formulation, characteristics and aerosolization performance of azithromycin DPI prepared by spray-drying
    • Zhao M, Yao Y, Ren Y, et al. (2008) Formulation, characteristics and aerosolization performance of azithromycin DPI prepared by spray-drying. Powder Technol 187:214-21
    • (2008) Powder Technol , vol.187 , pp. 214-221
    • Zhao, M.1    Yao, Y.2    Ren, Y.3
  • 44
    • 0035985874 scopus 로고    scopus 로고
    • Dry powder inhalation of antibiotics in cystic fibrosis therapy, part 1: Development of a powder formulation with colistin sulfate for a special test inhaler with an air classifier as de-agglomeration principle
    • DOI 10.1016/S0939-6411(02)00043-7, PII S0939641102000437
    • De Boer AH, Le Brun PPH, van der Woude HG, et al. (2002) Dry powder inhalation of antibiotics in cystic fibrosis therapy, part 1: development of a powder formulation with colistin sulfate for a special test inhaler with an air classifier as de-agglomeration principle. Eur J Pharm Biopharm 54:17-24 (Pubitemid 34663852)
    • (2002) European Journal of Pharmaceutics and Biopharmaceutics , vol.54 , Issue.1 , pp. 17-24
    • De Boer, A.H.1    Le, B.P.P.H.2    Van Der, W.H.G.3    Hagedoorn, P.4    Heijerman, H.G.M.5    Frijlink, H.W.6
  • 46
    • 79954993632 scopus 로고    scopus 로고
    • available from
    • Search for clinical trials. 2010. available from: http://www. clinicaltrial.gov/ct2/search
    • (2010) Search for Clinical Trials
  • 47
    • 64749110689 scopus 로고    scopus 로고
    • Recent advances in liposomal dry powder formulations: Preparation and evaluation
    • Misra A, Jinturkar K, Patel D, et al. (2009) Recent advances in liposomal dry powder formulations: preparation and evaluation. Expert Opin Drug Deliv 6:71-89
    • (2009) Expert Opin Drug Deliv , vol.6 , pp. 71-89
    • Misra, A.1    Jinturkar, K.2    Patel, D.3
  • 48
    • 70249104706 scopus 로고    scopus 로고
    • Delivery of antibiotics to the respiratory tract: An update
    • Traini D and Young PM. (2009) Delivery of antibiotics to the respiratory tract: an update. Expert Opin Drug Deliv 6: 897-905
    • (2009) Expert Opin Drug Deliv , vol.6 , pp. 897-905
    • Traini, D.1    Young, P.M.2
  • 49
    • 0034828531 scopus 로고    scopus 로고
    • Formulation of aerosolized therapeutics
    • Kuhn RJ. (2001) Formulation of aerosolized therapeutics. Chest 120:94S-98S
    • (2001) Chest , vol.120
    • Kuhn, R.J.1


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