Methods for quantitative evaluation of alveolar structure during in vivo microscopy

Respiratory Physiology and Neurobiology

Volumn 176, Issue 3, 2011, Pages 123-129

  Czaplik, M ^a   Rossaint, R ^a   Koch, E ^b   Fahlenkamp, A ^a   Schroder W ^c   Pelosi, P ^d   Kubler W M ^e   Bickenbach, J ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^c RWTH AACHEN UNIVERSITY   (Germany)

^d UNIVERSITY OF GENOA   (Italy)

^e CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Acute lung injury; Acute respiratory distress syndrome; Fibred confocal laser scanning microscopy; Lung; Quantification algorithm

Indexed keywords

ACUTE LUNG INJURY; ALGORITHM; ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CIRCULARITY INDEX; EXPERIMENTAL PIG; FEMALE; HETEROGENEITY INDEX; IN VIVO STUDY; LUNG ALVEOLUS; MALE; MICROSCOPE IMAGE; MICROSCOPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; VOLUME AIR INDEX;

ACUTE LUNG INJURY; ANIMALS; FEMALE; MICE; MICE, INBRED BALB C; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; PULMONARY ALVEOLI; SWINE;

EID: 79954976061     PISSN: 15699048     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.resp.2011.02.009     Document Type: Article

References (20)

1. Amato M.B., Barbas C.S., Medeiros D.M., Magaldi R.B., Schettino G.P., Lorenzi-Filho G., Kairalla R.A., Deheinzelin D., Munoz C., Oliveira R., Takagaki T.Y., Carvalho C.R. Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome. N. Engl. J. Med. 1998, 338:347-354.
2. Bickenbach J., Czaplik M., Dembinski R., Pelosi P., Schroeder W., Marx G., Rossaint R. In vivo microscopy in a porcine model of acute lung injury. Respir. Physiol. Neurobiol. 2010, 172(3):192-200.
3. Bickenbach J., Zoremba N., Fries M., Dembinski R., Doering R., Ogawa E., Rossaint R., Kuhlen R. Low tidal volume ventilation in a porcine model of acute lung injury improves cerebral tissue oxygenation. Anesth. Analg. 2009, 109(3):847-855.
4. Bickenbach J., Dembinski R., Czaplik M., Meissner S., Tabuchi A., Mertens M., Knels L., Schroeder W., Pelosi P., Koch E., Kuebler W., Rossaint R., Kuhlen R. Comparison of two in vivo microscopy techniques to visualize alveolar mechanics. J. Clin. Monit. Comput. 2009, 23(5):323-332.
5. Brochard L., Roudot-Thoraval F., Roupie E., Delclaux C., Chastre J., Fernandez-Mondéjar E., Clémenti E., Mancebo J., Factor P., Matamis D., Ranieri M., Blanch L., Rodi G., Mentec H., Dreyfuss D., Ferrer M., Brun-Buisson C., Tobin M., Lemaire F. Tidal volume reduction for prevention of ventilator-induced lung injury in acute respiratory distress syndrome. Am. J. Respir. Crit. Care Med. 1998, 158:1831-1838.
6. Carney D.E., Bredenberg C.E., Schiller H.J., Picone A.L., McCann U.G., Gatto L.A., Bailey G., Fillinger M., Nieman G.F. The mechanism of lung volume change during mechanical ventilation. Am. J. Respir. Crit. Care Med. 1999, 160:1697-1702.
7. Henzler D., Pelosi P., Bensberg R., Dembinski R., Quintel M., Pielen V., Rossaint R., Kuhlen R Effects of partial ventilatory support modalities on respiratory function in severe hypoxemic lung injury. Crit. Care Med. 2006, 34(6):1738-1745.
8. Heywood H. Particle shape coefficients. J. Imperial Coll. Chem. Soc. 1954, 8:15-33.
9. Lachmann B., Robertson B., Vogel J. In vivo lung lavage as an experimental model of the respiratory distress syndrome. Acta Anaesthesiol. Scand. 1980, 24:231-236.
10. McCann U.G., Schiller H.J., Carney D.E., Gatto L.A., Steinberg J.M., Nieman G.F. Visual validation of the mechanical stabilizing effects of positive end-expiratory pressure at the alveolar level. J. Surg. Res. 2001, 99(2):335-342.
11. Mertens M., Tabuchi A., Meissner S., Krueger A., Schirrmann K., Kertzscher U., Pries A.R., Slutsky A.S., Koch E., Kuebler W.M. Alveolar dynamics in acute lung injury: heterogeneous distension rather than cyclic opening and collapse. Crit. Care Med. 2009, 37(9):2604-2611.
12. Namati E., Thiesse J., de Ryk J., McLennan G. Alveolar dynamics during respiration: are the pores of Kohn a pathway to recruitment?. Am. J. Respir. Cell Mol. Biol. 2008, 38(5):572-578.
13. Niblack W. An Introduction to Digital Image Processing 1986, Prentice Hall, Englewood Cliffs, N.J., pp. 115-116.
14. Pavone L.A., Albert S., Carney D., Gatto L.A., Halter J.M., Nieman G.F. Injurious mechanical ventilation in the normal lung causes a progressive pathologic change in dynamic alveolar mechanics. Crit. Care 2007, 11(3):R64.
15. Putensen C., Theuerkauf N., Zinserling J., Wrigge H., Pelosi P. Meta-analysis: ventilation strategies and outcomes of the acute respiratory distress syndrome and acute lung injury. Ann. Intern. Med. 2009, 151(8):566-576.
16. Schiller H.J., Steinberg J., Halter J., McCann U., DaSilva M., Gatto L.A., Carney D., Nieman G. Alveolar inflation during generation of a quasi-static pressure/volume curve in the acutely injured lung. Crit. Care Med. 2003, 31(4):1126-1133.
17. Schiller H.J., McCann U.G., Carney D.E., Gatto L.A., Steinberg J.M., Nieman G.F. Altered alveolar mechanics in the acutely injured lung. Crit. Care Med. 2001, 29(5):1049-1055.
18. Steinberg J., Schiller H.J., Halter J.M., Gatto L.A., Dasilva M., Amato M., McCann U.G., Nieman G.F. Tidal volume increases do not affect alveolar mechanics in normal lung but cause alveolar overdistension and exacerbate alveolar instability after surfactant deactivation. Crit. Care Med. 2002, 30(12):2675-2683.
19. The Acute Respiratory Distress Syndrome Network Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N. Engl. J. Med. 2000, 342:1301-1308.
20. Thiberville L., Salaün M., Lachkar S., Dominique S., Moreno-Swirc S., Vever-Bizet C., Bourg-Heckly G. Human in vivo fluorescence microimaging of the alveolar ducts and sacs during bronchoscopy. Eur. Respir. J. 2009, 33(5):974-985.