Cyclin E1 is amplified and overexpressed in osteosarcoma

Journal of Molecular Diagnostics

Volumn 13, Issue 3, 2011, Pages 289-296

  Lockwood, William W ^a   Stack, Deirdre ^b   Morris, Thomas ^c   Grehan, David ^d   O'Keane, Conor ^f   Stewart, Greg L ^a   Cumiskey, Joanna ^f   Lam, Wan L ^a   Squire, Jeremy A ^g   Thomas, David M ^e   O'Sullivan, Maureen J ^h  

^a BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

^b National Children's Research Center   (Canada)

^c National Center for Medical Genetics   (Canada)

^d Histology Laboratory Pathology Department   (Canada)

^e OUR LADY S CHILDREN S HOSPITAL   (Ireland)

^f MATER MISERICORDIAE UNIVERSITY HOSPITAL   (Ireland)

^g KINGSTON GENERAL HOSPITAL   (Canada)

^h Cancer Center   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN E; CYCLIN E1; UNCLASSIFIED DRUG;

ARTICLE; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; COPY NUMBER VARIATION; CORRELATION ANALYSIS; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE OVEREXPRESSION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; OSTEOSARCOMA; PROGNOSIS;

EID: 79954965424     PISSN: 15251578     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmoldx.2010.11.020     Document Type: Article

References (33)

1. Kansara M, Thomas DM: Molecular pathogenesis of osteosarcoma. DNA Cell Biol 2007, 26:1-18 (Pubitemid 46219587)
2. Hansen MF: Genetic and molecular aspects of osteosarcoma. J Musculoskelet Neuronal Interact 2002, 2:554-560 (Pubitemid 36157602)
3. Meyers PA, Heller G, Healey JH, Huvos A, Applewhite A, Sun M, LaQuaglia M: Osteogenic sarcoma with clinically detectable metastasis at initial presentation. J Clin Oncol 1993, 11:449-453 (Pubitemid 23071040)
4. Meyers PA, Gorlick R: Osteosarcoma. Pediatr Clin North Am 1997, 44:973-989 (Pubitemid 27368674)
5. Greene LF: AJCC Cancer Staging Manual. New York, Springer-Verlag, 2002
6. Lamoureux F, Trichet V, Chipoy C, Blanchard F, Gouin F, Redini F: Recent advances in the management of osteosarcoma and forthcoming therapeutic strategies. Expert Rev Anticancer Ther 2007, 7:169-181 (Pubitemid 46277282)
7. Lau CC, Harris CP, Lu XY, Perlaky L, Gogineni S, Chintagumpala M, Hicks J, Johnson ME, Davino NA, Huvos AG, Meyers PA, Healy JH, Gorlick R, Rao PH: Frequent amplification and rearrangement of chromosomal bands 6p12-p21 and 17p11.2 in osteosarcoma. Genes Chromosomes Cancer 2004, 39:11-21 (Pubitemid 37475248)
8. Sandberg AA, Bridge JA. Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: osteosarcoma and related tumors. Cancer Genet Cytogenet 2003, 145:1-30 (Pubitemid 36926284)
9. Zielenska M, Bayani J, Pandita A, Toledo S, Marrano P, Andrade J, Petrilli A, Thorner P, Sorenson P, Squire JA: Comparative genomic hybridization analysis identifies gains of 1p35 approximately p36 and chromosome 19 in osteosarcoma. Cancer Genet Cytogenet 2001, 130:14-21 (Pubitemid 32979161)
10. Rosen G, Caparros B, Huvos AG, Kosloff C, Nirenberg A, Cacavio A, Marcove RC, Lane JM, Mehta B, Urban C: Preoperative chemotherapy for osteogenic sarcoma: selection of postoperative adjuvant chemotherapy based on the response of the primary tumor to preoperative chemotherapy. Cancer 1982, 49:1221-1230 (Pubitemid 12187826)
11. Lockwood WW, Chari R, Coe BP, Girard L, Macaulay C, Lam S, Gazdar AF, Minna JD, Lam WL: DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers. Oncogene 2008, 27:4615-4624
12. Khojasteh M, Lam WL, Ward RK, MacAulay C: A stepwise framework for the normalization of array CGH data. BMC Bioinformatics 2005, 6:274
13. Chi B, deLeeuw RJ, Coe BP, Ng RT, MacAulay C, Lam WL: MDSeeGH: a platform for integrative analysis of multi-dimensional genomic data. BMC Bioinformatics 2008, 9:243
14. Jong K, Marchiori E, Meijer G, Vaart AV, Ylstra B: Breakpoint identification and smoothing of array comparative genomic hybridization data. Bioinformatics 2004, 20:3636-3637 (Pubitemid 40136800)
15. Beroukhim R, Getz G, Nghiemphu L, Barretina J, Hsueh T, Linhart D, Vivanco I, Lee JC, Huang JH, Alexander S, Du J, Kau T, Thomas RK, Shah K, Soto H, Perner S, Prensner J, Debiasi RM, Demichelis F, Hatton C, Rubin MA, Garraway LA, Nelson SF, Liau L, Mischel PS, Cloughesy TF, Meyerson M, Golub TA, Lander ES, Mellinghoff IK, Sellers WR: Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma. Proc Natl Acad Sci U S A 2007, 104:20007-20012
16. Wong KK, deLeeuw RJ, Dosanjh NS, Kimm LR, Cheng Z, Horsman DE, MacAulay C, Ng RT, Brown CJ, Eichler EE, Lam WL: A comprehensive analysis of common copy-number variations in the human genome. Am J Hum Genet 2007, 80:91-104 (Pubitemid 46047653)
17. Whiteford CC, Bilke S, Greer BT, Chen Q, Braunschweig TA, Cenacchi N, Wei JS, Smith MA, Houghton P, Morton C, Reynolds CP, Lock R, Gorlick R, Khanna C, Thiele CJ, Takikita M, Catchpoole D, Hewitt SM, Khan J: Credentialing preclinical pediatric xenograft models using gene expression and tissue microarray analysis. Cancer Res 2007, 67:32-40 (Pubitemid 46142757)
18. Sturn A, Quackenbush J, Trajanoski Z: Genesis: cluster analysis of microarray data. Bioinformatics 2002, 18:207-208 (Pubitemid 34145055)
19. Mintz MB, Sowers R, Brown KM, Hilmer SC, Mazza B, Huvos AG, Meyers PA, Lafleur B, McDonough WS, Henry MM, Ramsey KE, Antonescu CR, Chen W, Healey JH, Daluski A, Berens ME, Macdonald TJ, Gorlick R, Stephan DA: An expression signature classifies chemotherapy-resistant pediatric osteosarcoma. Cancer Res 2005, 65:1748-1754 (Pubitemid 40478600)
20. Kansara M, Tsang M, Kodjabachian L, Sims NA, Trivett MK, Ehrich M, Dobrovic A, Slavin J, Choong PFM, Simmons PJ, Dawid IB, Thomas DM: Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice. J Clin Invest 2009, 119:837-851
21. Irizarry RA, Hobbs B, Collin F, Beazer-Barclay YD, Antonellis KJ, Scherf U, Speed TP: Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 2003, 4:249-264
22. Morrison LE, Legator MS: Multicolour FISH techniques. Introduction to Fluorescence In Situ Hybridization: Principles and Clinical Applications. Edited by M Andreeff, D Pinkel. New York, Wiley-Liss Inc, 1999, pp 3-12
23. Herrera RE, Sah VP, Williams BO, Makela TP, Weinberg RA, Jacks T: Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts. Mol Cell Biol 1996, 16:2402-2407 (Pubitemid 26123762)
24. 130 are required for the regulated expression of different sets of E2F responsive genes. Genes Dev 1997, 11:1447-1463 (Pubitemid 27259855)
25. Geng Y, Yu Q, Sicinska E, Das M, Schneider JE, Bhattacharya S, Rideout WM, Bronson RT, Gardner H, Sicinski P: Cyclin E ablation in the mouse. Cell 2003, 114:431-443 (Pubitemid 37100992)
26. Xiao ZX, Ginsberg D, Ewen M, Livingston DM: Regulation of the retinoblastoma protein-related protein p107 by G1 cyclin-associated kinases. Proc Natl Acad Sci U S A 1996, 93:4633-4637 (Pubitemid 26163494)
27. Li Y, Graham C, Lacy S, Duncan AMV, Whyte P: The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E. Genes Dev 1993, 7:2366-2377 (Pubitemid 24003240)
28. Zhang H: Life without kinase: cyclin E promotes DNA replication licensing and beyond. Mol Cell 2007, 175-176 (Pubitemid 46109616)
29. Geng Y, Lee YM, Welcker M, Swanger J, Zagozdzon A, Winer JD, Roberts JM, Kaldis P, Clurman BE, Sicinski P: Kinase-independent function of cyclin E. Mol Cell 2007, 25:127-139 (Pubitemid 46049064)
30. Caldon CE, Musgrove EA: Distinct and redundant functions of cyclin E1 and cyclin E2 in development and cancer. Cell Div 2010, 5:2
31. Spruck CH, Won KA, Reed SI: Deregulated cyclin E induces chromosome instability. Nature 1999, 401:297-300
32. Moroy T, Geisen C: Cyclin E. Int J Biochem Cell Biol 2004, 36:1424-1439
33. Etemadmoghadam D, deFazio A, Beroukhim R, Mermel C, George J, Getz G, Tothill R, Okamoto A, Raeder MB, Harnett P, Lade S, Akslen LA, Tinker AV, Locandro B, Alsop K, Chiew YE, Traficante N, Fereday S, Johnson D, Fox S, Sellers W, Urashima M, Salvesen HB, Meyerson M, Bowtell D: Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas. Clin Cancer Res 2009, 15:1417-1427