메뉴 건너뛰기




Volumn 90, Issue 3, 2011, Pages 929-939

Comparative analysis of tertiary alcohol esterase activity in bacterial strains isolated from enrichment cultures and from screening strain libraries

Author keywords

Biotransformation; Enrichment; Esterase; Screening; Tertiary alcohol

Indexed keywords

ALCALIGENES SP; BACTERIAL STRAINS; BELONG TO; BIOTRANSFORMATION; BUILDING BLOCKES; COMPARATIVE ANALYSIS; ENANTIOPURE; ENANTIOSELECTIVE HYDROLYSIS; ENRICHMENT; ENRICHMENT CULTURE; ESTERASE; ESTERASE ACTIVITIES; FUNCTIONAL SCREENING; HYDROLYTIC ACTIVITIES; MICROBACTERIUM; ORGANIC SYNTHESIS; PHARMACEUTICAL COMPOUNDS; RHODOCOCCUS RUBER; SOLE SOURCE OF CARBON; TERT-BUTYL ACETATES; TERTIARY ALCOHOL; TERTIARY ALCOHOLS; WALL TYPES;

EID: 79954956681     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-011-3124-7     Document Type: Article
Times cited : (11)

References (41)
  • 1
    • 77952145686 scopus 로고    scopus 로고
    • Synthesis of (+)- and (-)-gossonorol and cyclisation to boivinianin B
    • 10.1002/ejoc.201000391
    • K Abecassis SE Gibson 2010 Synthesis of (+)- and (-)-gossonorol and cyclisation to boivinianin B Eur J Org Chem 15 2938 2944 10.1002/ejoc.201000391
    • (2010) Eur J Org Chem , vol.15 , pp. 2938-2944
    • Abecassis, K.1    Gibson, S.E.2
  • 2
    • 0019402999 scopus 로고
    • Synthesis of 3-aryl-3-pyridylallylamines related to zimelidine via palladium-catalyzed amination
    • DOI 10.1021/jo00330a019
    • J Baeckvall R Nordberg J Nystroem 1981 Synthesis of 3-aryl-3- pyridylallylamines related to zimelidine via palladium-catalyzed amination J Org Chem 46 3479 3483 10.1021/jo00330a019 1:CAS:528:DyaL3MXkvVSltLc%3D (Pubitemid 11028818)
    • (1981) Journal of Organic Chemistry , vol.46 , Issue.17 , pp. 3479-3483
    • Backvall, J.E.1    Nordberg, R.E.2    Nystrom, J.E.3
  • 3
    • 0032747877 scopus 로고    scopus 로고
    • Identification and environmental detection of Rhodococcus species by 16S rDNA-targeted PCR
    • 10.1046/j.1365-2672.1999.00824.x 1:CAS:528:DyaK1MXotFWkt7c%3D
    • KS Bell MS Kuyukina S Heidbrink JC Philp DWJ Aw IB Ivshina N Christofi 1999 Identification and environmental detection of Rhodococcus species by 16S rDNA-targeted PCR J Appl Microbiol 87 472 480 10.1046/j.1365-2672.1999.00824.x 1:CAS:528:DyaK1MXotFWkt7c%3D
    • (1999) J Appl Microbiol , vol.87 , pp. 472-480
    • Bell, K.S.1    Kuyukina, M.S.2    Heidbrink, S.3    Philp, J.C.4    Aw, D.W.J.5    Ivshina, I.B.6    Christofi, N.7
  • 4
    • 0034097143 scopus 로고    scopus 로고
    • Gene cloning and nucleotide sequencing and properties of a cocaine esterase from Rhodococcus sp. strain MB1
    • DOI 10.1128/AEM.66.3.904-908.2000
    • MM Bresler SJ Rosser A Basran NC Bruce 2000 Gene cloning and nucleotide sequencing and properties of a cocaine esterase from Rhodococcus sp. strain MB1 Appl Environ Microbiol 66 904 908 10.1128/AEM.66.3.904-908.2000 1:CAS:528:DC%2BD3cXhsFyrtr4%3D (Pubitemid 30130004)
    • (2000) Applied and Environmental Microbiology , vol.66 , Issue.3 , pp. 904-908
    • Bresler, M.M.1    Rosser, S.J.2    Basran, A.3    Bruce, N.C.4
  • 5
    • 0042249348 scopus 로고    scopus 로고
    • Metal-catalyzed enantioselective α-ketol rearrangements
    • Brunner H, Stohr F (2000) Metal-catalyzed enantioselective α-ketol rearrangements. Eur J Org Chem, 2777-2786
    • (2000) Eur J Org Chem , pp. 2777-2786
    • Brunner, H.1    Stohr, F.2
  • 7
    • 0042736277 scopus 로고    scopus 로고
    • Metabolism of butyl benzyl phthalate by Gordonia sp. strain MTCC 4818
    • DOI 10.1016/S0006-291X(03)01513-4
    • S Chatterjee TK Dutta 2003 Metabolism of butyl benzyl phthalate by Gordonia sp. strain MTCC 4818 Biochem Biophys Res Commun 309 36 43 10.1016/S0006-291X(03)01513-4 1:CAS:528:DC%2BD3sXmslehurs%3D (Pubitemid 36999755)
    • (2003) Biochemical and Biophysical Research Communications , vol.309 , Issue.1 , pp. 36-43
    • Chatterjee, S.1    Dutta, T.K.2
  • 8
    • 20644469267 scopus 로고
    • Quantitative analyses of biochemical kinetic resolutions of enantiomers
    • 10.1021/ja00389a064 1:CAS:528:DyaL3sXitlGm
    • C Chen Y Fujimoto G Girdaukas C Sih 1982 Quantitative analyses of biochemical kinetic resolutions of enantiomers J Am Chem Soc 104 7294 7299 10.1021/ja00389a064 1:CAS:528:DyaL3sXitlGm
    • (1982) J Am Chem Soc , vol.104 , pp. 7294-7299
    • Chen, C.1    Fujimoto, Y.2    Girdaukas, G.3    Sih, C.4
  • 9
    • 37549063959 scopus 로고    scopus 로고
    • Enantioselective catalytic formation of quaternary stereogenic centers
    • Cozzi P, Hilgraf R, Zimmermann N (2007) Enantioselective catalytic formation of quaternary stereogenic centers. Eur J Org Chem, 5969-5994
    • (2007) Eur J Org Chem , pp. 5969-5994
    • Cozzi, P.1    Hilgraf, R.2    Zimmermann, N.3
  • 12
    • 0031942531 scopus 로고    scopus 로고
    • Isolation of two aerobic bacterial strains that degrade efficiently ethyl t-butyl ether (ETBE)
    • DOI 10.1023/A:1005390221856
    • F Fayolle G Hernandez F Le Roux J-P Vandecasteele 1998 Isolation of two aerobic bacterial strains that degrade efficiently ethyl t-butyl ether (ETBE) Biotechnol Lett 20 283 286 10.1023/A:1005390221856 1:CAS:528:DyaK1cXit1entL8%3D (Pubitemid 28135022)
    • (1998) Biotechnology Letters , vol.20 , Issue.3 , pp. 283-286
    • Fayolle, F.1    Hernandez, G.2    Le Roux, F.3    Vandecasteele, J.-P.4
  • 13
    • 0000140586 scopus 로고    scopus 로고
    • Cyanohydrins in Nature and the Laboratory: Biology, Preparations, and Synthetic Applications
    • R Gregory 1999 Cyanohydrins in nature and the laboratory: biology, preparations, and synthetic applications Chem Rev 12 3649 3682 10.1021/cr9902906 (Pubitemid 129589131)
    • (1999) Chemical Reviews , vol.99 , Issue.12 , pp. 3649-3682
    • Gregory, R.J.H.1
  • 14
    • 0030793539 scopus 로고    scopus 로고
    • Metabolism of diethyl ether and cometabolism of methyl tert-butyl ether by a filamentous fungus, a Graphium sp.
    • L Hardison S Curry L Ciuffetti M Hyman 1997 Metabolism of diethyl ether and cometabolism of methyl tert-butyl ether by a filamentous fungus, a Graphium sp Appl Environ Microbiol 63 3059 3067 1:CAS:528:DyaK2sXlt1Wju70%3D (Pubitemid 27337794)
    • (1997) Applied and Environmental Microbiology , vol.63 , Issue.8 , pp. 3059-3067
    • Hardison, L.K.1    Curry, S.S.2    Ciuffetti, L.M.3    Hyman, M.R.4
  • 15
    • 0026696672 scopus 로고
    • Conversion of cis unsaturated fatty acids to trans, a possible mechanism for the protection of phenol-degrading Pseudomonas putida P8 from substrate toxicity
    • 1:CAS:528:DyaK38XksVCgsro%3D
    • HJ Heipieper R Diefenbach H Keweloh 1992 Conversion of cis unsaturated fatty acids to trans, a possible mechanism for the protection of phenol-degrading Pseudomonas putida P8 from substrate toxicity Appl Environ Microbiol 58 1847 1852 1:CAS:528:DyaK38XksVCgsro%3D
    • (1992) Appl Environ Microbiol , vol.58 , pp. 1847-1852
    • Heipieper, H.J.1    Diefenbach, R.2    Keweloh, H.3
  • 16
    • 0037008979 scopus 로고    scopus 로고
    • Activity of lipases and esterases towards tertiary alcohols: Insights into structure-function relationships
    • DOI 10.1002/1521-3773(20020902)41:17<3211::AID-ANIE3211>3.0.CO;2-U
    • E Henke J Pleiss U Bornscheuer 2002 Activity of lipases and esterases towards tertiary alcohols: Insights into structure-function relationships Angew Chem Int Ed 41 3211 3213 10.1002/1521-3773(20020902)41:17<3211::AID- ANIE3211>3.0.CO;2-U 1:CAS:528:DC%2BD38XntFWku7s%3D (Pubitemid 35014389)
    • (2002) Angewandte Chemie - International Edition , vol.41 , Issue.17 , pp. 3211-3213
    • Henke, E.1    Pleiss, J.2    Bornscheuer, U.T.3
  • 17
    • 0035106489 scopus 로고    scopus 로고
    • Biodegradation of ethyl t-butyl ether (ETBE), methyl t-butyl ether (MTBE) and t-amyl methyl ether (TAME) by Gordonia terrae
    • DOI 10.1007/s002530000482
    • G Hernandez-Perez F Fayolle JP Vandecasteele 2001 Biodegradation of ethyl t-butyl ether (E TBE), methyl t-butyl ether (MTBE) and t-amyl methyl ether (TAME) by Gordonia terrae Appl Microbiol Biotechnol 55 117 121 10.1007/s002530000482 1:CAS:528:DC%2BD3MXht1Glt70%3D (Pubitemid 32206382)
    • (2001) Applied Microbiology and Biotechnology , vol.55 , Issue.1 , pp. 117-121
    • Hernandez-Perez, G.1    Fayolle, F.2    Vandecasteele, J.-P.3
  • 19
    • 0032053411 scopus 로고    scopus 로고
    • Effect of selected environmental factors on degradation and mineralization of biaryl compounds by the bacterium Ralstonia pickettii in soil and compost
    • DOI 10.1016/S0045-6535(97)10201-6, PII S0045653597102016
    • K Hundt M Wagner D Becher E Hammer F Schauer 1998 Effect of selected environmental factors on degradation and mineralization of biaryl compounds by the bacterium Ralstonia pickettii in soil and compost Chemosphere 36 2321 2335 10.1016/S0045-6535(97)10201-6 1:CAS:528:DyaK1cXitFaksbY%3D (Pubitemid 28142445)
    • (1998) Chemosphere , vol.36 , Issue.10 , pp. 2321-2335
    • Hundt, K.1    Wagner, M.2    Becher, D.3    Hammer, E.4    Schauer, F.5
  • 20
    • 79954762365 scopus 로고    scopus 로고
    • Prediction of the Candida antarctica lipase A protein structure by comparative modeling and site-directed mutagenesis
    • 10.1002/cbic.200890063 1:CAS:528:DC%2BD1cXhsVCjsbnJ
    • A Kasrayan M Bocola AG Sandström G Lavén J-E Bäckvall 2008 Prediction of the Candida antarctica lipase A protein structure by comparative modeling and site-directed mutagenesis Chembiochem 9 2559 2559 10.1002/cbic.200890063 1:CAS:528:DC%2BD1cXhsVCjsbnJ
    • (2008) Chembiochem , vol.9 , pp. 2559-2559
    • Kasrayan, A.1    Bocola, M.2    Sandström, A.G.3    Lavén, G.4    Bäckvall, J.-E.5
  • 21
    • 0008560896 scopus 로고
    • Studies on metabolism of amides in Mycobacteriaceae. 4. Formation and hydrolysis of hydroxamate
    • 1:CAS:528:DyaF3cXltV2gtA%3D%3D
    • T Kimura 1959 Studies on metabolism of amides in Mycobacteriaceae. 4. Formation and hydrolysis of hydroxamate J Biochem (Tokyo) 46 1399 1410 1:CAS:528:DyaF3cXltV2gtA%3D%3D
    • (1959) J Biochem (Tokyo) , vol.46 , pp. 1399-1410
    • Kimura, T.1
  • 22
    • 40949160217 scopus 로고    scopus 로고
    • Enzymatic synthesis of optically active tertiary alcohols: Expanding the biocatalysis toolbox
    • 10.1002/cbic.200700688 1:CAS:528:DC%2BD1cXlt1Wht70%3D
    • R Kourist P de Maria U Bornscheuer 2008 Enzymatic synthesis of optically active tertiary alcohols: expanding the biocatalysis toolbox Chembiochem 9 491 498 10.1002/cbic.200700688 1:CAS:528:DC%2BD1cXlt1Wht70%3D
    • (2008) Chembiochem , vol.9 , pp. 491-498
    • Kourist, R.1    De Maria, P.2    Bornscheuer, U.3
  • 23
    • 49049112815 scopus 로고    scopus 로고
    • Hydrolase-catalyzed stereoselective preparation of protected α, α-dialkyl-α-hydroxycarboxylic acids
    • 10.1016/j.tetasy.2008.07.005 1:CAS:528:DC%2BD1cXhtVWksrbO
    • R Kourist G Nguyen D Strübing D Böttcher K Liebeton C Naumer J Eck U Bornscheuer 2008 Hydrolase-catalyzed stereoselective preparation of protected α, α-dialkyl-α-hydroxycarboxylic acids Tetrahedron Asymmetr 19 1839 1843 10.1016/j.tetasy.2008.07.005 1:CAS:528:DC%2BD1cXhtVWksrbO
    • (2008) Tetrahedron Asymmetr , vol.19 , pp. 1839-1843
    • Kourist, R.1    Nguyen, G.2    Strübing, D.3    Böttcher, D.4    Liebeton, K.5    Naumer, C.6    Eck, J.7    Bornscheuer, U.8
  • 24
    • 20444371027 scopus 로고    scopus 로고
    • Biodegradation and Rhodococcus - Masters of catabolic versatility
    • DOI 10.1016/j.copbio.2005.04.007, PII S0958166905000637
    • MJ Larkin LA Kulakov CCR Allen 2005 Biodegradation and Rhodococcus-masters of catabolic versatility Curr Opin Biotechnol 16 282 290 10.1016/j.copbio.2005.04.007 1:CAS:528:DC%2BD2MXlt1Wis74%3D (Pubitemid 40806465)
    • (2005) Current Opinion in Biotechnology , vol.16 , Issue.3 SPEC. ISS. , pp. 282-290
    • Larkin, M.J.1    Kulakov, L.A.2    Allen, C.C.R.3
  • 26
    • 77949392027 scopus 로고    scopus 로고
    • Characteristics and function of Alcaligenes sp. NBRC 14130 esterase catalysing the stereo-selective hydrolysis of ethyl chrysanthemate
    • 10.1111/j.1365-2672.2009.04522.x 1:CAS:528:DC%2BC3cXlt1Oqtr4%3D
    • K Mitsukura M Shimizu K Matsushita T Yoshida T Nagasawa 2010 Characteristics and function of Alcaligenes sp. NBRC 14130 esterase catalysing the stereo-selective hydrolysis of ethyl chrysanthemate J Appl Microbiol 108 1263 1270 10.1111/j.1365-2672.2009.04522.x 1:CAS:528:DC%2BC3cXlt1Oqtr4%3D
    • (2010) J Appl Microbiol , vol.108 , pp. 1263-1270
    • Mitsukura, K.1    Shimizu, M.2    Matsushita, K.3    Yoshida, T.4    Nagasawa, T.5
  • 28
    • 77954250353 scopus 로고    scopus 로고
    • Oxidation of aliphatic, branched chain, and aromatic hydrocarbons by Nocardia cyriacigeorgica isolated from oil-polluted sand samples collected in the Saudi Arabian Desert
    • 10.1002/jobm.200900358 1:CAS:528:DC%2BC3cXhtVehtL3J
    • LT Nhi-Cong A Mikolasch H Sheikhany H Klenk F Schauer 2010 Oxidation of aliphatic, branched chain, and aromatic hydrocarbons by Nocardia cyriacigeorgica isolated from oil-polluted sand samples collected in the Saudi Arabian Desert J Basic Microbiol 50 241 253 10.1002/jobm.200900358 1:CAS:528:DC%2BC3cXhtVehtL3J
    • (2010) J Basic Microbiol , vol.50 , pp. 241-253
    • Nhi-Cong, L.T.1    Mikolasch, A.2    Sheikhany, H.3    Klenk, H.4    Schauer, F.5
  • 29
    • 33646089445 scopus 로고    scopus 로고
    • A mono-2-ethylhexyl phthalate hydrolase from a Gordonia sp. that is able to dissimilate di-2-ethylhexyl phthalate
    • 10.1128/AEM.72.4.2394-2399.2006 1:CAS:528:DC%2BD28XktFagtL8%3D
    • T Nishioka M Iwata T Imaoka M Mutoh Y Egashira T Nishiyama T Shin T Fujii 2006 A mono-2-ethylhexyl phthalate hydrolase from a Gordonia sp. that is able to dissimilate di-2-ethylhexyl phthalate Appl Environ Microbiol 72 2394 2399 10.1128/AEM.72.4.2394-2399.2006 1:CAS:528:DC%2BD28XktFagtL8%3D
    • (2006) Appl Environ Microbiol , vol.72 , pp. 2394-2399
    • Nishioka, T.1    Iwata, M.2    Imaoka, T.3    Mutoh, M.4    Egashira, Y.5    Nishiyama, T.6    Shin, T.7    Fujii, T.8
  • 30
    • 0029862514 scopus 로고    scopus 로고
    • Novel bacterial isolates for the resolution of esters of tertiary alcohols
    • DOI 10.1007/BF00129965
    • I Osprian A Steinreiber M Mischitz K Faber 1996 Novel bacterial isolates for the resolution of esters of tertiary alcohols Biotechnol Lett 18 1331 1334 10.1007/BF00129965 1:CAS:528:DyaK28XnsVWqs7k%3D (Pubitemid 26388568)
    • (1996) Biotechnology Letters , vol.18 , Issue.11 , pp. 1331-1334
    • Osprian, I.1    Steinreiber, A.2    Mischitz, M.3    Faber, K.4
  • 31
    • 67651229642 scopus 로고    scopus 로고
    • Mycobacteriophage Lysin B is a novel mycolylarabinogalactan esterase
    • 10.1111/j.1365-2958.2009.06775.x 1:CAS:528:DC%2BD1MXhtVWksbbE
    • K Payne Q Sun J Sacchettini GF Hatfull 2009 Mycobacteriophage Lysin B is a novel mycolylarabinogalactan esterase Mol Microbiol 73 367 381 10.1111/j.1365-2958.2009.06775.x 1:CAS:528:DC%2BD1MXhtVWksbbE
    • (2009) Mol Microbiol , vol.73 , pp. 367-381
    • Payne, K.1    Sun, Q.2    Sacchettini, J.3    Hatfull, G.F.4
  • 32
    • 0028114969 scopus 로고
    • Comparative analysis of the 16S rRNA gene sequence of the putative agent of proliferative ileitis of hamsters
    • TA Peace KV Brock HF Stills Jr. 1994 Comparative analysis of the 16S rRNA gene sequence of the putative agent of proliferative ileitis of hamsters Int J Syst Bacteriol 44 832 835 10.1099/00207713-44-4-832 1:CAS:528:DyaK2MXitFCnsLY%3D (Pubitemid 24315165)
    • (1994) International Journal of Systematic Bacteriology , vol.44 , Issue.4 , pp. 832-835
    • Peace, T.A.1    Brock, K.V.2    Stills Jr., H.F.3
  • 33
    • 0034684072 scopus 로고    scopus 로고
    • Biocatalytic resolution of sterically hindered alcohols, carboxylic acids and esters containing fully substituted chiral centers by hydrolytic enzymes
    • DOI 10.1016/S1381-1177(99)00121-6, PII S1381117799001216
    • M Pogorevc K Faber 2000 Biocatalytic resolution of sterically hindered alcohols, carboxylic acids and esters containing fully substituted chiral centers by hydrolytic enzymes J Mol Catal B Enzym 10 357 376 10.1016/S1381-1177(99)00121-6 1:CAS:528:DC%2BD3cXltlWgsbc%3D (Pubitemid 30483990)
    • (2000) Journal of Molecular Catalysis - B Enzymatic , vol.10 , Issue.4 , pp. 357-376
    • Pogorevc, M.1    Faber, K.2
  • 34
    • 0034392439 scopus 로고    scopus 로고
    • Novel carboxyl esterase preparations for the resolution of linalyl acetate
    • 1:CAS:528:DC%2BD3cXlt1Smsbo%3D
    • M Pogorevc U Strauss M Hayn K Faber 2000 Novel carboxyl esterase preparations for the resolution of linalyl acetate Chem Monthly 131 639 644 1:CAS:528:DC%2BD3cXlt1Smsbo%3D
    • (2000) Chem Monthly , vol.131 , pp. 639-644
    • Pogorevc, M.1    Strauss, U.2    Hayn, M.3    Faber, K.4
  • 36
    • 0030692705 scopus 로고    scopus 로고
    • Biodegradation of the gasoline oxygenates methyl tert-butyl ether, ethyl tert-butyl ether, and tert-amyl methyl ether by propane-oxidizing bacteria
    • R Steffan K McClay S Vainberg C Condee D Zhang 1997 Biodegradation of the gasoline oxygenates methyl tert-butyl ether, ethyl tert-butyl ether, and tert-amyl methyl ether by propane-oxidizing bacteria Appl Environ Microbiol 63 4216 4222 1:CAS:528:DyaK2sXnt12nsbs%3D (Pubitemid 27485742)
    • (1997) Applied and Environmental Microbiology , vol.63 , Issue.11 , pp. 4216-4222
    • Steffan, R.J.1    McClay, K.2    Vainberg, S.3    Condee, C.W.4    Zhang, D.5
  • 37
    • 57649120956 scopus 로고    scopus 로고
    • Enantiodivergent conversion of chiral secondary alcohols into tertiary alcohols
    • 10.1038/nature07592 1:CAS:528:DC%2BD1cXhsVymtrfJ
    • J Stymiest V Bagutski R French V Aggarwal 2008 Enantiodivergent conversion of chiral secondary alcohols into tertiary alcohols Nature 456 778 U761 10.1038/nature07592 1:CAS:528:DC%2BD1cXhsVymtrfJ
    • (2008) Nature , vol.456
    • Stymiest, J.1    Bagutski, V.2    French, R.3    Aggarwal, V.4
  • 39
    • 2942529079 scopus 로고    scopus 로고
    • Harnessing the catabolic diversity of rhodococci for environmental and biotechnological applications
    • DOI 10.1016/j.mib.2004.04.001, PII S1369527404000384
    • R van der Geize L Dijkhuizen 2004 Harnessing the catabolic diversity of rhodococci for environmental and biotechnological applications Curr Opin Microbiol 7 255 261 10.1016/j.mib.2004.04.001 (Pubitemid 38758066)
    • (2004) Current Opinion in Microbiology , vol.7 , Issue.3 , pp. 255-261
    • Van Der Geize, R.1    Dijkhuizen, L.2
  • 40
    • 67349283030 scopus 로고    scopus 로고
    • Derivatization of bioactive carbazoles by the biphenyl-degrading bacterium Ralstonia sp. strain SBUG 290
    • 10.1007/s00253-008-1853-z
    • D Waldau A Mikolasch M Lalk F Schauer 2008 Derivatization of bioactive carbazoles by the biphenyl-degrading bacterium Ralstonia sp. strain SBUG 290 Appl Microbiol Biotechnol 83 67 75 10.1007/s00253-008-1853-z
    • (2008) Appl Microbiol Biotechnol , vol.83 , pp. 67-75
    • Waldau, D.1    Mikolasch, A.2    Lalk, M.3    Schauer, F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.