Antisolvent crystallization of pharmaceutical excipients from aqueous solutions and the use of preferred orientation in phase identification by powder X-ray diffraction

European Journal of Pharmaceutical Sciences

Volumn 42, Issue 5, 2011, Pages 568-577

  Crisp, J L ^a   Dann, S E ^a   Blatchford, C G ^b  

^a LOUGHBOROUGH UNIVERSITY   (United Kingdom)

^b 3M Drug Delivery Systems   (United Kingdom)

Author keywords

Antisolvents; Crystallization; Excipients; Lactose; Powder X ray diffraction (PXRD); Scanning electron microscopy (SEM)

Indexed keywords

ACETONE; ACETONITRILE; ALCOHOL; ALPHA LACTOSE; ANTISOLVENT; BETA LACTOSE; EXCIPIENT; LACTOSE; MANNITOL; METHANOL; RAFFINOSE; SOLVENT; TETRAHYDROFURAN; TREHALOSE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; HYDRATION; PHASE TRANSITION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; X RAY POWDER DIFFRACTION;

CRYSTALLIZATION; ETHANOL; EXCIPIENTS; LACTOSE; METHANOL; PHASE TRANSITION; SOLUTIONS; SOLVENTS; WATER; X-RAY DIFFRACTION;

EID: 79954633013     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2011.02.010     Document Type: Article

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