IL6 and TNF expression in vessels and surrounding tissues after embolization with ibuprofen-loaded beads confirms diffusion of ibuprofen

European Journal of Pharmaceutical Sciences

Volumn 42, Issue 5, 2011, Pages 489-495

  Verret, Valentin ^a   Bevilacqua, Claudia ^b   Schwartz Cornil, Isabelle ^c   Pelage, Jean Pierre ^d   Wassef, Michel ^e   Namur, Julien ^a   Bédouet, Laurent ^f   Lewis, Andrew L ^g   Martin, Patrice ^b   Laurent, Alexandre ^a,c,e  

^a ParisBiotech   (France)

^b UMR1313 GÉNÉTIQUE ANIMALE ET BIOLOGIE INTÉGRATIVE   (France)

^c CEMAGREF   (France)

^d HÔPITAL AMBROISE PARÉ   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

^f Occlugel   (France)

^g BIOCOMPATIBLES UK LTD   (United Kingdom)

Author keywords

Drug delivery; Embolization; Ibuprofen; IL6; Quantitative PCR

Indexed keywords

IBUPROFEN; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL TISSUE; ARTERY OCCLUSION; ARTICLE; BLOOD VESSEL WALL; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG ELUTING BEAD; DRUG ELUTING STENT; GENE EXPRESSION; GENE EXPRESSION REGULATION; HISTOLOGY; LASER CAPTURE MICRODISSECTION; MICRODISSECTION; NONHUMAN; PAIN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; SHEEP; UTERINE ARTERY; UTERINE ARTERY EMBOLIZATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; FEMALE; GENE EXPRESSION; IBUPROFEN; INTERLEUKIN-6; LASERS; LEIOMYOMA; MICRODISSECTION; MICROSPHERES; PAIN, POSTOPERATIVE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SHEEP; TISSUE DISTRIBUTION; TUMOR NECROSIS FACTOR-ALPHA; UTERINE ARTERY; UTERINE ARTERY EMBOLIZATION; UTERINE NEOPLASMS; UTERUS;

EID: 79954631660     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2011.02.001     Document Type: Article

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