메뉴 건너뛰기




Volumn 52, Issue 5, 2011, Pages 877-886

Apoptotic induction in B-cell acute lymphoblastic leukemia cell lines treated with a protein kinase C inhibitor

Author keywords

Acute lymphoblastic leukemia; AKT; apoptosis; GSK3 ; protein kinase C ; targeted therapeutic

Indexed keywords

3 [1 (3 IMIDAZOL 1 YLPROPYL) 1H INDOL 3 YL] 4 ANILINO 1H PYRROLE 2,5 DIONE; ANTINEOPLASTIC AGENT; GLYCOGEN SYNTHASE KINASE 3BETA; ISOPROTEIN; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN KINASE B; PROTEIN KINASE C BETA INHIBITOR; UNCLASSIFIED DRUG;

EID: 79954626212     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2011.552136     Document Type: Article
Times cited : (6)

References (47)
  • 1
    • 52449086178 scopus 로고    scopus 로고
    • Lymphoma survival patterns by WHO subtype in the united states, 1973-2003
    • Han X, Kilfoy B, Zheng T, et al. Lymphoma survival patterns by WHO subtype in the United States, 1973-2003. Cancer Causes Control 2008;19:841-858.
    • (2008) Cancer Causes Control , vol.19 , pp. 841-858
    • Han, X.1    Kilfoy, B.2    Zheng, T.3
  • 2
    • 77953022239 scopus 로고    scopus 로고
    • Epidemiology of childhood cancer
    • Kaatsch P. Epidemiology of childhood cancer. Cancer Treat Rev 2010;36:277-285.
    • (2010) Cancer Treat Rev , vol.36 , pp. 277-285
    • Kaatsch, P.1
  • 3
    • 77149133679 scopus 로고    scopus 로고
    • Adult acute lymphoblastic leukemia: Concepts and strategies
    • Faderl S, O'Brien S, Pui CH, et al. Adult acute lymphoblastic leukemia: concepts and strategies. Cancer 2010;116:1165-1176.
    • (2010) Cancer , vol.116 , pp. 1165-1176
    • Faderl, S.1    O'Brien, S.2    Pui, C.H.3
  • 4
    • 0031042710 scopus 로고    scopus 로고
    • Treatment of adult acute lymphoblastic leukemia
    • Laport GF, Larson RA. Treatment of adult acute lymphoblastic leukemia. Semin Oncol 1997;24:70-82. (Pubitemid 27104905)
    • (1997) Seminars in Oncology , vol.24 , Issue.1 , pp. 70-82
    • Laport, G.F.1    Larson, R.A.2
  • 5
    • 77950664722 scopus 로고    scopus 로고
    • Outcome after relapse of acute lymphoblastic leukemia in adult patients included in four consecutive risk-adapted trials by the PETHEMA study group
    • Oriol A, Vives S, Hernandez-Rivas JM, et al. Outcome after relapse of acute lymphoblastic leukemia in adult patients included in four consecutive risk-adapted trials by the PETHEMA Study Group. Haematologica 2010;95:589-596.
    • (2010) Haematologica , vol.95 , pp. 589-596
    • Oriol, A.1    Vives, S.2    Hernandez-Rivas, J.M.3
  • 6
    • 0037303242 scopus 로고    scopus 로고
    • Haemopoietic stem cell transplantation for acute lymphoblastic leukaemia
    • DOI 10.1016/S0305-7372(02)00092-0
    • Popat U, Carrum G, Heslop HE. Haemopoietic stem cell transplantation for acute lymphoblastic leukaemia. Cancer Treat Rev 2003;29:3-10. (Pubitemid 36395518)
    • (2003) Cancer Treatment Reviews , vol.29 , Issue.1 , pp. 3-10
    • Popat, U.1    Carrum, G.2    Heslop, H.E.3
  • 10
    • 67651172962 scopus 로고    scopus 로고
    • Enzastaurin shows preclinical antitumor activity against human transitional cell carcinoma and enhances the activity of gemcitabine
    • Jian W, Yamashita H, Levitt JM, Lerner SP, Sonpavde G. Enzastaurin shows preclinical antitumor activity against human transitional cell carcinoma and enhances the activity of gemcitabine. Mol Cancer Ther 2009;8:1772-1778.
    • (2009) Mol Cancer Ther , vol.8 , pp. 1772-1778
    • Jian, W.1    Yamashita, H.2    Levitt, J.M.3    Lerner, S.P.4    Sonpavde, G.5
  • 11
    • 4143099402 scopus 로고    scopus 로고
    • Antisense targeting protein kinase C alpha and beta1 inhibits gastric carcinogenesis
    • Jiang XH, Tu SP, Cui JT, et al. Antisense targeting protein kinase C alpha and beta1 inhibits gastric carcinogenesis. Cancer Res 2004;64:5787-5794.
    • (2004) Cancer Res , vol.64 , pp. 5787-5794
    • Jiang, X.H.1    Tu, S.P.2    Cui, J.T.3
  • 12
    • 50849095153 scopus 로고    scopus 로고
    • Enzastaurin-induced apoptosis in glioma cells is caspase-dependent and inhibited by BCL-XL
    • Rieger J, Lemke D, Maurer G, et al. Enzastaurin-induced apoptosis in glioma cells is caspase-dependent and inhibited by BCL-XL. J Neurochem 2008;106:2436-2448.
    • (2008) J Neurochem , vol.106 , pp. 2436-2448
    • Rieger, J.1    Lemke, D.2    Maurer, G.3
  • 14
    • 50249122093 scopus 로고    scopus 로고
    • Molecular pathways involved in the synergistic interaction of the PKC beta inhibitor enzastaurin with the antifolate pemetrexed in non-small cell lung cancer cells
    • Tekle C, Giovannetti E, Sigmond J, Graff JR, Smid K, Peters GJ. Molecular pathways involved in the synergistic interaction of the PKC beta inhibitor enzastaurin with the antifolate pemetrexed in non-small cell lung cancer cells. Br J Cancer 2008;99:750-759.
    • (2008) Br J Cancer , vol.99 , pp. 750-759
    • Tekle, C.1    Giovannetti, E.2    Sigmond, J.3    Graff, J.R.4    Smid, K.5    Peters, G.J.6
  • 15
    • 62749137151 scopus 로고    scopus 로고
    • Synergistic effect of sorafenib and sunitinib with enzastaurin, a selective protein kinase C inhibitor in renal cell carcinoma cell lines
    • Vogl UM, Berger W, Micksche M, et al. Synergistic effect of sorafenib and sunitinib with enzastaurin, a selective protein kinase C inhibitor in renal cell carcinoma cell lines. Cancer Lett 2009;277:218-226.
    • (2009) Cancer Lett , vol.277 , pp. 218-226
    • Vogl, U.M.1    Berger, W.2    Micksche, M.3
  • 16
    • 63849093256 scopus 로고    scopus 로고
    • PKCbeta is essential for the development of chronic lymphocytic leukemia in the TCL1 transgenic mouse model: Validation of PKCbeta as a therapeutic target in chronic lymphocytic leukemia
    • Holler C, Pinon JD, Denk U, et al. PKCbeta is essential for the development of chronic lymphocytic leukemia in the TCL1 transgenic mouse model: validation of PKCbeta as a therapeutic target in chronic lymphocytic leukemia. Blood 2009;113:2791-2794.
    • (2009) Blood , vol.113 , pp. 2791-2794
    • Holler, C.1    Pinon, J.D.2    Denk, U.3
  • 18
    • 34250703569 scopus 로고    scopus 로고
    • Classical PKC isoforms in cancer
    • DOI 10.1016/j.phrs.2007.04.001, PII S1043661807000795
    • Martiny-Baron G, Fabbro D. Classical PKC isoforms in cancer. Pharmacol Res 2007;55:477-486. (Pubitemid 46970734)
    • (2007) Pharmacological Research , vol.55 , Issue.6 , pp. 477-486
    • Martiny-Baron, G.1    Fabbro, D.2
  • 19
    • 33745207996 scopus 로고    scopus 로고
    • The selective protein kinase C beta inhibitor enzastaurin induces apoptosis in cutaneous T-cell lymphoma cell lines through the AKT pathway
    • Querfeld C, Rizvi MA, Kuzel TM, et al. The selective protein kinase C beta inhibitor enzastaurin induces apoptosis in cutaneous T-cell lymphoma cell lines through the AKT pathway. J Invest Dermatol 2006;126:1641-1647.
    • (2006) J Invest Dermatol , vol.126 , pp. 1641-1647
    • Querfeld, C.1    Rizvi, M.A.2    Kuzel, T.M.3
  • 20
    • 61849179573 scopus 로고    scopus 로고
    • Targeting PKC: A novel role for beta-catenin in ER stress and apoptotic signaling
    • Raab MS, Breitkreutz I, Tonon G, et al. Targeting PKC: a novel role for beta-catenin in ER stress and apoptotic signaling. Blood 2009;113:1513-1521.
    • (2009) Blood , vol.113 , pp. 1513-1521
    • Raab, M.S.1    Breitkreutz, I.2    Tonon, G.3
  • 21
    • 84884308792 scopus 로고    scopus 로고
    • Protein kinase C and apoptosis
    • Srivastava R, editor Totowa, NJ: Humana Press, Inc
    • Reyland ME. Protein kinase C and apoptosis. In: Srivastava R, editor. Apoptosis, cell signaling and human disease. Totowa, NJ: Humana Press, Inc; 2007. pp 31-55.
    • (2007) Apoptosis, Cell Signaling and Human Disease , pp. 31-55
    • Reyland, M.E.1
  • 22
    • 33748328365 scopus 로고    scopus 로고
    • Enzastaurin (LY317615), a protein kinase Cβ inhibitor, inhibits the AKT pathway and induces apoptosis in multiple myeloma cell lines
    • DOI 10.1158/1535-7163.MCT-05-0465
    • Rizvi MA, Ghias K, Davies KM, et al. Enzastaurin (LY317615), a protein kinase Cbeta inhibitor, inhibits the AKT pathway and induces apoptosis in multiple myeloma cell lines. Mol Cancer Ther 2006;5:1783-1789. (Pubitemid 44323246)
    • (2006) Molecular Cancer Therapeutics , vol.5 , Issue.7 , pp. 1783-1789
    • Rizvi, M.A.1    Ghias, K.2    Davies, K.M.3    Ma, C.4    Weinberg, F.5    Munshi, H.G.6    Krett, N.L.7    Rosen, S.T.8
  • 24
    • 65249135021 scopus 로고    scopus 로고
    • Molecular targeting of the PKC-beta inhibitor enzastaurin (LY317615) in multiple myeloma involves a coordinated downregulation of MYC and IRF4 expression
    • Verdelli D, Nobili L, Todoerti K, et al. Molecular targeting of the PKC-beta inhibitor enzastaurin (LY317615) in multiple myeloma involves a coordinated downregulation of MYC and IRF4 expression. Hematol Oncol 2009;27:23-30.
    • (2009) Hematol Oncol , vol.27 , pp. 23-30
    • Verdelli, D.1    Nobili, L.2    Todoerti, K.3
  • 25
    • 2342493308 scopus 로고    scopus 로고
    • Protein kinase C family functions in B-cell activation
    • DOI 10.1016/j.coi.2004.03.012, PII S0952791504000494
    • Guo B, Su TT, Rawlings DJ. Protein kinase C family functions in B-cell activation. Curr Opin Immunol 2004;16: 367-373. (Pubitemid 38595376)
    • (2004) Current Opinion in Immunology , vol.16 , Issue.3 , pp. 367-373
    • Guo, B.1    Su, T.T.2    Rawlings, D.J.3
  • 26
  • 27
    • 34848833908 scopus 로고    scopus 로고
    • Enzastaurin
    • DOI 10.1097/CCO.0b013e3282f10a00, PII 0000162220071100000009
    • Ma S, Rosen ST. Enzastaurin. Curr Opin Oncol 2007;19: 590-595. (Pubitemid 47508866)
    • (2007) Current Opinion in Oncology , vol.19 , Issue.6 , pp. 590-595
    • Ma, S.1    Rosen, S.T.2
  • 32
    • 37549011707 scopus 로고    scopus 로고
    • IkappaB kinase beta-induced phosphorylation of CARMA1 contributes to CARMA1 bcl10 MALT1 complex formation in B cells
    • Shinohara H, Maeda S, Watarai H, Kurosaki T. IkappaB kinase beta-induced phosphorylation of CARMA1 contributes to CARMA1 Bcl10 MALT1 complex formation in B cells. J Exp Med 2007;204:3285-3293.
    • (2007) J Exp Med , vol.204 , pp. 3285-3293
    • Shinohara, H.1    Maeda, S.2    Watarai, H.3    Kurosaki, T.4
  • 33
    • 0036344276 scopus 로고    scopus 로고
    • PKC-beta controls I kappa B kinase lipid raft recruitment and activation in response to BCR signaling
    • Su TT, Guo B, Kawakami Y, et al. PKC-beta controls I kappa B kinase lipid raft recruitment and activation in response to BCR signaling. Nat Immunol 2002;3:780-786.
    • (2002) Nat Immunol , vol.3 , pp. 780-786
    • Su, T.T.1    Guo, B.2    Kawakami, Y.3
  • 35
    • 0025167963 scopus 로고
    • Overexpression of protein kinase C in HT29 colon cancer cells causes growth inhibition and tumor suppression
    • Choi PM, Tchou-Wong KM, Weinstein IB. Overexpression of protein kinase C in HT29 colon cancer cells causes growth inhibition and tumor suppression. Mol Cell Biol 1990;10: 4650-4657.
    • (1990) Mol Cell Biol , vol.10 , pp. 4650-4657
    • Choi, P.M.1    Tchou-Wong, K.M.2    Weinstein, I.B.3
  • 38
    • 0036022402 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: An update
    • DOI 10.1023/A:1016119328968
    • Soldani C, Scovassi AI. Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: an update. Apoptosis 2002;7:321-328. (Pubitemid 34832256)
    • (2002) Apoptosis , vol.7 , Issue.4 , pp. 321-328
    • Soldani, C.1    Scovassi, A.I.2
  • 41
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • DOI 10.1038/378785a0
    • Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 1995;378:785-789. (Pubitemid 26004411)
    • (1995) Nature , vol.378 , Issue.6559 , pp. 785-789
    • Cross, D.A.E.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 43
    • 13544266554 scopus 로고    scopus 로고
    • New insight into the molecular mechanisms of MLL-associated leukemia
    • Li ZY, Liu DP, Liang CC. New insight into the molecular mechanisms of MLL-associated leukemia. Leukemia 2005;19: 183-190.
    • (2005) Leukemia , vol.19 , pp. 183-190
    • Li, Z.Y.1    Liu, D.P.2    Liang, C.C.3
  • 44
    • 0033517244 scopus 로고    scopus 로고
    • Akt is more than just a bad kinase
    • Khwaja A. Akt is more than just a Bad kinase. Nature 1999;401:33-34.
    • (1999) Nature , vol.401 , pp. 33-34
    • Khwaja, A.1
  • 45
    • 40949101463 scopus 로고    scopus 로고
    • Enzastaurin, a protein kinase C beta inhibitor, suppresses signaling through the ribosomal S6 kinase and bad pathways and induces apoptosis in human gastric cancer cells
    • Lee KW, Kim SG, Kim HP, et al. Enzastaurin, a protein kinase C beta inhibitor, suppresses signaling through the ribosomal S6 kinase and bad pathways and induces apoptosis in human gastric cancer cells. Cancer Res 2008;68:1916-1926.
    • (2008) Cancer Res , vol.68 , pp. 1916-1926
    • Lee, K.W.1    Kim, S.G.2    Kim, H.P.3
  • 46
    • 33947264162 scopus 로고    scopus 로고
    • PI3K, RSK, and mTOR signal networks for the GST gene regulation
    • DOI 10.1093/toxsci/kfl175
    • Kim SG, Lee SJ. PI3K, RSK, and mTOR signal networks for the GST gene regulation. Toxicol Sci 2007;96:206-213. (Pubitemid 46432017)
    • (2007) Toxicological Sciences , vol.96 , Issue.2 , pp. 206-213
    • Kim, S.G.1    Lee, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.