Early weaning increases diarrhea morbidity and mortality among uninfected children born to HIV-infected mothers in Zambia

Journal of Infectious Diseases

Volumn 203, Issue 9, 2011, Pages 1222-1230

  Fawzy, Ashraf ^a   Arpadi, Stephen ^a   Kankasa, Chipepo ^b   Sinkala, Moses ^c   Mwiya, Mwiya ^b   Thea, Donald M ^d   Aldrovandi, Grace M ^e   Kuhn, Louise ^a  

^a Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Gertrude H Sergievsky Center   (United States)

^b UNIVERSITY TEACHING HOSPITAL   (Zambia)

^c Lusaka District Health Management Team   (Zambia)

^d BOSTON UNIVERSITY   (United States)

^e CHILDREN S HOSPITAL LOS ANGELES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGE; ARTICLE; BREAST FEEDING; CONTROLLED STUDY; DIARRHEA; FEMALE; HOSPITALIZATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFANT; INFANT MORTALITY; INFANT NUTRITION; MALE; MORBIDITY; NEWBORN; NUTRITIONAL COUNSELING; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; RISK REDUCTION; ZAMBIA;

CHILD, PRESCHOOL; DIARRHEA; FEMALE; HIV INFECTIONS; HUMANS; INFANT; INFANT, NEWBORN; MALE; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; SURVIVAL ANALYSIS; WEANING; ZAMBIA;

EID: 79954607070     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jir019     Document Type: Article

References (46)

1. Feachem RG, Koblinsky MA. Interventions for the control of diarrhoeal diseases among young children: promotion of breast-feeding. Bull World Health Organ 1984;62:271-91. (Pubitemid 14113762)
2. Monterrosa EC, Frongillo EA, Vasquez-Garibay EM, Romero-Velarde E, Casey LM, Willows ND. Predominant breast-feeding from birth to six months is associated with fewer gastrointestinal infections and increased risk for iron deficiency among infants. J Nutr 2008;138:1499-504.
3. Myers MG, Fomon SJ, Koontz FP, McGuinness GA, Lachenbruch PA, Hollingshead R. Respiratory and gastrointestinal illnesses in breastand formula-fed infants. Am J Dis Child 1984;138:629-32. (Pubitemid 14080790)
4. Sethi D, Cumberland P, Hudson MJ, et al. A study of infectious intestinal disease in England: risk factors associated with group A rotavirus in children. Epidemiol Infect 2001;126:63-70. (Pubitemid 32266428)
5. Kosek M, Bern C, Guerrant RL. The global burden of diarrhoeal disease, as estimated from studies published between 1992 and 2000. Bull World Health Organ 2003;81:197-204. (Pubitemid 36372958)
6. Kuhn L, Aldrovandi G, Sinkala M, et al. Effects of early, abrupt weaning on HIV-free survival of children in Zambia. N Engl J Med 2008;359:130-41. (Pubitemid 351962036)
7. Kuhn L, Sinkala M, Semrau K, et al. Elevations in mortality associated with weaning persist into the second year of life among uninfected children born to HIV-infected mothers. Clin Infect Dis 2010;50:437-44.
8. Kuhn L, Aldrovandi GM, Sinkala M, et al. Differential effects of early weaning for HIV-free survival of children born to HIV-infected mothers by severity of maternal disease. PLoS One 2009;4:e6059.
9. Arpadi S, Fawzy A, Aldrovandi GM, et al. Growth faltering due to breastfeeding cessation in uninfected children born to HIV-infected mothers in Zambia. Am J Clin Nutr 2009;90:344-53.
10. Kuhn L, Sinkala M, Kankasa C, et al. High uptake of exclusive breastfeeding and reduced early post-natal HIV transmission. PLoS One 2007;2:e1363.
11. Thea D, Vwalika C, Kasonde P, et al. Issues in the design of a clinical trial with a behavioral intervention-the Zambia exclusive breastfeeding study. Control Clin Trials 2004;25:353-65. (Pubitemid 39013971)
12. Ghosh MK, Kuhn L, West J, et al. Quantitation of human immunodeficiency virus type 1 in breast milk. J Clin Microbiol 2003;41:2465-70. (Pubitemid 36712453)
13. Zambia Meteorological Department. World Weather Information Service-Lusaka http://worldweather.wmo.int/040/c00150.htm. Accessed 10 October 2008.
14. Black R. Persistent diarrhea in children of developing countries. Pediatr Infect Dis J 1993;12:751-61.
15. Maldonado G, Greenland S. Simulation study of confounder-selection strategies. Am J Epidemiol 1993;138:923-36. (Pubitemid 24002359)
16. Honda Y, Macaluso M, Brill I. A SAS program for the stratified analysis of follow-up data. J Occup Health 1998;40:154-7. (Pubitemid 128547419)
17. Ahiadeke C. Breast-feeding, diarrhoea and sanitation as components of infant and child health: a study of large scale survey data from Ghana and Nigeria. J Biosoc Sci 2000;32:47-61. (Pubitemid 30047539)
18. Bhandari N, Bahl R, Mazumdar S, Martines J, Black R, Bhan M. Effect of community-based promotion of exclusive breastfeeding on diarrhoeal illness and growth: a cluster randomised controlled trial. Lancet 2003;361:1418-23. (Pubitemid 36515042)
19. Brown K, Black R, Lopez de Romaña G, Creed de Kanashiro H. Infantfeeding practices and their relationship with diarrheal and other diseases in Huascar (Lima), Peru. Pediatrics 1989;83:31-40.
20. Effect of breastfeeding on infant and child mortality due to infectious diseases in less developed countries: a pooled analysis. WHO Collaborative Study Team on the Role of Breastfeeding on the Prevention of Infant Mortality. Lancet 2000;355:451-5.
21. Arifeen S, Black R, Antelman G, Baqui A, Caulfield L, Becker S. Exclusive breastfeeding reduces acute respiratory infection and diarrhea deaths among infants in Dhaka slums. Pediatrics 2001;108:E67.
22. Bahl R, Frost C, Kirkwood B, et al. Infant feeding patterns and risks of death and hospitalization in the first half of infancy: multicentre cohort study. Bull World Health Organ 2005;83:418-26. (Pubitemid 40868438)
23. Yoon P, Black R, Moulton L, Becker S. Effect of not breastfeeding on the risk of diarrheal and respiratory mortality in children under 2 years of age in Metro Cebu, the Philippines. Am J Epidemiol 1996;143:1142-8. (Pubitemid 26158111)
24. Kourtis A, Fitzgerald D, Hyde L, et al. Diarrhea in uninfected infants of HIV-infected mothers who stop breastfeeding at 6 months: the BAN study experience 772. 14th CROI. Los Angeles, 2007.
25. Onyango-Makumbi C, Bagenda D, Mwatha A, et al. Early weaning of HIV-exposed uninfected infants and risk of serious gastroenteritis: findings from two perinatal HIV prevention trials in Kampala, Uganda. J Acquir Immune Defic Syndr 2010;53:20-7.
26. Harris JR, Greene SK, Thomas TK, et al. Effect of a point-of-use water treatment and safe water storage intervention on diarrhea in infants of HIV-infected mothers. J Infect Dis 2009;200:1186-93.
27. Kafulafula G, Hoover DR, Taha TE, et al. Frequency of gastroenteritis and gastroenteritis-associated mortality with early weaning in HIV-1-uninfected children born to HIV-infected women in Malawi. J Acquir Immune Defic Syndr 2010;53:6-13.
28. Bhandari N, Bhan M, Sazawal S. Mortality associated with acute watery diarrhea, dysentery and persistent diarrhea in rural North India. Acta Paediatr Suppl 1992;381:3-6.
29. Fauveau V, Henry F, Briend A, Yunus M, Chakraborty J. Persistent diarrhea as a cause of childhood mortality in rural Bangladesh. Acta Paediatr Suppl 1992;381:12-4.
30. Petri WJ, Miller M, Binder H, Levine M, Dillingham R, Guerrant R. Enteric infections, diarrhea, and their impact on function and development. J Clin Invest 2008;118:1277-90. (Pubitemid 351500420)
31. Checkley W, Buckley G, Gilman R, et al. Multi-country analysis of the effects of diarrhoea on childhood stunting. Int J Epidemiol 2008;37:814-30.
32. Mihrshahi S, Oddy W, Peat J, Kabir I. Association between infant feeding patterns and diarrhoeal and respiratory illness: a cohort study in Chittagong, Bangladesh. Int Breastfeeding J 2008;3:28.
33. Brooks J, Ochieng J, Kumar L, et al. Surveillance for bacterial diarrhea and antimicrobial resistance in rural western Kenya, 1997-2003. Clin Infect Dis 2006;43:393-401. (Pubitemid 44157144)
34. Marino D. Water and food safety in the developing world: global implications for health and nutrition of infants and young children. J Am Diet Assoc 2007;107:1930-4. (Pubitemid 47614929)
35. Motarjemi Y, Käferstein F, Moy G, Quevedo F. Contaminated weaning food: a major risk factor for diarrhoea and associated malnutrition. Bull World Health Organ 1993;71:79-92. (Pubitemid 23075966)
36. Morrow AL, Rangel JM. Human milk protection against infectious diarrhea: implications for prevention and clinical care. Semin Pediatr Infect Dis 2004;15:221-8. (Pubitemid 39371102)
37. Mølbak K, Jensen H, Ingholt L, Aaby P. Risk factors for diarrheal disease incidence in early childhood: a community cohort study from Guinea-Bissau. Am J Epidemiol 1997;146:273-82. (Pubitemid 27329729)
38. Rowland M. The Gambia and Bangladesh: the seasons and diarrhoea. Dialogue Diarrhoea 1986;26:3.
39. Creek TL, Kim A, Lu L, et al. Hospitalization and mortality among primarily nonbreastfed children during a large outbreak of diarrhea and malnutrition in Botswana. J Acquir Immune Defic Syndr 2006;53:14-9.
40. Mach O, Lu L, Creek T, et al. Population-based study of a widespread outbreak of diarrhea associated with increased mortality and malnutrition in Botswana, January-March, 2006. Am J Trop Med Hyg 2009;80:812-8.
41. Plate D, Strassmann B, Wilson M. Water sources are associated with childhood diarrhoea prevalence in rural east-central Mali. Trop Med Int Health 2004;9:416-25. (Pubitemid 38365742)
42. World Health Organization. Diarrhoeal disease control programme. Persistent diarrhea in children-research priorities, Geneva: World Health Organization 1985.
43. Alam N, Henry F, Rahaman M. Reporting errors in one-week diarrhoea recall surveys: experience from a prospective study in rural Bangladesh. Int J Epidemiol 1989;18:697-700. (Pubitemid 19268619)
44. Melo M, Taddei J, Diniz-Santos D, May D, Carneiro N, Silva L. Incidence of diarrhea: poor parental recall ability. Braz J Infect Dis 2007;11:571-9.
45. Ramakrishnan R, Venkatarao T, Koya P, Kamaraj P. Influence of recall period on estimates of diarrhoea morbidity in infants in rural Tamil Nadu. Indian J Public Health 1998;42:3-6. (Pubitemid 128146700)
46. World Health Organization. Guidelines on HIV and infant feeding 2010. Principles and recommendations for infant feeding in the context of HIV and a summary of evidence. Geneva: WHO; 2010.