Discovery and SAR of a series of agonists at orphan G protein-coupled receptor 139

ACS Medicinal Chemistry Letters

Volumn 2, Issue 4, 2011, Pages 303-306

  Shi, Feng ^a   Shen, Jing Kang ^a   Chen, Danqi ^a   Fog, Karina ^c   Thirstrup, Kenneth ^c   Hentzer, Morten ^c   Karlsson, Jens Jakob ^c   Menon, Veena ^b   Jones, Kenneth A ^b   Smith, Kelli E ^b   Smith, Garrick ^c  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b LUNDBECK RESEARCH USA   (United States)

^c H LUNDBECK A S   (Denmark)

Author keywords

agonists; CNS; G protein coupled receptor; hydrazinecarboxamide; Orphan GPR 139

Indexed keywords

G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 139; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG EXPOSURE; DRUG POTENCY; DRUG SCREENING; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION; SURFACE PROPERTY;

RATTUS;

EID: 79954584864     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml100293q     Document Type: Article

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