Central benzodiazepine receptor binding potential and CBF images on spect correlate with oxygen extraction fraction images on PET in the cerebral cortex with unilateral major cerebral artery occlusive disease

Journal of Nuclear Medicine

Volumn 52, Issue 4, 2011, Pages 511-518

  Chida, Kohei ^a   Ogasawara, Kuniaki ^a   Kuroda, Hiroki ^a   Aso, Kenta ^a   Kobayashi, Masakazu ^a   Fujiwara, Shunrou ^a   Yoshida, Kenji ^a   Terasaki, Kazunori ^a   Ogawa, Akira ^a  

^a IWATE MEDICAL UNIVERSITY   (Japan)

Author keywords

123I iomazenil; Cerebral blood flow; Oxygen extraction fraction

Indexed keywords

BENZODIAZEPINE RECEPTOR; IOFETAMINE I 123; IOMAZENIL I 123; OXYGEN 15; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BASAL GANGLION; BRAIN ARTERY; BRAIN BLOOD FLOW; BRAIN CORTEX; BRAIN MAPPING; BRAIN REGION; CEREBELLUM; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG DISTRIBUTION; DRUG RECEPTOR BINDING; FEMALE; HUMAN; IMAGE ANALYSIS; MALE; OCCLUSIVE CEREBROVASCULAR DISEASE; OXYGEN EXTRACTION FRACTION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STANDARDIZATION;

ADULT; AGED; ARTERIAL OCCLUSIVE DISEASES; BASAL GANGLIA; CAROTID STENOSIS; CEREBELLUM; CEREBRAL CORTEX; CEREBROVASCULAR CIRCULATION; FEMALE; FLUMAZENIL; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; INFARCTION, MIDDLE CEREBRAL ARTERY; INTRACRANIAL ARTERIAL DISEASES; IOFETAMINE; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; OXYGEN CONSUMPTION; OXYGEN RADIOISOTOPES; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; RECEPTORS, GABA-A; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 79954574470     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.110.084186     Document Type: Article

References (39)

1. Gibbs JM, Wise RJ, Leenders KL, Jones T. Evaluation of cerebral perfusion reserve in patients with carotid-artery occlusion. Lancet. 1984;1:310-314. (Pubitemid 14185337)
2. Powers WJ, Raichle ME. Positron emission tomography and its application to the study of cerebrovascular disease in man. Stroke. 1985;16:361-376. (Pubitemid 15034415)
3. Baron JC, Bousser MG, Rey A, Guillard A, Comar D, Castaigne P. Reversal of focal "misery-perfusion syndrome" by extra-intracranial arterial bypass in hemodynamic cerebral ischemia: A case study with 15O positron emission tomography. Stroke. 1981;12:454-459. (Pubitemid 11046690)
4. Powers WJ. Cerebral hemodynamics in ischemic cerebrovascular disease. Ann Neurol. 1991;29:231-240.
5. Yamauchi H, Fukuyama H, Nagahama Y, et al. Evidence of misery perfusion and risk for recurrent stroke in major cerebral arterial occlusive diseases from PET. J Neurol Neurosurg Psychiatry. 1996;61:18-25. (Pubitemid 26232022)
6. Yamauchi H, Fukuyama H, Nagahama Y, et al. Significance of increased oxygen extraction fraction in 5-year prognosis of major cerebral arterial occlusive diseases. J Nucl Med. 1999;40:1992-1998. (Pubitemid 30022012)
7. Grubb RL Jr, Derdeyn CP, Fritsch SM, et al. Importance of hemodynamic factors in the prognosis of symptomatic carotid occlusion. JAMA. 1998;280:1055-1060. (Pubitemid 28449534)
8. Nemoto EM, Yonas H, Kuwabara H, et al. Identification of hemodynamic compromise by cerebrovascular reserve and oxygen extraction fraction in occlusive vascular disease. J Cereb Blood Flow Metab. 2004;24:1081-1089. (Pubitemid 39332147)
9. Yamauchi H, Okazawa H, Kishibe Y, Sugimoto K, Takahashi M. Oxygen extraction fraction and acetazolamide reactivity in symptomatic carotid artery disease. J Neurol Neurosurg Psychiatry. 2004;75:33-37. (Pubitemid 38091265)
10. Kuroda S, Houkin K, Kamiyama H, Mitsumori K, Iwasaki Y, Abe H. Long-term prognosis of medically treated patients with internal carotid or middle cerebral artery occlusion: Can acetazolamide test predict it? Stroke. 2001;32:2110-2116.
11. Ogasawara K, Ogawa A, Yoshimoto T. Cerebrovascular reactivity to acetazolamide and outcome in patients with symptomatic internal carotid or middle cerebral artery occlusion: A xenon-133 single-photon emission computed tomography study. Stroke. 2002;33:1857-1862. (Pubitemid 34761076)
12. Derick RJ. Carbonic anhydrase inhibitors. In: Mauger TF, Craig EL, eds. Hevener's Ocular Pharmacology. 6th ed. St Louis, MO: CV Mosby Co.;1994: Chap. 4.
13. Ogasawara K, Tomitsuka N, Kobayashi M, et al. Stevens-Johnson syndrome associated with intravenous acetazolamide administration for evaluation of cerebrovascular reactivity: Case report. Neurol Med Chir (Tokyo). 2006;46:161-163.
14. Yamauchi H, Kudoh T, Kishibe Y, Iwasaki J, Kagawa S. Selective neuronal damage and borderzone infarction in carotid artery occlusive disease: A 11Cflumazenil PET study. J Nucl Med. 2005;46:1973-1979. (Pubitemid 46657442)
15. Millet P, Graf C, Moulin M, Ibanez V. SPECT quantification of benzodiazepine receptor concentration using a dual-ligand approach. J Nucl Med. 2006;47: 783-792. (Pubitemid 46768441)
16. Nakagawara J, Sperling B, Lassen NA. Incomplete brain infarction of reperfused cortex may be quantitated with iomazenil. Stroke. 1997;28:124-132. (Pubitemid 27039476)
17. Hatazawa J, Satoh T, Shimosegawa E, et al. Evaluation of cerebral infarction with iodine 123-iomazenil SPECT. J Nucl Med. 1995;36:2154-2161.
18. Hatazawa J, Shimosegawa E, Satoh T, Kanno I, Uemura K. Central benzodiazepine receptor distribution after subcortical hemorrhage evaluated by means of [123I]iomazenil and SPECT. Stroke. 1995;26:2267-2271.
19. Guadagno JV, Jones PS, Aigbirhio FI, et al. Selective neuronal loss in rescued penumbra relates to initial hypoperfusion. Brain. 2008;131:2666-2678.
20. Yamauchi H, Nishii R, Higashi T, Kagawa S, Fukuyama HJ. Silent cortical neuronal damage in atherosclerotic disease of the major cerebral arteries. J Cereb Blood Flow Metab. 2011;31:953-961.
21. Dong Y, Fukuyama H, Nabatame H, Yamauchi H, Shibasaki H, Yonekura Y. Assessment of benzodiazepine receptors using iodine-123-labeled iomazenil single- photon emission computed tomography in patients with ischemic cerebrovascular disease: A comparison with PET study. Stroke. 1997;28:1776-1782. (Pubitemid 27391449)
22. Yamauchi H, Nishii R, Higashi T, Kagawa S, Fukuyama H. Selective neuronal damage and Wisconsin Card Sorting Test performance in atherosclerotic occlusive disease of the major cerebral artery. J Neurol Neurosurg Psychiatry., in press.
23. Ibaraki M, Miura S, Shimosegawa E, et al. Quantification of cerebral blood flow and oxygen metabolism with 3-dimensional PET and 15O: Validation by comparison with 2-dimensional PET. J Nucl Med. 2008;49:50-59.
24. Frackowiak RS, Lenzi GL, Jones T, Heather JD. Quantitative measurement of regional cerebral blood flow and oxygen metabolism in man using 15O and positron emission tomography: Theory, procedure, and normal values. J Comput Assist Tomogr. 1980;4:727-736. (Pubitemid 11247403)
25. Lammertsma AA, Jones T. Correction for the presence of intravascular oxygen-15 in the steady-state technique for measuring regional oxygen extraction ratio in the brain: 1. Description of the method. J Cereb Blood Flow Metab. 1983;3:416-424. (Pubitemid 14182285)
26. Ogasawara K, Ito H, Sasoh M, et al. Quantitative measurement of regional cerebrovascular reactivity to acetazolamide using [123I]iodoamphetamine autoradiographic method with single photon emission computed tomography: Validation study using [15O] H2O positron emission tomography. J Nucl Med.2003;44:520-525.
27. Friston KJ, Frith CD, Liddle PF, Dolan RJ, Lammertsma AA, Frackowiak RS. The relationship between global and local changes in PET scans. J Cereb Blood Flow Metab. 1990;10:458-466. (Pubitemid 20209192)
28. Takeuchi R, Matsuda H, Yoshioka K, Yonekura Y. Cerebral blood flow SPET in transient global amnesia with automated ROI analysis by 3DSRT. Eur J Nucl Med Mol Imaging. 2004;31:578-589. (Pubitemid 38461574)
29. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986;1:307-310. (Pubitemid 16134762)
30. Bremner JD, Baldwin R, Horti A, et al. Quantitation of benzodiazepine receptor binding with PET [11C]iomazenil and SPECT [123I]iomazenil: Preliminary results of a direct comparison in healthy human subjects. Psychiatry Res. 1999;91:79-91. (Pubitemid 29433814)
31. Woods SW, Seibyl JP, Goddard AW, et al. Dynamic SPECT imaging after injection of the benzodiazepine receptor ligand [123I]iomazenil in healthy human subjects. Psychiatry Res. 1992;45:67-77.
32. Busatto GF, Pilowsky LS, Costa DC, Ell PJ, Lingford-Hughes A, Kerwin RW. In vivo imaging of GABAA receptors using sequential whole-volume iodine-123 iomazenil single-photon emission tomography. Eur J Nucl Med. 1995;22:12-16.
33. Braestrup C, Albrechtsen R, Squires RF. High densities of benzodiazepine receptors in human cortical areas. Nature. 1977;269:702-704. (Pubitemid 8186758)
34. Richards JG, Möhler H. Benzodiazepine receptors. Neuropharmacology. 1984; 23:233-242. (Pubitemid 14197479)
35. Zezula J, Cortes R, Probst A, Palacios JM. Benzodiazepine receptor sites in the human brain: Autoradiographic mapping. Neuroscience. 1988;25:771-795.
36. Baron JC, Bousser MG, Comar D, Soussaline F, Castaigne P. 'Crossed cerebellar diaschisis': A remote functional suppression secondary to supratentorial infarction in man [abstract]. J Cereb Blood Flow Metab. 1981;1:s500.
37. Reinhard M, Muller T, Roth M, Guschlbauer B, Timmer J, Hetzel A. Bilateral severe carotid artery stenosis or occlusion: Cerebral autoregulation dynamics and collateral flow patterns. Acta Neurochir (Wien). 2003;145:1053-1060. (Pubitemid 38091020)
38. Tanaka M, Shimosegawa E, Kajimoto K, et al. Chronic middle cerebral artery occlusion: A hemodynamic and metabolic study with positron-emission tomography. AJNR. 2008;29:1841-1846.
39. Ito H, Inoue K, Goto R, et al. Normal database of cerebral blood flow measured by SPECT with I-123-IMP, Tc-99m-HMPAO, and Tc-99m-ECD and PET with O-15 labeled water in humans: Comparison with voxel-based morphometry [abstract]. J Cereb Blood Flow Metab. 2005;25:S330.