Quantitation of benzodiazepine receptor binding with PET [11C]iomazenil and SPECT [123I]iomazenil: preliminary results of a direct comparison in healthy human subjects

Psychiatry Research - Neuroimaging

Volumn 91, Issue 2, 1999, Pages 79-91

  Bremner, J Douglas ^a,b   Baldwin, Ronald ^a,b   Horti, Andrew ^b   Staib, Lawrence H ^a   Ng, Chin K ^a,b   Tan, Ping Zhong ^a,b   Zea Ponce, Yolanda ^a,b   Zoghbi, Sami ^a   Seibyl, John P ^a   Soufer, Robert ^a,b   Charney, Dennis S ^a,b   Innis, Robert B ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

Author keywords

Benzodiazepine receptor binding; Compartmental modeling; Kinetic rate constants; Methodology; Positron emission tomography; Single photon emission computed tomography

Indexed keywords

BENZODIAZEPINE RECEPTOR; CARBON 11; IODINE 123; IOMAZENIL;

ADULT; ARTICLE; CLINICAL TRIAL; COMPARTMENT MODEL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORPUS STRIATUM; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG DISTRIBUTION; DRUG RECEPTOR BINDING; FRONTAL CORTEX; HUMAN; HUMAN EXPERIMENT; IMAGING; INTERMETHOD COMPARISON; INTRAVENOUS DRUG ADMINISTRATION; MALE; METHODOLOGY; NORMAL HUMAN; OCCIPITAL CORTEX; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TEMPORAL CORTEX;

ADULT; BINDING, COMPETITIVE; BIOLOGICAL ASSAY; BRAIN; FLUMAZENIL; HEALTH STATUS; HUMANS; MALE; RADIOLIGAND ASSAY; RADIOPHARMACEUTICALS; RECEPTORS, GABA-A; TIME FACTORS; TOMOGRAPHY, EMISSION-COMPUTED; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 0032855159     PISSN: 09254927     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4927(99)00015-3     Document Type: Article

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