C5-hydroxylation of liquiritigenin is catalyzed selectively by CYP1A2

Xenobiotica

Volumn 41, Issue 5, 2011, Pages 349-357

  Wang, Ao Xue ^a   Hu, Ying ^b   Liu, Hui Xin ^c   Qi, Xiao Yi ^a   Liu, Yong ^b   Tu, Cai Xia ^a   Yang, Ling ^b  

^a DALIAN MEDICAL UNIVERSITY   (China)

^b DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

^c UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

cytochrome P450; human liver microsomes; Liquiritigenin; metabolism

Indexed keywords

AURANTIIN; CYTOCHROME P450 1A2; DRUG METABOLITE; LIQUIRITIGENIN;

ARTICLE; DRUG HYDROXYLATION; DRUG OXIDATION; DRUG STRUCTURE; ENZYME MECHANISM; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER MICROSOME; TANDEM MASS SPECTROMETRY;

ADULT; ANIMALS; BIOCATALYSIS; CARBON; CHROMATOGRAPHY, LIQUID; CYTOCHROME P-450 CYP1A2; ENZYME INHIBITORS; FLAVANONES; HUMANS; HYDROXYLATION; KINETICS; MALE; MASS SPECTROMETRY; MICROSOMES, LIVER; MIDDLE AGED; RATS; RECOMBINANT PROTEINS;

RATTUS;

EID: 79954501822     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498254.2010.546014     Document Type: Article

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