MUC1-positive circulating tumor cells and MUC1 protein predict chemotherapeutic efficacy in the treatment of metastatic breast cancer

Chinese Journal of Cancer

Volumn 30, Issue 1, 2011, Pages 54-61

  Cheng, Jian Ping ^a   Yan, Ying ^a   Wang, Xiang Yi ^a   Lu, Yuan Li ^a   Yuan, Yan Hua ^a   Jia, Jun ^a   Ren, Jun ^a  

^a PEKING UNIVERSITY CANCER HOSPITAL AND INSTITUTE   (China)

Author keywords

Breast cancer; Circulating tumor cells; MUC1; RT PCR

Indexed keywords

DOCETAXEL; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; MUCIN 1; THIOTEPA;

ADULT; AGED; ARTICLE; BLOOD ANALYSIS; BONE METASTASIS; BREAST CANCER; CANCER CHEMOTHERAPY; CELL STRAIN MCF 7; CLINICAL ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG EFFICACY; DRUG RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; LIVER METASTASIS; LUNG METASTASIS; LYMPH NODE METASTASIS; METASTASIS; METASTATIC BREAST CANCER; OUTCOME ASSESSMENT; PLEURA METASTASIS; PREDICTION; PROGRESSION FREE SURVIVAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THORAX WALL CANCER; THORAX WALL METASTASIS; TUMOR EMBOLISM;

EID: 79954466229     PISSN: 1000467X     EISSN: 1944446X     Source Type: Journal    
DOI: 10.5732/cjc.010.10239     Document Type: Article

References (25)

1. Veronesi U, Boyle P, Goldhirsch A, et al. Breast cancer [J]. Lancet, 2005,365(9472):1727-1741.
2. Peto R, Boreham J, Clarke M, et al. UK and USA breast cancer deaths down 25% in year 2000 at ages 20-69 years [J]. Lancet, 2000,355(9217):1822.
3. Eccles SA, Welch DR. Metastasis: recent discoveries and novel treatment strategies [J]. Lancet, 2007,369(9574): 1742-1757.
4. Nakamura S, Yagata H, Ohno S, et al. Multi-center study evaluating circulating tumor cells as a surrogate for response to treatment and overall survival in metastatic breast cancer [J]. Breast Cancer, 2010,17(3):199-204.
5. Cristofanilli M, Budd GT, Ellis MJ, et al. Circulating tumor cells, disease progression, and survival in metastatic breast cancer [J]. N Engl J Med, 2004,351 (8):781-791.
6. Ring AE, Zabaglo L, Ormerod MG, et al. Detection of circulating epithelial cells in the blood of patients with breast cancer: comparison of three techniques [J]. Br J Cancer, 2005,92(5):906-912.
7. Felton T, Harris GC, Pinder SE, et al. Identification of carcinoma cells in peripheral blood samples of patients with advanced breast carcinoma using RT-PCR amplification of CK7 and MUC1 [J]. Breast, 2004,13(1):35-41.
8. de Cremoux P, Extra JM, Denis MG, et al. Detection of MUC1-expressing mammary carcinoma cells in the peripheral blood of breast cancer patients by real-time polymerase chain reaction [J]. Clin Cancer Res, 2000,6(8):3117-3122.
9. Franceschini G, Terribile D, Magno S, et al. Update in the treatment of locally advanced breast cancer: a multidisciplinary approach [J]. Eur Rev Med Pharmacol Sci, 2007,11(5):283-289.
10. Andreopoulou E, Cristofanilli M. Circulating tumor cells as prognostic marker in metastatic breast cancer [J]. Expert Rev Anticancer Ther, 2010,10(2):171-177.
11. Bosma AJ, Weigelt B, Lambrechts AC, et al. Detection of circulating breast tumor cells by differential expression of marker genes [J]. Clin Cancer Res, 2002,8(6):1871-1877.
12. Garcia-Saenz JA, Martin M, Maestro ML, et al. Circulating tumour cells in locally advanced breast cancer [J]. Clin Transi Oncol, 2009,11(8):544-547.
13. Cristofanilli M. Circulating tumor cells, disease progression, and survival in metastatic breast cancer [J]. Semin Oncol, 2006,33(3 Suppl 9):S9-S14.
14. Budd GT, Cristofanilli M, Ellis MJ, et al. Circulating tumor cells versus imaging-predicting overall survival in metastatic breast cancer [J]. Clin Cancer Res, 2006,12(21):6403-6409.
15. Cristofanilli M, Hayes DF, Budd GT, et al. Circulating tumor cells: a novel prognostic factor for newly diagnosed metastatic breast cancer [J]. J Clin Oncol, 2005,23(7): 1420-1430.
16. Allard WJ, Matera J, Miller MC, et al. Tumor cells circulate in the peripheral blood of all major carcinomas but not in healthy subjects or patients with nonmalignant diseases [J]. Clin Cancer Res, 2004,10(20):6897-6904.
17. Liu MC, Shields PG, Warren RD, et al. Circulating tumor cells: a useful predictor of treatment efficacy in metastatic breast cancer [J]. J Clin Oncol, 2009,27(31):5153-5159.
18. Cristofanilli M, Broglio KR, Guarneri V, et al. Circulating tumor cells in metastatic breast cancer: biologic staging beyond tumor burden [J]. Clin Breast Cancer, 2007,7(6):471-479.
19. Petersen OW, Gudjonsson T, Villadsen R, et al. Epithelial progenitor cell lines as models of normal breast morphogenesis and neoplasia [J]. Cell Prolif, 2003,36 (Suppl 1):33-44.
20. Hayes DF, Smerage J. Is there a role for circulating tumor cells in the management of breast cancer? [J]. Clin Cancer Res, 2008,14(12):3646-3650.
21. Xenidis N, Perraki M, Kafousi M, et al. Predictive and prognostic value of peripheral blood cytokeratin-19 mRNA-positive cells detected by real-time polymerase chain reaction in node-negative breast cancer patients [J]. J Clin Oncol, 2006,24(23):3756-3762.
22. Kasimir-Bauer S. Circulating tumor cells as markers for cancer risk assessment and treatment monitoring [J]. Mol Diagn Ther, 2009, 13(4):209-215.
23. Méhes G, Witt A, Kubista E, et al. Circulating breast cancer cells are frequently apoptotic [J]. Am J Pathol, 2001,159(1):17-20.
24. Balic M, Lin H, Young L, et al. Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype [J]. Clin Cancer Res, 2006,12(19):5615-5621.
25. Abraham BK, Fritz P, McClellan M, et al. Prevalence of CD447 CD24* cells in breast cancer may not be associated with clinical outcome but may favor distant metastasis [J]. Clin Cancer Res, 2005,11(3):1154-1159.