In vivo solid-phase microextraction for single rodent pharmacokinetics studies of carbamazepine and carbamazepine-10,11-epoxide in mice

Journal of Chromatography A

Volumn 1218, Issue 21, 2011, Pages 3367-3375

  Vuckovic, Dajana ^a   de Lannoy, Inés ^b   Gien, Brad ^b   Yang, Yingbo ^b   Musteata, Florin Marcel ^c   Shirey, Robert ^d   Sidisky, Leonard ^d   Pawliszyn, Janusz ^a  

^a UNIVERSITY OF WATERLOO   (Canada)

^b NoAb BioDiscoveries Inc   (Canada)

^c ALBANY COLLEGE OF PHARMACY AND HEALTH SCIENCES   (United States)

^d Supelco Inc   (United States)

Author keywords

Bioanalytical sample preparation; Carbamazepine; Carbamazepine 10,11 epoxide; In vivo solid phase microextraction; Serial sampling in mice; Single rodent pharmacokinetics studies

Indexed keywords

CARBAMAZEPINE; IN-VIVO; SAMPLE PREPARATION; SERIAL SAMPLING IN MICE; SINGLE RODENT PHARMACOKINETICS STUDIES;

AMIDES; ANIMALS; BLOOD; DRUG PRODUCTS; EXTRACTION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; METABOLITES; PHARMACOKINETICS;

SAMPLING;

CARBAMAZEPINE; CARBAMAZEPINE 10,11 OXIDE;

ACCURACY; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CALIBRATION; CONTROLLED STUDY; DESORPTION; DISTRIBUTION VOLUME; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG HALF LIFE; IN VITRO STUDY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; MOUSE; NONHUMAN; PRIORITY JOURNAL; RODENT; SOLID PHASE MICROEXTRACTION; STANDARDIZATION; TANDEM MASS SPECTROMETRY;

ANIMALS; BLOOD SPECIMEN COLLECTION; CARBAMAZEPINE; CHROMATOGRAPHY, LIQUID; EQUIPMENT DESIGN; LINEAR MODELS; MALE; MICE; REPRODUCIBILITY OF RESULTS; SOLID PHASE MICROEXTRACTION; TANDEM MASS SPECTROMETRY;

ANIMALIA; MUS; RODENTIA;

EID: 79954465710     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2010.07.060     Document Type: Article

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