Psychopharmacological Effects of Oxycodone in Volunteers With and Without Generalized Anxiety Disorder

Experimental and Clinical Psychopharmacology

Volumn 19, Issue 2, 2011, Pages 85-94

  Zacny, James P ^a   Gutierrez, Sandra ^a   Kirulus, Karin ^a   McCracken, Stanley G ^b  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

Anxiety disorder; Opioid; Oxycodone; Subjective effects; Volunteer

Indexed keywords

OXYCODONE; PLACEBO;

ADULT; ANXIETY DISORDER; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DRUG EFFECT; FEMALE; HUMAN; MALE; PSYCHOMOTOR ACTIVITY; PSYCHOPHARMACOLOGY;

ADULT; ANALGESICS, OPIOID; ANXIETY; CASE-CONTROL STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; OXYCODONE; PLACEBOS;

EID: 79954462446     PISSN: 10641297     EISSN: 19362293     Source Type: Journal    
DOI: 10.1037/a0022952     Document Type: Article

References (51)

1. Diagnostic and statistical manual of mental disorders 2000, American Psychiatric Association, Author, Washington, DC. 4th ed., text revision.
2. Ashburn M.A., Streisand J.B., Tarver S.D., Mears S.L., Mulder S.M., Floet Wilms A.W., Stanley T.H. Oral transmucosal fentanyl citrate for premedication in paediatric outpatients. Canadian Journal of Anaesthesia 1990, 37:857-866.
3. Baddeley A.D. A three-minute reasoning test based on grammatical transformation. Psychonomic Science 1968, 10:341-342.
4. Boyd C.J., McCabe S.E., Cranford J.A., Young A. Adolescents' motivations to abuse prescription medications. Pediatrics 2006, 118:2472-2480.
5. Brands B., Blake J., Sproule B., Gourlay D., Busto U. Prescription opioid abuse in patients presenting for methadone maintenance treatment. Drug and Alcohol Dependence 2004, 73:199-207.
6. Butler S.F., Budman S.H., Fernandez K., Jamison R.N. Validation of a screener and opioid assessment measure for patients with chronic pain. Pain 2004, 112:65-75.
7. Callaly T., Trauer T., Munro L., Whelan G. Prevalence of psychiatric disorder in a methadone maintenance population. Australian and New Zealand Journal of Psychiatry 2001, 35:601-605.
8. Chutuape M.A., de Wit H. Preferences for ethanol and diazepam in anxious individuals: An evaluation of the self-medication hypothesis. Psychopharmacology 1995, 121:91-103.
9. Colasanti A., Rabiner E.A., Lingford-Hughes A., Nutt D.J. Opioids and anxiety. Journal of Psychopharmacology 2010, doi: 10.1177.0269881110367726.
10. Darke S., Ross J. Polydrug dependence and psychiatric comorbidity among heroin injectors. Drug and Alcohol Dependence 1997, 48:135-141.
11. Derogatis L.R. SCL-90-R: Symptom Checklist-90-R 1975, NCS Pearson, Minneapolis, MN.
12. Derogatis L.R. SCL-90-R: Symptom Checklist-90-R: Administration, scoring and procedures manual 1994, National Computer Systems, Minneapolis, MN. 3rd ed.
13. de Wit H., Uhlenhuth E.H., Hedeker D., McCracken S.G., Johanson C.E. Lack of preference for diazepam in anxious volunteers. Archives of General Psychiatry 1986, 43:533-541.
14. Dowling K., Storr C.L., Chilcoat H.D. Potential influences on initiation and persistence of extramedical prescription pain reliever use in the US population. Clinical Journal of Pain 2006, 22:776-783.
15. First M.B., Spitzer R.L., Gibbon M., Williams J.B.W. Structured Clinical Interview for DSM-IV-Clinical version (SCID-CV) (user's guide and interview) 1997, American Psychiatric Press, Washington, DC.
16. Fraser H.F., van Horn G.D., Martin W.R., Wolbach A.B., Isbell H. Methods for evaluating addiction liability: (a) " attitude" of opiate addicts toward opiate-like drugs, (b) a short-term " direct" addiction test. Journal of Pharmacology and Experimental Therapeutics 1961, 133:371-387.
17. Goodwin R.D., Stayner D.A., Chinman M.J., Wu P., Tebes J.K., Davidson L. The relationship between anxiety and substance use disorders among individuals with severe affective disorders. Comprehensive Psychiatry 2002, 43:245-252.
18. Griffiths R.R., Troisi J.R., Silverman K., Mumford G.K. Multiple-choice procedure: An efficient approach for investigating drug reinforcement in humans. Behavioural Pharmacology 1993, 4:3-13.
19. Haertzen C.A. Development of scales based on patterns of drug effects, using the Addiction Research Center Inventory (ARCI). Psychological Reports 1966, 18:163-194.
20. Hannington-Kiff J.G. Measurement of recovery from outpatient general anaesthesia with a simple ocular test. British Medical Journal 1970, 3:132-135.
21. Helmus T.C., Tancer M., Johanson C.E. Reinforcing effects of diazepam under anxiogenic conditions in individuals with social anxiety. Experimental and Clinical Psychopharmacology 2005, 13:348-356.
22. Jones R.T. Marijuana-induced " high" influence of expectation, setting and previous drug experience. Pharmacological Reviews 1971, 23:359-369.
23. Khantzian E.J. The self-medication hypothesis of addictive disorders: Focus on heroin and cocaine dependence. American Journal of Psychiatry 1985, 212:1259-1264.
24. Kokkevi A., Stefanis C. Drug abuse and psychiatric comorbidity. Comprehensive Psychiatry 1985, 36:329-337.
25. B receptor agonist, antagonizes anxiolytic-like action of morphine in elevated plus-maze. Neuropeptides 1999, 33:63-69.
26. Lasagna L., von Felsinger J.M., Beecher H.K. Drug-induced changes in man: 1. Observations on healthy subjects, chronically ill patients, and " postaddicts." Journal of the American Medical Association 1955, 157:1006-1020.
27. Macaluso A.D., Connelly A.M., Hayes W.B., Holub M.C., Ramsay M.A., Suit C.T., Swygert T.H. Oral transmucosal fentanyl citrate for premedication in adults. Anesthesia and Analgesia 1996, 82:158-161.
28. Martin W.R., Sloan J.W., Sapira J.D., Jasinski D.R. Physiologic, subjective and behavioral effects of amphetamine, methamphetamine, ephedrine, phenmetrazine, and methylphenidate in man. Clinical Pharmacology and Therapeutics 1971, 12:245-258.
29. Martins S.S., Keyes K.M., Storr C.L., Zhu H., Chilcoat H.D. Pathways between nonmedical opioid use/dependence and psychiatric disorders: Results from the National Epidemiologic Survey on Alcohol and Related Disorders. Drug and Alcohol Dependence 2009, 103:16-24.
30. McCabe S.E., Boyd C.J., Cranford J.A., Teter C.J. Motives for nonmedical use of prescription opioids among high school seniors in the United States: Self-treatment and beyond. Archives of Pediatrics & Adolescent Medicine 2009, 163:739-744.
31. McCabe S.E., Boyd C.J., Teter C.J. Subtypes of nonmedical prescription drug misuse. Drug and Alcohol Dependence 2009, 102:63-70.
32. McCabe S.E., Cranford J.A., Boyd C.J., Teter C.J. Motives, diversion and routes of administration associated with nonmedical use of prescription opioids. Addictive Behaviors 2007, 32:562-575.
33. McCracken S.G., de Wit H., Uhlenhuth E.H., Johanson C.E. Preference for diazepam in anxious adults. Journal of Clinical Psychopharmacology 1990, 10:190-196.
34. McNair D.M., Lorr M., Droppleman L.F. Profile of Mood States (manual) 1971, EdITS, San Diego, CA.
35. Nuotto E.J., Korttila K. Evaluation of a new computerized psychomotor test battery: Effects of alcohol. Pharmacology and Toxicology 1991, 68:360-365.
36. Preston K.L., Bigelow G.E., Bickel W.K., Liebson I.A. Drug discrimination in human postaddicts: Agonist-antagonist opioids. Journal of Pharmacology and Experimental Therapeutics 1989, 250:184-196.
37. Rezayof A., Hosseini S., Zarrindast M.R. Effects of morphine in rat behavior in the elevated plus maze: The role of central amygdale dopamine receptors. Behavioural Brain Research 2009, 202:171-178.
38. Roache J.D., Stanley M.A., Creson D.R., Shah N.N., Meisch R.A. Alprazolam-reinforced medication use in outpatients with anxiety. Drug and Alcohol Dependence 1997, 45:143-155.
39. Rounsaville B.J., Weissman M.M., Kleber H., Wilber C. Heterogeneity of psychiatric diagnosis in treated opiate addicts. Archives of General Psychiatry 1982, 39:161-166.
40. Selzer M.L. The Michigan Alcoholism Screening Test: The quest for a new diagnostic instrument. American Journal of Psychiatry 1971, 127:1653-1658.
41. Sheehan D.V., Lecrubier Y., Harnett-Sheehan K., Amorim P., Janavs J., Weiller E., Dunbar G. The Mini International Neuropsychiatric Interview (MINI): The development and validation of a structured diagnostic psychiatric interview. Journal of Clinical Psychiatry 1998, 59(Suppl. 20):22-33.
42. Spielberger C.D., Gorsuch R.L., Lushene R.E. Manual for the State-Trait Anxiety Inventory 1970, Consulting Psychologist Press, Palo Alto, CA.
43. Sproule B.A., Busto U.E., Somer G., Romach M.K., Sellers E.M. Characteristics of dependent and nondependent regular users of codeine. Journal of Clinical Psychopharmacology 1999, 19:367-372.
44. Results from the 2009 National Survey on Drug Use and Health: Detailed Tables 2010, Substance Abuse and Mental Health Services Administration (SAMHSA), Office of Applied Studies, Rockville, MD. Retrieved from http://oas.samhsa.gov/NSDUH/2k9NSDUH/tabs/Sect1peTabs1to10.pdf.
45. Wechsler D. The measurement and appraisal of adult intelligence 1958, Williams and Wilkins, Baltimore, MD.
46. Wilsey B.L., Fishman S.M., Tsodikov A., Ogden C., Symreng I., Ernst A. Psychological comorbidities predicting prescription opioid abuse among patients in chronic pain presenting to the emergency department. Pain Medicine 2008, 9:1107-1117.
47. Zacny J.P., Drum M. Psychopharmacological effects of oxycodone in healthy volunteers: Roles of alcohol-drinking status and sex. Drug and Alcohol Dependence 2010, 107:209-214.
48. Zacny J.P., Gutierrez S. Characterizing the subjective, psychomotor, and physiological effects of oral oxycodone in non-drug-abusing volunteers. Psychopharmacology 2003, 170:242-254.
49. Zacny J.P., Gutierrez S. Subjective, psychomotor, and physiological effects profile of hydrocodone/acetaminophen and oxycodone/acetaminophen combination products. Pain Medicine 2008, 9:433-443.
50. Zacny J.P., Gutierrez S. Within-subject comparison of the psychopharmacological profiles of oral hydrocodone and oxycodone combination products in non-drug-abusing volunteers. Drug and Alcohol Dependence 2009, 101:107-113.
51. Zacny J.P., Lichtor S.A. Within-subject comparison of the psychopharmacological profiles of oral oxycodone and oral morphine in non-drug-abusing volunteers. Psychopharmacology 2008, 196:105-117.