Oxidative stress and PARP activation mediate the NADH-induced decrease in glioma cell survival

International Journal of Physiology, Pathophysiology and Pharmacology

Volumn 3, Issue 1, 2011, Pages 21-28

  Ma, Yingxin ^a   Chen, Heyu ^a   Xia, Weiliang ^a   Ying, Weihai ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Cell death; Glioma cells; NADH; Oxidative stress; Poly(ADP ribose) polymerase

Indexed keywords

ACETYLCYSTEINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; TROLOX C;

ARTICLE; CANCER CELL CULTURE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GLIOMA CELL; OXIDATIVE STRESS;

EID: 79954459786     PISSN: None     EISSN: 19448171     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. +/NADPH in cellular functions and cell death: regulation and biological consequences. Antioxid Redox Signal 2008; 10: 179-206.
2. Zhang Q, Piston DW and Goodman RH. Regulation of corepressor function by nuclear NADH. Science 2002; 295: 1895-1897.
3. Rutter J, Reick M, Wu LC and McKnight SL. Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors. Science 2001; 293: 510-514.
4. Kaplin AI, Snyder SH and Linden DJ. Reduced nicotinamide adenine dinucleotide-selective stimulation of inositol 1,4,5-trisphosphate receptors mediates hypoxic mobilization of calcium. J Neurosci 1996; 16: 2002-2011.
5. 2+ release via locally derived NADH. Proc Natl Acad Sci U S A 2005; 102: 1357-1359.
6. Jaeschke H, Kleinwaechter C and Wendel A. NADH-dependent reductive stress and ferritinbound iron in allyl alcohol-induced lipid peroxidation in vivo: the protective effect of vitamin E. Chem Biol Interact 1992; 81: 57-68.
7. Lu H, Burns D, Garnier P, Wei G, Zhu K and Ying W. P2X7 receptors mediate NADH transport across the plasma membranes of astrocytes. Biochem Biophys Res Commun 2007; 362:946-950.
8. Ziegler M. New functions of a long-known molecule. Emerging roles of NAD in cellular signaling. Eur J Biochem 2000; 267: 1550-1564.
9. + regulatory T cells to extracellular metabolites nicotinamide adenine dinucleotide and ATP: a role for P2X7 receptors. J Immunol 2005; 175: 3075-3083.
10. Haag F, Adriouch S, Brass A, Jung C, Moller S, Scheuplein F, Bannas P, Seman M and Koch-Nolte F. Extracellular NAD and ATP: Partners in immune cell modulation. Purinergic Signal 2007; 3: 71-81.
11. + treatment decreases tumor cell survival by inducing oxidative stress. Front in Biosci (In Press).
12. Virag L and Szabo C. The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol Rev 2002; 54: 375-429.
13. + depletion and mitochondrial permeability transition. J Biol Chem 2004; 279: 18895-18902.
14. + depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death. J Neurosci 2010; 30: 2967-2978.
15. + and NADH in cellular functions and cell death. Front Biosci 2006; 11: 3129-3148.
16. Ying W and Swanson RA. The poly(ADP-ribose) glycohydrolase inhibitor gallotannin blocks oxidative astrocyte death. Neuroreport 2000; 11: 1385-1388.
17. Orrenius S, Gogvadze V and Zhivotovsky B. Mitochondrial oxidative stress: implications for cell death. Annu Rev Pharmacol Toxicol 2007; 47: 143-183.
18. Ying W. Deleterious network hypothesis of apoptosis. Med Hypotheses 1998; 50: 393-398.
19. Re R, Pellegrini N, Proteggente A, Pannala A, Yang M and Rice-Evans C. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic Biol Med 1999; 26: 1231-1237.
20. Martin H, Abadie C, Heyd B, Mantion G, Richert L and Berthelot A. N-acetylcysteine partially reverses oxidative stress and apoptosis exacerbated by Mg-deficiency culturing conditions in primary cultures of rat and human hepatocytes. J Am Coll Nutr 2006; 25: 363-369.
21. Czapski GA, Cakala M, Kopczuk D and Strosznajder JB. Effect of poly(ADP-ribose) polymerase inhibitors on oxidative stress evoked hydroxyl radical level and macromolecules oxidation in cell free system of rat brain cortex. Neurosci Lett 2004; 356: 45-48.
22. D'Amours D, Desnoyers S, D'Silva I and Poirier GG. Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions. Biochem J 1999; 342 (Pt 2): 249-268.
23. Beal MF. Aging, energy, and oxidative stress in neurodegenerative diseases. Ann Neurol 1995; 38: 357-366.
24. Klaunig JE, Kamendulis LM and Hocevar BA. Oxidative stress and oxidative damage in carcinogenesis. Toxicol Pathol 38: 96-109.
25. Harman D. Aging and oxidative stress. J Int Fed Clin Chem 1998; 10: 24-27.
26. + repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes. Biochem Biophys Res Commun 2003; 308: 809-813.
27. Yu SW, Wang H, Poitras MF, Coombs C, Bowers WJ, Federoff HJ, Poirier GG, Dawson TM and Dawson VL. Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosisinducing factor. Science 2002; 297: 259-263.
28. Robins HI, Lassman AB and Khuntia D. Therapeutic advances in malignant glioma: current status and future prospects. Neuroimaging Clin N Am 2009; 19: 647-656.